IMP
Process View
leptin mediated signaling pathway
A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "leptin mediated signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Hpca | hippocalcin | 0.085 | ||
| Necab2 | N-terminal EF-hand calcium binding protein 2 | 0.038 | ||
| Cartpt | CART prepropeptide | 0.031 | ||
| Lrrc4b | leucine rich repeat containing 4B | 0.025 | ||
| Lin7b | lin-7 homolog b (C. elegans) | 0.025 | ||
| Syt5 | synaptotagmin V | 0.020 | ||
| Syn2 | synapsin II | 0.017 | ||
| Rap2ip | Rap2 interacting protein | 0.016 | ||
| Atp5h | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d | 0.016 | ||
| Camkv | CaM kinase-like vesicle-associated | 0.015 | ||
| Ctxn1 | cortexin 1 | 0.015 | ||
| Cplx1 | complexin 1 | 0.014 | ||
| Kcnk1 | potassium channel, subfamily K, member 1 | 0.012 | ||
| Snca | synuclein, alpha (non A4 component of amyloid precursor) | 0.012 | ||
| Lpcat4 | lysophosphatidylcholine acyltransferase 4 | 0.012 | ||
| Ndufb9 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9 | 0.012 | ||
| Slc12a5 | solute carrier family 12 (potassium-chloride transporter), member 5 | 0.012 | ||
| Syn1 | synapsin I | 0.012 | ||
| Dbc1 | deleted in bladder cancer 1 (human) | 0.011 | ||
| Syp | synaptophysin | 0.011 | ||
| Tagln3 | transgelin 3 | 0.010 | ||
| Mas1 | MAS1 oncogene | 0.010 | ||
| Hrnbp3 | hexaribonucleotide binding protein 3 | 0.010 | ||
| Nrsn2 | neurensin 2 | 0.010 | ||
| Myt1l | myelin transcription factor 1-like | 0.010 |