IMP: Integrative Multi-species Prediction

Rattus norvegicus

1 genes annotated in rat

drug catabolic process

The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "drug catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "drug catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Cyp2b1	cytochrome P450, family 2, subfamily b, polypeptide 1	0.989	Human
Cyp3a18	cytochrome P450, family 3, subfamily a, polypeptide 18	0.957	Human
Cyp2d4	cytochrome P450, family 2, subfamily d, polypeptide 4	0.950	Human
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.891
Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1	0.843
Cyp2b3	cytochrome P450, family 2, subfamily b, polypeptide 3	0.837
Cyp2d3	cytochrome P450, family 2, subfamily d, polypeptide 3	0.775	Human
Abcc6	ATP-binding cassette, subfamily C (CFTR/MRP), member 6	0.647
Sult1e1	sulfotransferase family 1E, estrogen-preferring, member 1	0.553
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.526
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.483
Akr1c18	aldo-keto reductase family 1, member C18	0.480
Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	0.473
Mettl7b	methyltransferase like 7B	0.395
Ugt2b	UDP glycosyltransferase 2 family, polypeptide B	0.356
Abcb11	ATP-binding cassette, subfamily B (MDR/TAP), member 11	0.320
LOC494499	LOC494499 protein	0.288
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.268
Crygf	crystallin, gamma F	0.227
Cyp2a2	cytochrome P450, family 2, subfamily a, polypeptide 2	0.210
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.209	Rat
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.204
Sult1b1	sulfotransferase family, cytosolic, 1B, member 1	0.190
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.187
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.186
Slco1a4	solute carrier organic anion transporter family, member 1a4	0.176
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.168
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.168
Otc	ornithine carbamoyltransferase	0.161
Cyp2b2	cytochrome P450, family 2, subfamily b, polypeptide 2	0.160	Human
LOC100365112	carboxylesterase-like	0.155
Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	0.153
Dhfr	dihydrofolate reductase	0.148
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.145
Cyp2d2	cytochrome P450, family 2, subfamily d, polypeptide 2	0.143	Human
Akr1c12	aldo-keto reductase family 1, member C12	0.143
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.143
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.140
Sult1c3	sulfotransferase family, cytosolic, 1C, member 3	0.117
Cyp3a23/3a1	cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1	0.116	Human
LOC293989	cytochrome P450-like	0.112
Dpys	dihydropyrimidinase	0.109
Olr59	olfactory receptor 59	0.105
Cyp4a8	cytochrome P450, family 4, subfamily a, polypeptide 8	0.098	Rat
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.092	Rat
Cyp2b15	cytochrome P450, family 2, subfamily b, polypeptide 15	0.091	Human
Cyp2d1	cytochrome P450, family 2, subfamily d, polypeptide 1	0.083
Fmo1	flavin containing monooxygenase 1	0.077
Olr1701	olfactory receptor 1701	0.070
Cyp2c11	cytochrome P450, subfamily 2, polypeptide 11	0.070	Human
Cyp4a2	cytochrome P450, family 4, subfamily a, polypeptide 2	0.067	Rat
Fabp1	fatty acid binding protein 1, liver	0.063
Cyp2c22	cytochrome P450, family 2, subfamily c, polypeptide 22	0.056
Ctdsp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	0.054
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.054
Cyp2f4	cytochrome P450, family 2, subfamily f, polypeptide 4	0.051
Aqp9	aquaporin 9	0.049
Azgp1	alpha-2-glycoprotein 1, zinc-binding	0.049
Nat8	N-acetyltransferase 8	0.049
Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.048
LOC100361864	UDP-glucuronosyltransferase 2B3-like	0.048
Ces1c	carboxylesterase 1C	0.046
Rxrg	retinoid X receptor gamma	0.043
Rag1	recombination activating gene 1	0.043
Acot12	acyl-CoA thioesterase 12	0.041
Gsta2	glutathione S-transferase A2	0.040
Gckr	glucokinase (hexokinase 4) regulator	0.039
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.039
Asgr1	asialoglycoprotein receptor 1	0.038
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.037
Ces1f	carboxylesterase 1F	0.037
Fdxr	ferredoxin reductase	0.036
Ces1e	carboxylesterase 1E	0.036
Zfp37	zinc finger protein 37	0.035
Ugt2b37	UDP-glucuronosyltransferase 2 family, member 37	0.035
Apob	apolipoprotein B	0.034
Dao	D-amino-acid oxidase	0.034
Rdh2	retinol dehydrogenase 2	0.034
Il8ra	interleukin 8 receptor, alpha	0.032
Cyp4f6	cytochrome P450, family 4, subfamily f, polypeptide 6	0.032	Rat
Ust5r	integral membrane transport protein UST5r	0.031
Qpct	glutaminyl-peptide cyclotransferase	0.031
Hsd17b6	hydroxysteroid (17-beta) dehydrogenase 6	0.031
Crybb1	crystallin, beta B1	0.029
Pigr	polymeric immunoglobulin receptor	0.029
Cps1	carbamoyl-phosphate synthetase 1	0.029
Gnmt	glycine N-methyltransferase	0.028
Spef2	sperm flagellar 2	0.027
Haao	3-hydroxyanthranilate 3,4-dioxygenase	0.027
Efcab4a	EF-hand calcium binding domain 4A	0.027
L3mbtl3	l(3)mbt-like 3 (Drosophila)	0.025
Ppara	peroxisome proliferator activated receptor alpha	0.024
Cyp2j4	cytochrome P450, family 2, subfamily j, polypeptide 4	0.023
RGD1306474	similar to RIKEN cDNA 9530003J23	0.023
Barhl2	BarH-like homeobox 2	0.023
Upb1	ureidopropionase, beta	0.023
Aadac	arylacetamide deacetylase (esterase)	0.022
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.022
Slco1b3	solute carrier organic anion transporter family, member 1b3	0.022
Cyss	cystatin S	0.021
Ppard	peroxisome proliferator-activated receptor delta	0.020
Camkk2	calcium/calmodulin-dependent protein kinase kinase 2, beta	0.020
Cdh17	cadherin 17	0.020
Fgfr4	fibroblast growth factor receptor 4	0.020
Sstr4	somatostatin receptor 4	0.020
G6pc	glucose-6-phosphatase, catalytic subunit	0.019
Bucs1	butyryl Coenzyme A synthetase 1	0.019
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.019
Pnlip	pancreatic lipase	0.019
Acads	acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain	0.018
Selp	selectin P	0.018
Hnmt	histamine N-methyltransferase	0.018
Cd46	CD46 molecule, complement regulatory protein	0.018
Cyp2j3	cytochrome P450, family 2, subfamily j, polypeptide 3	0.017
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.017
Cdh8	cadherin 8	0.016
Cyp3a9	cytochrome P450, family 3, subfamily a, polypeptide 9	0.016	Human
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.016
Nmu	neuromedin U	0.016
Sult1a1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	0.016
Pbld	phenazine biosynthesis-like protein domain containing	0.016
Tas2r114	taste receptor, type 2, member 114	0.015
Cst8	cystatin 8 (cystatin-related epididymal specific)	0.015
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.015
Hnf4a	hepatocyte nuclear factor 4, alpha	0.015
Akr1c1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.015
Agxt	alanine-glyoxylate aminotransferase	0.015
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.015
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.015
Kcnd3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.014
Cyp2b12	cytochrome P450, family 2, subfamily b, polypeptide 12	0.014	Human
Cyp27a1	cytochrome P450, family 27, subfamily a, polypeptide 1	0.014
Prl8a4	prolactin family 8, subfamily a, member 4	0.013
Serpina5	serine (or cysteine) peptidase inhibitor, clade A, member 5	0.013
Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.013
Prpg1	proline-rich proteoglycan 1	0.013
Thnsl2	threonine synthase-like 2 (S. cerevisiae)	0.013
Tas2r118	taste receptor, type 2, member 118	0.013
Car5a	carbonic anhydrase 5a, mitochondrial	0.013
Pon1	paraoxonase 1	0.013
Srd5a1	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	0.012
Olr1346	olfactory receptor 1346	0.012
Serpina3m	serine (or cysteine) proteinase inhibitor, clade A, member 3M	0.012
Dpyd	dihydropyrimidine dehydrogenase	0.012
Afm	afamin	0.012
Slc27a2	solute carrier family 27 (fatty acid transporter), member 2	0.012
Ugt1a3	UDP glycosyltransferase 1 family, polypeptide A3	0.011
Tdo2	tryptophan 2,3-dioxygenase	0.011
RGD1560925	similar to 2610034M16Rik protein	0.011
Slc10a2	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	0.011
Olr825	olfactory receptor 825	0.011
Dpep1	dipeptidase 1 (renal)	0.011
Il1a	interleukin 1 alpha	0.011
Acsm3	acyl-CoA synthetase medium-chain family member 3	0.011
Cbs	cystathionine beta synthase	0.011
Irgq	immunity-related GTPase family, Q	0.011
Fmo3	flavin containing monooxygenase 3	0.011
Sox13	SRY (sex determining region Y)-box 13	0.011
LOC100361547	Cytochrome P450, family 2, subfamily c, polypeptide 7-like	0.011
Cysltr2	cysteinyl leukotriene receptor 2	0.011
Shank1	SH3 and multiple ankyrin repeat domains 1	0.011
Cml3	camello-like 3	0.011
COX3	cytochrome c oxidase subunit 3	0.011
Ces2c	carboxylesterase 2C	0.010
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.010
Khk	ketohexokinase	0.010