IMP: Integrative Multi-species Prediction

Rattus norvegicus

2 genes annotated in rat

alpha beta t cell differentiation

The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "alpha beta t cell differentiation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "alpha beta t cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Gimap4	GTPase, IMAP family member 4	0.133
Apol3	apolipoprotein L, 3	0.091
Ddr1	discoidin domain receptor tyrosine kinase 1	0.086
Gja4	gap junction protein, alpha 4	0.052
Hmha1	histocompatibility (minor) HA-1	0.050
Cd37	CD37 molecule	0.048
Efnb1	ephrin B1	0.047
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.044
Cd5	Cd5 molecule	0.044
Itgb7	integrin, beta 7	0.043
Tgfbr3	transforming growth factor, beta receptor III	0.038
Stat6	signal transducer and activator of transcription 6	0.038	Mouse
Hdac7	histone deacetylase 7	0.034
Arhgap25	Rho GTPase activating protein 25	0.032
Anpep	alanyl (membrane) aminopeptidase	0.031
Cd2	Cd2 molecule	0.030
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.029
Pecam1	platelet/endothelial cell adhesion molecule 1	0.029
Tek	TEK tyrosine kinase, endothelial	0.029
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.028
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.028
Rxra	retinoid X receptor alpha	0.027
Il2rg	interleukin 2 receptor, gamma	0.026
Spn	sialophorin	0.025
Sh2d1a	SH2 domain protein 1A	0.024
Map3k3	mitogen activated protein kinase kinase kinase 3	0.023
Rhoh	ras homolog gene family, member H	0.023
Mapk7	mitogen-activated protein kinase 7	0.023
Psd4	pleckstrin and Sec7 domain containing 4	0.023
Ncr3	natural cytotoxicity triggering receptor 3	0.022
Gpr4	G protein-coupled receptor 4	0.022
Cd247	Cd247 molecule	0.020
Egfl7	EGF-like-domain, multiple 7	0.020
Tfeb	transcription factor EB	0.020
Prkch	protein kinase C, eta	0.019
Arhgap4	Rho GTPase activating protein 4	0.018
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.018
LOC100364854	similar to RIKEN cDNA A430107P09 gene-like	0.018
Nfic	nuclear factor I/C	0.018
Hdac1l	histone deacetylase 1-like	0.018
Socs3	suppressor of cytokine signaling 3	0.018
Psen1	presenilin 1	0.017
Olr1469	olfactory receptor Olr1469	0.017
Smad7	SMAD family member 7	0.016
Nos3	nitric oxide synthase 3, endothelial cell	0.016
LOC363326	hypothetical LOC363326	0.016
Csk	c-src tyrosine kinase	0.015
Epn1	Epsin 1	0.015
Plekhg2	pleckstrin homology domain containing, family G (with RhoGef domain) member 2	0.015
Serpinb6b	serine (or cysteine) peptidase inhibitor, clade B, member 6b	0.015
Triobp	TRIO and F-actin binding protein	0.015
Jund	jun D proto-oncogene	0.015
Bin2	bridging integrator 2	0.015
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.015
Podxl	podocalyxin-like	0.014
Bak1	BCL2-antagonist/killer 1	0.014
Btk	Bruton agammaglobulinemia tyrosine kinase	0.014
Gata2	GATA binding protein 2	0.014
Sdc3	syndecan 3	0.014
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.014
Cd3g	CD3 molecule, gamma	0.013
Ctla2a	cytotoxic T lymphocyte-associated protein 2 alpha	0.013
Hcst	hematopoietic cell signal transducer	0.013
Sept1	septin 1	0.013
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.013
Faim3	Fas apoptotic inhibitory molecule 3	0.013
Arhgef15	Rho guanine nucleotide exchange factor (GEF) 15	0.013
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.013
Cdc42bpb	CDC42 binding protein kinase beta (DMPK-like)	0.013
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.012
Cd4	Cd4 molecule	0.012
Cnr2	cannabinoid receptor 2 (macrophage)	0.012
Wasf2	WAS protein family, member 2	0.012
Gulo	gulonolactone (L-) oxidase	0.012
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.012
Gpsm3	G-protein signaling modulator 3 (AGS3-like, C. elegans)	0.012
Trim25	tripartite motif-containing 25	0.012
Ltb	lymphotoxin beta (TNF superfamily, member 3)	0.012
Zfp36	zinc finger protein 36	0.012
Cish	cytokine inducible SH2-containing protein	0.012
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.012
Scarf2	scavenger receptor class F, member 2	0.011
Emcn	endomucin	0.011
Ralgds	ral guanine nucleotide dissociation stimulator	0.011
Ccl5	chemokine (C-C motif) ligand 5	0.011
Sbno2	strawberry notch homolog 2 (Drosophila)	0.011
Lck	lymphocyte-specific protein tyrosine kinase	0.011
Lgals2	lectin, galactoside-binding, soluble, 2	0.011
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.011
Ccdc69	coiled-coil domain containing 69	0.011
Grap	GRB2-related adaptor protein	0.011
Ccl21	chemokine (C-C motif) ligand 21	0.011
Cd69	Cd69 molecule	0.011
Prickle3	prickle homolog 3 (Drosophila)	0.011
Ptprcap	protein tyrosine phosphatase, receptor type, C-associated protein	0.011
Dll4	delta-like 4 (Drosophila)	0.011
RT1-N3	RT1 class Ib, locus N3	0.010
Klf13	Kruppel-like factor 13	0.010
Actn4	actinin alpha 4	0.010
Zap70	zeta-chain (TCR) associated protein kinase	0.010
LOC100365152	adaptor-related protein complex 1, gamma 2 subunit-like	0.010
Plcg2	phospholipase C, gamma 2	0.010
Fosl2	fos-like antigen 2	0.010