Process View
Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "gap junction assembly"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
Itgb1 | integrin, beta 1 | 0.382 | ||
Fermt2 | fermitin family homolog 2 (Drosophila) | 0.200 | ||
Iqgap1 | IQ motif containing GTPase activating protein 1 | 0.186 | ||
Fam120a | family with sequence similarity 120A | 0.180 | ||
Slc44a1 | solute carrier family 44, member 1 | 0.176 | ||
Fat1 | FAT tumor suppressor homolog 1 (Drosophila) | 0.174 | ||
Cd151 | CD151 molecule (Raph blood group) | 0.160 | ||
Myo1e | myosin IE | 0.154 | ||
Vcl | vinculin | 0.129 | Rat | |
Ctnna1 | catenin (cadherin associated protein), alpha 1 | 0.083 | ||
Sdcbp | syndecan binding protein | 0.073 | ||
Sft2d2 | SFT2 domain containing 2 | 0.064 | ||
Tjp2 | tight junction protein 2 | 0.056 | ||
Lamc1 | laminin, gamma 1 | 0.055 | ||
Macf1 | microtubule-actin crosslinking factor 1 | 0.054 | ||
Ahnak | AHNAK nucleoprotein | 0.054 | ||
Ubb | ubiquitin B | 0.051 | ||
Cltc | clathrin, heavy chain (Hc) | 0.050 | ||
Dync1li2 | dynein, cytoplasmic 1 light intermediate chain 2 | 0.043 | ||
Anxa5 | annexin A5 | 0.040 | ||
Arnt2 | aryl hydrocarbon receptor nuclear translocator 2 | 0.038 | ||
Prkca | protein kinase C, alpha | 0.038 | ||
Fyco1 | FYVE and coiled-coil domain containing 1 | 0.037 | ||
Olr1469 | olfactory receptor Olr1469 | 0.035 | ||
Lzts2 | leucine zipper, putative tumor suppressor 2 | 0.034 | ||
Tjp1 | tight junction protein 1 | 0.033 | ||
St5 | suppression of tumorigenicity 5 | 0.030 | ||
Hmgn1 | high-mobility group nucleosome binding domain 1 | 0.028 | ||
Magi2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.027 | ||
Fgfr4 | fibroblast growth factor receptor 4 | 0.027 | ||
Sptbn2 | spectrin, beta, non-erythrocytic 2 | 0.027 | ||
Zfp426l | zinc finger protein 426-like | 0.027 | ||
Ptpn21 | protein tyrosine phosphatase, non-receptor type 21 | 0.026 | ||
Dsp | desmoplakin | 0.026 | ||
Mtus1 | mitochondrial tumor suppressor 1 | 0.026 | ||
Gnal | guanine nucleotide binding protein, alpha stimulating, olfactory type | 0.023 | ||
Fdxr | ferredoxin reductase | 0.022 | ||
Dock8 | dedicator of cytokinesis 8 | 0.022 | ||
Muc4 | mucin 4, cell surface associated | 0.022 | ||
LOC689074 | similar to Protein KIAA1543 | 0.022 | ||
Irf6 | interferon regulatory factor 6 | 0.021 | ||
Cobll1 | Cobl-like 1 | 0.021 | ||
Cttnbp2 | cortactin binding protein 2 | 0.021 | ||
Tmem98 | transmembrane protein 98 | 0.021 | ||
Dock1 | dedicator of cyto-kinesis 1 | 0.020 | ||
Mylk | myosin light chain kinase | 0.020 | ||
Cgnl1 | cingulin-like 1 | 0.020 | ||
Gata2 | GATA binding protein 2 | 0.020 | ||
Srd5a1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.018 | ||
Furin | furin (paired basic amino acid cleaving enzyme) | 0.018 | ||
Wdr60 | WD repeat domain 60 | 0.017 | ||
Lats2 | large tumor suppressor 2 | 0.017 | ||
Bbs2 | Bardet-Biedl syndrome 2 | 0.017 | ||
Laptm4b | lysosomal protein transmembrane 4 beta | 0.017 | ||
Phtf2 | putative homeodomain transcription factor 2 | 0.017 | ||
Ano6 | anoctamin 6 | 0.017 | ||
Gpr56 | G protein-coupled receptor 56 | 0.017 | ||
Nsd1 | nuclear receptor binding SET domain protein 1 | 0.016 | ||
LOC683626 | similar to limb-bud and heart | 0.016 | ||
Abcc6 | ATP-binding cassette, subfamily C (CFTR/MRP), member 6 | 0.016 | ||
Slmap | sarcolemma associated protein | 0.016 | ||
Rreb1 | ras responsive element binding protein 1 | 0.016 | ||
Ckmt1 | creatine kinase, mitochondrial 1 | 0.016 | ||
Pcaf | p300/CBP-associated factor | 0.015 | ||
Lrrc26 | leucine rich repeat containing 26 | 0.015 | ||
Colq | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase | 0.015 | ||
Pcdh1 | protocadherin 1 | 0.015 | ||
Sox13 | SRY (sex determining region Y)-box 13 | 0.015 | ||
Ptprn2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.014 | ||
RGD1309374 | LOC361485 | 0.014 | ||
Sh3d19 | SH3 domain containing 19 | 0.014 | ||
Dock7 | dedicator of cytokinesis 7 | 0.014 | ||
Fzd6 | frizzled homolog 6 (Drosophila) | 0.014 | ||
Col4a2 | collagen, type IV, alpha 2 | 0.014 | ||
Pls1 | plastin 1 (I isoform) | 0.014 | ||
Ly6al | lymphocyte antigen 6 complex, locus A-like | 0.014 | ||
Myh11 | myosin, heavy chain 11, smooth muscle | 0.013 | ||
Hyal2 | hyaluronoglucosaminidase 2 | 0.013 | ||
Fam70b | family with sequence similarity 70, member B | 0.013 | ||
Pcsk9 | proprotein convertase subtilisin/kexin type 9 | 0.013 | ||
Stat3 | signal transducer and activator of transcription 3 | 0.013 | ||
Nfib | nuclear factor I/B | 0.013 | ||
Ehd4 | EH-domain containing 4 | 0.013 | ||
Gab1 | GRB2-associated binding protein 1 | 0.013 | ||
Pak3 | p21 protein (Cdc42/Rac)-activated kinase 3 | 0.013 | ||
RGD1562885 | similar to RIKEN cDNA 2300002M23 | 0.013 | ||
Clca5 | chloride channel calcium activated 5 | 0.013 | ||
F11r | F11 receptor | 0.013 | ||
Ppp2cb | protein phosphatase 2, catalytic subunit, beta isoform | 0.012 | ||
Rnase1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.012 | ||
RGD1565043 | similar to Rho guanine nucleotide exchange factor (GEF) 10 | 0.012 | ||
Ralgds | ral guanine nucleotide dissociation stimulator | 0.012 | ||
Mier1 | mesoderm induction early response 1 homolog (Xenopus laevis) | 0.012 | ||
Myl9 | myosin, light chain 9, regulatory | 0.012 | ||
Ucp2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.012 | ||
Arhgap21 | Rho GTPase activating protein 21 | 0.012 | ||
Foxd4 | forkhead box D4 | 0.012 | ||
Sec31a | SEC31 homolog A (S. cerevisiae) | 0.011 | ||
Fam83h | family with sequence similarity 83, member H | 0.011 | ||
Dact1 | dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) | 0.011 | ||
Snap25 | synaptosomal-associated protein 25 | 0.011 | ||
Rassf7 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 | 0.011 | ||
Amotl2 | angiomotin like 2 | 0.011 | ||
Ctnnd1 | catenin (cadherin associated protein), delta 1 | 0.011 | Rat | |
Nccrp1 | non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) | 0.011 | ||
Rassf3 | Ras association (RalGDS/AF-6) domain family member 3 | 0.011 | ||
Gdpd2 | glycerophosphodiester phosphodiesterase domain containing 2 | 0.011 | ||
Lrch4 | leucine-rich repeats and calponin homology (CH) domain containing 4 | 0.011 | ||
Sectm1b | secreted and transmembrane 1B | 0.011 | ||
LOC682469 | similar to jumonji domain containing 1B | 0.011 | ||
Rbpms | RNA binding protein with multiple splicing | 0.010 | ||
Stxbp3 | syntaxin binding protein 3 | 0.010 | ||
Ttc7 | tetratricopeptide repeat domain 7 | 0.010 | ||
Creb3l3 | cAMP responsive element binding protein 3-like 3 | 0.010 |