IMP
Process View
er associated ubiquitin dependent protein catabolic process
The chemical reactions and pathways resulting in the breakdown of proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation. This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "er associated ubiquitin dependent protein catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Hspa5 | heat shock protein 5 | 0.894 | Yeast | |
| Hsph1 | heat shock 105/110 protein 1 | 0.715 | ||
| Creld2 | cysteine-rich with EGF-like domains 2 | 0.409 | ||
| Pdia4 | protein disulfide isomerase family A, member 4 | 0.394 | ||
| Dnajb11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.369 | ||
| Chordc1 | cysteine and histidine-rich domain (CHORD)-containing 1 | 0.330 | ||
| Dnaja1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.301 | Yeast | |
| Pdia6 | protein disulfide isomerase family A, member 6 | 0.273 | ||
| Canx | calnexin | 0.200 | ||
| Manf | mesencephalic astrocyte-derived neurotrophic factor | 0.162 | ||
| Hsp90b1 | heat shock protein 90, beta, member 1 | 0.157 | Human | |
| Hsp90aa1 | heat shock protein 90, alpha (cytosolic), class A member 1 | 0.143 | ||
| Pdia3 | protein disulfide isomerase family A, member 3 | 0.102 | ||
| Hspd1 | heat shock protein 1 (chaperonin) | 0.100 | ||
| Dnajb9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.098 | Human Mouse | |
| Dnajc3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.085 | ||
| Sec61a1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.083 | ||
| Ptges3 | prostaglandin E synthase 3 (cytosolic) | 0.072 | ||
| Calr | calreticulin | 0.072 | ||
| Lrrc59 | leucine rich repeat containing 59 | 0.057 | ||
| Hprt1 | hypoxanthine phosphoribosyltransferase 1 | 0.052 | ||
| Mgat2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 0.050 | ||
| Txnl1 | thioredoxin-like 1 | 0.040 | ||
| St13 | suppression of tumorigenicity 13 | 0.039 | ||
| Cand1 | cullin-associated and neddylation-dissociated 1 | 0.038 | ||
| Stip1 | stress-induced phosphoprotein 1 | 0.037 | ||
| Ppp1cb | protein phosphatase 1, catalytic subunit, beta isoform | 0.032 | ||
| Slc35b1 | solute carrier family 35, member B1 | 0.028 | ||
| Sel1l | sel-1 suppressor of lin-12-like (C. elegans) | 0.027 | ||
| Spcs2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.025 | ||
| Hyou1 | hypoxia up-regulated 1 | 0.024 | ||
| Serp1 | stress-associated endoplasmic reticulum protein 1 | 0.021 | ||
| Eif4e | eukaryotic translation initiation factor 4E | 0.019 | ||
| Ubc | ubiquitin C | 0.019 | ||
| Mospd3 | motile sperm domain containing 3 | 0.018 | ||
| Brcc3 | BRCA1/BRCA2-containing complex, subunit 3 | 0.018 | ||
| RGD1309748 | similar to CG4768-PA | 0.018 | ||
| Spcs3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 0.017 | ||
| Dusp11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 0.016 | ||
| Eif4a2 | eukaryotic translation initiation factor 4A, isoform 2 | 0.016 | ||
| Akap11 | A kinase (PRKA) anchor protein 11 | 0.016 | ||
| Tob1 | transducer of ErbB-2.1 | 0.016 | ||
| Slc30a5 | solute carrier family 30 (zinc transporter), member 5 | 0.016 | ||
| Dnajb1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.016 | ||
| Hspa8 | heat shock protein 8 | 0.016 | ||
| Hint2 | histidine triad nucleotide binding protein 2 | 0.015 | ||
| Hspa1a | heat shock 70kD protein 1A | 0.015 | ||
| Uso1 | USO1 homolog, vesicle docking protein (yeast) | 0.015 | ||
| Cltc | clathrin, heavy chain (Hc) | 0.014 | ||
| Xbp1 | X-box binding protein 1 | 0.014 | ||
| Os9 | osteosarcoma amplified 9 | 0.013 | ||
| Arfgap3 | ADP-ribosylation factor GTPase activating protein 3 | 0.013 | ||
| Rrbp1 | ribosome binding protein 1 | 0.013 | ||
| Rnf146 | ring finger protein 146 | 0.013 | ||
| Tor1aip2 | torsin A interacting protein 2 | 0.013 | ||
| Morf4l2 | mortality factor 4 like 2 | 0.013 | ||
| Copb2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.013 | ||
| Gpr89 | G protein-coupled receptor 89 | 0.013 | ||
| Mtmr4 | myotubularin related protein 4 | 0.013 | ||
| Rnf181 | ring finger protein 181 | 0.013 | ||
| Nploc4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.013 | ||
| Tcp11l2 | t-complex 11 (mouse) like 2 | 0.012 | ||
| Uba5 | ubiquitin-like modifier activating enzyme 5 | 0.012 | ||
| Ccdc47 | coiled-coil domain containing 47 | 0.012 | ||
| Mapk6 | mitogen-activated protein kinase 6 | 0.012 | ||
| Azi2 | 5-azacytidine induced 2 | 0.011 | ||
| Tmem49 | transmembrane protein 49 | 0.011 | ||
| Ppp2ca | protein phosphatase 2, catalytic subunit, alpha isoform | 0.011 | ||
| Ppm1a | protein phosphatase 1A, magnesium dependent, alpha isoform | 0.011 | ||
| Ddost | dolichyl-diphosphooligosaccharide-protein glycosyltransferase | 0.011 | ||
| Ift20 | intraflagellar transport 20 homolog (Chlamydomonas) | 0.011 | ||
| Fam18b2 | family with sequence similarity 18, member B2 | 0.011 | ||
| Sumo1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.011 | ||
| Suds3 | suppressor of defective silencing 3 homolog (S. cerevisiae) | 0.010 | ||
| Azin1 | antizyme inhibitor 1 | 0.010 | ||
| Tomm70a | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) | 0.010 |