IMP
Process View
activation of cysteine type endopeptidase activity involved in apoptotic process
Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.
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Click on a gene's description to view its network relationships with genes known to be involved in "activation of cysteine type endopeptidase activity involved in apoptotic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Jak1 | Janus kinase 1 | 0.034 | ||
| Smad1 | SMAD family member 1 | 0.025 | Rat | |
| Psmd2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.021 | ||
| Cyc1 | cytochrome c-1 | 0.018 | ||
| Vegfa | vascular endothelial growth factor A | 0.018 | ||
| Cebpd | CCAAT/enhancer binding protein (C/EBP), delta | 0.017 | ||
| Rpn2 | ribophorin II | 0.017 | ||
| Impdh2 | IMP (inosine monophosphate) dehydrogenase 2 | 0.017 | ||
| Syt4 | synaptotagmin IV | 0.017 | ||
| Zfp36 | zinc finger protein 36 | 0.017 | ||
| Slc25a3 | solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 | 0.017 | ||
| Dlst | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.016 | ||
| Pkia | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.016 | ||
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.016 | ||
| Casp3 | caspase 3 | 0.016 | ||
| Pde4d | phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) | 0.016 | ||
| Fuca1 | fucosidase, alpha-L- 1, tissue | 0.016 | ||
| Jun | Jun oncogene | 0.015 | ||
| Nek9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.015 | ||
| Socs3 | suppressor of cytokine signaling 3 | 0.015 | ||
| Il6 | interleukin 6 | 0.015 | ||
| Creb1 | cAMP responsive element binding protein 1 | 0.014 | ||
| Mmp8 | matrix metallopeptidase 8 | 0.014 | ||
| Cplx1 | complexin 1 | 0.014 | ||
| Acvr1 | activin A receptor, type I | 0.014 | ||
| Tars | threonyl-tRNA synthetase | 0.014 | ||
| Pgk1 | phosphoglycerate kinase 1 | 0.014 | ||
| Cyb5r1 | cytochrome b5 reductase 1 | 0.014 | ||
| Cd38 | CD38 molecule | 0.013 | ||
| Map4k4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.013 | ||
| Pawr | PRKC, apoptosis, WT1, regulator | 0.013 | ||
| Ssrp1 | structure specific recognition protein 1 | 0.013 | ||
| Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.013 | ||
| Zfp36l1 | zinc finger protein 36, C3H type-like 1 | 0.013 | ||
| Tgfbr3 | transforming growth factor, beta receptor III | 0.013 | ||
| Top2b | topoisomerase (DNA) II beta | 0.013 | ||
| Ppard | peroxisome proliferator-activated receptor delta | 0.013 | ||
| Cct4 | chaperonin containing Tcp1, subunit 4 (delta) | 0.013 | ||
| Snrk | SNF related kinase | 0.013 | ||
| Hspa8 | heat shock protein 8 | 0.013 | ||
| Ckmt1 | creatine kinase, mitochondrial 1 | 0.013 | ||
| Tlr4 | toll-like receptor 4 | 0.013 | ||
| Atp6v1b2 | ATPase, H transporting, lysosomal V1 subunit B2 | 0.013 | ||
| Pla2g4a | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.013 | ||
| Map3k1 | mitogen activated protein kinase kinase kinase 1 | 0.013 | ||
| Cyp4b1 | cytochrome P450, family 4, subfamily b, polypeptide 1 | 0.013 | ||
| Wdr26 | WD repeat domain 26 | 0.013 | ||
| Lig3 | ligase III, DNA, ATP-dependent | 0.012 | ||
| Il2rb | interleukin 2 receptor, beta | 0.012 | ||
| Irak3 | interleukin-1 receptor-associated kinase 3 | 0.012 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.012 | ||
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.012 | ||
| Bcl2l1 | Bcl2-like 1 | 0.012 | ||
| Slc2a3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.012 | ||
| Cd14 | CD14 molecule | 0.012 | ||
| Gadd45a | growth arrest and DNA-damage-inducible, alpha | 0.012 | ||
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.012 | ||
| Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.012 | ||
| Nat1 | N-acetyltransferase 1 | 0.012 | ||
| Ralb | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | 0.012 | ||
| Bcl2l2 | Bcl2-like 2 | 0.012 | ||
| Rgs3 | regulator of G-protein signaling 3 | 0.012 | ||
| Enpp3 | ectonucleotide pyrophosphatase/phosphodiesterase 3 | 0.012 | ||
| Csnk1g1 | casein kinase 1, gamma 1 | 0.012 | ||
| Prrx1 | paired related homeobox 1 | 0.012 | ||
| Casp2 | caspase 2 | 0.012 | Fly | |
| Il1r1 | interleukin 1 receptor, type I | 0.012 | ||
| Nxph4 | neurexophilin 4 | 0.012 | ||
| B2m | beta-2 microglobulin | 0.012 | ||
| Myo1b | myosin Ib | 0.012 | ||
| Cd247 | Cd247 molecule | 0.012 | ||
| Htr1b | 5-hydroxytryptamine (serotonin) receptor 1B | 0.012 | ||
| Hdlbp | high density lipoprotein binding protein | 0.012 | ||
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.012 | ||
| Gfi1 | growth factor independent 1 transcription repressor | 0.011 | ||
| Hexa | hexosaminidase A | 0.011 | ||
| Calcrl | calcitonin receptor-like | 0.011 | ||
| Slfn2 | schlafen 2 | 0.011 | ||
| Gmeb2 | glucocorticoid modulatory element binding protein 2 | 0.011 | ||
| Tgfbr1 | transforming growth factor, beta receptor 1 | 0.011 | ||
| Smc1a | structural maintenance of chromosomes 1A | 0.011 | ||
| Prkch | protein kinase C, eta | 0.011 | ||
| Chd6 | chromodomain helicase DNA binding protein 6 | 0.011 | ||
| Gabrb1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 | 0.011 | ||
| Icos | inducible T-cell co-stimulator | 0.011 | ||
| Eif3f | eukaryotic translation initiation factor 3, subunit F | 0.011 | ||
| Cct7 | chaperonin containing Tcp1, subunit 7 (eta) | 0.011 | ||
| Adar | adenosine deaminase, RNA-specific | 0.011 | ||
| Xdh | xanthine dehydrogenase | 0.011 | Human | |
| Srgn | serglycin | 0.011 | ||
| Max | MYC associated factor X | 0.011 | ||
| Adm | adrenomedullin | 0.011 | ||
| Tmpo | thymopoietin | 0.011 | ||
| Sfrp4 | secreted frizzled-related protein 4 | 0.011 | ||
| Rpl22 | ribosomal protein L22 | 0.011 | ||
| LOC313672 | kazrin | 0.011 | ||
| Cxcl1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.011 | ||
| Gja3 | gap junction protein, alpha 3 | 0.011 | ||
| Cish | cytokine inducible SH2-containing protein | 0.011 | ||
| RT1-A3 | RT1 class I, locus A3 | 0.011 | ||
| Rasgrp1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.011 | ||
| Il1b | interleukin 1 beta | 0.011 | ||
| Il1rap | interleukin 1 receptor accessory protein | 0.011 | ||
| Cdkn2b | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 0.011 | ||
| Ss18 | synovial sarcoma translocation, Chromosome 18 | 0.011 | ||
| Itpr2 | inositol 1,4,5-triphosphate receptor, type 2 | 0.011 | ||
| C1s | complement component 1, s subcomponent | 0.011 | ||
| Usp3 | ubiquitin specific peptidase 3 | 0.011 | ||
| Clec10a | C-type lectin domain family 10, member A | 0.011 | ||
| Il15 | interleukin 15 | 0.011 | ||
| Acap1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 | 0.011 | ||
| Hspa1a | heat shock 70kD protein 1A | 0.011 | ||
| Rab20 | RAB20, member RAS oncogene family | 0.010 | ||
| Hsph1 | heat shock 105/110 protein 1 | 0.010 | ||
| Map6 | microtubule-associated protein 6 | 0.010 | ||
| RGD1565591 | similar to Ski protein | 0.010 | ||
| Dd25 | hypothetical protein Dd25 | 0.010 | ||
| Stfa2l3 | stefin A2-like 3 | 0.010 | ||
| Ifitm3 | interferon induced transmembrane protein 3 | 0.010 | ||
| Stx6 | syntaxin 6 | 0.010 | ||
| Tex10 | testis expressed 10 | 0.010 | ||
| Adam17 | ADAM metallopeptidase domain 17 | 0.010 | ||
| Ceacam10 | carcinoembryonic antigen-related cell adhesion molecule 10 | 0.010 | ||
| Nrg2 | neuregulin 2 | 0.010 | ||
| Hes2 | hairy and enhancer of split 2 (Drosophila) | 0.010 | ||
| Ntn1 | netrin 1 | 0.010 | ||
| Kcnk1 | potassium channel, subfamily K, member 1 | 0.010 | ||
| Txnrd1 | thioredoxin reductase 1 | 0.010 | ||
| Sh2b3 | SH2B adaptor protein 3 | 0.010 | ||
| Hand2 | heart and neural crest derivatives expressed 2 | 0.010 | ||
| Cd46 | CD46 molecule, complement regulatory protein | 0.010 | ||
| Hsp90ab1 | heat shock protein 90 alpha (cytosolic), class B member 1 | 0.010 | ||
| Cd53 | Cd53 molecule | 0.010 | ||
| Cyth1 | cytohesin 1 | 0.010 | ||
| Smad2 | SMAD family member 2 | 0.010 | Rat | |
| Btg2 | BTG family, member 2 | 0.010 | ||
| Adcy5 | adenylate cyclase 5 | 0.010 | ||
| Mgst2 | microsomal glutathione S-transferase 2 | 0.010 | ||
| Rpa2 | replication protein A2 | 0.010 | ||
| Lhx1 | LIM homeobox 1 | 0.010 | ||
| Wrnip1 | Werner helicase interacting protein 1 | 0.010 | ||
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.010 | ||
| Sepp1 | selenoprotein P, plasma, 1 | 0.010 | ||
| Plekha1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.010 | ||
| Errfi1 | ERBB receptor feedback inhibitor 1 | 0.010 | ||
| Btnl1 | butyrophilin-like 1 | 0.010 | ||
| Nsfl1c | NSFL1 (p97) cofactor (p47) | 0.010 | ||
| Hsd11b1 | hydroxysteroid 11-beta dehydrogenase 1 | 0.010 | ||
| Apex1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 0.010 | ||
| Klf4 | Kruppel-like factor 4 (gut) | 0.010 | ||
| Trdmt1 | tRNA aspartic acid methyltransferase 1 | 0.010 |