IMP
Process View
positive regulation of proteasomal ubiquitin dependent protein catabolic process
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of proteasomal ubiquitin dependent protein catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Mdm2 | Mdm2 p53 binding protein homolog (mouse) | 0.072 | ||
| Cops2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.058 | ||
| Ppm1b | protein phosphatase 1B, magnesium dependent, beta isoform | 0.044 | ||
| Ube2g1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | 0.041 | ||
| Psmd2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.037 | ||
| Dnaja2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | 0.033 | ||
| Pttg1 | pituitary tumor-transforming 1 | 0.033 | ||
| Zfand5 | zinc finger, AN1-type domain 5 | 0.030 | ||
| Cnbp | CCHC-type zinc finger, nucleic acid binding protein | 0.029 | ||
| Ccnb1 | cyclin B1 | 0.029 | ||
| Hprt1 | hypoxanthine phosphoribosyltransferase 1 | 0.028 | ||
| Ppp1cb | protein phosphatase 1, catalytic subunit, beta isoform | 0.026 | ||
| Rps8 | ribosomal protein S8 | 0.024 | ||
| Cdca8 | cell division cycle associated 8 | 0.024 | ||
| Psmd3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.023 | ||
| Psmc6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.023 | ||
| Eif4a2 | eukaryotic translation initiation factor 4A, isoform 2 | 0.023 | ||
| Sumo1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.022 | Human | |
| Ube2d3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.022 | ||
| Prkar1a | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.022 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.021 | ||
| Ppp1r2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.021 | ||
| Nploc4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.021 | ||
| Rpl7a | ribosomal protein L7a | 0.019 | ||
| Traf4af1 | TRAF4 associated factor 1 | 0.018 | ||
| Spag5 | sperm associated antigen 5 | 0.018 | ||
| Txnrd1 | thioredoxin reductase 1 | 0.018 | ||
| Kif22 | kinesin family member 22 | 0.018 | ||
| Rbm18 | RNA binding motif protein 18 | 0.017 | ||
| Ube2c | ubiquitin-conjugating enzyme E2C | 0.017 | ||
| Trim28 | tripartite motif-containing 28 | 0.017 | ||
| Birc5 | baculoviral IAP repeat-containing 5 | 0.016 | ||
| Picalm | phosphatidylinositol binding clathrin assembly protein | 0.016 | ||
| Dvl1 | dishevelled, dsh homolog 1 (Drosophila) | 0.016 | Human | |
| Usp47 | ubiquitin specific peptidase 47 | 0.016 | ||
| Ubr4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.016 | ||
| Tpm4 | tropomyosin 4 | 0.016 | ||
| Mtmr6 | myotubularin related protein 6 | 0.015 | ||
| Prpf38a | PRP38 pre-mRNA processing factor 38 (yeast) domain containing A | 0.015 | ||
| Dlgap5 | discs, large (Drosophila) homolog-associated protein 5 | 0.015 | ||
| Ppm1a | protein phosphatase 1A, magnesium dependent, alpha isoform | 0.014 | ||
| Trappc2 | trafficking protein particle complex 2 | 0.014 | ||
| Kif2c | kinesin family member 2C | 0.014 | ||
| Ttc35 | tetratricopeptide repeat domain 35 | 0.014 | ||
| Fn1 | fibronectin 1 | 0.014 | ||
| Axin1 | axin 1 | 0.014 | Mouse | |
| Asf1b | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.014 | ||
| Racgap1 | Rac GTPase-activating protein 1 | 0.014 | ||
| Troap | trophinin associated protein | 0.013 | ||
| Kifc1 | kinesin family member C1 | 0.013 | ||
| Tbpl1 | TATA box binding protein-like 1 | 0.013 | ||
| Plk1 | polo-like kinase 1 (Drosophila) | 0.013 | Human Rat | |
| Impdh2 | IMP (inosine monophosphate) dehydrogenase 2 | 0.013 | ||
| Atp1a1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.013 | ||
| Capns1 | calpain, small subunit 1 | 0.012 | ||
| Actr6 | ARP6 actin-related protein 6 homolog (yeast) | 0.012 | ||
| Pdcd10 | programmed cell death 10 | 0.012 | ||
| Eef2 | eukaryotic translation elongation factor 2 | 0.012 | ||
| Cdkn3 | cyclin-dependent kinase inhibitor 3 | 0.012 | ||
| Cetn3 | centrin, EF-hand protein, 3 (CDC31 homolog, yeast) | 0.012 | ||
| Pdp1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 0.012 | ||
| Ptges3 | prostaglandin E synthase 3 (cytosolic) | 0.012 | ||
| Eif3b | eukaryotic translation initiation factor 3, subunit B | 0.012 | ||
| Prc1 | protein regulator of cytokinesis 1 | 0.012 | ||
| Rpl36 | ribosomal protein L36 | 0.012 | ||
| Lsm5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.011 | ||
| Unc119b | unc-119 homolog B (C. elegans) | 0.011 | ||
| Apba3 | amyloid beta (A4) precursor protein-binding, family A, member 3 | 0.011 | ||
| Srp19 | signal recognition particle 19 | 0.011 | ||
| Fxr2 | fragile X mental retardation, autosomal homolog 2 | 0.011 | ||
| Foxm1 | forkhead box M1 | 0.011 | ||
| Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.011 | ||
| Epn1 | Epsin 1 | 0.011 | ||
| Rps5 | ribosomal protein S5 | 0.011 | ||
| Cdca3 | cell division cycle associated 3 | 0.011 | ||
| Mapre1 | microtubule-associated protein, RP/EB family, member 1 | 0.011 | ||
| Usf2 | upstream transcription factor 2, c-fos interacting | 0.011 | ||
| Rplp0 | ribosomal protein, large, P0 | 0.011 | ||
| LOC100310874 | antisense RNA overlapping MCH | 0.011 | ||
| Rpl21 | ribosomal protein L21 | 0.011 | ||
| Dyrk1a | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.011 | ||
| LOC100362155 | cysteine and histidine rich 1 | 0.011 | ||
| Hdlbp | high density lipoprotein binding protein | 0.011 | ||
| Jak2 | Janus kinase 2 | 0.011 | ||
| Ccnb2 | cyclin B2 | 0.011 | ||
| E2f1 | E2F transcription factor 1 | 0.011 | ||
| Rbm8a | RNA binding motif protein 8A | 0.011 | ||
| Mobkl3 | MOB1, Mps One Binder kinase activator-like 3 (yeast) | 0.010 | ||
| Akt1s1 | AKT1 substrate 1 (proline-rich) | 0.010 | ||
| Kif18b | kinesin family member 18B | 0.010 | ||
| Nae1 | NEDD8 activating enzyme E1 subunit 1 | 0.010 | ||
| Dusp6 | dual specificity phosphatase 6 | 0.010 | ||
| Slc48a1 | solute carrier family 48 (heme transporter), member 1 | 0.010 | ||
| Rbbp7 | retinoblastoma binding protein 7 | 0.010 | ||
| Psmd10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.010 | ||
| Acbd5 | acyl-Coenzyme A binding domain containing 5 | 0.010 | ||
| Arih1 | ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) | 0.010 | ||
| Ubqln1 | ubiquilin 1 | 0.010 | ||
| Fkbp3 | FK506 binding protein 3 | 0.010 | ||
| Rnf10 | ring finger protein 10 | 0.010 |