Process View
The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "metaphase anaphase transition of mitotic cell cycle"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
Cdca3 | cell division cycle associated 3 | 0.446 | ||
Foxm1 | forkhead box M1 | 0.313 | ||
Top2a | topoisomerase (DNA) II alpha | 0.220 | ||
Ccnb1 | cyclin B1 | 0.184 | ||
Melk | maternal embryonic leucine zipper kinase | 0.164 | ||
Troap | trophinin associated protein | 0.152 | ||
Spc25 | SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.126 | ||
Prc1 | protein regulator of cytokinesis 1 | 0.114 | ||
Spag5 | sperm associated antigen 5 | 0.112 | ||
LOC100310874 | antisense RNA overlapping MCH | 0.087 | ||
Asf1b | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.076 | ||
Pak2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.075 | ||
Cdkn3 | cyclin-dependent kinase inhibitor 3 | 0.066 | ||
LOC689399 | hypothetical protein LOC689399 | 0.063 | ||
Lbr | lamin B receptor | 0.058 | ||
Ppp4r2 | protein phosphatase 4, regulatory subunit 2 | 0.056 | ||
Racgap1 | Rac GTPase-activating protein 1 | 0.055 | ||
Kif20b | kinesin family member 20B | 0.054 | ||
Tpm4 | tropomyosin 4 | 0.053 | ||
Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.048 | ||
Kif2c | kinesin family member 2C | 0.047 | ||
Arih1 | ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) | 0.047 | ||
Ccnb2 | cyclin B2 | 0.047 | ||
Cdk1 | cyclin-dependent kinase 1 | 0.046 | ||
Mcm5 | minichromosome maintenance complex component 5 | 0.045 | ||
Eps15 | epidermal growth factor receptor pathway substrate 15 | 0.044 | ||
Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.043 | Yeast Worm Fly | |
Depdc1 | DEP domain containing 1 | 0.043 | ||
Kif22 | kinesin family member 22 | 0.043 | ||
Wdfy1 | WD repeat and FYVE domain containing 1 | 0.043 | ||
Ccne1 | cyclin E1 | 0.040 | Fly | |
E2f1 | E2F transcription factor 1 | 0.039 | ||
Kifc1 | kinesin family member C1 | 0.038 | ||
Plk1 | polo-like kinase 1 (Drosophila) | 0.038 | Human | |
Ube2t | ubiquitin-conjugating enzyme E2T (putative) | 0.038 | ||
Ect2 | epithelial cell transforming sequence 2 oncogene | 0.038 | ||
Ckap2 | cytoskeleton associated protein 2 | 0.037 | ||
Pbk | PDZ binding kinase | 0.037 | ||
Nusap1 | nucleolar and spindle associated protein 1 | 0.037 | ||
Taok1 | TAO kinase 1 | 0.037 | ||
Depdc1b | DEP domain containing 1B | 0.036 | ||
Tcf4 | transcription factor 4 | 0.036 | ||
Espl1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.035 | ||
Nuf2 | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.034 | ||
Ube2c | ubiquitin-conjugating enzyme E2C | 0.033 | ||
Dlgap5 | discs, large (Drosophila) homolog-associated protein 5 | 0.033 | ||
Clic4 | chloride intracellular channel 4 | 0.032 | ||
Ppm1b | protein phosphatase 1B, magnesium dependent, beta isoform | 0.032 | ||
Cenpi | centromere protein I | 0.031 | ||
Mtr | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.031 | ||
Arfip1 | ADP-ribosylation factor interacting protein 1 | 0.031 | ||
Kif18b | kinesin family member 18B | 0.031 | ||
Cops2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.030 | ||
MGC112830 | similar to transcription factor | 0.030 | ||
Pi4k2b | phosphatidylinositol 4-kinase type 2 beta | 0.029 | ||
Ndrg2 | N-myc downstream regulated gene 2 | 0.028 | ||
Aurkb | aurora kinase B | 0.028 | ||
Uhrf1 | ubiquitin-like with PHD and ring finger domains 1 | 0.027 | ||
Stk17b | serine/threonine kinase 17b | 0.027 | ||
Pkn2 | protein kinase N2 | 0.027 | ||
Ttk | Ttk protein kinase | 0.026 | ||
Ncapd2 | non-SMC condensin I complex, subunit D2 | 0.026 | ||
Myh10 | myosin, heavy chain 10, non-muscle | 0.026 | ||
Prkaca | protein kinase, cAMP-dependent, catalytic, alpha | 0.025 | ||
Ska1 | spindle and kinetochore associated complex subunit 1 | 0.025 | ||
Cenpf | centromere protein F | 0.024 | ||
Traf4af1 | TRAF4 associated factor 1 | 0.024 | ||
Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.024 | ||
Tjp2 | tight junction protein 2 | 0.023 | ||
Ube2h | ubiquitin-conjugating enzyme E2H | 0.023 | ||
Ccna2 | cyclin A2 | 0.023 | ||
Btg1 | B-cell translocation gene 1, anti-proliferative | 0.023 | ||
Myo1b | myosin Ib | 0.023 | ||
Rala | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.023 | ||
Slain2 | SLAIN motif family, member 2 | 0.023 | ||
Wdr26 | WD repeat domain 26 | 0.023 | ||
Bcr | breakpoint cluster region | 0.022 | ||
Cdca2 | cell division cycle associated 2 | 0.022 | ||
Eif2c2 | eukaryotic translation initiation factor 2C, 2 | 0.022 | ||
Litaf | lipopolysaccharide-induced TNF factor | 0.022 | ||
Mbd2 | methyl-CpG binding domain protein 2 | 0.021 | ||
Gmfb | glia maturation factor, beta | 0.021 | ||
Lrch4 | leucine-rich repeats and calponin homology (CH) domain containing 4 | 0.021 | ||
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.021 | ||
Arhgap11a | Rho GTPase activating protein 11A | 0.021 | ||
Traip | TRAF-interacting protein | 0.021 | ||
Atf2 | activating transcription factor 2 | 0.021 | ||
Ctnnd2 | catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) | 0.020 | ||
Taok2 | TAO kinase 2 | 0.020 | ||
RGD1308127 | similar to 2700078E11Rik protein | 0.020 | ||
Ccdc99 | coiled-coil domain containing 99 | 0.020 | ||
Rnf14 | ring finger protein 14 | 0.020 | ||
Top2b | topoisomerase (DNA) II beta | 0.020 | ||
Gna12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.020 | ||
Znf76 | zinc finger protein 76 (expressed in testis) | 0.020 | ||
Appbp2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.020 | ||
Cd82 | Cd82 molecule | 0.020 | ||
Cyth3 | cytohesin 3 | 0.020 | ||
Vapa | VAMP (vesicle-associated membrane protein)-associated protein A | 0.020 | ||
Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.020 | ||
Cdk2 | cyclin dependent kinase 2 | 0.020 | ||
Cenpt | centromere protein T | 0.019 | ||
Rad51c | Rad51 homolog c (S. cerevisiae) | 0.019 | ||
Nr3c2 | nuclear receptor subfamily 3, group C, member 2 | 0.019 | ||
Bard1 | BRCA1 associated RING domain 1 | 0.019 | ||
Gpr19 | G protein-coupled receptor 19 | 0.019 | ||
Man1a1 | mannosidase, alpha, class 1A, member 1 | 0.018 | ||
Tle4 | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 0.018 | ||
Fam63b | family with sequence similarity 63, member B | 0.018 | ||
Efhd2 | EF-hand domain family, member D2 | 0.018 | ||
RT1-DMa | RT1 class II, locus DMa | 0.018 | ||
Grk5 | G protein-coupled receptor kinase 5 | 0.018 | ||
Rab28 | RAB28, member RAS oncogene family | 0.018 | ||
Cenpn | centromere protein N | 0.018 | ||
Pfkfb1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 0.018 | ||
Zfp364 | zinc finger protein 364 | 0.017 | ||
Zfp91 | zinc finger protein 91 | 0.017 | ||
Maoa | monoamine oxidase A | 0.017 | ||
Atp2b1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.017 | ||
Usp9x | ubiquitin specific peptidase 9, X-linked | 0.017 | ||
Ccnf | cyclin F | 0.017 | ||
Aurka | aurora kinase A | 0.017 | ||
Kpna3 | karyopherin alpha 3 | 0.017 | ||
Mxd3 | Max dimerization protein 3 | 0.017 | ||
Haus4 | HAUS augmin-like complex, subunit 4 | 0.017 | ||
Arf6 | ADP-ribosylation factor 6 | 0.017 | ||
Usp12 | ubiquitin specific peptidase 12 | 0.017 | ||
Aspm | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.017 | ||
Cul1 | cullin 1 | 0.017 | ||
Pgam2 | phosphoglycerate mutase 2 (muscle) | 0.017 | ||
Zfp37 | zinc finger protein 37 | 0.017 | ||
Chaf1a | chromatin assembly factor 1, subunit A (p150) | 0.016 | ||
Plk4 | polo-like kinase 4 (Drosophila) | 0.016 | ||
Kif4 | kinesin family member 4 | 0.016 | ||
Atxn2 | ataxin 2 | 0.016 | ||
Myo1c | myosin IC | 0.016 | ||
Adrm1 | adhesion regulating molecule 1 | 0.016 | ||
Mto1 | mitochondrial translation optimization 1 homolog (S. cerevisiae) | 0.016 | ||
Pds5a | PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) | 0.016 | ||
Agfg1 | ArfGAP with FG repeats 1 | 0.016 | ||
Syncrip | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.016 | ||
Pkmyt1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.016 | ||
Map3k7 | mitogen activated protein kinase kinase kinase 7 | 0.016 | ||
Agps | alkylglycerone phosphate synthase | 0.016 | ||
Plekha1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.015 | ||
Tgfbr2 | transforming growth factor, beta receptor II | 0.015 | ||
Cks2 | CDC28 protein kinase regulatory subunit 2 | 0.015 | ||
Cttn | cortactin | 0.015 | ||
Homer1 | homer homolog 1 (Drosophila) | 0.015 | ||
Mmp16 | matrix metallopeptidase 16 | 0.015 | ||
Brca2 | breast cancer 2 | 0.015 | ||
Dhfr | dihydrofolate reductase | 0.015 | ||
Hmmr | hyaluronan mediated motility receptor (RHAMM) | 0.015 | ||
Ppp3ca | protein phosphatase 3, catalytic subunit, alpha isoform | 0.015 | ||
Clcn3 | chloride channel 3 | 0.015 | ||
Dync1li2 | dynein, cytoplasmic 1 light intermediate chain 2 | 0.015 | ||
Pttg1 | pituitary tumor-transforming 1 | 0.015 | ||
Nek9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.015 | ||
Prdm4 | PR domain containing 4 | 0.015 | ||
Rac1 | ras-related C3 botulinum toxin substrate 1 | 0.015 | ||
Rab27a | RAB27A, member RAS oncogene family | 0.015 | ||
Cdca8 | cell division cycle associated 8 | 0.015 | ||
Dlat | dihydrolipoamide S-acetyltransferase | 0.015 | ||
Trip13 | thyroid hormone receptor interactor 13 | 0.015 | ||
Afp | alpha-fetoprotein | 0.015 | ||
Jak2 | Janus kinase 2 | 0.015 | ||
Cebpg | CCAAT/enhancer binding protein (C/EBP), gamma | 0.014 | ||
Gclm | glutamate cysteine ligase, modifier subunit | 0.014 | ||
Rad51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.014 | ||
Mre11a | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.014 | ||
Cd44 | Cd44 molecule | 0.014 | ||
Zhx1 | zinc fingers and homeoboxes 1 | 0.014 | ||
Rgs19 | regulator of G-protein signaling 19 | 0.014 | ||
Vps13b | vacuolar protein sorting 13 homolog B (yeast) | 0.014 | ||
Atp6v0a1 | ATPase, H+ transporting, lysosomal V0 subunit A1 | 0.014 | ||
Ubl3 | ubiquitin-like 3 | 0.014 | ||
Cmya5 | cardiomyopathy associated 5 | 0.014 | ||
Trdmt1 | tRNA aspartic acid methyltransferase 1 | 0.014 | ||
Rnd3 | Rho family GTPase 3 | 0.014 | ||
Dlg1 | discs, large homolog 1 (Drosophila) | 0.014 | ||
Prkaa1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | 0.014 | ||
Zfr | zinc finger RNA binding protein | 0.014 | ||
Wee1 | wee 1 homolog (S. pombe) | 0.014 | ||
Cep78 | centrosomal protein 78 | 0.013 | ||
Ppard | peroxisome proliferator-activated receptor delta | 0.013 | ||
Ttn | titin | 0.013 | ||
Dyrk1a | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.013 | ||
Rad54l | RAD54 like (S. cerevisiae) | 0.013 | ||
Ska3 | spindle and kinetochore associated complex subunit 3 | 0.013 | ||
Gata3 | GATA binding protein 3 | 0.013 | ||
Kcns3 | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 | 0.013 | ||
Pmf1 | polyamine-modulated factor 1 | 0.013 | ||
Tcf12 | transcription factor 12 | 0.013 | ||
Kcnn1 | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 | 0.013 | ||
Dynlt3 | dynein light chain Tctex-type 3 | 0.013 | ||
Sec14l1 | SEC14-like 1 (S. cerevisiae) | 0.013 | ||
Akt3 | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 0.013 | ||
Klk1c10 | T-kininogenase | 0.013 | ||
Ppp1r9a | protein phosphatase 1, regulatory (inhibitor) subunit 9A | 0.013 | ||
Rrm2 | ribonucleotide reductase M2 | 0.013 | ||
Bbx | bobby sox homolog (Drosophila) | 0.013 | ||
Cd24 | CD24 molecule | 0.013 | ||
Lamc1 | laminin, gamma 1 | 0.013 | ||
Exo1 | exonuclease 1 | 0.013 | ||
Dsn1 | DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.013 | ||
Pola2 | polymerase (DNA directed), alpha 2 | 0.012 | ||
Emx2 | empty spiracles homeobox 2 | 0.012 | ||
Nfix | nuclear factor I/X (CCAAT-binding transcription factor) | 0.012 | ||
Pcnx | pecanex homolog (Drosophila) | 0.012 | ||
C1galt1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 | 0.012 | ||
Wbp11 | WW domain binding protein 11 | 0.012 | ||
Pcgf5 | polycomb group ring finger 5 | 0.012 | ||
Klf10 | Kruppel-like factor 10 | 0.012 | ||
Zfp260 | zinc finger protein 260 | 0.012 | ||
Cdh1 | cadherin 1 | 0.012 | ||
Kntc1 | kinetochore associated 1 | 0.012 | ||
Cul3 | cullin 3 | 0.012 | Human | |
RGD1309102 | similar to TRS85 homolog | 0.012 | ||
Ptpru | protein tyrosine phosphatase, receptor type, U | 0.012 | ||
Mybl2 | myeloblastosis oncogene-like 2 | 0.012 | ||
Kif15 | kinesin family member 15 | 0.012 | ||
Bnip2 | BCL2/adenovirus E1B interacting protein 2 | 0.012 | ||
Zfp189 | zinc finger protein 189 | 0.012 | ||
Bag5 | BCL2-associated athanogene 5 | 0.012 | ||
Cenpe | centromere protein E | 0.012 | ||
Gbe1 | glucan (1,4-alpha-), branching enzyme 1 | 0.012 | ||
Slmap | sarcolemma associated protein | 0.012 | ||
Mdm2 | Mdm2 p53 binding protein homolog (mouse) | 0.012 | ||
Xkr5 | XK, Kell blood group complex subunit-related family, member 5 | 0.012 | ||
Stat4 | signal transducer and activator of transcription 4 | 0.012 | ||
Pou2f2 | POU class 2 homeobox 2 | 0.012 | ||
Mobkl1b | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.012 | ||
Bcl2l2 | Bcl2-like 2 | 0.012 | ||
Chek1 | CHK1 checkpoint homolog (S. pombe) | 0.012 | ||
Alx1 | ALX homeobox 1 | 0.012 | ||
Nrgn | neurogranin | 0.012 | ||
Eif5b | eukaryotic translation initiation factor 5B | 0.012 | ||
C1qtnf4 | C1q and tumor necrosis factor related protein 4 | 0.012 | ||
Ccng1 | cyclin G1 | 0.011 | ||
Tmx4 | thioredoxin-related transmembrane protein 4 | 0.011 | ||
Mak | male germ cell-associated kinase | 0.011 | ||
Enpp1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.011 | ||
Dctn4 | dynactin 4 | 0.011 | ||
Usp24 | ubiquitin specific protease 24 | 0.011 | ||
Srd5a1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.011 | ||
Eftud2 | elongation factor Tu GTP binding domain containing 2 | 0.011 | ||
Mtdh | metadherin | 0.011 | ||
Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | 0.011 | ||
Cdc25b | cell division cycle 25 homolog B (S. pombe) | 0.011 | ||
Pgm2l1 | phosphoglucomutase 2-like 1 | 0.011 | ||
Csnk1g3 | casein kinase 1, gamma 3 | 0.011 | ||
Cntnap1 | contactin associated protein 1 | 0.011 | ||
Kcnn3 | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 | 0.011 | ||
Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.011 | ||
Akap11 | A kinase (PRKA) anchor protein 11 | 0.011 | ||
Zmym2 | zinc finger, MYM-type 2 | 0.011 | ||
Klf16 | Kruppel-like factor 16 | 0.011 | ||
Picalm | phosphatidylinositol binding clathrin assembly protein | 0.011 | ||
Sypl1 | synaptophysin-like 1 | 0.011 | ||
MGC95208 | similar to 4930453N24Rik protein | 0.011 | ||
Cdc27 | cell division cycle 27 homolog (S. cerevisiae) | 0.011 | Human | |
Ube2g1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | 0.011 | ||
Timm44 | translocase of inner mitochondrial membrane 44 homolog (yeast) | 0.011 | ||
Pacs1 | phosphofurin acidic cluster sorting protein 1 | 0.011 | ||
Ryk | receptor-like tyrosine kinase | 0.011 | ||
Brca1 | breast cancer 1 | 0.011 | ||
Ptprg | protein tyrosine phosphatase, receptor type, G | 0.011 | ||
Tusc3 | tumor suppressor candidate 3 | 0.011 | ||
Trim63 | tripartite motif-containing 63 | 0.011 | ||
Nat12 | N-acetyltransferase 12 (GCN5-related, putative) | 0.011 | ||
Zswim5 | zinc finger, SWIM domain containing 5 | 0.011 | ||
Basp1 | brain abundant, membrane attached signal protein 1 | 0.011 | ||
Hivep1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.011 | ||
Skiv2l | superkiller viralicidic activity 2-like (S. cerevisiae ) | 0.011 | ||
Prm2 | protamine 2 | 0.011 | ||
Ccdc72 | coiled-coil domain containing 72 | 0.010 | ||
Tyms | thymidylate synthetase | 0.010 | ||
Camsap1l1 | calmodulin regulated spectrin-associated protein 1-like 1 | 0.010 | ||
LOC100174910 | glutaredoxin-like protein | 0.010 | ||
Magi3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.010 | ||
Lrp3 | low density lipoprotein receptor-related protein 3 | 0.010 | ||
Snap29 | synaptosomal-associated protein 29 | 0.010 | ||
Ppif | peptidylprolyl isomerase F | 0.010 | ||
Dnajb5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | 0.010 | ||
Cenpq | centromere protein Q | 0.010 | ||
Sufu | suppressor of fused homolog (Drosophila) | 0.010 | ||
Herc2 | hect domain and RLD 2 | 0.010 | ||
Pold1 | polymerase (DNA directed), delta 1, catalytic subunit | 0.010 | ||
Rapgef5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.010 | ||
Snca | synuclein, alpha (non A4 component of amyloid precursor) | 0.010 | ||
Ager | advanced glycosylation end product-specific receptor | 0.010 | ||
Syngr1 | synaptogyrin 1 | 0.010 | ||
March7 | membrane-associated ring finger (C3HC4) 7 | 0.010 | ||
Gda | guanine deaminase | 0.010 | ||
Sipa1l1 | signal-induced proliferation-associated 1 like 1 | 0.010 | ||
Atp2c1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.010 | ||
Tpp2 | tripeptidyl peptidase II | 0.010 | ||
Mypn | myopalladin | 0.010 | ||
Nedd4l | neural precursor cell expressed, developmentally down-regulated 4-like | 0.010 | ||
Cast | calpastatin | 0.010 | ||
Sptlc2 | serine palmitoyltransferase, long chain base subunit 2 | 0.010 | ||
Gca | grancalcin | 0.010 | ||
Tubgcp2 | tubulin, gamma complex associated protein 2 | 0.010 | ||
Col9a1 | collagen, type IX, alpha 1 | 0.010 | ||
G0s2 | G0/G1switch 2 | 0.010 | ||
Pold3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.010 | ||
Ephb1 | Eph receptor B1 | 0.010 |