0 genes annotated in rat
An organic acidemia that is caused by a deficiency of decarboxylase leading to high concentrations of valine, leucine, isoleucine, and alloisoleucine in the blood, urine, and cerebrospinal fluid and characterized by an odor of maple syrup to the urine, vomiting, hypertonicity, severe mental retardation, seizures, and eventually death unless the condition is treated with dietary measures.
In addition to gene-name show these genes:
Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.
|Name||Description||Probability||Func Analog Organism|
|Ndufs1||NADH dehydrogenase (ubiquinone) Fe-S protein 1||0.069|
|Fh1||fumarate hydratase 1||0.030|
|Idh3B||isocitrate dehydrogenase 3 (NAD+) beta||0.029|
|Ptp4a1||protein tyrosine phosphatase type IVA, member 1||0.021|
|Aifm1||apoptosis-inducing factor, mitochondrion-associated 1||0.019|
|Uqcrc2||ubiquinol cytochrome c reductase core protein 2||0.017|
|Mccc2||methylcrotonoyl-Coenzyme A carboxylase 2 (beta)||0.016|
|Sdha||succinate dehydrogenase complex, subunit A, flavoprotein (Fp)||0.015|
|Eif3j||eukaryotic translation initiation factor 3, subunit J||0.012|
|Pdha1||pyruvate dehydrogenase (lipoamide) alpha 1||0.011|