IMP
Process View
cartilage development
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cartilage development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Col1a1 | collagen, type I, alpha 1 | 0.924 | Mouse Rat | |
| Col3a1 | collagen, type III, alpha 1 | 0.905 | Rat | |
| Col1a2 | collagen, type I, alpha 2 | 0.811 | Rat | |
| Vim | vimentin | 0.786 | ||
| Bgn | biglycan | 0.756 | Rat | |
| Col5a2 | collagen, type V, alpha 2 | 0.557 | Rat | |
| Lum | lumican | 0.510 | ||
| Col12a1 | collagen, type XII, alpha 1 | 0.317 | ||
| Dcn | decorin | 0.284 | Zebrafish Rat | |
| Col5a1 | collagen, type V, alpha 1 | 0.246 | Rat | |
| Eln | elastin | 0.234 | ||
| Fn1 | fibronectin 1 | 0.234 | ||
| Dab2 | disabled homolog 2 (Drosophila) | 0.131 | ||
| Loxl1 | lysyl oxidase-like 1 | 0.093 | ||
| Shox2 | short stature homeobox 2 | 0.080 | Mouse | |
| Lox | lysyl oxidase | 0.078 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.073 | Mouse | |
| Anxa1 | annexin A1 | 0.070 | ||
| Mfap4 | microfibrillar-associated protein 4 | 0.064 | ||
| Col4a5 | collagen, type IV, alpha 5 | 0.055 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.051 | ||
| Lamc1 | laminin, gamma 1 | 0.049 | ||
| Nr1d2 | nuclear receptor subfamily 1, group D, member 2 | 0.045 | ||
| Hapln1 | hyaluronan and proteoglycan link protein 1 | 0.043 | Rat | |
| Pcolce | procollagen C-endopeptidase enhancer | 0.042 | ||
| Col15a1 | collagen, type XV, alpha 1 | 0.041 | ||
| Tgfb3 | transforming growth factor, beta 3 | 0.041 | Zebrafish | |
| Nup153 | nucleoporin 153 | 0.041 | ||
| Srpx | sushi-repeat-containing protein, X-linked | 0.039 | ||
| Dbp | D site of albumin promoter (albumin D-box) binding protein | 0.038 | ||
| Sod3 | superoxide dismutase 3, extracellular | 0.038 | ||
| Aldh6a1 | aldehyde dehydrogenase 6 family, member A1 | 0.037 | ||
| Irs1 | insulin receptor substrate 1 | 0.037 | ||
| Col9a1 | collagen, type IX, alpha 1 | 0.037 | ||
| Fbn1 | fibrillin 1 | 0.036 | ||
| Aspn | asporin | 0.036 | ||
| Ece1 | endothelin converting enzyme 1 | 0.036 | ||
| Kcnc3 | potassium voltage gated channel, Shaw-related subfamily, member 3 | 0.036 | ||
| Gpr176 | G protein-coupled receptor 176 | 0.036 | ||
| Igfbp5 | insulin-like growth factor binding protein 5 | 0.035 | ||
| Ctdsp1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | 0.034 | ||
| Ankrd1 | ankyrin repeat domain 1 (cardiac muscle) | 0.034 | ||
| Postn | periostin, osteoblast specific factor | 0.033 | Rat | |
| Atp1b2 | ATPase, Na+/K+ transporting, beta 2 polypeptide | 0.033 | ||
| Hoxc4 | homeo box C4 | 0.033 | Mouse | |
| Chad | chondroadherin | 0.031 | ||
| Angptl2 | angiopoietin-like 2 | 0.031 | ||
| Rara | retinoic acid receptor, alpha | 0.030 | Rat | |
| Smad6 | SMAD family member 6 | 0.030 | ||
| Ralgds | ral guanine nucleotide dissociation stimulator | 0.029 | ||
| Col6a2 | collagen, type VI, alpha 2 | 0.029 | ||
| Gja1 | gap junction protein, alpha 1 | 0.029 | ||
| Map3k3 | mitogen activated protein kinase kinase kinase 3 | 0.028 | ||
| Aebp1 | AE binding protein 1 | 0.028 | ||
| Ctsk | cathepsin K | 0.028 | ||
| S1pr2 | sphingosine-1-phosphate receptor 2 | 0.028 | ||
| P2rx3 | purinergic receptor P2X, ligand-gated ion channel, 3 | 0.027 | ||
| Lrpap1 | low density lipoprotein receptor-related protein associated protein 1 | 0.027 | ||
| RGD1305645 | similar to RIKEN cDNA 1500015O10 | 0.027 | ||
| Col2a1 | collagen, type II, alpha 1 | 0.027 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.026 | ||
| C1qtnf6 | C1q and tumor necrosis factor related protein 6 | 0.026 | ||
| Cpz | carboxypeptidase Z | 0.025 | ||
| Palm | paralemmin | 0.025 | ||
| Sox17 | SRY (sex determining region Y)-box 17 | 0.025 | ||
| Mgp | matrix Gla protein | 0.024 | ||
| Sox10 | SRY (sex determining region Y)-box 10 | 0.023 | ||
| Sdc2 | syndecan 2 | 0.023 | ||
| Ccnd3 | cyclin D3 | 0.022 | ||
| Nbl1 | neuroblastoma, suppression of tumorigenicity 1 | 0.022 | ||
| Esr1 | estrogen receptor 1 | 0.022 | Rat | |
| Col8a1 | collagen, type VIII, alpha 1 | 0.022 | ||
| Sdc3 | syndecan 3 | 0.021 | ||
| Lect1 | leukocyte cell derived chemotaxin 1 | 0.021 | ||
| Foxd4 | forkhead box D4 | 0.021 | ||
| Bmp6 | bone morphogenetic protein 6 | 0.021 | ||
| Scarf2 | scavenger receptor class F, member 2 | 0.021 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.021 | ||
| Glt25d1 | glycosyltransferase 25 domain containing 1 | 0.020 | ||
| Syn3 | synapsin III | 0.020 | ||
| Vcan | versican | 0.020 | ||
| Cyb5r1 | cytochrome b5 reductase 1 | 0.019 | ||
| Ar | androgen receptor | 0.019 | ||
| Fzd2 | frizzled homolog 2 (Drosophila) | 0.019 | ||
| Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.019 | ||
| Fgfr1 | Fibroblast growth factor receptor 1 | 0.019 | Mouse | |
| Tgfbr3 | transforming growth factor, beta receptor III | 0.019 | ||
| Psen1 | presenilin 1 | 0.019 | ||
| Tpo | thyroid peroxidase | 0.019 | ||
| Zyx | zyxin | 0.019 | ||
| Unc5b | unc-5 homolog B (C. elegans) | 0.019 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.018 | Human Mouse | |
| Gpx3 | glutathione peroxidase 3 | 0.018 | ||
| Foxe3 | forkhead box E3 | 0.018 | ||
| Hapln4 | hyaluronan and proteoglycan link protein 4 | 0.018 | ||
| Grin2c | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | 0.018 | ||
| Mag | myelin-associated glycoprotein | 0.018 | ||
| Ptbp1 | polypyrimidine tract binding protein 1 | 0.018 | ||
| Ccdc80 | coiled-coil domain containing 80 | 0.017 | ||
| LOC100360403 | ATP-binding cassette, sub-family C, member 9-like | 0.017 | ||
| Mmp23 | matrix metallopeptidase 23 | 0.017 | ||
| Omp | olfactory marker protein | 0.017 | ||
| Myh9 | myosin, heavy chain 9, non-muscle | 0.017 | ||
| Dmd | dystrophin | 0.016 | ||
| Cyp1b1 | cytochrome P450, family 1, subfamily b, polypeptide 1 | 0.016 | ||
| Prrx1 | paired related homeobox 1 | 0.016 | Mouse | |
| Hoxd3 | homeo box D3 | 0.016 | Mouse | |
| Clu | clusterin | 0.016 | ||
| Lphn1 | latrophilin 1 | 0.016 | ||
| Myl9 | myosin, light chain 9, regulatory | 0.016 | ||
| Grin3a | glutamate receptor, ionotropic, N-methyl-D-aspartate 3A | 0.016 | ||
| Ddr2 | discoidin domain receptor tyrosine kinase 2 | 0.016 | ||
| Nfia | nuclear factor I/A | 0.016 | ||
| Pgcp | plasma glutamate carboxypeptidase | 0.016 | ||
| Scn4a | sodium channel, voltage-gated, type IV, alpha subunit | 0.016 | ||
| Leprel2 | leprecan-like 2 | 0.016 | ||
| Mybph | myosin binding protein H | 0.015 | ||
| Cel | carboxyl ester lipase | 0.015 | ||
| Cntn2 | contactin 2 (axonal) | 0.015 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.015 | ||
| Casp3 | caspase 3 | 0.015 | ||
| Agtr2 | angiotensin II receptor, type 2 | 0.015 | ||
| Obp3 | alpha-2u globulin PGCL4 | 0.015 | ||
| Sfrp4 | secreted frizzled-related protein 4 | 0.015 | ||
| Megf6 | multiple EGF-like-domains 6 | 0.015 | ||
| Vegfa | vascular endothelial growth factor A | 0.015 | ||
| Fstl1 | follistatin-like 1 | 0.015 | ||
| Pdcl | phosducin-like | 0.014 | ||
| Ldb1 | LIM domain binding 1 | 0.014 | ||
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.014 | ||
| Itpkb | inositol 1,4,5-trisphosphate 3-kinase B | 0.014 | ||
| Ptgis | prostaglandin I2 (prostacyclin) synthase | 0.014 | ||
| Cyp21a1 | cytochrome P450, family 21, subfamily a, polypeptide 1 | 0.014 | ||
| Fxyd5 | FXYD domain-containing ion transport regulator 5 | 0.014 | ||
| Gfap | glial fibrillary acidic protein | 0.013 | ||
| Prl8a2 | prolactin family 8, subfamily a, member 2 | 0.013 | ||
| Col9a2 | collagen, type IX, alpha 2 | 0.013 | Rat | |
| Prelp | proline/arginine-rich end leucine-rich repeat protein | 0.013 | ||
| Gata6 | GATA binding protein 6 | 0.013 | ||
| Sparc | secreted protein, acidic, cysteine-rich (osteonectin) | 0.013 | Zebrafish | |
| Ogn | osteoglycin | 0.013 | ||
| Gdnf | glial cell derived neurotrophic factor | 0.013 | ||
| Cdkn2b | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 0.013 | ||
| Ucp2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.013 | ||
| Rxra | retinoid X receptor alpha | 0.013 | ||
| Manea | mannosidase, endo-alpha | 0.013 | ||
| Cacna1g | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.012 | ||
| Rnase1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.012 | ||
| Vom1r101 | vomeronasal 1 receptor 101 | 0.012 | ||
| Pdpn | podoplanin | 0.012 | ||
| Usf2 | upstream transcription factor 2, c-fos interacting | 0.012 | ||
| Amh | anti-Mullerian hormone | 0.012 | ||
| Ntn1 | netrin 1 | 0.012 | ||
| Serpinh1 | serine (or cysteine) peptidase inhibitor, clade H, member 1 | 0.012 | Mouse | |
| Ncan | neurocan | 0.012 | Rat | |
| Ier3 | immediate early response 3 | 0.012 | ||
| Nr2f6 | nuclear receptor subfamily 2, group F, member 6 | 0.012 | ||
| Fgf22 | fibroblast growth factor 22 | 0.012 | ||
| Nek9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.012 | ||
| Slc4a4 | solute carrier family 4, sodium bicarbonate cotransporter, member 4 | 0.012 | ||
| Socs3 | suppressor of cytokine signaling 3 | 0.012 | ||
| Dlx5 | distal-less homeobox 5 | 0.012 | Zebrafish | |
| Klk1b3 | kallikrein 1-related peptidase b3 | 0.012 | ||
| Rnf138 | ring finger protein 138 | 0.012 | ||
| Eno1 | enolase 1, (alpha) | 0.012 | ||
| Enpp1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.012 | ||
| Rest | RE1-silencing transcription factor | 0.012 | ||
| Rhox5 | reproductive homeobox 5 | 0.012 | ||
| Fgd4 | FYVE, RhoGEF and PH domain containing 4 | 0.012 | ||
| Col5a3 | collagen, type V, alpha 3 | 0.012 | Rat | |
| Bmp7 | bone morphogenetic protein 7 | 0.011 | ||
| Col11a2 | collagen, type XI, alpha 2 | 0.011 | Human Rat | |
| LOC304558 | similar to TPR repeat-containing protein KIAA1043 | 0.011 | ||
| Cytl1 | cytokine like 1 | 0.011 | ||
| Tcf3 | transcription factor 3 | 0.011 | ||
| Mmp2 | matrix metallopeptidase 2 | 0.011 | ||
| RGD1561517 | similar to chromosome 20 open reading frame 144 | 0.011 | ||
| F13a1 | coagulation factor XIII, A1 polypeptide | 0.011 | ||
| Slc20a2 | solute carrier family 20 (phosphate transporter), member 2 | 0.011 | ||
| Abcc1 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 | 0.011 | ||
| Ostc | oligosaccharyltransferase complex subunit | 0.011 | ||
| Vdr | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.011 | ||
| Sox4 | SRY (sex determining region Y)-box 4 | 0.011 | ||
| Crygc | crystallin, gamma C | 0.011 | ||
| Stmn4 | stathmin-like 4 | 0.011 | ||
| Vasp | vasodilator-stimulated phosphoprotein | 0.011 | ||
| Pmepa1 | prostate transmembrane protein, androgen induced 1 | 0.011 | ||
| Cdk11b | cyclin-dependent kinase 11B | 0.011 | ||
| Casp2 | caspase 2 | 0.011 | ||
| Maf | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 0.011 | Mouse | |
| Acta2 | smooth muscle alpha-actin | 0.011 | ||
| Abcc6 | ATP-binding cassette, subfamily C (CFTR/MRP), member 6 | 0.011 | ||
| Ltbp3 | latent transforming growth factor beta binding protein 3 | 0.011 | ||
| Sh2b1 | SH2B adaptor protein 1 | 0.011 | ||
| Acan | aggrecan | 0.011 | ||
| Pate4 | prostate and testis expressed 4 | 0.011 | ||
| Sdc4 | syndecan 4 | 0.011 | ||
| Jak2 | Janus kinase 2 | 0.011 | ||
| Ril | reversion induced LIM gene | 0.011 | ||
| Lphn2 | latrophilin 2 | 0.011 | ||
| Capn6 | calpain 6 | 0.011 | ||
| Htr2c | 5-hydroxytryptamine (serotonin) receptor 2C | 0.011 | ||
| Smad7 | SMAD family member 7 | 0.011 | ||
| Mobp | myelin-associated oligodendrocyte basic protein | 0.011 | ||
| Dlc1 | deleted in liver cancer 1 | 0.011 | ||
| Nkd1 | naked cuticle homolog 1 (Drosophila) | 0.011 | ||
| Cyb5r3 | cytochrome b5 reductase 3 | 0.011 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.011 | ||
| Aldh4a1 | aldehyde dehydrogenase 4 family, member A1 | 0.011 | ||
| Npr3 | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 0.011 | ||
| Epn1 | Epsin 1 | 0.011 | ||
| Tbl1xr1 | transducin (beta)-like 1 X-linked receptor 1 | 0.010 | ||
| Rcor2 | REST corepressor 2 | 0.010 | ||
| Pomc | proopiomelanocortin | 0.010 | ||
| Copb2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.010 | ||
| Rab27a | RAB27A, member RAS oncogene family | 0.010 | ||
| Tusc5 | tumor suppressor candidate 5 | 0.010 | ||
| Lamb2 | laminin, beta 2 | 0.010 | ||
| Rod1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.010 | ||
| Mgat1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 0.010 | ||
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.010 |