IMP
Process View
leydig cell differentiation
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.
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Click on a gene's description to view its network relationships with genes known to be involved in "leydig cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Prdx1 | peroxiredoxin 1 | 0.627 | ||
| Ddt | D-dopachrome tautomerase | 0.379 | ||
| Ddr2 | discoidin domain receptor tyrosine kinase 2 | 0.274 | ||
| Dbi | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 0.202 | ||
| Decr1 | 2,4-dienoyl CoA reductase 1, mitochondrial | 0.174 | ||
| Akr1c18 | aldo-keto reductase family 1, member C18 | 0.171 | ||
| Gsta3 | glutathione S-transferase A3 | 0.162 | ||
| Etfb | electron-transfer-flavoprotein, beta polypeptide | 0.157 | ||
| Mettl7b | methyltransferase like 7B | 0.156 | ||
| Gsta4 | glutathione S-transferase alpha 4 | 0.144 | ||
| Scnn1g | sodium channel, nonvoltage-gated 1, gamma | 0.139 | ||
| Star | steroidogenic acute regulatory protein | 0.136 | ||
| Hsd3b1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 0.131 | ||
| Slc13a2 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 | 0.122 | ||
| Cyp4a10 | cytochrome P450, family 4, subfamily a, polypeptide 10 | 0.114 | ||
| Rala | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.113 | ||
| Hes2 | hairy and enhancer of split 2 (Drosophila) | 0.098 | ||
| Tff2 | trefoil factor 2 | 0.087 | ||
| Naglt1 | Na+ dependent glucose transporter 1 | 0.086 | ||
| Ephx1 | epoxide hydrolase 1, microsomal | 0.084 | ||
| Cyp11a1 | cytochrome P450, family 11, subfamily a, polypeptide 1 | 0.080 | ||
| Lama2 | laminin, alpha 2 | 0.078 | ||
| Nr5a2 | nuclear receptor subfamily 5, group A, member 2 | 0.069 | ||
| Rln1 | relaxin 1 | 0.069 | ||
| Scp2 | sterol carrier protein 2 | 0.069 | ||
| Pla2g5 | phospholipase A2, group V | 0.067 | ||
| Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.064 | ||
| Krt34 | keratin 34 | 0.064 | ||
| Mamdc4 | MAM domain containing 4 | 0.060 | ||
| Cyb5a | cytochrome b5 type A (microsomal) | 0.054 | ||
| Gabrg3 | gamma-aminobutyric acid (GABA) A receptor, gamma 3 | 0.054 | ||
| Slc22a25 | solute carrier family 22, member 25 | 0.052 | ||
| Mosc2 | MOCO sulphurase C-terminal domain containing 2 | 0.051 | ||
| Echs1 | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 0.050 | ||
| Slc9a4 | solute carrier family 9 (sodium/hydrogen exchanger), member 4 | 0.049 | ||
| Atxn1 | ataxin 1 | 0.046 | ||
| Hrh2 | histamine receptor H 2 | 0.045 | ||
| Cela2a | chymotrypsin-like elastase family, member 2A | 0.042 | ||
| Defb4 | defensin beta 4 | 0.041 | ||
| Prl7d1 | prolactin family 7, subfamily d, member 1 | 0.041 | ||
| Apob | apolipoprotein B | 0.039 | ||
| Gjb3 | gap junction protein, beta 3 | 0.039 | ||
| Hpd | 4-hydroxyphenylpyruvate dioxygenase | 0.039 | ||
| Sod1 | superoxide dismutase 1, soluble | 0.039 | ||
| Acadm | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 0.039 | ||
| Hsd3b6 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 | 0.038 | ||
| Prss3 | protease, serine, 3 | 0.038 | ||
| Cyp1a2 | cytochrome P450, family 1, subfamily a, polypeptide 2 | 0.036 | ||
| Omd | osteomodulin | 0.036 | ||
| Capn9 | calpain 9 | 0.035 | ||
| Galnt5 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) | 0.035 | ||
| Lamp2 | lysosomal-associated membrane protein 2 | 0.033 | ||
| LOC691807 | hypothetical protein LOC691807 | 0.033 | ||
| Vom1r97 | vomeronasal 1 receptor 97 | 0.032 | ||
| RGD1304731 | similar to RIKEN cDNA 5330437I02 gene | 0.031 | ||
| Axl | Axl receptor tyrosine kinase | 0.030 | ||
| Zfp36l1 | zinc finger protein 36, C3H type-like 1 | 0.029 | ||
| Slc7a2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.029 | ||
| Wipf1 | WAS/WASL interacting protein family, member 1 | 0.029 | ||
| Aqp8 | aquaporin 8 | 0.029 | ||
| Abcb11 | ATP-binding cassette, subfamily B (MDR/TAP), member 11 | 0.029 | ||
| Cyp17a1 | cytochrome P450, family 17, subfamily a, polypeptide 1 | 0.029 | ||
| Cyp2b1 | cytochrome P450, family 2, subfamily b, polypeptide 1 | 0.028 | ||
| Grik3 | glutamate receptor, ionotropic, kainate 3 | 0.028 | ||
| Pla2g1b | phospholipase A2, group IB, pancreas | 0.027 | ||
| Itga1 | integrin, alpha 1 | 0.027 | ||
| Gpx1 | glutathione peroxidase 1 | 0.026 | ||
| Bdh2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.025 | ||
| Gstp1 | glutathione S-transferase pi 1 | 0.025 | ||
| Col10a1 | collagen, type X, alpha 1 | 0.025 | ||
| Prlr | prolactin receptor | 0.024 | ||
| Fkbp9 | FK506 binding protein 9 | 0.024 | ||
| Akap4 | A kinase (PRKA) anchor protein 4 | 0.024 | ||
| Fcer1a | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.024 | ||
| Cyp4f1 | cytochrome P450, family 4, subfamily f, polypeptide 1 | 0.024 | ||
| Cst12 | cystatin 12 | 0.024 | ||
| Crisp2 | cysteine-rich secretory protein 2 | 0.024 | ||
| Chrna3 | cholinergic receptor, nicotinic, alpha 3 | 0.023 | ||
| Naaladl1 | N-acetylated alpha-linked acidic dipeptidase-like 1 | 0.023 | ||
| Sdc1 | syndecan 1 | 0.023 | ||
| Olr1867 | olfactory receptor 1867 | 0.022 | ||
| Sdhc | succinate dehydrogenase complex, subunit C, integral membrane protein | 0.022 | ||
| Cox16 | COX16 cytochrome c oxidase assembly homolog | 0.022 | ||
| Nrp1 | neuropilin 1 | 0.022 | ||
| Dpep1 | dipeptidase 1 (renal) | 0.022 | ||
| Nos1 | nitric oxide synthase 1, neuronal | 0.022 | ||
| Faslg | Fas ligand (TNF superfamily, member 6) | 0.021 | ||
| Sult1a1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | 0.021 | ||
| Robld3 | roadblock domain containing 3 | 0.021 | ||
| Acaa2 | acetyl-Coenzyme A acyltransferase 2 | 0.021 | ||
| Calcr | calcitonin receptor | 0.021 | ||
| Prm3 | protamine 3 | 0.021 | ||
| Cyp2d4 | cytochrome P450, family 2, subfamily d, polypeptide 4 | 0.021 | ||
| Ech1 | enoyl coenzyme A hydratase 1, peroxisomal | 0.021 | ||
| Umod | uromodulin | 0.021 | ||
| Acat3 | acetyl-Coenzyme A acetyltransferase 3 | 0.021 | ||
| Tacr2 | tachykinin receptor 2 | 0.020 | ||
| Idh1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.020 | ||
| Bcap31 | B-cell receptor-associated protein 31 | 0.020 | ||
| Ugt1a6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.020 | ||
| Atp4b | ATPase, H+/K+ exchanging, beta polypeptide | 0.020 | ||
| RGD1564560 | similar to RCK | 0.020 | ||
| Gnrhr | gonadotropin releasing hormone receptor | 0.019 | ||
| Sc4mol | sterol-C4-methyl oxidase-like | 0.019 | ||
| ND4 | NADH dehydrogenase subunit 4 | 0.019 | ||
| A1i3 | alpha-1-inhibitor III | 0.019 | ||
| LOC100360205 | palladin | 0.019 | ||
| Marcks | myristoylated alanine rich protein kinase C substrate | 0.019 | ||
| Slc14a2 | solute carrier family 14 (urea transporter), member 2 | 0.019 | ||
| Slc7a3 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 | 0.018 | ||
| Angpt2 | angiopoietin 2 | 0.018 | ||
| Hlf | hepatic leukemia factor | 0.018 | ||
| Znf575 | zinc finger protein 575 | 0.018 | ||
| C2cd4d | C2 calcium-dependent domain containing 4D | 0.018 | ||
| Adra2b | adrenergic, alpha-2B-, receptor | 0.018 | ||
| Svs5 | seminal vesicle secretory protein 5 | 0.017 | ||
| Drd5 | dopamine receptor D5 | 0.017 | ||
| Klk8 | kallikrein related-peptidase 8 | 0.017 | ||
| Hoxd9 | homeo box D9 | 0.017 | ||
| Hsd17b4 | hydroxysteroid (17-beta) dehydrogenase 4 | 0.017 | ||
| Tspan31 | tetraspanin 31 | 0.017 | ||
| Tore | trispanning orphan | 0.017 | ||
| Padi4 | peptidyl arginine deiminase, type IV | 0.017 | ||
| Tex19 | testis expressed 19 | 0.017 | ||
| Tacr3 | tachykinin receptor 3 | 0.017 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.016 | ||
| Casq2 | calsequestrin 2 (cardiac muscle) | 0.016 | ||
| Kcnj15 | potassium inwardly-rectifying channel, subfamily J, member 15 | 0.016 | ||
| Slc6a6 | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | 0.016 | ||
| Mcm6 | minichromosome maintenance complex component 6 | 0.016 | ||
| Chrna1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | 0.015 | ||
| Cldn19 | claudin 19 | 0.015 | ||
| Hbg1 | hemoglobin, gamma A | 0.015 | ||
| Ptgr1 | prostaglandin reductase 1 | 0.015 | ||
| Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | 0.015 | ||
| Slc22a1 | solute carrier family 22 (organic cation transporter), member 1 | 0.015 | ||
| Stra6 | stimulated by retinoic acid gene 6 | 0.015 | ||
| Pnlip | pancreatic lipase | 0.015 | ||
| Slc12a1 | solute carrier family 12 (sodium/potassium/chloride transporters), member 1 | 0.015 | ||
| Tshb | thyroid stimulating hormone, beta | 0.015 | ||
| Sult1c3 | sulfotransferase family, cytosolic, 1C, member 3 | 0.015 | ||
| Madcam1 | mucosal vascular addressin cell adhesion molecule 1 | 0.015 | ||
| Agtr2 | angiotensin II receptor, type 2 | 0.015 | ||
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.015 | Mouse | |
| Gabrr3 | gamma-aminobutyric acid (GABA) receptor, rho 3 | 0.015 | ||
| Aldh9a1 | aldehyde dehydrogenase 9 family, member A1 | 0.015 | ||
| Gstk1 | glutathione S-transferase kappa 1 | 0.015 | ||
| Nfix | nuclear factor I/X (CCAAT-binding transcription factor) | 0.015 | ||
| Agtr1b | angiotensin II receptor, type 1b | 0.014 | ||
| Hist1h2ba | histone cluster 1, H2ba | 0.014 | ||
| Oxtr | oxytocin receptor | 0.014 | ||
| Asb9 | ankyrin repeat and SOCS box-containing 9 | 0.014 | ||
| Mgst2 | microsomal glutathione S-transferase 2 | 0.014 | ||
| Eci2 | enoyl-Coenzyme A delta isomerase 2 | 0.014 | ||
| Ptgfrn | prostaglandin F2 receptor negative regulator | 0.014 | ||
| Itih4 | inter alpha-trypsin inhibitor, heavy chain 4 | 0.014 | ||
| Gp5 | glycoprotein V (platelet) | 0.013 | ||
| Slc16a8 | solute carrier family 16, member 8 (monocarboxylic acid transporter 3) | 0.013 | ||
| Sult1c2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.013 | ||
| Cpa1 | carboxypeptidase A1 | 0.013 | ||
| Bckdhb | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.013 | ||
| Gpx2 | glutathione peroxidase 2 | 0.013 | ||
| Hao2 | hydroxyacid oxidase 2 (long chain) | 0.013 | ||
| Nlrp6 | NLR family, pyrin domain containing 6 | 0.013 | ||
| Slc44a1 | solute carrier family 44, member 1 | 0.013 | ||
| Ptp4a2 | protein tyrosine phosphatase 4a2 | 0.013 | ||
| Chrnb3 | cholinergic receptor, nicotinic, beta 3 | 0.013 | ||
| Mgst1 | microsomal glutathione S-transferase 1 | 0.013 | ||
| Nfib | nuclear factor I/B | 0.013 | ||
| Ugt2b | UDP glycosyltransferase 2 family, polypeptide B | 0.013 | ||
| Gjb5 | gap junction protein, beta 5 | 0.013 | ||
| Slc2a13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.013 | ||
| Il17f | interleukin 17F | 0.013 | ||
| Hoxb7 | homeo box B7 | 0.012 | ||
| Kcnh1 | potassium voltage-gated channel, subfamily H (eag-related), member 1 | 0.012 | ||
| Htr1d | 5-hydroxytryptamine (serotonin) receptor 1D | 0.012 | ||
| Apoa2 | apolipoprotein A-II | 0.012 | ||
| Slc44a4 | solute carrier family 44, member 4 | 0.012 | ||
| Dmrta1 | DMRT-like family A1 | 0.012 | ||
| Pth2r | parathyroid hormone 2 receptor | 0.012 | ||
| LOC690206 | hypothetical protein LOC690206 | 0.012 | ||
| Hcrtr2 | hypocretin (orexin) receptor 2 | 0.012 | ||
| Vcsa2 | variable coding sequence A2 | 0.012 | ||
| Slc9a3 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 0.012 | ||
| Psgb1 | pregnancy-specific beta 1-glycoprotein | 0.012 | ||
| Thbd | thrombomodulin | 0.012 | ||
| Sfrp4 | secreted frizzled-related protein 4 | 0.012 | ||
| Cdh16 | cadherin 16 | 0.012 | ||
| Elk3 | ELK3, ETS-domain protein | 0.012 | ||
| Sftpd | surfactant protein D | 0.012 | ||
| Gpr150 | G protein-coupled receptor 150 | 0.012 | ||
| Slc38a5 | solute carrier family 38, member 5 | 0.012 | ||
| Pdia4 | protein disulfide isomerase family A, member 4 | 0.011 | ||
| Cd80 | Cd80 molecule | 0.011 | ||
| Il13 | interleukin 13 | 0.011 | ||
| Slc4a1 | solute carrier family 4 (anion exchanger), member 1 | 0.011 | ||
| LOC293989 | cytochrome P450-like | 0.011 | ||
| Hsd17b11 | hydroxysteroid (17-beta) dehydrogenase 11 | 0.011 | ||
| Ppp3r2 | protein phosphatase 3, regulatory subunit B, beta isoform | 0.011 | ||
| S100vp | S100 calcium-binding protein, ventral prostate | 0.011 | ||
| Kcnj4 | potassium inwardly-rectifying channel, subfamily J, member 4 | 0.011 | ||
| Cyp2c22 | cytochrome P450, family 2, subfamily c, polypeptide 22 | 0.011 | ||
| Foxi2 | forkhead box I2 | 0.011 | ||
| Muc4 | mucin 4, cell surface associated | 0.011 | ||
| Mcpt3 | mast cell peptidase 3 | 0.011 | ||
| Fap | fibroblast activation protein, alpha | 0.011 | ||
| Cd40lg | CD40 ligand | 0.011 | ||
| Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.011 | ||
| Sstr3 | somatostatin receptor 3 | 0.011 | ||
| Nudt8 | nudix (nucleoside diphosphate linked moiety X)-type motif 8 | 0.010 | ||
| Cuzd1 | CUB and zona pellucida-like domains 1 | 0.010 | ||
| Gstm2 | glutathione S-transferase mu 2 | 0.010 | ||
| Csn3 | casein kappa | 0.010 | ||
| Kcne1 | potassium voltage-gated channel, Isk-related family, member 1 | 0.010 | ||
| Grid1 | glutamate receptor, ionotropic, delta 1 | 0.010 | ||
| Acadvl | acyl-Coenzyme A dehydrogenase, very long chain | 0.010 | ||
| Slc30a2 | solute carrier family 30 (zinc transporter), member 2 | 0.010 | ||
| Gpc3 | glypican 3 | 0.010 | ||
| Kdr | kinase insert domain receptor | 0.010 | ||
| Pyy | peptide YY (mapped) | 0.010 | ||
| Ccnd2 | cyclin D2 | 0.010 | Rat |