IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 genes annotated in rat

lower respiratory tract disease

DOID:0050161

A respiratory system disease which involves the lower respiratory tract.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "lower respiratory tract disease" (in gray)

Name	Description	Probability	Func Analog Organism
Muc1	mucin 1, cell surface associated	0.810
Cdcp1	CUB domain containing protein 1	0.574
Scnn1b	sodium channel, nonvoltage-gated 1, beta	0.265	Human
Ly6al	lymphocyte antigen 6 complex, locus A-like	0.206
Prss8	protease, serine, 8	0.141
Tmem79	transmembrane protein 79	0.129
Ly6b	lymphocyte antigen 6 complex, locus B	0.129
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.111
Hnf1b	HNF1 homeobox B	0.107
Tacstd2	tumor-associated calcium signal transducer 2	0.093
Defb4	defensin beta 4	0.078
Gpx2	glutathione peroxidase 2	0.076
Scnn1g	sodium channel, nonvoltage-gated 1, gamma	0.076	Human
Ehf	ets homologous factor	0.070
Gzmb	granzyme B	0.068
Pdzk1ip1	PDZK1 interacting protein 1	0.067
Foxq1	forkhead box Q1	0.067
Slc23a3	solute carrier family 23 (nucleobase transporters), member 3	0.062
Ear11	eosinophil-associated, ribonuclease A family, member 11	0.060
Cdh17	cadherin 17	0.060
Scnn1a	sodium channel, nonvoltage-gated 1 alpha	0.058	Human
Muc4	mucin 4, cell surface associated	0.056
Aqp5	aquaporin 5	0.047
Cyp4a8	cytochrome P450, family 4, subfamily a, polypeptide 8	0.041
Sftpa1	surfactant protein A1	0.041	Human
Irs3	insulin receptor substrate 3	0.039
Atp6v1g3	ATPase, H+ transporting, lysosomal V1 subunit G3	0.038
RGD1562234	similar to S100 calcium-binding protein, ventral prostate	0.036
Lrp2	low density lipoprotein-related protein 2	0.035
Fut2	fucosyltransferase 2 (secretor status included)	0.033
Pyy	peptide YY (mapped)	0.031
Mcpt4	mast cell protease 4	0.030
Fam148b	family with sequence similarity 148, member B	0.029
Cngb1	cyclic nucleotide gated channel beta 1	0.027
Msx2	msh homeobox 2	0.026
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.026
Tmem101	transmembrane protein 101	0.026
Cldn7	claudin 7	0.025
Samd4b	sterile alpha motif domain containing 4B	0.024
RGD1305347	similar to RIKEN cDNA 2610528J11	0.024
Ager	advanced glycosylation end product-specific receptor	0.024
Gp2	glycoprotein 2 (zymogen granule membrane)	0.023
Met	met proto-oncogene	0.019
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.019
Art2	ADP-ribosyltransferase 2	0.019
Foxa2	forkhead box A2	0.019
Psgb1	pregnancy-specific beta 1-glycoprotein	0.019
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.019
Foxd3	forkhead box D3	0.018
Tp63	tumor protein p63	0.018
Slc44a4	solute carrier family 44, member 4	0.018
Slc13a2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.018
Prss2	protease, serine, 2	0.017
Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	0.017
Lgals4	lectin, galactoside-binding, soluble, 4	0.016
Krt1-5	keratin complex 1, acidic, gene 5	0.016
Vtcn1	V-set domain containing T cell activation inhibitor 1	0.016
Slc9a4	solute carrier family 9 (sodium/hydrogen exchanger), member 4	0.016
Lrch4	leucine-rich repeats and calponin homology (CH) domain containing 4	0.016
Cma1	chymase 1, mast cell	0.015
Il1r2	interleukin 1 receptor, type II	0.015
Fabp2	fatty acid binding protein 2, intestinal	0.015
Reg3a	regenerating islet-derived 3 alpha	0.015
Elf3	E74-like factor 3	0.015
RGD1310262	hypothetical LOC304650	0.015
Chia	chitinase, acidic	0.015
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.015
Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.015
Hoxa2	homeo box A2	0.015
Ccl20	chemokine (C-C motif) ligand 20	0.014
Mettl7b	methyltransferase like 7B	0.014
Adrb3	adrenergic, beta-3-, receptor	0.014
Prol1	proline rich, lacrimal 1	0.014
Gnmt	glycine N-methyltransferase	0.013
Mmp7	matrix metallopeptidase 7	0.013
Enah	enabled homolog (Drosophila)	0.013
Lhx5	LIM homeobox 5	0.013
LOC686432	hypothetical protein LOC686432	0.013
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.012
Mmp3	matrix metallopeptidase 3	0.012
Cxcl3	chemokine (C-X-C motif) ligand 3	0.012
Bhlha15	basic helix-loop-helix family, member a15	0.012
S100g	S100 calcium binding protein G	0.012
Zfp37	zinc finger protein 37	0.012
LOC360479	similar to hypothetical protein	0.012
Vom1r100	vomeronasal 1 receptor 100	0.011
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.011
Pou2f3	POU class 2 homeobox 3	0.011
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.011
Sostdc1	sclerostin domain containing 1	0.011
Ccl28	chemokine (C-C motif) ligand 28	0.011
Mylk2	myosin light chain kinase 2	0.011
RGD1561149	similar to mKIAA1522 protein	0.011
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.011
Olr1078	olfactory receptor 1078	0.011
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.011
LOC286960	preprotrypsinogen IV	0.011
RGD1564163	similar to RIKEN cDNA 1700025K23	0.011
Rps3a	ribosomal protein S3a	0.011
Sell	selectin L	0.010
Nppb	natriuretic peptide precursor B	0.010
Clec9a	C-type lectin domain family 9, member a	0.010