IMP
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tolerance induction dependent upon immune response
Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation.
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Click on a gene's description to view its network relationships with genes known to be involved in "tolerance induction dependent upon immune response"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| RT1-EC2 | RT1 class Ib, locus EC2 | 0.989 | ||
| RT1-CE12 | RT1 class I, locus CE12 | 0.513 | ||
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.273 | ||
| Hnf4a | hepatocyte nuclear factor 4, alpha | 0.101 | ||
| Pcdhga11 | protocadherin gamma subfamily A, 11 | 0.093 | ||
| Irf1 | interferon regulatory factor 1 | 0.092 | ||
| RT1-S3 | RT1 class Ib, locus S3 | 0.087 | Rat | |
| Irf7 | interferon regulatory factor 7 | 0.079 | ||
| Gbp2 | guanylate binding protein 2 | 0.074 | ||
| Lgals3bp | lectin, galactoside-binding, soluble, 3 binding protein | 0.072 | ||
| Mpeg1 | macrophage expressed 1 | 0.067 | ||
| Ifi35 | interferon-induced protein 35 | 0.064 | ||
| RT1-N3 | RT1 class Ib, locus N3 | 0.052 | Rat | |
| Casp1 | caspase 1 | 0.052 | ||
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.048 | ||
| Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.046 | ||
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.045 | ||
| Rup2 | urinary protein 2 | 0.045 | ||
| LOC100364352 | cytochrome P450, family 2, subfamily b, polypeptide 9-like | 0.043 | ||
| Fcgr3a | Fc fragment of IgG, low affinity IIIa, receptor | 0.039 | ||
| Myo1a | myosin IA | 0.038 | ||
| LOC100364500 | RT1 class I, locus CE11-like | 0.037 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.037 | ||
| RT1-M3-1 | RT1 class Ib, locus M3, gene 1 | 0.037 | Rat | |
| Nmi | N-myc (and STAT) interactor | 0.036 | ||
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.034 | ||
| Acox3 | acyl-Coenzyme A oxidase 3, pristanoyl | 0.034 | ||
| Otc | ornithine carbamoyltransferase | 0.033 | ||
| Cxcl9 | chemokine (C-X-C motif) ligand 9 | 0.033 | ||
| Gstm2 | glutathione S-transferase mu 2 | 0.032 | ||
| Hal | histidine ammonia lyase | 0.032 | ||
| St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.032 | ||
| Abcg5 | ATP-binding cassette, subfamily G (WHITE), member 5 | 0.032 | ||
| Crtap | cartilage associated protein | 0.031 | ||
| Bst2 | bone marrow stromal cell antigen 2 | 0.031 | ||
| Lgals9 | lectin, galactoside-binding, soluble, 9 | 0.031 | ||
| Mx1 | myxovirus (influenza virus) resistance 1 | 0.031 | ||
| Rsad2 | radical S-adenosyl methionine domain containing 2 | 0.030 | ||
| Igtp | interferon gamma induced GTPase | 0.030 | ||
| LOC100360587 | hypothetical protein LOC100360587 | 0.029 | ||
| Foxc2 | forkhead box C2 | 0.029 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.029 | ||
| Olr1082 | olfactory receptor 1082 | 0.029 | ||
| Cyp2a1 | cytochrome P450, family 2, subfamily a, polypeptide 1 | 0.028 | ||
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.028 | ||
| Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.028 | ||
| Hyal2 | hyaluronoglucosaminidase 2 | 0.027 | ||
| Apol3 | apolipoprotein L, 3 | 0.027 | ||
| Oas1a | 2'-5' oligoadenylate synthetase 1A | 0.027 | ||
| Dtx3l | deltex 3-like (Drosophila) | 0.026 | ||
| Cybb | cytochrome b-245, beta polypeptide | 0.026 | ||
| Slc22a18 | solute carrier family 22, member 18 | 0.025 | ||
| Apoa5 | apolipoprotein A-V | 0.025 | ||
| Kmo | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.025 | ||
| Prokr1 | prokineticin receptor 1 | 0.025 | ||
| Slco2a1 | solute carrier organic anion transporter family, member 2a1 | 0.024 | ||
| Olr1346 | olfactory receptor 1346 | 0.024 | ||
| LOC100364485 | mCG1051031-like | 0.024 | ||
| Foxo3 | forkhead box O3 | 0.023 | ||
| Akap4 | A kinase (PRKA) anchor protein 4 | 0.023 | ||
| Chrm2 | cholinergic receptor, muscarinic 2 | 0.023 | ||
| Itgb5 | integrin, beta 5 | 0.023 | ||
| Tcn2 | transcobalamin 2 | 0.023 | ||
| Mrgprf | MAS-related GPR, member F | 0.022 | ||
| Bmp6 | bone morphogenetic protein 6 | 0.022 | ||
| Cmklr1 | chemokine-like receptor 1 | 0.021 | Rat | |
| Ahr | aryl hydrocarbon receptor | 0.021 | ||
| Cyp2c23 | cytochrome P450, family 2, subfamily c, polypeptide 23 | 0.020 | ||
| Leprot | leptin receptor overlapping transcript | 0.020 | ||
| Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | 0.020 | ||
| Rab20 | RAB20, member RAS oncogene family | 0.020 | ||
| Serping1 | serine (or cysteine) peptidase inhibitor, clade G, member 1 | 0.020 | ||
| Il7 | interleukin 7 | 0.020 | ||
| Cyp2b3 | cytochrome P450, family 2, subfamily b, polypeptide 3 | 0.019 | ||
| RT1-A3 | RT1 class I, locus A3 | 0.019 | ||
| Gnmt | glycine N-methyltransferase | 0.019 | ||
| Ces2c | carboxylesterase 2C | 0.019 | ||
| Dnase1l3 | deoxyribonuclease 1-like 3 | 0.018 | ||
| Mk1 | Mk1 protein | 0.018 | ||
| Olr837 | olfactory receptor 837 | 0.018 | ||
| Gckr | glucokinase (hexokinase 4) regulator | 0.018 | ||
| Ifit3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.018 | ||
| Gbp5 | guanylate binding protein 5 | 0.017 | ||
| Dock8 | dedicator of cytokinesis 8 | 0.017 | ||
| Ugt1a7c | UDP glucuronosyltransferase 1 family, polypeptide A7C | 0.017 | ||
| Tbxa2r | thromboxane A2 receptor | 0.017 | ||
| Tmem176b | transmembrane protein 176B | 0.017 | ||
| Il1rap | interleukin 1 receptor accessory protein | 0.017 | ||
| Cntn5 | contactin 5 | 0.017 | ||
| RT1-CE4 | RT1 class I, locus CE4 | 0.016 | Rat | |
| Cd37 | CD37 molecule | 0.016 | ||
| Prap1 | proline-rich acidic protein 1 | 0.016 | ||
| Ephx1 | epoxide hydrolase 1, microsomal | 0.016 | ||
| Oas1i | 2 ' -5 ' oligoadenylate synthetase 1I | 0.016 | ||
| Vgll2 | vestigial like 2 (Drosophila) | 0.016 | ||
| Ptplad2 | protein tyrosine phosphatase-like A domain containing 2 | 0.016 | ||
| Il12b | interleukin 12B | 0.015 | ||
| RGD1560166 | similar to Probable G-protein coupled receptor 62 (hGPCR8) | 0.015 | ||
| Man2b1 | mannosidase, alpha, class 2B, member 1 | 0.015 | ||
| Stat2 | signal transducer and activator of transcription 2 | 0.015 | ||
| Fcgrt | Fc fragment of IgG, receptor, transporter, alpha | 0.015 | Rat | |
| RT1-CE15 | RT1 class I, locus CE15 | 0.015 | ||
| LOC100365106 | rCG32755-like | 0.015 | ||
| Plbd2 | phospholipase B domain containing 2 | 0.015 | ||
| Gas2l3 | growth arrest-specific 2 like 3 | 0.015 | ||
| Yy1 | YY1 transcription factor | 0.015 | ||
| Hes2 | hairy and enhancer of split 2 (Drosophila) | 0.015 | ||
| RT1-CE2 | RT1 class I, locus CE2 | 0.015 | Rat | |
| Syt8 | synaptotagmin VIII | 0.015 | ||
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.015 | ||
| Slc29a1 | solute carrier family 29 (nucleoside transporters), member 1 | 0.015 | ||
| Fut2 | fucosyltransferase 2 (secretor status included) | 0.015 | ||
| Gpr65 | G-protein coupled receptor 65 | 0.015 | ||
| Slc22a7 | solute carrier family 22 (organic anion transporter), member 7 | 0.015 | ||
| Tap1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.014 | ||
| Sardh | sarcosine dehydrogenase | 0.014 | ||
| Plg | plasminogen | 0.014 | ||
| Serpina1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.014 | ||
| Ton | tonin | 0.014 | ||
| Cmtm4 | CKLF-like MARVEL transmembrane domain containing 4 | 0.014 | ||
| Pde3a | phosphodiesterase 3A, cGMP inhibited | 0.014 | ||
| LOC100362331 | rCG59612-like | 0.014 | ||
| Trim47 | tripartite motif-containing 47 | 0.014 | ||
| Oprd1 | opioid receptor, delta 1 | 0.014 | ||
| Zc3hav1l | zinc finger CCCH-type, antiviral 1-like | 0.014 | ||
| Eif4a1 | eukaryotic translation initiation factor 4A, isoform 1 | 0.014 | ||
| RT1-CE1 | RT1 class I, locus1 | 0.014 | Rat | |
| Serpinb9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.014 | ||
| Parp3 | poly (ADP-ribose) polymerase family, member 3 | 0.014 | ||
| G6pc | glucose-6-phosphatase, catalytic subunit | 0.014 | ||
| C1qa | complement component 1, q subcomponent, A chain | 0.014 | ||
| Pon1 | paraoxonase 1 | 0.013 | ||
| RT1-M6-2 | RT1 class I, locus M6, gene 2 | 0.013 | Rat | |
| Pigr | polymeric immunoglobulin receptor | 0.013 | ||
| Fgf2 | fibroblast growth factor 2 | 0.013 | ||
| Cyp2b15 | cytochrome P450, family 2, subfamily b, polypeptide 15 | 0.013 | ||
| Padi1 | peptidyl arginine deiminase, type I | 0.013 | ||
| Asgr2 | asialoglycoprotein receptor 2 | 0.013 | ||
| Gja3 | gap junction protein, alpha 3 | 0.013 | ||
| Hspb9 | heat shock protein, alpha-crystallin-related, B9 | 0.013 | ||
| Egfl7 | EGF-like-domain, multiple 7 | 0.013 | ||
| Slc11a1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.013 | ||
| RT1-Cl | RT1 class Ib, locus Cl | 0.013 | ||
| Ccl5 | chemokine (C-C motif) ligand 5 | 0.013 | ||
| Ilvbl | ilvB (bacterial acetolactate synthase)-like | 0.013 | ||
| Slco2b1 | solute carrier organic anion transporter family, member 2b1 | 0.013 | ||
| Uba7 | ubiquitin-like modifier activating enzyme 7 | 0.013 | ||
| Entpd1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.013 | ||
| Glp1r | glucagon-like peptide 1 receptor | 0.013 | ||
| Akr1c14 | aldo-keto reductase family 1, member C14 | 0.013 | ||
| Kcne1 | potassium voltage-gated channel, Isk-related family, member 1 | 0.013 | ||
| Aldh3a1 | aldehyde dehydrogenase 3 family, member A1 | 0.012 | ||
| Trim5 | tripartite motif-containing 5 | 0.012 | ||
| Crybb2 | crystallin, beta B2 | 0.012 | ||
| Slfn3 | schlafen 3 | 0.012 | ||
| Dhx58 | DEXH (Asp-Glu-X-His) box polypeptide 58 | 0.012 | ||
| Asah1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 0.012 | ||
| Cdh8 | cadherin 8 | 0.012 | ||
| Ucn | urocortin | 0.012 | ||
| Spi1 | spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 0.012 | ||
| Pla2g7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.012 | ||
| Pde6h | phosphodiesterase 6H, cGMP-specific, cone, gamma | 0.012 | ||
| Np | nucleoside phosphorylase | 0.012 | ||
| Fxyd1 | FXYD domain-containing ion transport regulator 1 | 0.012 | ||
| Ctsh | cathepsin H | 0.012 | ||
| Irf8 | interferon regulatory factor 8 | 0.012 | ||
| C2 | complement component 2 | 0.012 | ||
| P2rx7 | purinergic receptor P2X, ligand-gated ion channel, 7 | 0.012 | ||
| RT1-T24-1 | RT1 class I, locus T24, gene 1 | 0.012 | Rat | |
| LOC502825 | hypothetical LOC502825 | 0.012 | ||
| Mocs3 | molybdenum cofactor synthesis 3 | 0.012 | ||
| Dmgdh | dimethylglycine dehydrogenase | 0.012 | ||
| Gpr116 | G protein-coupled receptor 116 | 0.012 | ||
| Dmbt1 | deleted in malignant brain tumors 1 | 0.011 | ||
| Sult1e1 | sulfotransferase family 1E, estrogen-preferring, member 1 | 0.011 | ||
| RGD1306526 | hypothetical LOC310764 | 0.011 | ||
| Bend7 | BEN domain containing 7 | 0.011 | ||
| Dbh | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 0.011 | ||
| Insl3 | insulin-like 3 | 0.011 | ||
| Asgr1 | asialoglycoprotein receptor 1 | 0.011 | ||
| Cd300lf | CD300 molecule-like family member f | 0.011 | ||
| Phactr2 | phosphatase and actin regulator 2 | 0.011 | ||
| Atp1a4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.011 | ||
| Cyp7a1 | cytochrome P450, family 7, subfamily a, polypeptide 1 | 0.011 | ||
| Ankrd2 | ankyrin repeat domain 2 (stretch responsive muscle) | 0.011 | ||
| Twist2 | twist homolog 2 (Drosophila) | 0.011 | ||
| Hpn | hepsin | 0.011 | ||
| Tmem176a | transmembrane protein 176A | 0.011 | ||
| Oasl2 | 2'-5' oligoadenylate synthetase-like 2 | 0.011 | ||
| Sox17 | SRY (sex determining region Y)-box 17 | 0.011 | ||
| Itgam | integrin, alpha M | 0.011 | ||
| Trim17 | tripartite motif-containing 17 | 0.011 | ||
| Fabp2 | fatty acid binding protein 2, intestinal | 0.011 | ||
| Cyth4 | cytohesin 4 | 0.011 | ||
| Acvr1b | activin A receptor, type IB | 0.011 | ||
| Cyba | cytochrome b-245, alpha polypeptide | 0.011 | ||
| Tapbp | TAP binding protein | 0.011 | ||
| Tapbpl | TAP binding protein-like | 0.011 | ||
| Aif1 | allograft inflammatory factor 1 | 0.011 | ||
| Amy2 | amylase 2, pancreatic | 0.011 | ||
| Ifi44l | interferon-induced protein 44-like | 0.011 | ||
| Cd200r1 | CD200 receptor 1 | 0.010 | ||
| Sh3pxd2a | SH3 and PX domains 2A | 0.010 | ||
| Cx3cr1 | chemokine (C-X3-C motif) receptor 1 | 0.010 | ||
| LOC100360403 | ATP-binding cassette, sub-family C, member 9-like | 0.010 | ||
| A1i3 | alpha-1-inhibitor III | 0.010 | ||
| Tspan4 | tetraspanin 4 | 0.010 | ||
| RT1-CE10 | RT1 class I, locus CE10 | 0.010 | Rat | |
| Gpx3 | glutathione peroxidase 3 | 0.010 | ||
| Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.010 | ||
| Gimap8 | GTPase, IMAP family member 8 | 0.010 | ||
| Dffb | DNA fragmentation factor, beta polypeptide (caspase-activated DNase) | 0.010 | ||
| Dnah8 | dynein, axonemal, heavy chain 8 | 0.010 | ||
| Cdx1 | caudal type homeo box 1 | 0.010 | ||
| Tnfsf10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.010 | ||
| Slc7a2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.010 | ||
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.010 | ||
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.010 | ||
| Gper | G protein-coupled estrogen receptor 1 | 0.010 | ||
| Smcp | sperm mitochondria-associated cysteine-rich protein | 0.010 | ||
| Ttc30a1 | tetratricopeptide repeat domain 30A1 | 0.010 |