IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 genes annotated in rat

amino acid metabolic disorder

DOID:9252

An inherited metabolic disorders which impair the synthesis and degradation of amino acids.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "amino acid metabolic disorder" (in gray)

Name	Description	Probability	Func Analog Organism
Echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.756
Pcca	propionyl-coenzyme A carboxylase, alpha polypeptide	0.723
Mccc2	methylcrotonoyl-Coenzyme A carboxylase 2 (beta)	0.704	Human
Adk	adenosine kinase	0.488
Gcdh	glutaryl-Coenzyme A dehydrogenase	0.485
Prdx3	peroxiredoxin 3	0.448
Uqcrc2	ubiquinol cytochrome c reductase core protein 2	0.438
Pdha1	pyruvate dehydrogenase (lipoamide) alpha 1	0.291
Cabc1	chaperone, ABC1 activity of bc1 complex homolog (S. pombe)	0.253
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.221
Acat1	acetyl-coenzyme A acetyltransferase 1	0.175
Aifm1	apoptosis-inducing factor, mitochondrion-associated 1	0.172
Psat1	phosphoserine aminotransferase 1	0.164
Ivd	isovaleryl coenzyme A dehydrogenase	0.155	Human
Bckdha	branched chain ketoacid dehydrogenase E1, alpha polypeptide	0.105
Ndufs1	NADH dehydrogenase (ubiquinone) Fe-S protein 1	0.099
Suclg2	succinate-CoA ligase, GDP-forming, beta subunit	0.095
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.082
RGD1303003	homolog of zebrafish ES1	0.076
Bckdhb	branched chain keto acid dehydrogenase E1, beta polypeptide	0.075	Human
Aldh6a1	aldehyde dehydrogenase 6 family, member A1	0.071
Clpx	ClpX caseinolytic peptidase X homolog (E. coli)	0.066
Bcat2	branched chain aminotransferase 2, mitochondrial	0.060
Mut	methylmalonyl-Coenzyme A mutase	0.055
Uba3	ubiquitin-like modifier activating enzyme 3	0.052
Idh3B	isocitrate dehydrogenase 3 (NAD+) beta	0.042
Tst	thiosulfate sulfurtransferase	0.041
Ndufaf4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4	0.041
Fahd2a	fumarylacetoacetate hydrolase domain containing 2A	0.040
Mpst	mercaptopyruvate sulfurtransferase	0.040
Hibadh	3-hydroxyisobutyrate dehydrogenase	0.037
Mccc1	methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)	0.036	Human
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.036
Sucla2	succinate-CoA ligase, ADP-forming, beta subunit	0.035
Clybl	citrate lyase beta like	0.035
Gc	group specific component	0.033
Lypla1	lysophospholipase 1	0.032
Mdh1	malate dehydrogenase 1, NAD (soluble)	0.032
Gstk1	glutathione S-transferase kappa 1	0.031
Aldh2	aldehyde dehydrogenase 2 family (mitochondrial)	0.031
Fh1	fumarate hydratase 1	0.030
Nnt	nicotinamide nucleotide transhydrogenase	0.030
Foxn3	forkhead box N3	0.029
Echdc2	enoyl Coenzyme A hydratase domain containing 2	0.029
Sod2	superoxide dismutase 2, mitochondrial	0.029
Pfkm	phosphofructokinase, muscle	0.028
Ugp2	UDP-glucose pyrophosphorylase 2	0.026
Bckdk	branched chain ketoacid dehydrogenase kinase	0.026
Gstm7	glutathione S-transferase, mu 7	0.026
Ube4a	ubiquitination factor E4A (UFD2 homolog, yeast)	0.025
Idh2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	0.025	Human
Klf15	Kruppel-like factor 15	0.024
Sfxn1	sideroflexin 1	0.023
Nfs1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)	0.023
Etfa	electron-transfer-flavoprotein, alpha polypeptide	0.023
Akr7a2	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)	0.023
Rab5b	RAB5B, member RAS oncogene family	0.023
Eif4ebp1	eukaryotic translation initiation factor 4E binding protein 1	0.022
Idh3g	isocitrate dehydrogenase 3 (NAD), gamma	0.022
Ptp4a1	protein tyrosine phosphatase type IVA, member 1	0.021
Tob1	transducer of ErbB-2.1	0.021
Ass1	argininosuccinate synthetase 1	0.020
Gfm1	G elongation factor, mitochondrial 1	0.019
Gjb1	gap junction protein, beta 1	0.019
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.019
Ipo7	importin 7	0.017
Cox15	COX15 homolog, cytochrome c oxidase assembly protein (yeast)	0.017
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.016
Tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.016
Acsl1	acyl-CoA synthetase long-chain family member 1	0.016
Bhmt	betaine-homocysteine methyltransferase	0.016
LOC100361841	kynurenine aminotransferase III-like	0.016
Nampt	nicotinamide phosphoribosyltransferase	0.015
Ube2b	ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae)	0.015
Fetub	fetuin B	0.015
Pdhb	pyruvate dehydrogenase (lipoamide) beta	0.015
Pxmp2	peroxisomal membrane protein 2	0.014
Ndufa10l1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 1	0.014
Osbpl1a	oxysterol binding protein-like 1A	0.014
Slc3a2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.014
Dbt	dihydrolipoamide branched chain transacylase E2	0.014	Human
Snx2	sorting nexin 2	0.014
Selenbp1	selenium binding protein 1	0.013
Ccng1	cyclin G1	0.013
Cdadc1	cytidine and dCMP deaminase domain containing 1	0.013
Pdhx	pyruvate dehydrogenase complex, component X	0.013
Fga	fibrinogen alpha chain	0.013
Acadm	acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	0.013
Ivns1abp	influenza virus NS1A binding protein	0.013
Ak3	adenylate kinase 3	0.013
Gpt	glutamic-pyruvate transaminase (alanine aminotransferase)	0.013
Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	0.012
Pet112l	PET112-like (yeast)	0.012
Dlat	dihydrolipoamide S-acetyltransferase	0.012
Cyp2t1	cytochrome P450, family 2, subfamily t, polypeptide 1	0.012
Asns	asparagine synthetase	0.012
Eif4a2	eukaryotic translation initiation factor 4A, isoform 2	0.012
Aldh1l1	aldehyde dehydrogenase 1 family, member L1	0.012
Eif3j	eukaryotic translation initiation factor 3, subunit J	0.012
Pc	pyruvate carboxylase	0.012
Fmo1	flavin containing monooxygenase 1	0.012
Mlycd	malonyl-CoA decarboxylase	0.011
Gulo	gulonolactone (L-) oxidase	0.011
Plaa	phospholipase A2, activating protein	0.011
Abhd14b	abhydrolase domain containing 14b	0.011
Cmpk1	cytidine monophosphate (UMP-CMP) kinase 1	0.011
Acadsb	acyl-Coenzyme A dehydrogenase, short/branched chain	0.011
Hsd17b10	hydroxysteroid (17-beta) dehydrogenase 10	0.011
Lrpprc	leucine-rich PPR-motif containing	0.011
Entpd2	ectonucleoside triphosphate diphosphohydrolase 2	0.011
Gnmt	glycine N-methyltransferase	0.011
Dcxr	dicarbonyl L-xylulose reductase	0.011
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.011
Phldb1	pleckstrin homology-like domain, family B, member 1	0.011
Mmachc	methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria	0.011
Pccb	propionyl coenzyme A carboxylase, beta polypeptide	0.011	Human
Lactb	lactamase, beta	0.010
Ndufs2	NADH dehydrogenase (ubiquinone) Fe-S protein 2	0.010
Mipep	mitochondrial intermediate peptidase	0.010
Sel1l	sel-1 suppressor of lin-12-like (C. elegans)	0.010
Ndrg2	N-myc downstream regulated gene 2	0.010
Mat1a	methionine adenosyltransferase I, alpha	0.010
Ccdc47	coiled-coil domain containing 47	0.010
Selt	selenoprotein T	0.010
Aldob	aldolase B, fructose-bisphosphate	0.010