IMP: Integrative Multi-species Prediction

Rattus norvegicus

19 genes annotated in rat

autophagy

The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.

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In addition to gene-name show these genes:

Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "autophagy"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "autophagy" (in gray)

Name	Description	Probability	Func Analog Organism
Tmbim6	transmembrane BAX inhibitor motif containing 6	0.275
St13	suppression of tumorigenicity 13	0.174
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform	0.162
Eef2	eukaryotic translation elongation factor 2	0.124
Jak1	Janus kinase 1	0.105
Arf1	ADP-ribosylation factor 1	0.085
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.082
Ctsl1	cathepsin L1	0.060
Ctsd	cathepsin D	0.050
Map2k1	mitogen activated protein kinase kinase 1	0.048	Yeast
Ubqln1	ubiquilin 1	0.044
Ptov1	prostate tumor overexpressed 1	0.042
Cyth1	cytohesin 1	0.041
Atp6v1b2	ATPase, H transporting, lysosomal V1 subunit B2	0.041
Ube2g1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.034
Taf10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.034
Strap	serine/threonine kinase receptor associated protein	0.034
Trim23	tripartite motif-containing 23	0.031
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.030
Pdp1	pyruvate dehyrogenase phosphatase catalytic subunit 1	0.030
Fbxo3	F-box protein 3	0.029
Rab1b	RAB1B, member RAS oncogene family	0.028	Human
Casp3	caspase 3	0.028
Grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.027
Ghitm	growth hormone inducible transmembrane protein	0.026
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.026
Akt2	v-akt murine thymoma viral oncogene homolog 2	0.025	Yeast
Rab5a	RAB5A, member RAS oncogene family	0.025
Stxbp3	syntaxin binding protein 3	0.024
Gja1	gap junction protein, alpha 1	0.024
Syngr2	synaptogyrin 2	0.024
LOC362855	P55	0.023
Zfand6	zinc finger, AN1-type domain 6	0.023
Usf2	upstream transcription factor 2, c-fos interacting	0.022
Hbp1	HMG-box transcription factor 1	0.021
Psap	prosaposin	0.021
Dcaf7	DDB1 and CUL4 associated factor 7	0.020
Morf4l2	mortality factor 4 like 2	0.020
Cdc37	cell division cycle 37 homolog (S. cerevisiae)	0.020
Cacnb3	calcium channel, voltage-dependent, beta 3 subunit	0.020
Rab11a	RAB11a, member RAS oncogene family	0.020
Glul	glutamate-ammonia ligase (glutamine synthetase)	0.020
Ftl	ferritin, light polypeptide	0.019
Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isoform	0.018	Fly
Ppp2r2a	protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform	0.018
LOC100364212	heterogeneous nuclear ribonucleoprotein K-like	0.018
Snx4	sorting nexin 4	0.017	Yeast
Cript	cysteine-rich PDZ-binding protein	0.017
Bnip3l	BCL2/adenovirus E1B interacting protein 3-like	0.017
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform	0.017
Tm9sf4	transmembrane 9 superfamily protein member 4	0.017
Cox8a	cytochrome c oxidase subunit VIIIa	0.017
Dnaja2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.017
Chd6	chromodomain helicase DNA binding protein 6	0.016
Dnm1l	dynamin 1-like	0.016
Ube2b	ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae)	0.016	Fly
Ccr1	chemokine (C-C motif) receptor 1	0.016
Pdia3	protein disulfide isomerase family A, member 3	0.015
Bet1	blocked early in transport 1 homolog (S. cerevisiae)	0.015
Papss1	3'-phosphoadenosine 5'-phosphosulfate synthase 1	0.015
Ap2s1	adaptor-related protein complex 2, sigma 1 subunit	0.014
Ptprc	protein tyrosine phosphatase, receptor type, C	0.014
Flcn	folliculin	0.014
Foxd4	forkhead box D4	0.014
Jtb	jumping translocation breakpoint	0.014
Vdac1	voltage-dependent anion channel 1	0.014
Rab4a	RAB4A, member RAS oncogene family	0.014
Nmt1	N-myristoyltransferase 1	0.014
Lifr	leukemia inhibitory factor receptor alpha	0.013
Mapk6	mitogen-activated protein kinase 6	0.013
Copb1	coatomer protein complex, subunit beta 1	0.013
Vegfa	vascular endothelial growth factor A	0.013
Dag1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.013
P4hb	prolyl 4-hydroxylase, beta polypeptide	0.013
Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform	0.013
Adar	adenosine deaminase, RNA-specific	0.013
Akap1	A kinase (PRKA) anchor protein 1	0.013
Snap23	synaptosomal-associated protein 23	0.013
Hist1h1a	histone cluster 1, H1a	0.013
Ptpn18	protein tyrosine phosphatase, non-receptor type 18	0.013
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.012
Ube2a	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.012
Calm3	calmodulin 3	0.012
Cnbp	CCHC-type zinc finger, nucleic acid binding protein	0.012
Sqstm1	sequestosome 1	0.012	Human
Rab11b	RAB11B, member RAS oncogene family	0.012
Psmd2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.012
Ensa	endosulfine alpha	0.012
Gnb2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.012
Gria2	glutamate receptor, ionotropic, AMPA 2	0.012
Sgta	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.012
Cyfip2	cytoplasmic FMR1 interacting protein 2	0.012
Camk4	calcium/calmodulin-dependent protein kinase IV	0.012
Ngly1	N-glycanase 1	0.012
Ndfip2	Nedd4 family interacting protein 2	0.012
Arl11	ADP-ribosylation factor-like 11	0.011
Snx3	sorting nexin 3	0.011
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.011
Scamp1	secretory carrier membrane protein 1	0.011
Dctn1	dynactin 1	0.011
Rpn2	ribophorin II	0.011
Cdc34	cell division cycle 34 homolog (S. cerevisiae)	0.011
Pik3r2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.011	Human
Sepw1	selenoprotein W, 1	0.011
Phc1	polyhomeotic homolog 1 (Drosophila)	0.011
Prkacb	protein kinase, cAMP dependent, catalytic, beta	0.011
Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	0.011
Il18	interleukin 18	0.011
Tkt	transketolase	0.011
Bap1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	0.010
Arf3	ADP-ribosylation factor 3	0.010
Zfp260	zinc finger protein 260	0.010
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.010
Synrg	synergin, gamma	0.010
Prdx6	peroxiredoxin 6	0.010
Ehd1	EH-domain containing 1	0.010
Sort1	sortilin 1	0.010