IMP: Integrative Multi-species Prediction

Rattus norvegicus

1 genes annotated in rat

retinal ganglion cell axon guidance

The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "retinal ganglion cell axon guidance"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "retinal ganglion cell axon guidance" (in gray)

Name	Description	Probability	Func Analog Organism
Grip1	glutamate receptor interacting protein 1	0.127
Nfib	nuclear factor I/B	0.111
Gria2	glutamate receptor, ionotropic, AMPA 2	0.100
Fgfr2	fibroblast growth factor receptor 2	0.064
Pou2f2	POU class 2 homeobox 2	0.056
Nfasc	neurofascin	0.055
Cngb1	cyclic nucleotide gated channel beta 1	0.049
Cxxc4	CXXC finger 4	0.047
Nfia	nuclear factor I/A	0.042
Pxdn	peroxidasin homolog (Drosophila)	0.040
Ddr1	discoidin domain receptor tyrosine kinase 1	0.039
Nxph1	neurexophilin 1	0.038
Grip2	glutamate receptor interacting protein 2	0.038
LOC100359879	RIKEN cDNA A830041P22-like	0.038
Pnmal2	PNMA-like 2	0.037
Robo1	roundabout homolog 1 (Drosophila)	0.037
Lamc1	laminin, gamma 1	0.034
Dact3	dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)	0.033
Abca3	ATP-binding cassette, subfamily A (ABC1), member 3	0.032
Fchsd2	FCH and double SH3 domains 2	0.032
Pcdh8	protocadherin 8	0.032
Itpr1	inositol 1,4,5-triphosphate receptor, type 1	0.030
Gpr162	G protein-coupled receptor 162	0.029
Plcl1	phospholipase C-like 1	0.029
Ager	advanced glycosylation end product-specific receptor	0.028
Fam65a	family with sequence similarity 65, member A	0.027
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.027
Src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.027
Pecam1	platelet/endothelial cell adhesion molecule 1	0.027
Daam1	dishevelled associated activator of morphogenesis 1	0.027
Ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.027
Tnc	tenascin C	0.026
Myh10	myosin, heavy chain 10, non-muscle	0.026
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.026
Phka1	phosphorylase kinase, alpha 1	0.025
Rcn1	reticulocalbin 1, EF-hand calcium binding domain	0.025
Slc1a1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	0.025
Lrch4	leucine-rich repeats and calponin homology (CH) domain containing 4	0.025
Foxe3	forkhead box E3	0.024
Gjd2	gap junction protein, delta 2	0.024
Fam57b	family with sequence similarity 57, member B	0.024
Spdya	speedy homolog A (Xenopus laevis)	0.024
Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.024
Zfp382	zinc finger protein 382	0.023
Amph	amphiphysin	0.023
Hrk	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.023
Ptprg	protein tyrosine phosphatase, receptor type, G	0.023
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.023
Pdyn	prodynorphin	0.022
Drd4	dopamine receptor D4	0.022
Nrxn1	neurexin 1	0.022
Pold3	polymerase (DNA-directed), delta 3, accessory subunit	0.022
Alpk3	alpha-kinase 3	0.022
Slc28a1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.022
Ptprk	protein tyrosine phosphatase, receptor type, K, extracellular region	0.022
Plcb1	phospholipase C, beta 1 (phosphoinositide-specific)	0.022
Ank2	ankyrin 2, neuronal	0.021
Ecel1	endothelin converting enzyme-like 1	0.021
Trim2	tripartite motif-containing 2	0.021
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.021
Ghrh	growth hormone releasing hormone	0.021
Lrp2	low density lipoprotein-related protein 2	0.021
Ankrd43	ankyrin repeat domain 43	0.020
Nlgn3	neuroligin 3	0.020
Axin1	axin 1	0.020
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.020
Ncam1	neural cell adhesion molecule 1	0.019
Dnah1	dynein, axonemal, heavy chain 1	0.019
Six3	SIX homeobox 3	0.019
Axin2	axin 2	0.019
Cnnm1	cyclin M1	0.019
Fbxo16	F-box protein 16	0.019
Gabrb1	gamma-aminobutyric acid (GABA) A receptor, beta 1	0.019
Enpp1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.018
Myh9	myosin, heavy chain 9, non-muscle	0.018
Gzmm	granzyme M (lymphocyte met-ase 1)	0.018
Rgr	retinal G protein coupled receptor	0.018
Clcn4-2	chloride channel 4-2	0.018
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.018
Grm3	glutamate receptor, metabotropic 3	0.018
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.018
Kcnk12	potassium channel, subfamily K, member 12	0.018
Dixdc1	DIX domain containing 1	0.018
Lenep	lens epithelial protein	0.018
LOC302999	similar to tripartite motif protein 32	0.018
Glg1	golgi apparatus protein 1	0.018
Kcnt1	potassium channel, subfamily T, member 1	0.018
Elk3	ELK3, ETS-domain protein	0.018
Snph	syntaphilin	0.017
Cdh2	cadherin 2	0.017
Pcdh1	protocadherin 1	0.017
Cad	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.017
Fgf8	fibroblast growth factor 8	0.017
Mdga1	MAM domain containing glycosylphosphatidylinositol anchor 1	0.017
Angpt2	angiopoietin 2	0.017
Oxt	oxytocin, prepropeptide	0.017
Tsga10	testis specific 10	0.017
Lphn2	latrophilin 2	0.017
RGD1560880	similar to RIKEN cDNA 2310002J15	0.017
Znf76	zinc finger protein 76 (expressed in testis)	0.017
Klk1c10	T-kininogenase	0.017
Epha7	Eph receptor A7	0.017	Mouse
Fgfr4	fibroblast growth factor receptor 4	0.017
Fcho1	FCH domain only 1	0.017
Tcerg1l	transcription elongation regulator 1-like	0.017
Ddah1	dimethylarginine dimethylaminohydrolase 1	0.017
Tpcn1	two pore segment channel 1	0.017
Add3	adducin 3 (gamma)	0.017
Sdc3	syndecan 3	0.017
Kcnj14	potassium inwardly-rectifying channel, subfamily J, member 14	0.017
Chrna6	cholinergic receptor, nicotinic, alpha 6	0.016
Marcks	myristoylated alanine rich protein kinase C substrate	0.016
Syt9	synaptotagmin IX	0.016
RGD1565166	similar to MGC45438 protein	0.016
Eif2c1	eukaryotic translation initiation factor 2C, 1	0.016
Ctsr	cathepsin R	0.016
Gzmc	granzyme C	0.016
Neurod1	neurogenic differentiation 1	0.016
Tril	TLR4 interactor with leucine-rich repeats	0.016
Maoa	monoamine oxidase A	0.016
Pax8	paired box 8	0.016
Camk1g	calcium/calmodulin-dependent protein kinase IG	0.016
Notch1	Notch homolog 1, translocation-associated (Drosophila)	0.016
Cttnbp2	cortactin binding protein 2	0.016
Masp1	mannan-binding lectin serine peptidase 1	0.015
Caskin1	CASK interacting protein 1	0.015
Gdf11	growth differentiation factor 11	0.015
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.015
Cadm1	cell adhesion molecule 1	0.015
Tubb4	tubulin, beta 4	0.015
Hoxa4	homeo box A4	0.015
Mgll	monoglyceride lipase	0.015
Sox12	SRY (sex determining region Y)-box 12	0.015
Ptpro	protein tyrosine phosphatase, receptor type, O	0.015
Timm44	translocase of inner mitochondrial membrane 44 homolog (yeast)	0.015
Sardh	sarcosine dehydrogenase	0.014
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.014
Gnb3	guanine nucleotide binding protein (G protein), beta polypeptide 3	0.014
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.014
Mpp2	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	0.014
Rasl10b	RAS-like, family 10, member B	0.014
Rnf182	ring finger protein 182	0.014
Bcr	breakpoint cluster region	0.014
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.014
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.014
Dapk2	death-associated kinase 2	0.014
B4galnt4	beta-1,4-N-acetyl-galactosaminyl transferase 4	0.014
Syt3	synaptotagmin III	0.014
Plxnb2	plexin B2	0.014
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.014
Rgs12	regulator of G-protein signaling 12	0.014
Flt4	fms-related tyrosine kinase 4	0.014
Tmem216	transmembrane protein 216	0.014
Unc5b	unc-5 homolog B (C. elegans)	0.014
Hrh3	histamine receptor H3	0.014
Sh3gl2	SH3-domain GRB2-like 2	0.014
Avp	arginine vasopressin	0.014
Chd3	chromodomain helicase DNA binding protein 3	0.014
Ppfia2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	0.014
Utrn	utrophin	0.014
Ralgds	ral guanine nucleotide dissociation stimulator	0.013
Pick1	protein interacting with PRKCA 1	0.013
Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	0.013
Hoxb7	homeo box B7	0.013
Stac2	SH3 and cysteine rich domain 2	0.013
Tbx1	T-box 1	0.013
Camk2n2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.013
Hapln1	hyaluronan and proteoglycan link protein 1	0.013
Tgfbr1	transforming growth factor, beta receptor 1	0.013
Lipe	lipase, hormone sensitive	0.013
Abcb9	ATP-binding cassette, subfamily B (MDR/TAP), member 9	0.013
Acsl5	acyl-CoA synthetase long-chain family member 5	0.013
Rxra	retinoid X receptor alpha	0.013
Klhl13	kelch-like 13 (Drosophila)	0.013
Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	0.013
Irf3	interferon regulatory factor 3	0.013
Chrna4	cholinergic receptor, nicotinic, alpha 4	0.013
Meis2	Meis homeobox 2	0.013
Epha8	Eph receptor A8	0.013
Gpr155	G protein-coupled receptor 155	0.013
Dclk2	doublecortin-like kinase 2	0.013
Kit	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.013
Macf1	microtubule-actin crosslinking factor 1	0.013
Chrm4	cholinergic receptor, muscarinic 4	0.013
Brca1	breast cancer 1	0.013
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.013
Sv2a	synaptic vesicle glycoprotein 2a	0.013
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.013
Myo1e	myosin IE	0.013
LOC680835	similar to cullin 7	0.013
Smad1	SMAD family member 1	0.013
Btnl1	butyrophilin-like 1	0.013
Asah2	N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2	0.013
Dab2	disabled homolog 2 (Drosophila)	0.013
Notch2	Notch homolog 2 (Drosophila)	0.013
Ptprc	protein tyrosine phosphatase, receptor type, C	0.013
Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.013
Tns1	tensin 1	0.013
Vcam1	vascular cell adhesion molecule 1	0.013
Ptprj	protein tyrosine phosphatase, receptor type, J	0.013
Nfat5	nuclear factor of activated T-cells 5	0.013
S1pr5	sphingosine-1-phosphate receptor 5	0.013
Sema4g	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G	0.013
Kcnd2	potassium voltage-gated channel, Shal-related subfamily, member 2	0.013
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.013
Nrcam	neuronal cell adhesion molecule	0.013
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.012
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.012
RGD1563533	similar to novel protein	0.012
Robo2	roundabout homolog 2 (Drosophila)	0.012
Astn1	astrotactin 1	0.012
Unc13d	unc-13 homolog D (C. elegans)	0.012
Adprhl2	ADP-ribosylhydrolase like 2	0.012
Gria3	glutamate receptor, ionotrophic, AMPA 3	0.012
Tgfb2	transforming growth factor, beta 2	0.012
Lrrc46	leucine rich repeat containing 46	0.012
Foxd4	forkhead box D4	0.012
Prpg1	proline-rich proteoglycan 1	0.012
Btbd2	BTB (POZ) domain containing 2	0.012
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.012
Lppr3	lipid phosphate phosphatase-related protein type 3	0.012
Crygd	crystallin, gamma D	0.012
Plcg2	phospholipase C, gamma 2	0.012
Sez6l2	seizure related 6 homolog (mouse)-like 2	0.012
RGD1566084	similar to Hypothetical protein LOC73072	0.012
Brsk2	BR serine/threonine kinase 2	0.012
Sorbs2	sorbin and SH3 domain containing 2	0.012
Slc25a27	solute carrier family 25, member 27	0.012
Gabra1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.012
Trdmt1	tRNA aspartic acid methyltransferase 1	0.012
Birc7	baculoviral IAP repeat-containing 7	0.012
Cbln1	cerebellin 1 precursor	0.012
Gsk3a	glycogen synthase kinase 3 alpha	0.012
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.012
RGD1563888	similar to DNA segment, Chr 16, ERATO Doi 472, expressed	0.012
Cdkn1c	cyclin-dependent kinase inhibitor 1C	0.012
Kdr	kinase insert domain receptor	0.012
RGD1565591	similar to Ski protein	0.012
Actn4	actinin alpha 4	0.012
Lyst	lysosomal trafficking regulator	0.012
Chgb	chromogranin B	0.012
Gabra3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.012
Ccne1	cyclin E1	0.012
Pbx2	pre-B-cell leukemia homeobox 2	0.012
Gtlf3b	gene trap locus F3b	0.012
Rab11fip4	RAB11 family interacting protein 4 (class II)	0.012
Fat4	FAT tumor suppressor homolog 4 (Drosophila)	0.012
Mfhas1	malignant fibrous histiocytoma amplified sequence 1	0.012
Sf1	splicing factor 1	0.012
LOC682105	similar to receptor expression enhancing protein 2	0.012
Ntf3	neurotrophin 3	0.012
Kif26b	kinesin family member 26B	0.012
Fam116b	family with sequence similarity 116, member B	0.012
Ptprs	protein tyrosine phosphatase, receptor type, S	0.012
Spag4	sperm associated antigen 4	0.011
Kcna6	potassium voltage gated channel, shaker related subfamily, member 6	0.011
Neurod2	neurogenic differentiation 2	0.011
Rlbp1	retinaldehyde binding protein 1	0.011
Gria1	glutamate receptor, ionotropic, AMPA 1	0.011
Sox13	SRY (sex determining region Y)-box 13	0.011
Rap2ip	Rap2 interacting protein	0.011
Ppp1r1b	protein phosphatase 1, regulatory (inhibitor) subunit 1B	0.011
Ptk7	PTK7 protein tyrosine kinase 7	0.011
Cacna1f	calcium channel, voltage-dependent, L type, alpha 1F subunit	0.011
Mllt4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.011
Alcam	activated leukocyte cell adhesion molecule	0.011	Zebrafish
Ctnnd2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.011
Pitx1	paired-like homeodomain 1	0.011
Tubgcp6	tubulin, gamma complex associated protein 6	0.011
Fam123a	family with sequence similarity 123A	0.011
Nrm	nurim (nuclear envelope membrane protein)	0.011
Cacna1i	calcium channel, voltage-dependent, T type, alpha 1I subunit	0.011
Rnasen	ribonuclease type III, nuclear	0.011
Plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.011
Plxdc2	plexin domain containing 2	0.011
Pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.011
Ets1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.011
Atoh8	atonal homolog 8 (Drosophila)	0.011
Isl2	ISL LIM homeobox 2	0.011	Mouse
Xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1	0.011
Tcf3	transcription factor 3	0.011
Dlg2	discs, large homolog 2 (Drosophila)	0.011
Guca1b	guanylate cyclase activator 1B	0.011
Pgap2	post-GPI attachment to proteins 2	0.011
Eps8l1	EPS8-like 1	0.011
Tnfsf13	tumor necrosis factor (ligand) superfamily, member 13	0.011
Lphn3	latrophilin 3	0.011
Tbl1xr1	transducin (beta)-like 1 X-linked receptor 1	0.011
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.011
Syt17	synaptotagmin XVII	0.011
Tmie	transmembrane inner ear	0.011
Igfbp5	insulin-like growth factor binding protein 5	0.011
Rab3c	RAB3C, member RAS oncogene family	0.011
Chka	choline kinase alpha	0.011
Hrnbp3	hexaribonucleotide binding protein 3	0.011
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.011
Fbxw9	F-box and WD repeat domain containing 9	0.011
Gfi1b	growth factor independent 1B transcription repressor	0.011
Ctxn1	cortexin 1	0.011
Rnf26	ring finger protein 26	0.011
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.011
LOC313672	kazrin	0.011
Dmrtc1a	DMRT-like family C1a	0.010
Tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.010
Atp2b3	ATPase, Ca++ transporting, plasma membrane 3	0.010
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.010
Epn1	Epsin 1	0.010
Sptbn4	spectrin, beta, non-erythrocytic 4	0.010
Ppm1j	protein phosphatase 1J	0.010
Amn	amnionless homolog (mouse)	0.010
Foxp4	forkhead box P4	0.010
RGD1560778	similar to RIKEN cDNA 6530418L21	0.010
Adam1a	a disintegrin and metallopeptidase domain 1a	0.010
Trps1	trichorhinophalangeal syndrome I homolog (human)	0.010
Prkca	protein kinase C, alpha	0.010
Mmp16	matrix metallopeptidase 16	0.010
Gk	glycerol kinase	0.010
Plxnd1	plexin D1	0.010
Slc22a15	solute carrier family 22, member 15	0.010
Drd1a	dopamine receptor D1A	0.010
Kazald1	Kazal-type serine peptidase inhibitor domain 1	0.010
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.010
Ccdc106	coiled-coil domain containing 106	0.010
Tceb3	transcription elongation factor B (SIII), polypeptide 3	0.010
Bcan	brevican	0.010
Capn6	calpain 6	0.010
Sbk1	SH3-binding domain kinase 1	0.010
Bcar1	breast cancer anti-estrogen resistance 1	0.010
Tgfb3	transforming growth factor, beta 3	0.010
Nkx2-1	NK2 homeobox 1	0.010
Ccnd2	cyclin D2	0.010
Strn	striatin, calmodulin binding protein	0.010
Accn2	amiloride-sensitive cation channel 2, neuronal	0.010
Dpysl2	dihydropyrimidinase-like 2	0.010
Prph	peripherin	0.010
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.010
Ugcg	UDP-glucose ceramide glucosyltransferase	0.010