IMP: Integrative Multi-species Prediction

Rattus norvegicus

3 genes annotated in rat

Multi-species View

sterol homeostasis

GO:0055092

Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "sterol homeostasis"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "sterol homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
Dbp	D site of albumin promoter (albumin D-box) binding protein	0.789
Cfd	complement factor D (adipsin)	0.109
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.087
Hnf4a	hepatocyte nuclear factor 4, alpha	0.077	Mouse
Hnf1b	HNF1 homeobox B	0.077
Apoa5	apolipoprotein A-V	0.075
Sult1b1	sulfotransferase family, cytosolic, 1B, member 1	0.067
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.065
Ppara	peroxisome proliferator activated receptor alpha	0.060
A1cf	APOBEC1 complementation factor	0.053
Trib1	tribbles homolog 1 (Drosophila)	0.052
Abcg8	ATP-binding cassette, subfamily G (WHITE), member 8	0.050
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.048
UST4r	integral membrane transport protein UST4r	0.047
Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	0.047
Cyb5r4	cytochrome b5 reductase 4	0.046
Lpl	lipoprotein lipase	0.046
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.045
Cldn3	claudin 3	0.043
Hrg	histidine-rich glycoprotein	0.041
Hmgcr	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	0.039
Xpnpep2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.039
Acot12	acyl-CoA thioesterase 12	0.039
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.038
Cyp2b3	cytochrome P450, family 2, subfamily b, polypeptide 3	0.036
Slco1b3	solute carrier organic anion transporter family, member 1b3	0.035
Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1	0.035
Unc5cl	unc-5 homolog C (C. elegans)-like	0.035
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.035	Fly
Azgp1	alpha-2-glycoprotein 1, zinc-binding	0.034
Smad6	SMAD family member 6	0.032
A1bg	alpha-1-B glycoprotein	0.031
Fbp1	fructose-1,6-bisphosphatase 1	0.031
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.030
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.029
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.029	Rat
Foxa3	forkhead box A3	0.028
Chuk	conserved helix-loop-helix ubiquitous kinase	0.028
Mettl7b	methyltransferase like 7B	0.027
Lss	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	0.027
Galp	galanin-like peptide	0.027
Abcb11	ATP-binding cassette, subfamily B (MDR/TAP), member 11	0.027
Sec24d	SEC24 family, member D (S. cerevisiae)	0.026
Masp2	mannan-binding lectin serine peptidase 2	0.026
Clcn2	chloride channel 2	0.026
Tcf3	transcription factor 3	0.026
Obp1f	odorant binding protein I f	0.025
Lect2	leukocyte cell-derived chemotaxin 2	0.025
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.025
Hsd17b4	hydroxysteroid (17-beta) dehydrogenase 4	0.025
Sardh	sarcosine dehydrogenase	0.025
Gulo	gulonolactone (L-) oxidase	0.024
Slc13a3	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	0.024
Hfe2	hemochromatosis type 2 (juvenile) homolog (human)	0.024
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.024
G6pc	glucose-6-phosphatase, catalytic subunit	0.023
Serpind1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.023
Olr1466	olfactory receptor 1466	0.023
Serpinc1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.023
Tmem82	transmembrane protein 82	0.022
Cyp2c12	cytochrome P450, family 2, subfamily c, polypeptide 12	0.021
Phf17	PHD finger protein 17	0.021
Gpr182	G protein-coupled receptor 182	0.021
Sec14l2	SEC14-like 2 (S. cerevisiae)	0.021
Serpinf2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.021
Zcchc24	zinc finger, CCHC domain containing 24	0.021
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.021
F10	coagulation factor X	0.021
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.021
Aldh9a1	aldehyde dehydrogenase 9 family, member A1	0.021
Foxa2	forkhead box A2	0.021
Tbc1d15	TBC1 domain family, member 15	0.020
Dmbt1	deleted in malignant brain tumors 1	0.020
Commd10	COMM domain containing 10	0.020
Cps1	carbamoyl-phosphate synthetase 1	0.020
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.020
F2	coagulation factor II (thrombin)	0.020
Ahr	aryl hydrocarbon receptor	0.020
F12	coagulation factor XII (Hageman factor)	0.020
Aco1	aconitase 1, soluble	0.019
Keg1	kidney expressed gene 1	0.019
Fut1	fucosyltransferase 1	0.019
Slc22a23	solute carrier family 22, member 23	0.019
Ammecr1l	AMME chromosomal region gene 1-like	0.019
Sdr42e1	short chain dehydrogenase/reductase family 42E, member 1	0.019
Fasn	fatty acid synthase	0.019
Tyw1	tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)	0.019
Cd36	CD36 molecule (thrombospondin receptor)	0.018
Inhbc	inhibin beta C	0.018
Pon3	paraoxonase 3	0.018
Asgr1	asialoglycoprotein receptor 1	0.018
Abcb4	ATP-binding cassette, subfamily B (MDR/TAP), member 4	0.018
Mbl1	mannose-binding lectin (protein A) 1	0.018
Baat	bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.018
Cela1	chymotrypsin-like elastase family, member 1	0.018
C8b	complement component 8, beta polypeptide	0.018
Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	0.018
Cda	cytidine deaminase	0.018
Rab33b	RAB33B, member of RAS oncogene family	0.018
Nr1d2	nuclear receptor subfamily 1, group D, member 2	0.017
Rt1.aa	MHC class I RT1.Aa alpha-chain	0.017
Rdh2	retinol dehydrogenase 2	0.017
Ntn1	netrin 1	0.017
Gprc5c	G protein-coupled receptor, family C, group 5, member C	0.017
Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	0.017
Ddr1	discoidin domain receptor tyrosine kinase 1	0.017
Amy1a	amylase, alpha 1A (salivary)	0.017
Lama3	laminin, alpha 3	0.017
Slco2a1	solute carrier organic anion transporter family, member 2a1	0.017
Pzp	pregnancy-zone protein	0.017
Hal	histidine ammonia lyase	0.017
Glyat	glycine-N-acyltransferase	0.017
Cyp4v3	cytochrome P450, family 4, subfamily v, polypeptide 3	0.017
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.017
Bmf	Bcl2 modifying factor	0.016
Gstm3	glutathione S-transferase mu 3	0.016
Tmigd1	transmembrane and immunoglobulin domain containing 1	0.016
Cyp51	cytochrome P450, family 51	0.016
Akap5	A kinase (PRKA) anchor protein 5	0.016
Lepr	leptin receptor	0.016
Zbp1	Z-DNA binding protein 1	0.016
Il15	interleukin 15	0.016
Il1r1	interleukin 1 receptor, type I	0.016
Crp	C-reactive protein, pentraxin-related	0.016
Plbd1	phospholipase B domain containing 1	0.016
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.016
Mmgt1	membrane magnesium transporter 1	0.016
Col13a1	collagen, type XIII, alpha 1	0.016
Mst1	Macrophage stimulating 1 (hepatocyte growth factor-like)	0.016
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.016
Gimap7	GTPase, IMAP family member 7	0.016
Fabp1	fatty acid binding protein 1, liver	0.016
Cnnm3	cyclin M3	0.015
Mucdhl	mucin and cadherin like	0.015
Plg	plasminogen	0.015
Akr1b7	aldo-keto reductase family 1, member B7	0.015
Bhmt2	betaine-homocysteine methyltransferase 2	0.015
Lonp2	lon peptidase 2, peroxisomal	0.015
Hgd	homogentisate 1, 2-dioxygenase	0.015
Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	0.015
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.015
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.015
Inhbe	inhibin beta E	0.015
Gfra3	GDNF family receptor alpha 3	0.015
Cyp2d4	cytochrome P450, family 2, subfamily d, polypeptide 4	0.015
Tcf21	transcription factor 21	0.015
Clec4f	C-type lectin domain family 4, member f	0.015
Etv3	ets variant 3	0.015
RGD1305347	similar to RIKEN cDNA 2610528J11	0.015
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.015
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.015
Pex12	peroxisomal biogenesis factor 12	0.015
Sox13	SRY (sex determining region Y)-box 13	0.015
Abcc6	ATP-binding cassette, subfamily C (CFTR/MRP), member 6	0.014
Sts	steroid sulfatase	0.014
Dag1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.014
Hsd17b7	hydroxysteroid (17-beta) dehydrogenase 7	0.014
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.014
Per3	period homolog 3 (Drosophila)	0.014
Sgpl1	sphingosine-1-phosphate lyase 1	0.014
Slc6a13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.014
Svs4	seminal vesicle secretory protein 4	0.014
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.014
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.014
Pcsk9	proprotein convertase subtilisin/kexin type 9	0.014
Cldn6	claudin 6	0.014
Rxra	retinoid X receptor alpha	0.014
Socs6	suppressor of cytokine signaling 6	0.014
Sphk2	sphingosine kinase 2	0.014
Creb3l3	cAMP responsive element binding protein 3-like 3	0.014
Srd5a1	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	0.014
Srebf1	sterol regulatory element binding transcription factor 1	0.014
Ptprk	protein tyrosine phosphatase, receptor type, K, extracellular region	0.014
Prpsap1	phosphoribosyl pyrophosphate synthetase-associated protein 1	0.014
LOC680889	hypothetical protein LOC680889	0.014
Rbp7	retinol binding protein 7, cellular	0.014
Serpina3m	serine (or cysteine) proteinase inhibitor, clade A, member 3M	0.014
Cidea	cell death-inducing DFFA-like effector a	0.013
Cbs	cystathionine beta synthase	0.013
Nfx1	nuclear transcription factor, X-box binding 1	0.013
Sectm1b	secreted and transmembrane 1B	0.013
Fdft1	farnesyl diphosphate farnesyl transferase 1	0.013
Slc25a10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	0.013
Cyp2b1	cytochrome P450, family 2, subfamily b, polypeptide 1	0.013
Cd5l	Cd5 molecule-like	0.013
RGD1566296	similar to RIKEN cDNA B230114P05	0.013
Rorc	RAR-related orphan receptor C	0.013
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.013
Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	0.013
Car5a	carbonic anhydrase 5a, mitochondrial	0.013
Ppy	pancreatic polypeptide	0.013
Tpt1	tumor protein, translationally-controlled 1	0.013
Hnf1a	HNF1 homeobox A	0.013
Slc43a1	solute carrier family 43, member 1	0.013
Glud1	glutamate dehydrogenase 1	0.013
Cpb1	carboxypeptidase B1 (tissue)	0.013
Neu3	sialidase 3 (membrane sialidase)	0.013
Prl8a4	prolactin family 8, subfamily a, member 4	0.013
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.013
Cldn7	claudin 7	0.013
Thrsp	thyroid hormone responsive	0.013
LOC691759	hypothetical protein LOC691759	0.013
Hsd17b6	hydroxysteroid (17-beta) dehydrogenase 6	0.013
Pacsin2	protein kinase C and casein kinase substrate in neurons 2	0.013
Aqp8	aquaporin 8	0.013
RGD1309759	similar to cDNA sequence BC013529	0.012
Mvk	mevalonate kinase	0.012
RGD1562844	similar to serine (or cysteine) proteinase inhibitor, clade B, member 9	0.012
Cyp17a1	cytochrome P450, family 17, subfamily a, polypeptide 1	0.012
Fgl1	fibrinogen-like 1	0.012
Ccl21	chemokine (C-C motif) ligand 21	0.012
Foxa1	forkhead box A1	0.012
Spata2	spermatogenesis associated 2	0.012
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.012
Pkp3	plakophilin 3	0.012
Spg20	spastic paraplegia 20 (Troyer syndrome) homolog (human)	0.012
Rarg	retinoic acid receptor, gamma	0.012
Ces2c	carboxylesterase 2C	0.012
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.012
St5	suppression of tumorigenicity 5	0.012
Spic	Spi-C transcription factor (Spi-1/PU.1 related)	0.012
Cblc	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.012
Adap2	ArfGAP with dual PH domains 2	0.012
Lpgat1	lysophosphatidylglycerol acyltransferase 1	0.012
Fbxo39	F-box protein 39	0.012
Pla2g10	phospholipase A2, group X	0.012
Ahsg	alpha-2-HS-glycoprotein	0.012
Ppp1r15b	protein phosphatase 1, regulatory (inhibitor) subunit 15b	0.012
Aldh3a2	aldehyde dehydrogenase 3 family, member A2	0.012
Gata2	GATA binding protein 2	0.012
Acsl4	acyl-CoA synthetase long-chain family member 4	0.012
LOC680122	similar to sin3 associated polypeptide	0.012
Fbll1	fibrillarin-like 1	0.012
Manba	mannosidase, beta A, lysosomal	0.012
Dhcr24	24-dehydrocholesterol reductase	0.012
Cnr2	cannabinoid receptor 2 (macrophage)	0.012
Insr	insulin receptor	0.012
Agmat	agmatine ureohydrolase (agmatinase)	0.012
C8a	complement component 8, alpha polypeptide	0.012
Gpr146	G protein-coupled receptor 146	0.012
Pou2af1	POU class 2 associating factor 1	0.012
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.012
Caskin2	cask-interacting protein 2	0.012
Dgat2	diacylglycerol O-acyltransferase homolog 2 (mouse)	0.012
Gnpda2	glucosamine-6-phosphate deaminase 2	0.012
Scd1	stearoyl-Coenzyme A desaturase 1	0.012
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.012
Tmem168	transmembrane protein 168	0.012
Plcb2	phospholipase C, beta 2	0.012
Abca1	ATP-binding cassette, subfamily A (ABC1), member 1	0.011
Tmem72	transmembrane protein 72	0.011
Acadvl	acyl-Coenzyme A dehydrogenase, very long chain	0.011
RGD1310495	similar to KIAA1919 protein	0.011
Fez2	fasciculation and elongation protein zeta 2 (zygin II)	0.011
Hsd17b11	hydroxysteroid (17-beta) dehydrogenase 11	0.011
Ubqln3	ubiquilin 3	0.011
Slc2a9	solute carrier family 2 (facilitated glucose transporter), member 9	0.011
Mcpt4	mast cell protease 4	0.011
Sacm1l	SAC1 suppressor of actin mutations 1-like (yeast)	0.011
Mapk6	mitogen-activated protein kinase 6	0.011
LOC689074	similar to Protein KIAA1543	0.011
Si	sucrase-isomaltase (alpha-glucosidase)	0.011
Cyp39a1	cytochrome P450, family 39, subfamily a, polypeptide 1	0.011
Sc4mol	sterol-C4-methyl oxidase-like	0.011
Gif	gastric intrinsic factor	0.011
RGD1309922	similar to 2610301G19Rik protein	0.011
Gstt2	glutathione S-transferase, theta 2	0.011
Tmprss2	transmembrane protease, serine 2	0.011
Scn7a	sodium channel, voltage-gated, type VII, alpha	0.011
Nfe2l1	nuclear factor, erythroid derived 2,-like 1	0.011
Naaladl1	N-acetylated alpha-linked acidic dipeptidase-like 1	0.011
Lrrc14b	leucine rich repeat containing 14B	0.011
Gys2	glycogen synthase 2	0.011
Ints4	integrator complex subunit 4	0.011
Dmgdh	dimethylglycine dehydrogenase	0.011
Colec11	collectin sub-family member 11	0.011
Tspan12	tetraspanin 12	0.011
Nrbf2	nuclear receptor binding factor 2	0.011
Akr1d1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.011
Fgfr4	fibroblast growth factor receptor 4	0.011	Mouse
Serpina11	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11	0.011
Vtn	vitronectin	0.011
Mug1	murinoglobulin 1	0.011
Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	0.011
March8	membrane-associated ring finger (C3HC4) 8	0.011
Siae	sialic acid acetylesterase	0.011
Asmt	acetylserotonin O-methyltransferase	0.011
RGD1562291	similar to Human T-cell leukemia virus enhancer factor (Forkhead box protein N2)	0.011
Vnn1	vanin 1	0.011
Xylb	xylulokinase homolog (H. influenzae)	0.011
Rdh5	retinol dehydrogenase 5	0.011
LOC100361007	rCG32064-like	0.011
Cln3	ceroid-lipofuscinosis, neuronal 3	0.011
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.011
Sema4g	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G	0.011
Hgfac	hepatocyte growth factor activator	0.011
Padi3	peptidyl arginine deiminase, type III	0.011
Nars2	asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)	0.011
Runx2	runt-related transcription factor 2	0.011
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.011
Slc16a10	solute carrier family 16 (monocarboxylic acid transporters), member 10	0.011
Tmprss8	transmembrane protease, serine 8 (intestinal)	0.011
RGD1559600	RGD1559600	0.011
Ttc7	tetratricopeptide repeat domain 7	0.011
Maob	monoamine oxidase B	0.011
Mppe1	metallophosphoesterase 1	0.011
Zbtb43	zinc finger and BTB domain containing 43	0.011
Khk	ketohexokinase	0.011
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.011
Map3k11	mitogen-activated protein kinase kinase kinase 11	0.011
Sigirr	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	0.011
Golt1a	golgi transport 1 homolog A (S. cerevisiae)	0.011
Vps52	vacuolar protein sorting 52 homolog (S. cerevisiae)	0.010
Prodh	proline dehydrogenase	0.010
Afm	afamin	0.010
Tp53i13	tumor protein p53 inducible protein 13	0.010
Nrip1	nuclear receptor interacting protein 1	0.010
LOC100360169	rCG21044-like	0.010
Tsku	tsukushin	0.010
LOC100363606	mCG147639-like	0.010
Sost	sclerosteosis	0.010
Sult1d1	sulfotransferase family 1D, member 1	0.010
Igf2bp3	insulin-like growth factor 2 mRNA binding protein 3	0.010
Dhcr7	7-dehydrocholesterol reductase	0.010
Tinag	tubulointerstitial nephritis antigen	0.010
Apol9a	apolipoprotein L 9a	0.010
Lars2	leucyl-tRNA synthetase 2, mitochondrial	0.010
Cd209b	CD209b antigen	0.010
Mcpt9	mast cell protease 9	0.010
Decr2	2,4-dienoyl CoA reductase 2, peroxisomal	0.010
Sprr3	small proline-rich protein 3	0.010
Neurog1	neurogenin 1	0.010
Oxsm	3-oxoacyl-ACP synthase, mitochondrial	0.010
Zfp362	zinc finger protein 362	0.010
Nat1	N-acetyltransferase 1	0.010
Pbsn	probasin	0.010
Dbil5	diazepam binding inhibitor-like 5	0.010
Bmp5	bone morphogenetic protein 5	0.010
Fetub	fetuin B	0.010
Slc23a3	solute carrier family 23 (nucleobase transporters), member 3	0.010
Cyp2d3	cytochrome P450, family 2, subfamily d, polypeptide 3	0.010
Mttp	microsomal triglyceride transfer protein	0.010
Stab2	stabilin 2	0.010
Rpesp	RPE-spondin	0.010
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.010
Rere	arginine-glutamic acid dipeptide (RE) repeats	0.010
LOC687813	similar to Tnf receptor-associated factor 1	0.010
LOC686412	similar to sal-like 4 isoform a	0.010
Lap3	leucine aminopeptidase 3	0.010
Mcl1	myeloid cell leukemia sequence 1	0.010
Acacb	acetyl-Coenzyme A carboxylase beta	0.010
Apoh	apolipoprotein H (beta-2-glycoprotein I)	0.010
Cd3d	CD3 molecule, delta	0.010
Rab25	RAB25, member RAS oncogene family	0.010