IMP: Integrative Multi-species Prediction

Rattus norvegicus

28 genes annotated in rat

acyl coa metabolic process

The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "acyl coa metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "acyl coa metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Fasn	fatty acid synthase	0.997
Acaca	acetyl-coenzyme A carboxylase alpha	0.875
Hadhb	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	0.769
Pdha1	pyruvate dehydrogenase (lipoamide) alpha 1	0.702
Ech1	enoyl coenzyme A hydratase 1, peroxisomal	0.587
Acot2	acyl-CoA thioesterase 2	0.569
Acadm	acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	0.536
Fdft1	farnesyl diphosphate farnesyl transferase 1	0.531
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.502
Eci2	enoyl-Coenzyme A delta isomerase 2	0.492
Acat1	acetyl-coenzyme A acetyltransferase 1	0.471
Dld	dihydrolipoamide dehydrogenase	0.420
Acly	ATP citrate lyase	0.403
Mccc2	methylcrotonoyl-Coenzyme A carboxylase 2 (beta)	0.336
Uqcrc2	ubiquinol cytochrome c reductase core protein 2	0.300
Ndufs1	NADH dehydrogenase (ubiquinone) Fe-S protein 1	0.261
Acadvl	acyl-Coenzyme A dehydrogenase, very long chain	0.257
Dlat	dihydrolipoamide S-acetyltransferase	0.251
Etfb	electron-transfer-flavoprotein, beta polypeptide	0.220
Acat3	acetyl-Coenzyme A acetyltransferase 3	0.192
Tufm	Tu translation elongation factor, mitochondrial	0.189
Decr1	2,4-dienoyl CoA reductase 1, mitochondrial	0.184
Srebf1	sterol regulatory element binding transcription factor 1	0.177
Aldh6a1	aldehyde dehydrogenase 6 family, member A1	0.171
Idh3B	isocitrate dehydrogenase 3 (NAD+) beta	0.156
Pcyt2	phosphate cytidylyltransferase 2, ethanolamine	0.133
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.130
Etfdh	electron-transferring-flavoprotein dehydrogenase	0.125
Acot1	acyl-CoA thioesterase 1	0.122	Human Rat
Ivd	isovaleryl coenzyme A dehydrogenase	0.120
Slco1b3	solute carrier organic anion transporter family, member 1b3	0.119
Akap1	A kinase (PRKA) anchor protein 1	0.115
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.109
Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	0.106
Acadl	acyl-Coenzyme A dehydrogenase, long-chain	0.104
Me1	malic enzyme 1, NADP(+)-dependent, cytosolic	0.103
Acads	acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain	0.103
Tkt	transketolase	0.099
Scd1	stearoyl-Coenzyme A desaturase 1	0.099
Hadha	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	0.097
Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	0.095
Pgk1	phosphoglycerate kinase 1	0.088
Dhcr7	7-dehydrocholesterol reductase	0.084
Aldh9a1	aldehyde dehydrogenase 9 family, member A1	0.082
Bckdha	branched chain ketoacid dehydrogenase E1, alpha polypeptide	0.081
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.081
Hibadh	3-hydroxyisobutyrate dehydrogenase	0.081
Nfib	nuclear factor I/B	0.077
Tst	thiosulfate sulfurtransferase	0.069
Pex19	peroxisomal biogenesis factor 19	0.068
Isoc1	isochorismatase domain containing 1	0.066
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.061
Etfa	electron-transfer-flavoprotein, alpha polypeptide	0.060
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.060
Pfkm	phosphofructokinase, muscle	0.058
Eci1	enoyl-Coenzyme A delta isomerase 1	0.058
Dnaja3	DnaJ (Hsp40) homolog, subfamily A, member 3	0.057
Pdhb	pyruvate dehydrogenase (lipoamide) beta	0.055
Hadh	hydroxyacyl-Coenzyme A dehydrogenase	0.054
Adk	adenosine kinase	0.053
Lss	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	0.051
Fh1	fumarate hydratase 1	0.048
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.046
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)	0.038
Dao	D-amino-acid oxidase	0.036
Isca1	iron-sulfur cluster assembly 1 homolog (S. cerevisiae)	0.036
Slc25a20	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20	0.036
Hspa9	heat shock protein 9	0.036
Aldh7a1	aldehyde dehydrogenase 7 family, member A1	0.036
Zfyve21	zinc finger, FYVE domain containing 21	0.036
Mecr	mitochondrial trans-2-enoyl-CoA reductase	0.035
Hnf4a	hepatocyte nuclear factor 4, alpha	0.035
Glud1	glutamate dehydrogenase 1	0.035
Tmem14c	transmembrane protein 14C	0.034
Ddt	D-dopachrome tautomerase	0.034
Fgfr4	fibroblast growth factor receptor 4	0.032
Acaa2	acetyl-Coenzyme A acyltransferase 2	0.031
Car14	carbonic anhydrase 14	0.030
Gbe1	glucan (1,4-alpha-), branching enzyme 1	0.030
Zadh2	zinc binding alcohol dehydrogenase, domain containing 2	0.029
Tom1	target of myb1 homolog (chicken)	0.029
RGD1565095	similar to hypothetical protein MGC52110	0.028
Thrb	thyroid hormone receptor beta	0.028
Ndufs2	NADH dehydrogenase (ubiquinone) Fe-S protein 2	0.027
Acacb	acetyl-Coenzyme A carboxylase beta	0.027
Aifm1	apoptosis-inducing factor, mitochondrion-associated 1	0.026
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.026
Mug1	murinoglobulin 1	0.026
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.025
Slc25a42	solute carrier family 25, member 42	0.025
Nfs1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)	0.025
Ap1ar	adaptor-related protein complex 1 associated regulatory protein	0.025
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.024
Mvk	mevalonate kinase	0.024
Pink1	PTEN induced putative kinase 1	0.024
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.024
Chrna3	cholinergic receptor, nicotinic, alpha 3	0.023
Dbi	diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)	0.022
Dmgdh	dimethylglycine dehydrogenase	0.022
Ppp1r3c	protein phosphatase 1, regulatory (inhibitor) subunit 3C	0.022
Irx1	iroquois homeobox 1	0.021
Brp44l	brain protein 44-like	0.021
Suclg1	succinate-CoA ligase, alpha subunit	0.021
Ppp1r3b	protein phosphatase 1, regulatory (inhibitor) subunit 3B	0.021
Ddc	dopa decarboxylase (aromatic L-amino acid decarboxylase)	0.021
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.021
Slc25a10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	0.021
Cyth1	cytohesin 1	0.021
Ppcs	phosphopantothenoylcysteine synthetase	0.020
Bckdhb	branched chain keto acid dehydrogenase E1, beta polypeptide	0.020
Pah	phenylalanine hydroxylase	0.020
Gnmt	glycine N-methyltransferase	0.020
Nit2	nitrilase family, member 2	0.020
Dlst	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	0.020
Dio1	deiodinase, iodothyronine, type I	0.019
Stx2	syntaxin 2	0.019
Mlycd	malonyl-CoA decarboxylase	0.019
Cyp51	cytochrome P450, family 51	0.019
Fam162a	family with sequence similarity 162, member A	0.019
Serpina7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7	0.018
Slc37a4	solute carrier family 37 (glucose-6-phosphate transporter), member 4	0.018
Mtus1	mitochondrial tumor suppressor 1	0.018
Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.018
Pdhx	pyruvate dehydrogenase complex, component X	0.018
Keg1	kidney expressed gene 1	0.018
Vdac1	voltage-dependent anion channel 1	0.018
Grsf1	G-rich RNA sequence binding factor 1	0.018
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.018
Aqp7	aquaporin 7	0.018
Acsl1	acyl-CoA synthetase long-chain family member 1	0.017
Serpina11	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11	0.017
Gfm1	G elongation factor, mitochondrial 1	0.017
Atp9b	ATPase, class II, type 9B	0.017
Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	0.017
Dynlt3	dynein light chain Tctex-type 3	0.017
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.017
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.017
Acot12	acyl-CoA thioesterase 12	0.017
Vdac2	voltage-dependent anion channel 2	0.016
Txnrd2	thioredoxin reductase 2	0.016
Pc	pyruvate carboxylase	0.016
Akt2	v-akt murine thymoma viral oncogene homolog 2	0.016
Sult1b1	sulfotransferase family, cytosolic, 1B, member 1	0.016
Vegfa	vascular endothelial growth factor A	0.016
Tfrc	transferrin receptor	0.016
Gulo	gulonolactone (L-) oxidase	0.016
Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	0.016
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.016
UST4r	integral membrane transport protein UST4r	0.016
Cad	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.016
RGD1565591	similar to Ski protein	0.016
Sardh	sarcosine dehydrogenase	0.016
Baat	bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.015	Human Rat
Pmpca	peptidase (mitochondrial processing) alpha	0.015
Aacs	acetoacetyl-CoA synthetase	0.015
Csnk1g2	casein kinase 1, gamma 2	0.015
Gcgr	glucagon receptor	0.015
Sord	sorbitol dehydrogenase	0.015
Psbpc1	prostatic steroid binding protein C1	0.014
Ptp4a1	protein tyrosine phosphatase type IVA, member 1	0.014
Pex1	peroxisomal biogenesis factor 1	0.014
Chp	calcium binding protein p22	0.014
Thrsp	thyroid hormone responsive	0.014
Haao	3-hydroxyanthranilate 3,4-dioxygenase	0.014
Pcca	propionyl-coenzyme A carboxylase, alpha polypeptide	0.014
Hpn	hepsin	0.014
Fbp1	fructose-1,6-bisphosphatase 1	0.014
Ephx2	epoxide hydrolase 2, cytoplasmic	0.014
Ldhd	lactate dehydrogenase D	0.014
Ghitm	growth hormone inducible transmembrane protein	0.014
Mst1	Macrophage stimulating 1 (hepatocyte growth factor-like)	0.013
Mipep	mitochondrial intermediate peptidase	0.013
Cd36	CD36 molecule (thrombospondin receptor)	0.013
Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	0.013
Neu2	sialidase 2 (cytosolic sialidase)	0.013
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.013	Rat
Nsdhl	NAD(P) dependent steroid dehydrogenase-like	0.013
Dpys	dihydropyrimidinase	0.013
Agxt2l2	alanine-glyoxylate aminotransferase 2-like 2	0.013
Mosc2	MOCO sulphurase C-terminal domain containing 2	0.013
Dgat1	diacylglycerol O-acyltransferase homolog 1 (mouse)	0.013
Tspan18	tetraspanin 18	0.013
Rab17	RAB17, member RAS oncogene family	0.013
Akr1d1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.013
Slc25a15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	0.013
Impa2	inositol (myo)-1(or 4)-monophosphatase 2	0.013
Slbp	stem-loop binding protein	0.013
Ndfip1	Nedd4 family interacting protein 1	0.013
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.013
Hand2	heart and neural crest derivatives expressed 2	0.012
RGD1564865	similar to 20-alpha-hydroxysteroid dehydrogenase	0.012
Foxo1	forkhead box O1	0.012
LOC683801	similar to zinc finger protein 740	0.012
Sod2	superoxide dismutase 2, mitochondrial	0.012
Alad	aminolevulinate, delta-, dehydratase	0.012
Pitx2	paired-like homeodomain 2	0.012
Crybb1	crystallin, beta B1	0.012
Rest	RE1-silencing transcription factor	0.012
Neurl2	neuralized homolog 2 (Drosophila)	0.012
Ces2c	carboxylesterase 2C	0.012
Hist1h1b	histone cluster 1, H1b	0.012
Mtch2	mitochondrial carrier homolog 2 (C. elegans)	0.011
Cyb5b	cytochrome b5 type B (outer mitochondrial membrane)	0.011
Acsm3	acyl-CoA synthetase medium-chain family member 3	0.011	Rat
Clic4	chloride intracellular channel 4	0.011
Dpf3	D4, zinc and double PHD fingers, family 3	0.011
Slc20a2	solute carrier family 20 (phosphate transporter), member 2	0.011
Pgam2	phosphoglycerate mutase 2 (muscle)	0.011
Nudt6	nudix (nucleoside diphosphate linked moiety X)-type motif 6	0.011
Pex5	peroxisomal biogenesis factor 5	0.011
Fgf13	fibroblast growth factor 13	0.011
Arfgap2	ADP-ribosylation factor GTPase activating protein 2	0.011
Pzp	pregnancy-zone protein	0.011
Tmem82	transmembrane protein 82	0.010
Auh	AU RNA binding protein/enoyl-coenzyme A hydratase	0.010
Fabp12	fatty acid binding protein 12	0.010
Bbox1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	0.010
Vegfb	vascular endothelial growth factor B	0.010
Map3k7ip1	mitogen-activated protein kinase kinase kinase 7 interacting protein 1	0.010
Cldn1	claudin 1	0.010
Hoxc4	homeo box C4	0.010
Macrod1	MACRO domain containing 1	0.010
Srrm1	serine/arginine repetitive matrix 1	0.010
Nfia	nuclear factor I/A	0.010
Nfix	nuclear factor I/X (CCAAT-binding transcription factor)	0.010
Lrrc39	leucine rich repeat containing 39	0.010