IMP: Integrative Multi-species Prediction

Rattus norvegicus

3 genes annotated in rat

Multi-species View

t cell tolerance induction

GO:0002517

A process involving any mechanism for tolerance induction in T cells.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "t cell tolerance induction"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "t cell tolerance induction" (in gray)

Name	Description	Probability	Func Analog Organism
RT1-EC2	RT1 class Ib, locus EC2	1.000
RT1-S3	RT1 class Ib, locus S3	0.703	Rat
Oas1a	2'-5' oligoadenylate synthetase 1A	0.691
RT1-CE12	RT1 class I, locus CE12	0.629
LOC100364500	RT1 class I, locus CE11-like	0.608
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.535
B2m	beta-2 microglobulin	0.354
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.268
Dock8	dedicator of cytokinesis 8	0.240
RT1-M3-1	RT1 class Ib, locus M3, gene 1	0.209	Rat
Cybb	cytochrome b-245, beta polypeptide	0.185
Ifi35	interferon-induced protein 35	0.152
RT1-N3	RT1 class Ib, locus N3	0.137	Rat
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.130
Cd4	Cd4 molecule	0.125
Yy1	YY1 transcription factor	0.120
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.115
Apol3	apolipoprotein L, 3	0.111
Hnf4a	hepatocyte nuclear factor 4, alpha	0.110
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.101
Cxcl9	chemokine (C-X-C motif) ligand 9	0.101
Fcgr3a	Fc fragment of IgG, low affinity IIIa, receptor	0.097
Cd38	CD38 molecule	0.092
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.091
Capn5	calpain 5	0.086
Fgfr2	fibroblast growth factor receptor 2	0.085
RT1-CE5	RT1 class I, locus CE5	0.081	Rat
Calcrl	calcitonin receptor-like	0.080
Casp1	caspase 1	0.079
LOC246267	resection-induced TPI (rs11)	0.078
Mmp12	matrix metallopeptidase 12	0.077
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.077
Ifi27	interferon, alpha-inducible protein 27	0.076
Il1r1	interleukin 1 receptor, type I	0.072
RT1-Cl	RT1 class Ib, locus Cl	0.070
Mx1	myxovirus (influenza virus) resistance 1	0.067
Cxcl10	chemokine (C-X-C motif) ligand 10	0.061
RT1-A3	RT1 class I, locus A3	0.061
Tas1r3	taste receptor, type 1, member 3	0.060
Met	met proto-oncogene	0.056
Ctsh	cathepsin H	0.054
RGD1305793	similar to hypothetical protein FLJ20154	0.051
Man2b1	mannosidase, alpha, class 2B, member 1	0.049
Rtp4	receptor (chemosensory) transporter protein 4	0.048
Irf7	interferon regulatory factor 7	0.046
Mpeg1	macrophage expressed 1	0.046
Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	0.046
Ahr	aryl hydrocarbon receptor	0.046
Irf1	interferon regulatory factor 1	0.045
Pld1	phospholipase D1	0.042
LOC100364352	cytochrome P450, family 2, subfamily b, polypeptide 9-like	0.040
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.039
Gbp2	guanylate binding protein 2	0.039
Foxc2	forkhead box C2	0.039
Tgfbr2	transforming growth factor, beta receptor II	0.038	Mouse
Ephx1	epoxide hydrolase 1, microsomal	0.037
Lck	lymphocyte-specific protein tyrosine kinase	0.037
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.037
Il7	interleukin 7	0.037
Cyba	cytochrome b-245, alpha polypeptide	0.037
Lgals5	lectin, galactose binding, soluble 5	0.037
Adora3	adenosine A3 receptor	0.036
Aif1	allograft inflammatory factor 1	0.035
Lgals9	lectin, galactoside-binding, soluble, 9	0.035
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.034
Ccl5	chemokine (C-C motif) ligand 5	0.034
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.033
Anpep	alanyl (membrane) aminopeptidase	0.033
Ocln	occludin	0.033
Ptch1	patched homolog 1 (Drosophila)	0.032
Ugt1a7c	UDP glucuronosyltransferase 1 family, polypeptide A7C	0.032
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.031
Tbxa2r	thromboxane A2 receptor	0.031
Cst8	cystatin 8 (cystatin-related epididymal specific)	0.031
Dnase1l3	deoxyribonuclease 1-like 3	0.031
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.031
Olr1082	olfactory receptor 1082	0.030
C2	complement component 2	0.030
Ednra	endothelin receptor type A	0.030
Myo1a	myosin IA	0.030
Bmp6	bone morphogenetic protein 6	0.029
Akr1c14	aldo-keto reductase family 1, member C14	0.029
Tapbp	TAP binding protein	0.029
Galm	galactose mutarotase (aldose 1-epimerase)	0.029
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.028
Cd247	Cd247 molecule	0.028
Olr837	olfactory receptor 837	0.028
Gpr116	G protein-coupled receptor 116	0.028
P2ry12	purinergic receptor P2Y, G-protein coupled, 12	0.027
Olr1346	olfactory receptor 1346	0.027
Gbp5	guanylate binding protein 5	0.027
Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1	0.027
RT1-M6-2	RT1 class I, locus M6, gene 2	0.027	Rat
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.026
Stat6	signal transducer and activator of transcription 6	0.026
Lifr	leukemia inhibitory factor receptor alpha	0.026
Elf1	E74-like factor 1	0.025
Gstm2	glutathione S-transferase mu 2	0.025
RT1-CE2	RT1 class I, locus CE2	0.025	Rat
Mr1	major histocompatibility complex, class I-related	0.024	Rat
RGD1559588	similar to cell surface receptor FDFACT	0.023
Casp8	caspase 8	0.023
Plg	plasminogen	0.023
Dnah11	dynein, axonemal, heavy chain 11	0.023
Bst2	bone marrow stromal cell antigen 2	0.022
Socs3	suppressor of cytokine signaling 3	0.022
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.022
RT1-CE4	RT1 class I, locus CE4	0.022	Rat
Itgb5	integrin, beta 5	0.022
RT1-CE15	RT1 class I, locus CE15	0.021
RT1-CE16	RT1 class I, locus CE16	0.021
Pth	parathyroid hormone	0.021
Il2rb	interleukin 2 receptor, beta	0.021
Cd37	CD37 molecule	0.021
Zbp1	Z-DNA binding protein 1	0.021
Arnt	aryl hydrocarbon receptor nuclear translocator	0.021
LOC100364485	mCG1051031-like	0.020
Col4a3	collagen, type IV, alpha 3	0.020
Rab27a	RAB27A, member RAS oncogene family	0.020
Plbd2	phospholipase B domain containing 2	0.020
Esr2	estrogen receptor 2 (ER beta)	0.020
Ly6b	lymphocyte antigen 6 complex, locus B	0.020
Kynu	kynureninase (L-kynurenine hydrolase)	0.020
RT1-Ba	RT1 class II, locus Ba	0.020
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.020
C3ar1	complement component 3a receptor 1	0.020
Cxcr3	chemokine (C-X-C motif) receptor 3	0.020
Fgf5	fibroblast growth factor 5	0.019
Prf1	perforin 1 (pore forming protein)	0.019
LOC64038	sertolin	0.019
Smad6	SMAD family member 6	0.019
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.019
Hpgds	hematopoietic prostaglandin D synthase	0.019
Mical3	microtubule associated monoxygenase, calponin and LIM domain containing 3	0.019
Prrx1	paired related homeobox 1	0.019
Tcrb	T-cell receptor beta chain	0.019
Nkg7	natural killer cell group 7 sequence	0.019
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.018
Il8ra	interleukin 8 receptor, alpha	0.018
RT1-CE1	RT1 class I, locus1	0.018	Rat
Trim47	tripartite motif-containing 47	0.018
Mrgprx3	MAS-related GPR, member X3	0.018
Cd200r1	CD200 receptor 1	0.018
Hfe	hemochromatosis	0.018	Rat
Nfat5	nuclear factor of activated T-cells 5	0.018
Cga	glycoprotein hormones, alpha polypeptide	0.018
Pde6h	phosphodiesterase 6H, cGMP-specific, cone, gamma	0.017
Il18bp	interleukin 18 binding protein	0.017
Crybg3	beta-gamma crystallin domain containing 3	0.017
Parp3	poly (ADP-ribose) polymerase family, member 3	0.017
Mosc2	MOCO sulphurase C-terminal domain containing 2	0.017
Hyal2	hyaluronoglucosaminidase 2	0.017
Ccr2	chemokine (C-C motif) receptor 2	0.017
Irf8	interferon regulatory factor 8	0.016
Dnah8	dynein, axonemal, heavy chain 8	0.016
Slco2a1	solute carrier organic anion transporter family, member 2a1	0.016
Rab20	RAB20, member RAS oncogene family	0.016
Nmi	N-myc (and STAT) interactor	0.016
Gpr65	G-protein coupled receptor 65	0.016
Cyp2f4	cytochrome P450, family 2, subfamily f, polypeptide 4	0.016
Slc22a18	solute carrier family 22, member 18	0.016
Sult2a1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.016
Chek2	CHK2 checkpoint homolog (S. pombe)	0.016
Foxo3	forkhead box O3	0.015
Gimap8	GTPase, IMAP family member 8	0.015
Shc3	SHC (Src homology 2 domain containing) transforming protein 3	0.015
Phactr2	phosphatase and actin regulator 2	0.015
Ciita	class II, major histocompatibility complex, transactivator	0.015
Spi1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.015
Egr3	early growth response 3	0.015
Neurl3	neuralized homolog 3 (Drosophila)	0.015
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.015
Mllt4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.015
Stap1	signal transducing adaptor family member 1	0.015
RT1-T24-1	RT1 class I, locus T24, gene 1	0.015	Rat
Ptgfr	prostaglandin F receptor	0.015
Hes2	hairy and enhancer of split 2 (Drosophila)	0.015
LOC688090	similar to RT1 class II histocompatibility antigen, B-1 beta chain precursor (RT1.B-beta(1))	0.014
Fcgrt	Fc fragment of IgG, receptor, transporter, alpha	0.014	Rat
Tmem176b	transmembrane protein 176B	0.014
Mgat1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	0.014
Prcp	prolylcarboxypeptidase (angiotensinase C)	0.014
Pcdhga11	protocadherin gamma subfamily A, 11	0.014
Leprot	leptin receptor overlapping transcript	0.014
Sod3	superoxide dismutase 3, extracellular	0.014
B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	0.014
Tfec	transcription factor EC	0.014
Hes3	hairy and enhancer of split 3 (Drosophila)	0.014
Cyp2b12	cytochrome P450, family 2, subfamily b, polypeptide 12	0.014
Gpx3	glutathione peroxidase 3	0.014
Cd8a	CD8a molecule	0.014
Nras	neuroblastoma ras oncogene	0.014
RGD1306526	hypothetical LOC310764	0.013
Fgf2	fibroblast growth factor 2	0.013
Otc	ornithine carbamoyltransferase	0.013
F9	coagulation factor IX	0.013
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.013
Dnah9	dynein, axonemal, heavy polypeptide 9	0.013
Ttc30a1	tetratricopeptide repeat domain 30A1	0.013
Olr226	olfactory receptor 226	0.013
Grin2d	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.013
Prkch	protein kinase C, eta	0.013
Prokr1	prokineticin receptor 1	0.013
Cd93	CD93 molecule	0.013
Tgfbr3	transforming growth factor, beta receptor III	0.013
Apob	apolipoprotein B	0.013
Mc3r	melanocortin 3 receptor	0.013
Fgf1	fibroblast growth factor 1	0.013
Gas2l3	growth arrest-specific 2 like 3	0.013
Impdh1	IMP (inosine monophosphate) dehydrogenase 1	0.013
Igtp	interferon gamma induced GTPase	0.013
Rps6kb2	ribosomal protein S6 kinase, polypeptide 2	0.013
Rhag	Rh-associated glycoprotein	0.013
Izumo1	izumo sperm-egg fusion 1	0.013
Uba7	ubiquitin-like modifier activating enzyme 7	0.012
Nf1	neurofibromin 1	0.012
RGD1559575	similar to novel protein	0.012
Pla2g7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.012
RT1-CE10	RT1 class I, locus CE10	0.012	Rat
Lsm6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.012
Crygc	crystallin, gamma C	0.012
Mycbp2	MYC binding protein 2	0.012
Gimap9	GTPase, IMAP family member 9	0.012
Artn	artemin	0.012
Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	0.012
Itga6	integrin, alpha 6	0.012
Padi1	peptidyl arginine deiminase, type I	0.012
Fam163a	family with sequence similarity 163, member A	0.012
Apcs	amyloid P component, serum	0.012
LOC680711	hypothetical protein LOC680711	0.012
Akap8	A kinase (PRKA) anchor protein 8	0.012
Vom2r53	vomeronasal 2 receptor, 53	0.012
Gpr182	G protein-coupled receptor 182	0.012
Raet1e	retinoic acid early transcript 1E	0.012
Tas2r136	taste receptor, type 2, member 136	0.012
Ubd	ubiquitin D	0.012
Insl3	insulin-like 3	0.012
Cd8b	CD8b molecule	0.012
Dmrt1	doublesex and mab-3 related transcription factor 1	0.012
Col10a1	collagen, type X, alpha 1	0.012
Tnfsf13b	tumor necrosis factor (ligand) superfamily, member 13b	0.012
Pctp	phosphatidylcholine transfer protein	0.012
Olr1557	olfactory receptor 1557	0.012
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.012
B9d2	B9 protein domain 2	0.012
Jrkl	jerky homolog-like (mouse)	0.011
RT1-A1	RT1 class Ia, locus A1	0.011
Atp8b4	ATPase, class I, type 8B, member 4	0.011
Tmtc1	transmembrane and tetratricopeptide repeat containing 1	0.011
Tmem184a	transmembrane protein 184A	0.011
Olr1362	olfactory receptor 1362	0.011
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.011
Hist1h1d	histone cluster 1, H1d	0.011
Was	Wiskott-Aldrich syndrome homolog (human)	0.011
Mgrn1	mahogunin, ring finger 1	0.011
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.011
Tbc1d20	TBC1 domain family, member 20	0.011
Rnf144a	ring finger protein 144A	0.011
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.011
Chrnb3	cholinergic receptor, nicotinic, beta 3	0.011
RGD1562091	similar to expressed sequence C79127	0.011
Plekho2	pleckstrin homology domain containing, family O member 2	0.011
Cradd	CASP2 and RIPK1 domain containing adaptor with death domain	0.011
Yes1	Yamaguchi sarcoma viral (v-yes) oncogene homolog 1	0.011
Cd40lg	CD40 ligand	0.011
Lhb	luteinizing hormone beta	0.011
LOC678704	hypothetical protein LOC678704	0.011
Klri1	killer cell lectin-like receptor family I member 1	0.011
Cyth4	cytohesin 4	0.011
Scn11a	sodium channel, voltage-gated, type XI, alpha	0.011
Cd300lf	CD300 molecule-like family member f	0.011
LOC56764	dnaj-like protein	0.011
Igh-6	immunoglobulin heavy chain 6	0.011
Prokr2	prokineticin receptor 2	0.011
Tmem86a	transmembrane protein 86A	0.011
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.011
Ilvbl	ilvB (bacterial acetolactate synthase)-like	0.011
Spred1	sprouty-related, EVH1 domain containing 1	0.011
Bcl2	B-cell CLL/lymphoma 2	0.011
Inmt	indolethylamine N-methyltransferase	0.011
Phldb3	pleckstrin homology-like domain, family B, member 3	0.011
RT1-CE3	RT1 class I, locus CE3	0.011	Rat
Plcg2	phospholipase C, gamma 2	0.011
Naip2	NLR family, apoptosis inhibitory protein 2	0.011
Rai2	retinoic acid induced 2	0.011
Sec14l3	SEC14-like 3 (S. cerevisiae)	0.011
Gna13	guanine nucleotide binding protein (G protein), alpha 13	0.011
Ly49si1	immunoreceptor Ly49si1	0.011
Nox4	NADPH oxidase 4	0.010
Loh12cr1	loss of heterozygosity, 12, chromosomal region 1 homolog (human)	0.010
Zbtb42	zinc finger and BTB domain containing 42	0.010
Adamts14	ADAM metallopeptidase with thrombospondin type 1 motif, 14	0.010
Olr37	olfactory receptor 37	0.010
Yap1	yes-associated protein 1	0.010
Tmem189	transmembrane protein 189	0.010
Mid1	midline 1	0.010
Pdgfd	platelet-derived growth factor, D polypeptide	0.010
Grhl2	grainyhead-like 2 (Drosophila)	0.010
Slc29a1	solute carrier family 29 (nucleoside transporters), member 1	0.010
Ccdc42b	coiled-coil domain containing 42B	0.010
Sardh	sarcosine dehydrogenase	0.010
Adh1	alcohol dehydrogenase 1 (class I)	0.010
Dse	dermatan sulfate epimerase	0.010
Hk3	hexokinase 3 (white cell)	0.010
Rnf38	ring finger protein 38	0.010
Ikbkg	inhibitor of kappaB kinase gamma	0.010
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.010
Fam172a	family with sequence similarity 172, member A	0.010
LOC100365904	hypothetical protein LOC100365904	0.010
Fam26f	family with sequence similarity 26, member F	0.010
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.010
Btbd4	BTB (POZ) domain containing 4	0.010
Trim47l	tripartite motif protein 47-like	0.010