IMP: Integrative Multi-species Prediction

Rattus norvegicus

12 genes annotated in rat

Multi-species View

positive regulation of adenylate cyclase activity

GO:0045762

Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of adenylate cyclase activity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of adenylate cyclase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Ncan	neurocan	0.269
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.229
S100a10	S100 calcium binding protein A10	0.198
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.179
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.162
Fgf14	fibroblast growth factor 14	0.147
Chrna7	cholinergic receptor, nicotinic, alpha 7	0.098
Adora1	adenosine A1 receptor	0.093
Plin	perilipin	0.090
Calm1	calmodulin 1	0.083
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.080
Gpr6	G protein-coupled receptor 6	0.079
Nfasc	neurofascin	0.076
Csf1	colony stimulating factor 1 (macrophage)	0.072
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	0.067
Slc18a3	solute carrier family 18 (vesicular acetylcholine), member 3	0.064
Adora2a	adenosine A2a receptor	0.061	Human
Kalrn	kalirin, RhoGEF kinase	0.059
Kcnh7	potassium voltage-gated channel, subfamily H (eag-related), member 7	0.059
Lgals3	lectin, galactoside-binding, soluble, 3	0.056
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.055
Ifitm3	interferon induced transmembrane protein 3	0.051
Drd2	dopamine receptor D2	0.051
Odf4	outer dense fiber of sperm tails 4	0.047
Avp	arginine vasopressin	0.044
Camk4	calcium/calmodulin-dependent protein kinase IV	0.043
Hpcal4	hippocalcin-like 4	0.042
Prl2a1	Prolactin family 2, subfamily a, member 1	0.042
Mcpt1	mast cell protease 1	0.040
Gng7	guanine nucleotide binding protein (G protein), gamma 7	0.040
Pde1b	phosphodiesterase 1B, calmodulin-dependent	0.040
Syt7	synaptotagmin VII	0.039
Gpr176	G protein-coupled receptor 176	0.039
Gad2	glutamate decarboxylase 2	0.038
Vim	vimentin	0.038
Hrh2	histamine receptor H 2	0.038	Rat
Kitlg	KIT ligand	0.037
Taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.037
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.035
Folh1	folate hydrolase 1	0.034
Anxa5	annexin A5	0.034
Gabra3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.033
Calm2	calmodulin 2	0.033
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.033
Insr	insulin receptor	0.033
Ptp4a2	protein tyrosine phosphatase 4a2	0.032
Rgs9	regulator of G-protein signaling 9	0.031
Sfrp4	secreted frizzled-related protein 4	0.031
Cx3cr1	chemokine (C-X3-C motif) receptor 1	0.031
Hpca	hippocalcin	0.031
Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.031
Prrx1	paired related homeobox 1	0.030
Kcnq3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.029
Gabra4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	0.029
Utrn	utrophin	0.028
Grm1	glutamate receptor, metabotropic 1	0.028
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.028
N5	DNA binding protein N5	0.028
Pgam1	phosphoglycerate mutase 1 (brain)	0.028
Cckar	cholecystokinin A receptor	0.027
Cav1	caveolin 1, caveolae protein	0.027
Anxa2	annexin A2	0.026
Kcnc2	potassium voltage gated channel, Shaw-related subfamily, member 2	0.026
RGD1564327	similar to integrin alpha 8	0.025
Mchr1	melanin-concentrating hormone receptor 1	0.025
Lims1	LIM and senescent cell antigen-like domains 1	0.025
Olr416	olfactory receptor 416	0.025
Dlx5	distal-less homeobox 5	0.024
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.024
Igf2	insulin-like growth factor 2	0.024
Ptger3	prostaglandin E receptor 3 (subtype EP3)	0.024
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.024
Adam10	ADAM metallopeptidase domain 10	0.023
Cntn3	contactin 3 (plasmacytoma associated)	0.023
S100a4	S100 calcium-binding protein A4	0.023
Uhmk1	U2AF homology motif (UHM) kinase 1	0.023
Sepw1	selenoprotein W, 1	0.023
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.023
Sub1	SUB1 homolog (S. cerevisiae)	0.023
Soat1	sterol O-acyltransferase 1	0.022
Grik3	glutamate receptor, ionotropic, kainate 3	0.022
Unc5a	unc-5 homolog A (C. elegans)	0.022
Znf483	zinc finger protein 483	0.022
Crhbp	corticotropin releasing hormone binding protein	0.022
Neu2	sialidase 2 (cytosolic sialidase)	0.022
Tpsb2	tryptase beta 2	0.022
Aqp2	aquaporin 2 (collecting duct)	0.022
Myo1b	myosin Ib	0.022
Fgf7	fibroblast growth factor 7	0.022
Dynll1	dynein light chain LC8-type 1	0.021
Adam3a	ADAM metallopeptidase domain 3A (cyritestin 1)	0.021
Dock8	dedicator of cytokinesis 8	0.021
Map3k3	mitogen activated protein kinase kinase kinase 3	0.021
Gabrr1	gamma-aminobutyric acid (GABA) receptor, rho 1	0.021
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.020
Agtr1a	angiotensin II receptor, type 1a	0.020
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.020
Emp1	epithelial membrane protein 1	0.020
Syt8	synaptotagmin VIII	0.020
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.020
Grin3a	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	0.020
Kcnb2	potassium voltage gated channel, Shab-related subfamily, member 2	0.020
Cyss	cystatin S	0.019
Csrnp2	cysteine-serine-rich nuclear protein 2	0.019
Sgp158	proline-rich glycoprotein (sgp158)	0.019
Calcrl	calcitonin receptor-like	0.019	Rat
Pcyt1b	phosphate cytidylyltransferase 1, choline, beta	0.019
Cga	glycoprotein hormones, alpha polypeptide	0.019
RGD1559748	similar to Palate lung and nasal carcinoma-like protein precursor (Tongue plunc-like protein)	0.019
Hoxa4	homeo box A4	0.019
Oprk1	opioid receptor, kappa 1	0.019
Cd14	CD14 molecule	0.019
Olr1366	olfactory receptor 1366	0.018
Cckbr	cholecystokinin B receptor	0.018
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.018
Kynu	kynureninase (L-kynurenine hydrolase)	0.018
Sert1	Sertoli cell protein 1	0.018
Arc	activity-regulated cytoskeleton-associated protein	0.018
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.018
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.018
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.018
Vipr2	vasoactive intestinal peptide receptor 2	0.018
Rgs12	regulator of G-protein signaling 12	0.018
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.018
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.017
Olr1530	olfactory receptor 1530	0.017
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.017
Prdm2	PR domain containing 2, with ZNF domain	0.016
Phkg1	phosphorylase kinase, gamma 1	0.016
Kcna5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.016
Slc14a1	solute carrier family 14 (urea transporter), member 1	0.016
Fkbp1a	FK506 binding protein 1a	0.016
Rftn2	raftlin family member 2	0.016
Hsbp1	heat shock factor binding protein 1	0.016
Prkg2	protein kinase, cGMP-dependent, type II	0.016
Vom2r52	vomeronasal 2 receptor, 52	0.016
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.016
Shank1	SH3 and multiple ankyrin repeat domains 1	0.016
Gabrd	gamma-aminobutyric acid (GABA) A receptor, delta	0.016
Chrm1	cholinergic receptor, muscarinic 1	0.016
Stk39	serine/threonine kinase 39, STE20/SPS1 homolog (yeast)	0.016
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.016
Prl4a1	prolactin family 4, subfamily a, member 1	0.016
Tacr1	tachykinin receptor 1	0.015
Epn2	epsin 2	0.015
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.015
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.015
Adra2c	adrenergic, alpha-2C-, receptor	0.015	Rat
Ocm	oncomodulin	0.015
Creb1	cAMP responsive element binding protein 1	0.015
Aif1l	allograft inflammatory factor 1-like	0.015
Shox2	short stature homeobox 2	0.015
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.015
Rem2	RAS (RAD and GEM) like GTP binding 2	0.015
Asb9	ankyrin repeat and SOCS box-containing 9	0.015
Dnah9	dynein, axonemal, heavy polypeptide 9	0.015
Olr287	olfactory receptor 287	0.015
Lep	leptin	0.015
Oxtr	oxytocin receptor	0.015
Nrarp	Notch-regulated ankyrin repeat protein	0.014
Olr1500	olfactory receptor 1500	0.014
Fuca1	fucosidase, alpha-L- 1, tissue	0.014
Gnb4	guanine nucleotide binding protein (G protein), beta polypeptide 4	0.014
Olr1082	olfactory receptor 1082	0.014
Ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.014
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.014
Rho	rhodopsin	0.014
Trhr	thyrotropin releasing hormone receptor	0.013
Neurod2	neurogenic differentiation 2	0.013
Mamdc4	MAM domain containing 4	0.013
Ube2m	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.013
Synpo	synaptopodin	0.013
Avpr1b	arginine vasopressin receptor 1B	0.013
Plau	plasminogen activator, urokinase	0.013
Capg	capping protein (actin filament), gelsolin-like	0.013
Tm2d2	TM2 domain containing 2	0.013
Fgf2	fibroblast growth factor 2	0.013
Pdyn	prodynorphin	0.013
Ccl2	chemokine (C-C motif) ligand 2	0.013
Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform	0.013
Cst8	cystatin 8 (cystatin-related epididymal specific)	0.013
Nos3	nitric oxide synthase 3, endothelial cell	0.013
Agtr2	angiotensin II receptor, type 2	0.013
Chrna2	cholinergic receptor, nicotinic, alpha 2 (neuronal)	0.013
Hrh1	histamine receptor H 1	0.013
Clcn3	chloride channel 3	0.013
LOC360479	similar to hypothetical protein	0.013
Cacng5	calcium channel, voltage-dependent, gamma subunit 5	0.012
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1	0.012
Gabrq	gamma-aminobutyric acid (GABA) receptor, theta	0.012
Ncr1	natural cytotoxicity triggering receptor 1	0.012
Chrna1	cholinergic receptor, nicotinic, alpha 1 (muscle)	0.012
Oprd1	opioid receptor, delta 1	0.012
Rin1	Ras and Rab interactor 1	0.012
Cmklr1	chemokine-like receptor 1	0.012
Galr2	galanin receptor 2	0.012
Pigl	phosphatidylinositol glycan anchor biosynthesis, class L	0.012
F2rl1	coagulation factor II (thrombin) receptor-like 1	0.012
Camkk2	calcium/calmodulin-dependent protein kinase kinase 2, beta	0.012
Testin	testin gene	0.012
Cxcr5	chemokine (C-X-C motif) receptor 5	0.012
Teddm1	transmembrane epididymal protein 1	0.012
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.012
Pecam1	platelet/endothelial cell adhesion molecule 1	0.012
Hoxa2	homeo box A2	0.012
Pla2g2c	phospholipase A2, group IIC	0.012
Kcnh6	potassium voltage-gated channel, subfamily H (eag-related), member 6	0.012
Fn3k	fructosamine 3 kinase	0.012
LOC679840	similar to germinal histone H4 gene	0.012
Tmod2	tropomodulin 2	0.012
Dcc	deleted in colorectal carcinoma	0.011
Egr4	early growth response 4	0.011
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.011
Mapk4	mitogen-activated protein kinase 4	0.011
Cntn4	contactin 4	0.011
Chrna6	cholinergic receptor, nicotinic, alpha 6	0.011
Nr4a2	nuclear receptor subfamily 4, group A, member 2	0.011
Epha8	Eph receptor A8	0.011
Nudt3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.011
Gpr88	G-protein coupled receptor 88	0.011
Cdc34	cell division cycle 34 homolog (S. cerevisiae)	0.011
Stat5b	signal transducer and activator of transcription 5B	0.011
Bsn	bassoon	0.011
Pgp	phosphoglycolate phosphatase	0.011
Hcrt	hypocretin	0.011
Mapk9	mitogen-activated protein kinase 9	0.011
Cfp	complement factor properdin	0.011
Hcrtr2	hypocretin (orexin) receptor 2	0.011
Ifnb1	interferon beta 1, fibroblast	0.010
Gpr1	G protein-coupled receptor 1	0.010
Cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.010
Isl1	ISL LIM homeobox 1	0.010
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.010
Ak1	adenylate kinase 1	0.010
Slc6a7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.010
Cd4	Cd4 molecule	0.010
Olr1191	olfactory receptor 1191	0.010
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.010
Catsper2	cation channel, sperm associated 2	0.010
Lama5	laminin, alpha 5	0.010
Gabrr3	gamma-aminobutyric acid (GABA) receptor, rho 3	0.010
Cyp4a8	cytochrome P450, family 4, subfamily a, polypeptide 8	0.010
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.010
Apoa4	apolipoprotein A-IV	0.010