IMP: Integrative Multi-species Prediction

Rattus norvegicus

2 genes annotated in rat

Multi-species View

negative regulation of vesicle fusion

GO:0031339

Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of vesicle fusion"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of vesicle fusion" (in gray)

Name	Description	Probability	Func Analog Organism
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.585
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.456
Dlg4	discs, large homolog 4 (Drosophila)	0.385
Amph	amphiphysin	0.325
Syn1	synapsin I	0.274
Syt1	synaptotagmin I	0.198	Rat
Unc5a	unc-5 homolog A (C. elegans)	0.151
Freq	frequenin homolog (Drosophila)	0.146
Kcnip3	Kv channel interacting protein 3, calsenilin	0.142
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.130
Rims1	regulating synaptic membrane exocytosis 1	0.121
Syt11	synaptotagmin XI	0.110	Rat
Kcnc2	potassium voltage gated channel, Shaw-related subfamily, member 2	0.106
Crhbp	corticotropin releasing hormone binding protein	0.100
Tmem59l	transmembrane protein 59-like	0.090
Clstn3	calsyntenin 3	0.090
Sstr3	somatostatin receptor 3	0.087
Gucy2g	guanylate cyclase 2G	0.087
Kcnq2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.083
Kcnk1	potassium channel, subfamily K, member 1	0.083
Gnaz	guanine nucleotide binding protein (G protein), alpha z polypeptide	0.078
Tnr	tenascin R	0.072
Laptm5	lysosomal protein transmembrane 5	0.070
Syt4	synaptotagmin IV	0.069
Unc13a	unc-13 homolog A (C. elegans)	0.062
Bsn	bassoon	0.061
Gad1	glutamate decarboxylase 1	0.054
Dio2	deiodinase, iodothyronine, type II	0.053
Neurod2	neurogenic differentiation 2	0.052
Sncb	synuclein, beta	0.051
Kcnv1	potassium channel, subfamily V, member 1	0.051
Kif6	kinesin family member 6	0.050
Grm2	glutamate receptor, metabotropic 2	0.049
Egr3	early growth response 3	0.046
Cspg5	chondroitin sulfate proteoglycan 5	0.045
Limd2	LIM domain containing 2	0.043
Syn2	synapsin II	0.041
Scn2b	sodium channel, voltage-gated, type II, beta	0.041
Gabbr1	gamma-aminobutyric acid (GABA) B receptor 1	0.041
Spock1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.040
Gabrd	gamma-aminobutyric acid (GABA) A receptor, delta	0.039
Faim2	Fas apoptotic inhibitory molecule 2	0.037
Grid2	glutamate receptor, ionotropic, delta 2	0.036
Cyp2b21	cytochrome P450, family 2, subfamily b, polypeptide 21	0.036
Olr1641	olfactory receptor 1641	0.036
Adrbk2	adrenergic, beta, receptor kinase 2	0.036
Csrnp2	cysteine-serine-rich nuclear protein 2	0.036
Cplx1	complexin 1	0.036
Cacna1i	calcium channel, voltage-dependent, T type, alpha 1I subunit	0.036
C1ql1	complement component 1, q subcomponent-like 1	0.035
St18	suppression of tumorigenicity 18	0.034
Mapk10	mitogen activated protein kinase 10	0.033
Zfp382	zinc finger protein 382	0.033
Camk2n2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.032
Cartpt	CART prepropeptide	0.031
Grm1	glutamate receptor, metabotropic 1	0.030
Hcn1	hyperpolarization-activated cyclic nucleotide-gated potassium channel 1	0.030
Gnao1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.029
Pcsk2	proprotein convertase subtilisin/kexin type 2	0.029
Rab15	RAB15, member RAS oncogene family	0.029
Hpcal4	hippocalcin-like 4	0.029
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.029
Cotl1	coactosin-like 1 (Dictyostelium)	0.028
Mpp3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	0.027
Chrna9	cholinergic receptor, nicotinic, alpha 9	0.027
Cyp2a3	cytochrome P450, family 2, subfamily a, polypeptide 3	0.027
Syt7	synaptotagmin VII	0.027	Rat
Syt6	synaptotagmin VI	0.026	Rat
Galr1	galanin receptor 1	0.026
Dpp6	dipeptidylpeptidase 6	0.025
Hn1	hematological and neurological expressed 1	0.024
Znf689	zinc finger protein 689	0.024
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.024
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.023
Fgf14	fibroblast growth factor 14	0.023
Sez6l2	seizure related 6 homolog (mouse)-like 2	0.023
Grin1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.023
Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform	0.023
Cdh15	cadherin 15	0.023
Pip4k2b	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	0.023
Rasgrp1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	0.022
Syt9	synaptotagmin IX	0.022	Rat
RT1-M4	RT1 class Ib, locus M4	0.021
Kcnk12	potassium channel, subfamily K, member 12	0.021
Mas1	MAS1 oncogene	0.021
Rph3a	rabphilin 3A	0.021
Rnf208	ring finger protein 208	0.021
Snap25	synaptosomal-associated protein 25	0.021
Neu2	sialidase 2 (cytosolic sialidase)	0.021
Sh3gl2	SH3-domain GRB2-like 2	0.020
Pex5l	peroxisomal biogenesis factor 5-like	0.020
Pdzd2	PDZ domain containing 2	0.020
Epha8	Eph receptor A8	0.020
Vip	vasoactive intestinal peptide	0.019
Hbe1	hemoglobin, epsilon 1	0.019
Gpha2	glycoprotein hormone alpha 2	0.019
Tub	tubby homolog (mouse)	0.019
Ecel1	endothelin converting enzyme-like 1	0.019
Syt10	synaptotagmin X	0.019	Rat
Adra2c	adrenergic, alpha-2C-, receptor	0.018
Adcyap1r1	adenylate cyclase activating polypeptide 1 receptor 1	0.018
Gpsm1	G-protein signaling modulator 1 (AGS3-like, C. elegans)	0.018
Ccbp2	chemokine binding protein 2	0.017
Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	0.017
Cplx2	complexin 2	0.017
Kcnf1	potassium voltage-gated channel, subfamily F, member 1	0.017
Atp2a3	ATPase, Ca++ transporting, ubiquitous	0.017
Uhmk1	U2AF homology motif (UHM) kinase 1	0.017
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.017
Rgs10	regulator of G-protein signaling 10	0.017
B3gnt7	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7	0.017
Eef1a2	eukaryotic translation elongation factor 1 alpha 2	0.016
Scg2	secretogranin II (chromogranin C)	0.016
Cntn3	contactin 3 (plasmacytoma associated)	0.016
Gabra4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	0.016
Slc9a4	solute carrier family 9 (sodium/hydrogen exchanger), member 4	0.016
Syt13	synaptotagmin XIII	0.016	Rat
Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3	0.016
Scn8a	sodium channel, voltage gated, type VIII, alpha subunit	0.016
Snrpn	small nuclear ribonucleoprotein polypeptide N	0.015
Nhlh1	nescient helix loop helix 1	0.015
Slco1a5	solute carrier organic anion transporter family, member 1a5	0.015
Pcyt1b	phosphate cytidylyltransferase 1, choline, beta	0.015
Gad2	glutamate decarboxylase 2	0.015
Olr1271	olfactory receptor 1271	0.015
Cntn1	contactin 1	0.015
Sec14l3	SEC14-like 3 (S. cerevisiae)	0.015
Vps52	vacuolar protein sorting 52 homolog (S. cerevisiae)	0.015
Odf4	outer dense fiber of sperm tails 4	0.014
Htr3a	5-hydroxytryptamine (serotonin) receptor 3a	0.014
Doc2a	double C2-like domains, alpha	0.014
Glrb	glycine receptor, beta	0.014
Fitm1	fat storage-inducing transmembrane protein 1	0.014
Gria1	glutamate receptor, ionotropic, AMPA 1	0.014
Lbxcor1	LBXCOR1 homolog (mouse)	0.014
Ppfia3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	0.014
Accn1	amiloride-sensitive cation channel 1, neuronal	0.014
Rab3a	RAB3A, member RAS oncogene family	0.014
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.014
LOC684560	hypothetical protein LOC684560	0.014
Pde1b	phosphodiesterase 1B, calmodulin-dependent	0.014
Gmfg	glia maturation factor, gamma	0.014
Vamp1	vesicle-associated membrane protein 1	0.013
Slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	0.013
Pde4d	phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)	0.013
Adam6	a disintegrin and metallopeptidase domain 6	0.013
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	0.013
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.013
Olr59	olfactory receptor 59	0.013
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.013
Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.013
Accn2	amiloride-sensitive cation channel 2, neuronal	0.013
Sv2c	synaptic vesicle glycoprotein 2c	0.013
Olr1496	olfactory receptor 1496	0.013
Ggt7	gamma-glutamyltransferase 7	0.013
Cntnap1	contactin associated protein 1	0.013
Pnliprp2	pancreatic lipase-related protein 2	0.013
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.013
Epha5	EphA5	0.013
Slc16a8	solute carrier family 16, member 8 (monocarboxylic acid transporter 3)	0.012
Ncan	neurocan	0.012
Myoc	myocilin	0.012
Lrrc10b	leucine rich repeat containing 10B	0.012
Adra2a	adrenergic, alpha-2A-, receptor	0.012
Mgat3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase	0.012
Oprl1	opiate receptor-like 1	0.012
Rgs17	regulator of G-protein signaling 17	0.012
Sptbn2	spectrin, beta, non-erythrocytic 2	0.012
Actl6b	actin-like 6B	0.012
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.012
Slc35f1	solute carrier family 35, member F1	0.012
Notch4	Notch homolog 4 (Drosophila)	0.012
Tmem151a	transmembrane protein 151A	0.012
Hapln1	hyaluronan and proteoglycan link protein 1	0.012
Tmod2	tropomodulin 2	0.012
Pfn1	profilin 1	0.012
Cadm4	cell adhesion molecule 4	0.012
Gpr173	G-protein coupled receptor 173	0.011
Baalc	brain and acute leukemia, cytoplasmic	0.011
Sstr1	somatostatin receptor 1	0.011
Lnpep	leucyl/cystinyl aminopeptidase	0.011
Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.011
Kcng3	potassium voltage-gated channel, subfamily G, member 3	0.011
Ccr3	chemokine (C-C motif) receptor 3	0.011
Mcf2l	MCF.2 cell line derived transforming sequence-like	0.011
Grm5	glutamate receptor, metabotropic 5	0.011
Alox15	arachidonate 15-lipoxygenase	0.011
Gabra3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.011
Tubb4	tubulin, beta 4	0.011
Myt1	myelin transcription factor 1	0.011
Rnps1	ribonucleic acid binding protein S1	0.011
Slc9a1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.011
Mib1	mindbomb homolog 1 (Drosophila)	0.010
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.010
Cacng6	calcium channel, voltage-dependent, gamma subunit 6	0.010
Pnck	pregnancy upregulated non-ubiquitously expressed CaM kinase	0.010
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.010
Sept3	septin 3	0.010
Prkcg	protein kinase C, gamma	0.010
Pdx1	pancreatic and duodenal homeobox 1	0.010