IMP: Integrative Multi-species Prediction

Rattus norvegicus

15 genes annotated in rat

response to mercury ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to mercury ion"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "response to mercury ion" (in gray)

Name	Description	Probability	Func Analog Organism
Mgst1	microsomal glutathione S-transferase 1	0.257
COX2	COXII	0.149
Cyp2d2	cytochrome P450, family 2, subfamily d, polypeptide 2	0.127
Fgg	fibrinogen gamma chain	0.107
Cyp2c11	cytochrome P450, subfamily 2, polypeptide 11	0.095
Apob	apolipoprotein B	0.093
Gnmt	glycine N-methyltransferase	0.084
Cyp3a18	cytochrome P450, family 3, subfamily a, polypeptide 18	0.068	Fly
Otc	ornithine carbamoyltransferase	0.065
Aqp8	aquaporin 8	0.063
Ephx1	epoxide hydrolase 1, microsomal	0.059
Akr1c18	aldo-keto reductase family 1, member C18	0.056
Cps1	carbamoyl-phosphate synthetase 1	0.054
Aldob	aldolase B, fructose-bisphosphate	0.053
Alb	albumin	0.050
Ubb	ubiquitin B	0.049
Apoh	apolipoprotein H (beta-2-glycoprotein I)	0.048
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.047
Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	0.047
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.046
Gstm1	glutathione S-transferase mu 1	0.046
Sult2a2	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2	0.045
Gsta5	glutathione S-transferase Yc2 subunit	0.045	Rat
LOC293989	cytochrome P450-like	0.044
Kynu	kynureninase (L-kynurenine hydrolase)	0.043
Serpina1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.042
Abcb11	ATP-binding cassette, subfamily B (MDR/TAP), member 11	0.039
Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	0.038
Tmem205	transmembrane protein 205	0.037
LOC100361571	keratin associated protein 1-3-like	0.037
Acaa1b	acetyl-Coenzyme A acyltransferase 1B	0.036
Pigr	polymeric immunoglobulin receptor	0.034
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.032
Ugt2b37	UDP-glucuronosyltransferase 2 family, member 37	0.032
Ddt	D-dopachrome tautomerase	0.031
Sult1e1	sulfotransferase family 1E, estrogen-preferring, member 1	0.031
Oaz1	ornithine decarboxylase antizyme 1	0.030
Cyp2c22	cytochrome P450, family 2, subfamily c, polypeptide 22	0.030
Haao	3-hydroxyanthranilate 3,4-dioxygenase	0.029
Cyp3a9	cytochrome P450, family 3, subfamily a, polypeptide 9	0.029	Fly
Mgst2	microsomal glutathione S-transferase 2	0.028
Hpx	hemopexin	0.027
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.027
Tst	thiosulfate sulfurtransferase	0.026
Ndfip1	Nedd4 family interacting protein 1	0.026
Actg1	actin, gamma 1	0.026
Ckm	creatine kinase, muscle	0.026
Mobp	myelin-associated oligodendrocyte basic protein	0.026
Actb	actin, beta	0.025
Sult2al1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1	0.025
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.025
Hcrtr2	hypocretin (orexin) receptor 2	0.025
Gsta2	glutathione S-transferase A2	0.024	Rat
Gstp1	glutathione S-transferase pi 1	0.024
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.023	Rat
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.023
Urod	uroporphyrinogen decarboxylase	0.023
Car2	carbonic anhydrase II	0.023
Azgp1	alpha-2-glycoprotein 1, zinc-binding	0.022
LOC301124	hypothetical LOC301124	0.022
Dhfr	dihydrofolate reductase	0.022
LOC100361547	Cytochrome P450, family 2, subfamily c, polypeptide 7-like	0.022
Ppp3r2	protein phosphatase 3, regulatory subunit B, beta isoform	0.022
Ces1f	carboxylesterase 1F	0.022
Gc	group specific component	0.022	Rat
ND2	NADH dehydrogenase subunit 2	0.021
Cyp2a2	cytochrome P450, family 2, subfamily a, polypeptide 2	0.021
Pah	phenylalanine hydroxylase	0.021
Serpini2	serine (or cysteine) peptidase inhibitor, clade I, member 2	0.021
Klk6	kallikrein related-peptidase 6	0.021
Akr7a3	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)	0.021
Fga	fibrinogen alpha chain	0.021
Gsta3	glutathione S-transferase A3	0.021	Rat
Spp2	secreted phosphoprotein 2	0.021
Klkb1	kallikrein B, plasma 1	0.020
G6pc	glucose-6-phosphatase, catalytic subunit	0.020
Mcpt3	mast cell peptidase 3	0.020
Kap	kidney androgen regulated protein	0.020
Rhag	Rh-associated glycoprotein	0.020
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.020
Tmem59	transmembrane protein 59	0.019
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.019
Prdx2	peroxiredoxin 2	0.019
Prtfdc1	phosphoribosyl transferase domain containing 1	0.019
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.019
Rup2	urinary protein 2	0.019
Gjb3	gap junction protein, beta 3	0.019
Sfrp4	secreted frizzled-related protein 4	0.018
Nqo1	NAD(P)H dehydrogenase, quinone 1	0.018
Hbg1	hemoglobin, gamma A	0.018
Afm	afamin	0.018	Rat
Cyp2b3	cytochrome P450, family 2, subfamily b, polypeptide 3	0.017
Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1	0.017
Apod	apolipoprotein D	0.016
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.016
Acsm3	acyl-CoA synthetase medium-chain family member 3	0.016
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.016
Tmem27	transmembrane protein 27	0.016
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.016
Cyp2c12	cytochrome P450, family 2, subfamily c, polypeptide 12	0.016
Rgn	regucalcin (senescence marker protein-30)	0.016
Smpx	small muscle protein, X-linked	0.016
Wfdc6a	WAP four-disulfide core domain 6A	0.015
Iah1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)	0.015
Apoc1	apolipoprotein C-I	0.015
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.015
Rab7a	RAB7A, member RAS oncogene family	0.015
Pctp	phosphatidylcholine transfer protein	0.015
Plp1	proteolipid protein 1	0.015
Mtmr6	myotubularin related protein 6	0.015
Sult1b1	sulfotransferase family, cytosolic, 1B, member 1	0.015
Si	sucrase-isomaltase (alpha-glucosidase)	0.014
Klk8	kallikrein related-peptidase 8	0.014
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.014
ND1	NADH dehydrogenase subunit 1	0.014
Slco1a4	solute carrier organic anion transporter family, member 1a4	0.014
Hrsp12	heat-responsive protein 12	0.014
RT1-M4	RT1 class Ib, locus M4	0.014
Cyp2c7	cytochrome P450, family 2, subfamily c, polypeptide 7	0.014
Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	0.014
Klrc2	killer cell lectin-like receptor subfamily C, member 2	0.014
Hpd	4-hydroxyphenylpyruvate dioxygenase	0.014
Ftl	ferritin, light polypeptide	0.014
Acaa2	acetyl-Coenzyme A acyltransferase 2	0.014
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.014
Trap1	TNF receptor-associated protein 1	0.013
Kif6	kinesin family member 6	0.013
A1i3	alpha-1-inhibitor III	0.013
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.013
Ahsg	alpha-2-HS-glycoprotein	0.013
Vcsa2	variable coding sequence A2	0.013
Mkrn1	makorin ring finger protein 1	0.013
Ttr	transthyretin	0.013
Cyp2d4	cytochrome P450, family 2, subfamily d, polypeptide 4	0.013
Cyp2b15	cytochrome P450, family 2, subfamily b, polypeptide 15	0.013
Upb1	ureidopropionase, beta	0.013
Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.013
Gjb2	gap junction protein, beta 2	0.013
Lipf	lipase, gastric	0.013
Cd80	Cd80 molecule	0.013
Gsta4	glutathione S-transferase alpha 4	0.013	Rat
Prdx6	peroxiredoxin 6	0.013
Nat1	N-acetyltransferase 1	0.012
Glyat	glycine-N-acyltransferase	0.012
Pzp	pregnancy-zone protein	0.012
Apoa2	apolipoprotein A-II	0.012
Sox30	SRY (sex determining region Y)-box 30	0.012
ATP6	ATPase subunit 6	0.012
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.012
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.012
LOC100365112	carboxylesterase-like	0.012
Cyp3a23/3a1	cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1	0.012	Fly
Gpx4	glutathione peroxidase 4	0.012
Lrrc14b	leucine rich repeat containing 14B	0.012
Ugt1a1	UDP glucuronosyltransferase 1 family, polypeptide A1	0.012
Slco1c1	solute carrier organic anion transporter family, member 1c1	0.012
Serpina4	serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4	0.012
LOC288913	similar to LEYDIG CELL TUMOR 10 KD PROTEIN	0.012
Sord	sorbitol dehydrogenase	0.011
Akr1c12	aldo-keto reductase family 1, member C12	0.011
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.011
Akr7a2	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)	0.011
Amy2	amylase 2, pancreatic	0.011
Hhip	Hedgehog-interacting protein	0.011
Prss1	protease, serine, 1 (trypsin 1)	0.011
Sgk2	serum/glucocorticoid regulated kinase 2	0.011
Igfbp1	insulin-like growth factor binding protein 1	0.011
Pxmp2	peroxisomal membrane protein 2	0.011
Aqp9	aquaporin 9	0.011	Human
Etnk2	ethanolamine kinase 2	0.011
Afp	alpha-fetoprotein	0.011	Rat
Epha8	Eph receptor A8	0.011
Ambp	alpha-1-microglobulin/bikunin precursor	0.011
Ids	iduronate 2-sulfatase	0.011
Fabp1	fatty acid binding protein 1, liver	0.011
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.010	Fly
Ugt2b	UDP glycosyltransferase 2 family, polypeptide B	0.010
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.010
Cd9	CD9 molecule	0.010
Anxa5	annexin A5	0.010
Asb11	ankyrin repeat and SOCS box-containing 11	0.010
Pth2r	parathyroid hormone 2 receptor	0.010
Akr1c1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.010
Hnmt	histamine N-methyltransferase	0.010