IMP
Process View
glutathione metabolic process
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "glutathione metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Gstm1 | glutathione S-transferase mu 1 | 1.000 | ||
| Hba-a2 | hemoglobin alpha, adult chain 2 | 0.996 | ||
| Gstp1 | glutathione S-transferase pi 1 | 0.984 | Human Mouse | |
| Hbb | hemoglobin, beta | 0.980 | ||
| Gsta3 | glutathione S-transferase A3 | 0.974 | ||
| LOC100134871 | beta globin minor gene | 0.947 | Rat | |
| Hbb-b1 | hemoglobin, beta adult major chain | 0.938 | Rat | |
| Alas2 | aminolevulinate, delta-, synthase 2 | 0.917 | ||
| Mgst1 | microsomal glutathione S-transferase 1 | 0.888 | Mouse | |
| Ephx1 | epoxide hydrolase 1, microsomal | 0.825 | ||
| LOC287167 | globin, alpha | 0.771 | ||
| Qdpr | quinoid dihydropteridine reductase | 0.616 | ||
| Gstt1 | glutathione S-transferase theta 1 | 0.574 | ||
| LOC689064 | beta-globin | 0.574 | ||
| Ugt1a6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.546 | ||
| Cyb5r3 | cytochrome b5 reductase 3 | 0.418 | ||
| Oaz1 | ornithine decarboxylase antizyme 1 | 0.363 | ||
| Cyb5a | cytochrome b5 type A (microsomal) | 0.331 | ||
| Gclc | glutamate-cysteine ligase, catalytic subunit | 0.296 | ||
| Mgst3 | microsomal glutathione S-transferase 3 | 0.273 | ||
| Gpx4 | glutathione peroxidase 4 | 0.234 | ||
| LOC100363662 | 6-phosphogluconate dehydrogenase, decarboxylating-like | 0.185 | ||
| Gstt2 | glutathione S-transferase, theta 2 | 0.151 | ||
| Gstm2 | glutathione S-transferase mu 2 | 0.144 | Human Rat | |
| Gsta4 | glutathione S-transferase alpha 4 | 0.125 | ||
| Tmem205 | transmembrane protein 205 | 0.119 | ||
| Nqo1 | NAD(P)H dehydrogenase, quinone 1 | 0.119 | ||
| Cyp2d4 | cytochrome P450, family 2, subfamily d, polypeptide 4 | 0.116 | ||
| Akr1b8 | aldo-keto reductase family 1, member B8 | 0.110 | ||
| Selenbp1 | selenium binding protein 1 | 0.101 | ||
| Sod1 | superoxide dismutase 1, soluble | 0.093 | Mouse | |
| Mgst2 | microsomal glutathione S-transferase 2 | 0.089 | Human | |
| Ddt | D-dopachrome tautomerase | 0.075 | ||
| Cat | catalase | 0.069 | ||
| Gsta5 | glutathione S-transferase Yc2 subunit | 0.064 | ||
| Ubqln1 | ubiquilin 1 | 0.060 | ||
| Akr1a1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 0.055 | ||
| S100a1 | S100 calcium binding protein A1 | 0.055 | ||
| Prdx6 | peroxiredoxin 6 | 0.054 | ||
| Gabarapl2 | GABA(A) receptor-associated protein like 2 | 0.053 | ||
| Gstk1 | glutathione S-transferase kappa 1 | 0.044 | ||
| Cst3 | cystatin C | 0.044 | ||
| Gsr | glutathione reductase | 0.041 | ||
| Srxn1 | sulfiredoxin 1 homolog (S. cerevisiae) | 0.040 | ||
| Prdx5 | peroxiredoxin 5 | 0.040 | ||
| Gstm5 | glutathione S-transferase, mu 5 | 0.039 | Human Rat | |
| Hebp1 | heme binding protein 1 | 0.039 | ||
| Akr7a3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.037 | ||
| Pgrmc1 | progesterone receptor membrane component 1 | 0.036 | ||
| Mosc2 | MOCO sulphurase C-terminal domain containing 2 | 0.034 | ||
| Ftl | ferritin, light polypeptide | 0.033 | ||
| Ndufa6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (B14) | 0.030 | ||
| Blvra | biliverdin reductase A | 0.030 | ||
| Ugdh | UDP-glucose dehydrogenase | 0.028 | ||
| Hmox1 | heme oxygenase (decycling) 1 | 0.027 | ||
| Klrc2 | killer cell lectin-like receptor subfamily C, member 2 | 0.027 | ||
| Gstt3 | glutathione S-transferase, theta 3 | 0.027 | Human Rat Fly | |
| Ptgr1 | prostaglandin reductase 1 | 0.026 | ||
| Cyp4f6 | cytochrome P450, family 4, subfamily f, polypeptide 6 | 0.024 | ||
| Lonp2 | lon peptidase 2, peroxisomal | 0.024 | ||
| Hrsp12 | heat-responsive protein 12 | 0.024 | ||
| PVR | poliovirus receptor | 0.023 | ||
| Syngr1 | synaptogyrin 1 | 0.023 | ||
| Acp2 | acid phosphatase 2, lysosomal | 0.022 | ||
| Me1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.022 | ||
| Clu | clusterin | 0.022 | ||
| Aldh1a1 | aldehyde dehydrogenase 1 family, member A1 | 0.020 | ||
| Nsun4 | NOL1/NOP2/Sun domain family, member 4 | 0.020 | ||
| Acads | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 0.020 | ||
| Pir | pirin (iron-binding nuclear protein) | 0.019 | ||
| Tmem120a | transmembrane protein 120A | 0.019 | ||
| Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.019 | ||
| Cyp4f1 | cytochrome P450, family 4, subfamily f, polypeptide 1 | 0.018 | ||
| Pold4 | polymerase (DNA-directed), delta 4 | 0.018 | ||
| Acot1 | acyl-CoA thioesterase 1 | 0.018 | ||
| Txnrd1 | thioredoxin reductase 1 | 0.018 | ||
| Arf6 | ADP-ribosylation factor 6 | 0.018 | ||
| Rnasek | ribonuclease, RNase K | 0.017 | ||
| Hsd17b11 | hydroxysteroid (17-beta) dehydrogenase 11 | 0.017 | ||
| Pcbd1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 0.017 | ||
| Tf | transferrin | 0.017 | ||
| Cyp27a1 | cytochrome P450, family 27, subfamily a, polypeptide 1 | 0.016 | ||
| Sirt3 | sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) | 0.016 | ||
| Cml5 | camello-like 5 | 0.016 | ||
| Bbx | bobby sox homolog (Drosophila) | 0.016 | ||
| Por | P450 (cytochrome) oxidoreductase | 0.015 | ||
| Slc25a39 | solute carrier family 25, member 39 | 0.015 | ||
| Blvrb | biliverdin reductase B (flavin reductase (NADPH)) | 0.015 | ||
| G6pd | glucose-6-phosphate dehydrogenase | 0.015 | Mouse | |
| Cyp2f4 | cytochrome P450, family 2, subfamily f, polypeptide 4 | 0.015 | ||
| Pla2g2a | phospholipase A2, group IIA (platelets, synovial fluid) | 0.015 | ||
| Nln | neurolysin (metallopeptidase M3 family) | 0.015 | ||
| Lipa | lipase A, lysosomal acid, cholesterol esterase | 0.015 | ||
| Nipsnap1 | nipsnap homolog 1 (C. elegans) | 0.014 | ||
| Rnf181 | ring finger protein 181 | 0.014 | ||
| Ly6b | lymphocyte antigen 6 complex, locus B | 0.014 | ||
| Eraf | erythroid associated factor | 0.014 | ||
| Zadh2 | zinc binding alcohol dehydrogenase, domain containing 2 | 0.014 | ||
| Znf394 | zinc finger protein 394 | 0.014 | ||
| Prdx2 | peroxiredoxin 2 | 0.014 | ||
| Hagh | hydroxyacyl glutathione hydrolase | 0.014 | ||
| Cyp3a2 | cytochrome P450, family 3, subfamily a, polypeptide 2 | 0.014 | ||
| Abhd4 | abhydrolase domain containing 4 | 0.013 | ||
| Aldh1l1 | aldehyde dehydrogenase 1 family, member L1 | 0.013 | ||
| Mafk | v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) | 0.013 | ||
| Sult1a1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | 0.013 | ||
| Rbck1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.012 | ||
| Pf4 | platelet factor 4 | 0.012 | ||
| Eps8l2 | EPS8-like 2 | 0.012 | ||
| Stradb | STE20-related kinase adaptor beta | 0.012 | ||
| Osgin1 | oxidative stress induced growth inhibitor 1 | 0.012 | ||
| Sfxn4 | sideroflexin 4 | 0.012 | ||
| Htatip2 | HIV-1 tat interactive protein 2, homolog (human) | 0.012 | ||
| Dnajc12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.011 | ||
| Acox1 | acyl-Coenzyme A oxidase 1, palmitoyl | 0.011 | ||
| Pdp2 | pyruvate dehyrogenase phosphatase catalytic subunit 2 | 0.011 | ||
| Fbp2 | fructose-1,6-bisphosphatase 2 | 0.011 | ||
| Mgmt | O-6-methylguanine-DNA methyltransferase | 0.011 | ||
| RGD1309676 | similar to RIKEN cDNA 5730469M10 | 0.011 | ||
| Krt8 | keratin 8 | 0.011 | ||
| Gss | glutathione synthetase | 0.011 | ||
| LOC100360507 | inducible carbonyl reductase-like | 0.011 | ||
| Fmo1 | flavin containing monooxygenase 1 | 0.011 | ||
| Slc40a1 | solute carrier family 39 (iron-regulated transporter), member 1 | 0.011 | ||
| Gclm | glutamate cysteine ligase, modifier subunit | 0.011 | ||
| Ctdsp1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | 0.011 | ||
| Suclg1 | succinate-CoA ligase, alpha subunit | 0.011 | ||
| Cth | cystathionase (cystathionine gamma-lyase) | 0.011 | ||
| Dtd1 | D-tyrosyl-tRNA deacylase 1 homolog (S. cerevisiae) | 0.010 | ||
| Cox8a | cytochrome c oxidase subunit VIIIa | 0.010 | ||
| LOC681186 | hypothetical protein LOC681186 | 0.010 | ||
| RGD1309779 | similar to ENSANGP00000021391 | 0.010 | ||
| Gdf10 | growth differentiation factor 10 | 0.010 | ||
| Pcyt2 | phosphate cytidylyltransferase 2, ethanolamine | 0.010 | ||
| Asrgl1 | asparaginase like 1 | 0.010 | ||
| Cybrd1 | cytochrome b reductase 1 | 0.010 | ||
| LOC678880 | similar to mammalian retrotransposon derived 8b | 0.010 | ||
| Ddc | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 0.010 |