IMP
Process View
somatic stem cell maintenance
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "somatic stem cell maintenance"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Nek9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.341 | ||
| Eif2c2 | eukaryotic translation initiation factor 2C, 2 | 0.172 | ||
| Nfix | nuclear factor I/X (CCAAT-binding transcription factor) | 0.098 | ||
| Bbx | bobby sox homolog (Drosophila) | 0.051 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.049 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.046 | ||
| Axin1 | axin 1 | 0.040 | ||
| Adam10 | ADAM metallopeptidase domain 10 | 0.038 | ||
| Zfp91 | zinc finger protein 91 | 0.037 | ||
| Igfbp5 | insulin-like growth factor binding protein 5 | 0.036 | ||
| Ppp1r12a | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 0.035 | ||
| Rara | retinoic acid receptor, alpha | 0.034 | ||
| Mcm5 | minichromosome maintenance complex component 5 | 0.033 | ||
| Nfib | nuclear factor I/B | 0.031 | ||
| Atf2 | activating transcription factor 2 | 0.031 | ||
| Gata3 | GATA binding protein 3 | 0.029 | ||
| Pacs1 | phosphofurin acidic cluster sorting protein 1 | 0.027 | ||
| Acyp2 | acylphosphatase 2, muscle type | 0.027 | ||
| Triobp | TRIO and F-actin binding protein | 0.026 | ||
| Lfng | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.026 | ||
| Cd4 | Cd4 molecule | 0.026 | ||
| Sema6b | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | 0.025 | ||
| Notch1 | Notch homolog 1, translocation-associated (Drosophila) | 0.024 | ||
| Tfeb | transcription factor EB | 0.024 | ||
| Aanat | arylalkylamine N-acetyltransferase | 0.024 | ||
| Abcc1 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 | 0.023 | ||
| Klf13 | Kruppel-like factor 13 | 0.023 | ||
| Twist1 | twist homolog 1 (Drosophila) | 0.022 | ||
| Flt1 | FMS-related tyrosine kinase 1 | 0.022 | ||
| Acvr1 | activin A receptor, type I | 0.021 | ||
| Lig3 | ligase III, DNA, ATP-dependent | 0.021 | ||
| Ccnd2 | cyclin D2 | 0.021 | ||
| Rps6ka1 | ribosomal protein S6 kinase polypeptide 1 | 0.021 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.019 | ||
| Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.019 | ||
| Prkce | protein kinase C, epsilon | 0.019 | ||
| Slc6a6 | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | 0.019 | ||
| Ednrb | endothelin receptor type B | 0.018 | ||
| Foxp4 | forkhead box P4 | 0.018 | ||
| Gna15 | guanine nucleotide binding protein, alpha 15 | 0.018 | ||
| Mtdh | metadherin | 0.017 | ||
| Dlgap4 | discs, large homolog-associated protein 4 (Drosophila) | 0.017 | ||
| Casp2 | caspase 2 | 0.017 | ||
| Itgb4 | integrin, beta 4 | 0.016 | ||
| Itpr2 | inositol 1,4,5-triphosphate receptor, type 2 | 0.016 | ||
| Atp2a3 | ATPase, Ca++ transporting, ubiquitous | 0.016 | ||
| Tcp11l2 | t-complex 11 (mouse) like 2 | 0.016 | ||
| Gsk3b | glycogen synthase kinase 3 beta | 0.016 | Fly | |
| Lbr | lamin B receptor | 0.016 | ||
| Adrm1 | adhesion regulating molecule 1 | 0.016 | ||
| Tcf4 | transcription factor 4 | 0.016 | Fly | |
| Lman1 | lectin, mannose-binding, 1 | 0.016 | ||
| Cdk2 | cyclin dependent kinase 2 | 0.015 | ||
| Cpd | carboxypeptidase D | 0.015 | ||
| Smad7 | SMAD family member 7 | 0.015 | ||
| Sec14l1 | SEC14-like 1 (S. cerevisiae) | 0.015 | ||
| Top2a | topoisomerase (DNA) II alpha | 0.015 | ||
| Rgs19 | regulator of G-protein signaling 19 | 0.015 | ||
| Taok2 | TAO kinase 2 | 0.014 | ||
| Atp1b2 | ATPase, Na+/K+ transporting, beta 2 polypeptide | 0.014 | ||
| Myo1c | myosin IC | 0.014 | ||
| Mapk9 | mitogen-activated protein kinase 9 | 0.014 | ||
| Tceb3 | transcription elongation factor B (SIII), polypeptide 3 | 0.014 | ||
| Npap60 | nuclear pore associated protein | 0.014 | ||
| Nras | neuroblastoma ras oncogene | 0.014 | ||
| Fgf16 | fibroblast growth factor 16 | 0.014 | ||
| Wdfy1 | WD repeat and FYVE domain containing 1 | 0.014 | ||
| Utrn | utrophin | 0.014 | ||
| Lrch4 | leucine-rich repeats and calponin homology (CH) domain containing 4 | 0.014 | ||
| Clic4 | chloride intracellular channel 4 | 0.014 | ||
| Nfia | nuclear factor I/A | 0.014 | ||
| Igf2 | insulin-like growth factor 2 | 0.014 | ||
| Chac2 | ChaC, cation transport regulator homolog 2 (E. coli) | 0.014 | ||
| Slit3 | slit homolog 3 (Drosophila) | 0.014 | ||
| Atp2b1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.013 | ||
| Chad | chondroadherin | 0.013 | ||
| Tpcr12 | putative olfactory receptor | 0.013 | ||
| Pou2f3 | POU class 2 homeobox 3 | 0.013 | ||
| Tob1 | transducer of ErbB-2.1 | 0.013 | ||
| Irs1 | insulin receptor substrate 1 | 0.013 | ||
| Gipc1 | GIPC PDZ domain containing family, member 1 | 0.013 | ||
| Mgll | monoglyceride lipase | 0.013 | ||
| Chd4 | chromodomain helicase DNA binding protein 4 | 0.013 | ||
| Creb3l1 | cAMP responsive element binding protein 3-like 1 | 0.013 | ||
| Creb1 | cAMP responsive element binding protein 1 | 0.013 | ||
| Tspyl1 | TSPY-like 1 | 0.013 | ||
| Rph3al | rabphilin 3A-like (without C2 domains) | 0.013 | ||
| Mllt4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.012 | ||
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.012 | ||
| Mtx2 | metaxin 2 | 0.012 | ||
| Nkx2-1 | NK2 homeobox 1 | 0.012 | ||
| Lep | leptin | 0.012 | ||
| Hdac7 | histone deacetylase 7 | 0.012 | ||
| Kctd15 | potassium channel tetramerisation domain containing 15 | 0.012 | ||
| Gse1 | genetic suppressor element 1 | 0.012 | ||
| Mfsd10 | major facilitator superfamily domain containing 10 | 0.012 | ||
| Cep78 | centrosomal protein 78 | 0.012 | ||
| Rasa1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.012 | ||
| Myo1b | myosin Ib | 0.012 | ||
| Nfic | nuclear factor I/C | 0.012 | ||
| Snap29 | synaptosomal-associated protein 29 | 0.012 | ||
| Efnb1 | ephrin B1 | 0.012 | ||
| Csn3 | casein kappa | 0.012 | ||
| Prkaa2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.012 | ||
| Pdpk1 | 3-phosphoinositide dependent protein kinase-1 | 0.012 | ||
| Rxra | retinoid X receptor alpha | 0.011 | ||
| Cd5 | Cd5 molecule | 0.011 | ||
| Adam22 | a disintegrin and metalloprotease domain (ADAM) 22 | 0.011 | ||
| Npr2 | natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) | 0.011 | ||
| Mocs1 | molybdenum cofactor synthesis 1 | 0.011 | ||
| Rala | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.011 | ||
| Foxo1 | forkhead box O1 | 0.011 | ||
| Ube2h | ubiquitin-conjugating enzyme E2H | 0.011 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.011 | ||
| Fgfr1 | Fibroblast growth factor receptor 1 | 0.011 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.011 | ||
| Eif4g1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.011 | ||
| Gjb4 | gap junction protein, beta 4 | 0.011 | ||
| Cad | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.011 | ||
| Clcn7 | chloride channel 7 | 0.011 | ||
| Ralgds | ral guanine nucleotide dissociation stimulator | 0.011 | ||
| Stx6 | syntaxin 6 | 0.011 | ||
| Prom2 | prominin 2 | 0.011 | ||
| Akt2 | v-akt murine thymoma viral oncogene homolog 2 | 0.011 | ||
| Wbp2 | WW domain binding protein 2 | 0.011 | ||
| Lphn2 | latrophilin 2 | 0.011 | ||
| Sirpa | signal-regulatory protein alpha | 0.011 | ||
| Rasa2 | RAS p21 protein activator 2 | 0.011 | ||
| Bcr | breakpoint cluster region | 0.011 | ||
| Smo | smoothened homolog (Drosophila) | 0.011 | Fly | |
| Foxp1 | forkhead box P1 | 0.010 | ||
| Prdm4 | PR domain containing 4 | 0.010 | ||
| Ttyh3 | tweety homolog 3 (Drosophila) | 0.010 | ||
| Pou2f2 | POU class 2 homeobox 2 | 0.010 | ||
| Aox4 | aldehyde oxidase 4 | 0.010 | ||
| Arrdc1 | arrestin domain containing 1 | 0.010 | ||
| Mll5 | myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila) | 0.010 | ||
| LOC688314 | similar to stimulated by retinoic acid 13 | 0.010 | ||
| Prdm2 | PR domain containing 2, with ZNF domain | 0.010 | ||
| Unc5b | unc-5 homolog B (C. elegans) | 0.010 | ||
| Ccdc8 | coiled-coil domain containing 8 | 0.010 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.010 | ||
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.010 | ||
| Dvl3 | dishevelled, dsh homolog 3 (Drosophila) | 0.010 | ||
| Atxn2 | ataxin 2 | 0.010 | ||
| Pik3r3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.010 |