IMP
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Rattus norvegicus
0 genes annotated in rat
organic acidemia
DOID:0060159
An amino acid metabolic disorder that disrupts normal amino acid metabolism causing a building up of branched-chain amino acids.
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In addition to gene-name show these genes:
Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Adk | adenosine kinase | 0.488 | ||
| Prdx3 | peroxiredoxin 3 | 0.448 | ||
| Uqcrc2 | ubiquinol cytochrome c reductase core protein 2 | 0.438 | ||
| Pdha1 | pyruvate dehydrogenase (lipoamide) alpha 1 | 0.291 | ||
| Echs1 | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 0.258 | ||
| Sdha | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.221 | ||
| Gcdh | glutaryl-Coenzyme A dehydrogenase | 0.180 | ||
| Aifm1 | apoptosis-inducing factor, mitochondrion-associated 1 | 0.172 | ||
| Ivd | isovaleryl coenzyme A dehydrogenase | 0.155 | Human | |
| Acat1 | acetyl-coenzyme A acetyltransferase 1 | 0.117 | ||
| Pcca | propionyl-coenzyme A carboxylase, alpha polypeptide | 0.100 | ||
| Ndufs1 | NADH dehydrogenase (ubiquinone) Fe-S protein 1 | 0.099 | ||
| Ppp1cb | protein phosphatase 1, catalytic subunit, beta isoform | 0.082 | ||
| Aldh6a1 | aldehyde dehydrogenase 6 family, member A1 | 0.071 | ||
| Bckdhb | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.066 | Human | |
| Clpx | ClpX caseinolytic peptidase X homolog (E. coli) | 0.066 | ||
| Mut | methylmalonyl-Coenzyme A mutase | 0.055 | ||
| Mccc2 | methylcrotonoyl-Coenzyme A carboxylase 2 (beta) | 0.055 | ||
| Uba3 | ubiquitin-like modifier activating enzyme 3 | 0.052 | ||
| Idh3B | isocitrate dehydrogenase 3 (NAD+) beta | 0.042 | ||
| Tst | thiosulfate sulfurtransferase | 0.039 | ||
| Atp5a1 | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 0.036 | ||
| Sucla2 | succinate-CoA ligase, ADP-forming, beta subunit | 0.035 | ||
| Lypla1 | lysophospholipase 1 | 0.032 | ||
| Aldh2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.031 | ||
| Fh1 | fumarate hydratase 1 | 0.030 | ||
| Sod2 | superoxide dismutase 2, mitochondrial | 0.029 | ||
| Ugp2 | UDP-glucose pyrophosphorylase 2 | 0.026 | ||
| Ube4a | ubiquitination factor E4A (UFD2 homolog, yeast) | 0.025 | ||
| Nfs1 | NFS1 nitrogen fixation 1 homolog (S. cerevisiae) | 0.023 | ||
| Etfa | electron-transfer-flavoprotein, alpha polypeptide | 0.023 | ||
| Akr7a2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.023 | ||
| Ptp4a1 | protein tyrosine phosphatase type IVA, member 1 | 0.021 | ||
| Tob1 | transducer of ErbB-2.1 | 0.021 | ||
| Hibadh | 3-hydroxyisobutyrate dehydrogenase | 0.020 | ||
| Gstk1 | glutathione S-transferase kappa 1 | 0.020 | ||
| Gfm1 | G elongation factor, mitochondrial 1 | 0.019 | ||
| Ipo7 | importin 7 | 0.017 | ||
| Tax1bp1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.016 | ||
| Nnt | nicotinamide nucleotide transhydrogenase | 0.015 | ||
| Nampt | nicotinamide phosphoribosyltransferase | 0.015 | ||
| Ube2b | ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae) | 0.015 | ||
| Bckdha | branched chain ketoacid dehydrogenase E1, alpha polypeptide | 0.015 | ||
| Pdhb | pyruvate dehydrogenase (lipoamide) beta | 0.015 | ||
| RGD1303003 | homolog of zebrafish ES1 | 0.014 | ||
| Snx2 | sorting nexin 2 | 0.014 | ||
| Ccng1 | cyclin G1 | 0.013 | ||
| Cdadc1 | cytidine and dCMP deaminase domain containing 1 | 0.013 | ||
| Pdhx | pyruvate dehydrogenase complex, component X | 0.013 | ||
| Acadm | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 0.013 | ||
| Ivns1abp | influenza virus NS1A binding protein | 0.013 | ||
| Dlat | dihydrolipoamide S-acetyltransferase | 0.012 | ||
| Cabc1 | chaperone, ABC1 activity of bc1 complex homolog (S. pombe) | 0.012 | ||
| Eif4a2 | eukaryotic translation initiation factor 4A, isoform 2 | 0.012 | ||
| Clybl | citrate lyase beta like | 0.012 | ||
| Aldh1l1 | aldehyde dehydrogenase 1 family, member L1 | 0.012 | ||
| Eif3j | eukaryotic translation initiation factor 3, subunit J | 0.012 | ||
| Fahd2a | fumarylacetoacetate hydrolase domain containing 2A | 0.011 | ||
| Acsl1 | acyl-CoA synthetase long-chain family member 1 | 0.011 | ||
| Plaa | phospholipase A2, activating protein | 0.011 | ||
| Cmpk1 | cytidine monophosphate (UMP-CMP) kinase 1 | 0.011 | ||
| Acadsb | acyl-Coenzyme A dehydrogenase, short/branched chain | 0.011 | ||
| Lrpprc | leucine-rich PPR-motif containing | 0.011 | ||
| Ndufs2 | NADH dehydrogenase (ubiquinone) Fe-S protein 2 | 0.010 | ||
| Pc | pyruvate carboxylase | 0.010 | ||
| Ccdc47 | coiled-coil domain containing 47 | 0.010 | ||
| Selt | selenoprotein T | 0.010 |