IMP: Integrative Multi-species Prediction

Rattus norvegicus

2 genes annotated in rat

Multi-species View

defense response to gram positive bacterium

GO:0050830

Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "defense response to gram positive bacterium"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "defense response to gram positive bacterium" (in gray)

Name	Description	Probability	Func Analog Organism
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.089	Mouse
Il1b	interleukin 1 beta	0.078
Ly86	lymphocyte antigen 86	0.055
Ptprc	protein tyrosine phosphatase, receptor type, C	0.052
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.045
Stat2	signal transducer and activator of transcription 2	0.044
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.042
Neurl3	neuralized homolog 3 (Drosophila)	0.039
Reg3a	regenerating islet-derived 3 alpha	0.036
Reg3b	regenerating islet-derived 3 beta	0.035	Mouse
Dock8	dedicator of cytokinesis 8	0.035
Il1a	interleukin 1 alpha	0.034
Calcb	calcitonin-related polypeptide, beta	0.033
Casp1	caspase 1	0.032
Xdh	xanthine dehydrogenase	0.031
Cd40	CD40 molecule, TNF receptor superfamily member 5	0.030
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.030
Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.030
Slfn2	schlafen 2	0.029
Ubd	ubiquitin D	0.029
Rnf213	ring finger protein 213	0.029
Gsg1l	GSG1-like	0.029
Il1r2	interleukin 1 receptor, type II	0.027
Syk	spleen tyrosine kinase	0.027
Cnr2	cannabinoid receptor 2 (macrophage)	0.026
Igsf6	immunoglobulin superfamily, member 6	0.026
Mmp8	matrix metallopeptidase 8	0.025
Rplp2	ribosomal protein, large P2	0.024
Serpinb1a	serine (or cysteine) proteinase inhibitor, clade B, member 1a	0.023
Mocos	molybdenum cofactor sulfurase	0.023
Ccl3	chemokine (C-C motif) ligand 3	0.023
Irak3	interleukin-1 receptor-associated kinase 3	0.022
Acsl1	acyl-CoA synthetase long-chain family member 1	0.022
Zyx	zyxin	0.022
Krt20	keratin 20	0.022
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.021
Cfp	complement factor properdin	0.021
Vav1	vav 1 guanine nucleotide exchange factor	0.021
Il2rg	interleukin 2 receptor, gamma	0.021
Lilrb3l	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like	0.021
Cfi	complement factor I	0.021
Unc13d	unc-13 homolog D (C. elegans)	0.020
G6pc	glucose-6-phosphatase, catalytic subunit	0.020
Aqp7	aquaporin 7	0.020
Gstm3	glutathione S-transferase mu 3	0.020
Ccl20	chemokine (C-C motif) ligand 20	0.020
Prf1	perforin 1 (pore forming protein)	0.020
Mgp	matrix Gla protein	0.020
Odf3	outer dense fiber of sperm tails 3	0.020
Ccl4	chemokine (C-C motif) ligand 4	0.019
Nkg7	natural killer cell group 7 sequence	0.019
Sh2b3	SH2B adaptor protein 3	0.019
Paqr5	progestin and adipoQ receptor family member V	0.019
Mx1	myxovirus (influenza virus) resistance 1	0.019
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.019
Slc28a2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2	0.019
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.019
Il18bp	interleukin 18 binding protein	0.018
Rpgrip1	retinitis pigmentosa GTPase regulator interacting protein 1	0.018
RT1-Db1	RT1 class II, locus Db1	0.018
Tlr2	toll-like receptor 2	0.018
RT1-A3	RT1 class I, locus A3	0.018
LOC686326	similar to Interferon-alpha/beta receptor beta chain precursor (IFN-alpha-REC) (Type I interferon receptor) (IFN-R) (Interferon alpha/beta receptor-2)	0.018
Clec9a	C-type lectin domain family 9, member a	0.018
RGD1562552	similar to hypothetical protein LOC340061	0.018
Il18	interleukin 18	0.018
Havcr1	hepatitis A virus cellular receptor 1	0.018
Pycard	PYD and CARD domain containing	0.018
Slc24a6	solute carrier family 24 (sodium/potassium/calcium exchanger), member 6	0.018
Pxn	paxillin	0.018
Nkx2-4	NK2 homeobox 4	0.017
Cryba4	crystallin, beta A4	0.017
Gpx2	glutathione peroxidase 2	0.017
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.017
Scn10a	sodium channel, voltage-gated, type X, alpha subunit	0.017
LOC100366216	nuclear antigen Sp100-like	0.017
Cd2	Cd2 molecule	0.017
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.017
Aif1	allograft inflammatory factor 1	0.017
siat7D	alpha-2,6-sialyltransferase ST6GalNAc IV	0.017
Apoa5	apolipoprotein A-V	0.017
Mmp12	matrix metallopeptidase 12	0.017
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.017
C5ar1	complement component 5a receptor 1	0.017
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.016
Mov10	Moloney leukemia virus 10	0.016
Adra1a	adrenergic, alpha-1A-, receptor	0.016
Vtcn1	V-set domain containing T cell activation inhibitor 1	0.016
Cxcl13	chemokine (C-X-C motif) ligand 13	0.016
Slc15a3	solute carrier family 15, member 3	0.016
Pdk4	pyruvate dehydrogenase kinase, isozyme 4	0.016
Dhdpsl	dihydrodipicolinate synthase-like, mitochondrial	0.016
Zbtb4	zinc finger and BTB domain containing 4	0.016
Pate4	prostate and testis expressed 4	0.016
Cdh17	cadherin 17	0.015
Mcoln2	mucolipin 2	0.015
Itgb7	integrin, beta 7	0.015
Csn1s1	casein alpha s1	0.015
Olah	oleoyl-ACP hydrolase	0.015
Tgm1	transglutaminase 1, K polypeptide	0.015
Ms4a11	membrane-spanning 4-domains, subfamily A, member 11	0.015
Steap4	STEAP family member 4	0.015
Rasgrp4	RAS guanyl releasing protein 4	0.015
Fcnb	ficolin B	0.015
Fcgr3a	Fc fragment of IgG, low affinity IIIa, receptor	0.015
RGD1305793	similar to hypothetical protein FLJ20154	0.015
Glipr1	GLI pathogenesis-related 1	0.015
Cela2a	chymotrypsin-like elastase family, member 2A	0.015
RT1-Ba	RT1 class II, locus Ba	0.015
Ormdl3	ORM1-like 3 (S. cerevisiae)	0.015
Tas2r123	taste receptor, type 2, member 123	0.015
Cd86	CD86 molecule	0.015
Ltbr	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.015
Il7	interleukin 7	0.014
Tssk2	testis-specific serine kinase 2	0.014
Rt1.aa	MHC class I RT1.Aa alpha-chain	0.014
Nfe2	nuclear factor, erythroid derived 2	0.014
Slpi	secretory leukocyte peptidase inhibitor	0.014
Mospd4	motile sperm domain containing 4	0.014
Ucp1	uncoupling protein 1 (mitochondrial, proton carrier)	0.014
Mca32	mast cell antigen 32	0.014
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.014
Clca4	chloride channel accessory 4	0.014
Cx3cr1	chemokine (C-X3-C motif) receptor 1	0.014
Arhgap25	Rho GTPase activating protein 25	0.014
Oas1a	2'-5' oligoadenylate synthetase 1A	0.014
Cmah	cytidine monophosphate-N-acetylneuraminic acid hydroxylase	0.014
Hcls1	hematopoietic cell specific Lyn substrate 1	0.014
Map3k11	mitogen-activated protein kinase kinase kinase 11	0.014
Rac2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.014
Mmp9	matrix metallopeptidase 9	0.014
Il10	interleukin 10	0.014
Cfd	complement factor D (adipsin)	0.014
Gna15	guanine nucleotide binding protein, alpha 15	0.014
Gabrp	gamma-aminobutyric acid (GABA-A) receptor, pi	0.014
Pik3ip1	phosphoinositide-3-kinase interacting protein 1	0.014
Inpp5d	inositol polyphosphate-5-phosphatase D	0.013
Stat3	signal transducer and activator of transcription 3	0.013
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.013
Trim25	tripartite motif-containing 25	0.013
Slfn3	schlafen 3	0.013
Gch1	GTP cyclohydrolase 1	0.013
Plek	pleckstrin	0.013
Arl11	ADP-ribosylation factor-like 11	0.013
Parvg	parvin, gamma	0.013
Cp	ceruloplasmin	0.013
Faslg	Fas ligand (TNF superfamily, member 6)	0.013
LOC100361879	ATP synthase subunit epsilon, mitochondrial-like	0.013
Tg	thyroglobulin	0.013
RGD1310262	hypothetical LOC304650	0.013
Lrrc26	leucine rich repeat containing 26	0.013
Jak1	Janus kinase 1	0.013
RT1-DMb	RT1 class II, locus DMb	0.013
Lcn2	lipocalin 2	0.013
Adamts7	ADAM metallopeptidase with thrombospondin type 1 motif, 7	0.013
Rab19	RAB19, member RAS oncogene family	0.013
Scarf1	scavenger receptor class F, member 1	0.013
Trim21	tripartite motif-containing 21	0.013
Krt31	keratin 31	0.013
C4bpa	complement component 4 binding protein, alpha	0.013
Retnla	resistin like alpha	0.013
Mafa	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.013
Fchsd1	FCH and double SH3 domains 1	0.013
Hoxb13	homeo box B13	0.013
Txnip	thioredoxin interacting protein	0.013
Rup2	urinary protein 2	0.012
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.012
Krt34	keratin 34	0.012
Cort	cortistatin	0.012
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.012
Vom1r101	vomeronasal 1 receptor 101	0.012
Hand1	heart and neural crest derivatives expressed 1	0.012
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.012
S100a8	S100 calcium binding protein A8	0.012
Cd37	CD37 molecule	0.012
Raf1	v-raf-leukemia viral oncogene 1	0.012
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.012
Spt1	salivary protein 1	0.012
Scn11a	sodium channel, voltage-gated, type XI, alpha	0.012
Tlr7	toll-like receptor 7	0.012
Cela1	chymotrypsin-like elastase family, member 1	0.012
Klk10	kallikrein related-peptidase 10	0.012
Il12rb1	interleukin 12 receptor, beta 1	0.012
Cyp2a3	cytochrome P450, family 2, subfamily a, polypeptide 3	0.012
Plekhn1	pleckstrin homology domain containing, family N member 1	0.012
Chrnd	cholinergic receptor, nicotinic, delta	0.012
Dennd3	DENN/MADD domain containing 3	0.012
Cyp7b1	cytochrome P450, family 7, subfamily b, polypeptide 1	0.012
Gpr4	G protein-coupled receptor 4	0.012
Ncf4	neutrophil cytosolic factor 4	0.012
Csn3	casein kappa	0.012
Psgb1	pregnancy-specific beta 1-glycoprotein	0.012
Dio1	deiodinase, iodothyronine, type I	0.012
Cxcl3	chemokine (C-X-C motif) ligand 3	0.012
RGD1306625	LOC360508	0.012
Cfb	complement factor B	0.012
RGD1561343	similar to C20orf118	0.012
Guca2a	guanylate cyclase activator 2a (guanylin)	0.012
LOC100364796	rCG57268-like	0.012
Limd1	LIM domains containing 1	0.012
Vegfa	vascular endothelial growth factor A	0.012
Grpr	gastrin releasing peptide receptor	0.012
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.012
Ptprh	protein tyrosine phosphatase, receptor type, H	0.012
Fam25a	family with sequence similarity 25, member A	0.011
Tgm3	transglutaminase 3, E polypeptide	0.011
Lrp10	low-density lipoprotein receptor-related protein 10	0.011
Myo1f	myosin IF	0.011
Tp53i13	tumor protein p53 inducible protein 13	0.011
Lama3	laminin, alpha 3	0.011
Tmem82	transmembrane protein 82	0.011
Lpo	lactoperoxidase	0.011
Lrp1	low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)	0.011
Batf	basic leucine zipper transcription factor, ATF-like	0.011
Il7r	interleukin 7 receptor	0.011
Gzmc	granzyme C	0.011
Sla	src-like adaptor	0.011
Klrb1a	killer cell lectin-like receptor subfamily B, member 1A	0.011
LOC363331	similar to plasma membrane associated protein, S3-12	0.011
LOC100360169	rCG21044-like	0.011
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.011
RT1-A2	RT1 class Ia, locus A2	0.011
Sdc4	syndecan 4	0.011
Fkbp2	FK506 binding protein 2	0.011
Bin2	bridging integrator 2	0.011
Ccl22	chemokine (C-C motif) ligand 22	0.011
Bpil3	bactericidal/permeability-increasing protein-like 3	0.011
Dok3	docking protein 3	0.011
Krt1	keratin 1	0.011
Zg16	zymogen granule protein 16	0.011
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.011
Setdb1	SET domain, bifurcated 1	0.011
Krt13	keratin 13	0.011
Tfe3	transcription factor binding to IGHM enhancer 3	0.011
Cmtm6	CKLF-like MARVEL transmembrane domain containing 6	0.011
Setl1	SET translocation-like 1	0.011
Ptafr	platelet-activating factor receptor	0.011
Ly6c	Ly6-C antigen	0.011
Olr1496	olfactory receptor 1496	0.011
Tmprss8	transmembrane protease, serine 8 (intestinal)	0.011
P2rx4	purinergic receptor P2X, ligand-gated ion channel 4	0.011
Il17ra	interleukin 17 receptor A	0.011
Pkn3	protein kinase N3	0.011
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.011
Cwf19l2	CWF19-like 2, cell cycle control (S. pombe)	0.011
S100a9	S100 calcium binding protein A9	0.011
Nhsl2	NHS-like 2	0.011
Gpx4	glutathione peroxidase 4	0.011
LOC100364485	mCG1051031-like	0.011
Cd79b	Cd79b molecule, immunoglobulin-associated beta	0.011
Ntn1	netrin 1	0.011
Lst1	leukocyte specific transcript 1	0.011
Slfn8	schlafen 8	0.011
LOC679475	hypothetical protein LOC679475	0.011
Klrc2	killer cell lectin-like receptor subfamily C, member 2	0.011
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.011
Il6	interleukin 6	0.011
Gbp2	guanylate binding protein 2	0.011
Nlrp6	NLR family, pyrin domain containing 6	0.011
Slc21a4	kidney specific organic anion transporter	0.011
Wnt1	wingless-type MMTV integration site family, member 1	0.011
Rnase2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.011	Human
Ciz1	CDKN1A interacting zinc finger protein 1	0.011
Spp1	secreted phosphoprotein 1	0.011
Yipf7	Yip1 domain family, member 7	0.011
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.011
Nmur1	neuromedin U receptor 1	0.010
Lamb2	laminin, beta 2	0.010
Tbc1d2b	TBC1 domain family, member 2B	0.010
Wnt10a	wingless-type MMTV integration site family, member 10A	0.010
Rad21	RAD21 homolog (S. pombe)	0.010
Whamm	WAS protein homolog associated with actin, golgi membranes and microtubules	0.010
RT1-DOb	RT1 class II, locus DOb	0.010
Riok1	RIO kinase 1 (yeast)	0.010
Trpv6	transient receptor potential cation channel, subfamily V, member 6	0.010
Fam115c	family with sequence similarity 115, member C	0.010
Hrh1	histamine receptor H 1	0.010
Rgl2	ral guanine nucleotide dissociation stimulator-like 2	0.010
LOC100364212	heterogeneous nuclear ribonucleoprotein K-like	0.010
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.010
Gif	gastric intrinsic factor	0.010
LOC100363469	ribosomal protein S24-like	0.010
Dffb	DNA fragmentation factor, beta polypeptide (caspase-activated DNase)	0.010
LOC500956	hypothetical protein LOC500956	0.010
RGD1559748	similar to Palate lung and nasal carcinoma-like protein precursor (Tongue plunc-like protein)	0.010
RGD1304644	similar to RIKEN cDNA 2310046K01	0.010
Gdf15	growth differentiation factor 15	0.010
Plcb2	phospholipase C, beta 2	0.010
Crtc2	CREB regulated transcription coactivator 2	0.010
Cd200r1	CD200 receptor 1	0.010
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.010
Cdc42se1	CDC42 small effector 1	0.010
Hif3a	hypoxia inducible factor 3, alpha subunit	0.010
Krt24	keratin 24	0.010
Hspb9	heat shock protein, alpha-crystallin-related, B9	0.010
Csf1	colony stimulating factor 1 (macrophage)	0.010
Kif6	kinesin family member 6	0.010
Cela3b	chymotrypsin-like elastase family, member 3B	0.010
RGD1562127	similar to chromosome 11 open reading frame 9	0.010
LOC100360843	ribosomal protein S19-like	0.010
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.010
Phemx	pan hematopoietic expression	0.010
Cdcp1	CUB domain containing protein 1	0.010
Fcer2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.010
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.010
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.010
Doxl1	diamine oxidase-like protein 1	0.010
Fgf7	fibroblast growth factor 7	0.010
Adam17	ADAM metallopeptidase domain 17	0.010
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.010
Tessp5	testis serine protease 5	0.010
Herc6	hect domain and RLD 6	0.010