IMP
Process View
negative regulation of lyase activity
Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of lyase activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Hrh3 | histamine receptor H3 | 0.140 | ||
| Scn10a | sodium channel, voltage-gated, type X, alpha subunit | 0.101 | ||
| Calcr | calcitonin receptor | 0.100 | ||
| Cacna1i | calcium channel, voltage-dependent, T type, alpha 1I subunit | 0.096 | ||
| Chrna4 | cholinergic receptor, nicotinic, alpha 4 | 0.074 | ||
| Bcan | brevican | 0.061 | ||
| Syn1 | synapsin I | 0.061 | ||
| Prph2 | peripherin 2 | 0.059 | ||
| Gpr83 | G protein-coupled receptor 83 | 0.053 | ||
| Aqp2 | aquaporin 2 (collecting duct) | 0.048 | ||
| Kcnj4 | potassium inwardly-rectifying channel, subfamily J, member 4 | 0.038 | ||
| Htr4 | 5-hydroxytryptamine (serotonin) receptor 4 | 0.035 | ||
| Slc16a8 | solute carrier family 16, member 8 (monocarboxylic acid transporter 3) | 0.034 | ||
| Cbx6 | chromobox homolog 6 | 0.032 | ||
| Map6 | microtubule-associated protein 6 | 0.027 | ||
| Clcn1 | chloride channel 1 | 0.027 | ||
| Htr7 | 5-hydroxytryptamine (serotonin) receptor 7 | 0.026 | ||
| Amn | amnionless homolog (mouse) | 0.025 | ||
| Olr416 | olfactory receptor 416 | 0.025 | ||
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.024 | ||
| Kcnc2 | potassium voltage gated channel, Shaw-related subfamily, member 2 | 0.023 | ||
| Shank1 | SH3 and multiple ankyrin repeat domains 1 | 0.022 | ||
| Grip2 | glutamate receptor interacting protein 2 | 0.022 | ||
| Sstr1 | somatostatin receptor 1 | 0.021 | ||
| Olr1361 | olfactory receptor 1361 | 0.021 | ||
| Ccr3 | chemokine (C-C motif) receptor 3 | 0.021 | ||
| Gad1 | glutamate decarboxylase 1 | 0.020 | ||
| Kcnb2 | potassium voltage gated channel, Shab-related subfamily, member 2 | 0.020 | ||
| Htr2c | 5-hydroxytryptamine (serotonin) receptor 2C | 0.020 | ||
| Mr1 | major histocompatibility complex, class I-related | 0.019 | ||
| Slc8a2 | solute carrier family 8 (sodium/calcium exchanger), member 2 | 0.018 | ||
| Avpr1b | arginine vasopressin receptor 1B | 0.018 | ||
| Sp3 | Sp3 transcription factor | 0.018 | ||
| Fgf17 | fibroblast growth factor 17 | 0.018 | ||
| Clstn3 | calsyntenin 3 | 0.018 | ||
| Arnt2 | aryl hydrocarbon receptor nuclear translocator 2 | 0.018 | ||
| Tulp1 | tubby like protein 1 | 0.017 | ||
| Gjb5 | gap junction protein, beta 5 | 0.016 | ||
| Oprl1 | opiate receptor-like 1 | 0.016 | Rat | |
| Chrna3 | cholinergic receptor, nicotinic, alpha 3 | 0.016 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.016 | ||
| Tacr1 | tachykinin receptor 1 | 0.015 | ||
| Cort | cortistatin | 0.015 | ||
| Ccr4 | chemokine (C-C motif) receptor 4 | 0.015 | ||
| Htr6 | 5-hydroxytryptamine (serotonin) receptor 6 | 0.014 | ||
| Cd4 | Cd4 molecule | 0.014 | ||
| Nrg1 | neuregulin 1 | 0.014 | ||
| Fgf14 | fibroblast growth factor 14 | 0.014 | ||
| Odf4 | outer dense fiber of sperm tails 4 | 0.014 | ||
| Lif | leukemia inhibitory factor | 0.014 | ||
| Cacna1d | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.013 | ||
| Il9r | interleukin 9 receptor | 0.013 | ||
| Faim2 | Fas apoptotic inhibitory molecule 2 | 0.013 | ||
| Adra2c | adrenergic, alpha-2C-, receptor | 0.012 | ||
| Grm1 | glutamate receptor, metabotropic 1 | 0.012 | ||
| Grp | gastrin releasing peptide | 0.012 | ||
| Acap2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.012 | ||
| Lrp3 | low density lipoprotein receptor-related protein 3 | 0.012 | ||
| Prl | prolactin | 0.011 | ||
| Syn3 | synapsin III | 0.011 | ||
| Apba2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | 0.011 | ||
| Sstr2 | somatostatin receptor 2 | 0.011 | Rat | |
| Barhl2 | BarH-like homeobox 2 | 0.011 | ||
| Foxo3 | forkhead box O3 | 0.011 | ||
| Th | tyrosine hydroxylase | 0.010 | ||
| Chrna6 | cholinergic receptor, nicotinic, alpha 6 | 0.010 | ||
| Chrm3 | cholinergic receptor, muscarinic 3 | 0.010 |