IMP
Process View
fatty acid beta oxidation
A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "fatty acid beta oxidation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Decr1 | 2,4-dienoyl CoA reductase 1, mitochondrial | 1.000 | Human | |
| Acadl | acyl-Coenzyme A dehydrogenase, long-chain | 1.000 | ||
| Acaa2 | acetyl-Coenzyme A acyltransferase 2 | 1.000 | ||
| Ech1 | enoyl coenzyme A hydratase 1, peroxisomal | 0.999 | ||
| Cpt2 | carnitine palmitoyltransferase 2 | 0.999 | ||
| Acadvl | acyl-Coenzyme A dehydrogenase, very long chain | 0.999 | ||
| Etfdh | electron-transferring-flavoprotein dehydrogenase | 0.997 | ||
| Acadm | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 0.995 | ||
| Slc25a20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 | 0.976 | ||
| Hsd17b4 | hydroxysteroid (17-beta) dehydrogenase 4 | 0.974 | Human | |
| Eci2 | enoyl-Coenzyme A delta isomerase 2 | 0.955 | ||
| Acot2 | acyl-CoA thioesterase 2 | 0.773 | ||
| Acox1 | acyl-Coenzyme A oxidase 1, palmitoyl | 0.756 | ||
| Hadhb | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 0.727 | ||
| Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 | 0.660 | ||
| Crat | carnitine acetyltransferase | 0.454 | Rat | |
| Gsta4 | glutathione S-transferase alpha 4 | 0.370 | ||
| Lonp2 | lon peptidase 2, peroxisomal | 0.355 | ||
| Eci1 | enoyl-Coenzyme A delta isomerase 1 | 0.311 | Mouse | |
| Acads | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 0.309 | ||
| Hmgcs2 | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) | 0.294 | ||
| Etfa | electron-transfer-flavoprotein, alpha polypeptide | 0.285 | ||
| RGD1308772 | similar to KIAA0564 protein | 0.274 | ||
| Etfb | electron-transfer-flavoprotein, beta polypeptide | 0.263 | ||
| Retsat | retinol saturase (all trans retinol 13,14 reductase) | 0.249 | ||
| Hsd17b10 | hydroxysteroid (17-beta) dehydrogenase 10 | 0.195 | ||
| Ephx2 | epoxide hydrolase 2, cytoplasmic | 0.192 | ||
| Mccc2 | methylcrotonoyl-Coenzyme A carboxylase 2 (beta) | 0.181 | ||
| Phyh | phytanoyl-CoA 2-hydroxylase | 0.164 | ||
| Hmgcl | 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase | 0.160 | ||
| Hadha | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 0.129 | ||
| Suclg2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.124 | ||
| Aco1 | aconitase 1, soluble | 0.119 | ||
| Acat1 | acetyl-coenzyme A acetyltransferase 1 | 0.116 | ||
| Oplah | 5-oxoprolinase (ATP-hydrolysing) | 0.100 | ||
| Eef2 | eukaryotic translation elongation factor 2 | 0.095 | ||
| Slc25a42 | solute carrier family 25, member 42 | 0.095 | ||
| Gcdh | glutaryl-Coenzyme A dehydrogenase | 0.080 | ||
| Cd36 | CD36 molecule (thrombospondin receptor) | 0.079 | ||
| Dhrs4 | dehydrogenase/reductase (SDR family) member 4 | 0.069 | ||
| LOC684270 | similar to isochorismatase domain containing 2 | 0.064 | ||
| Impa2 | inositol (myo)-1(or 4)-monophosphatase 2 | 0.062 | ||
| Acad10 | acyl-Coenzyme A dehydrogenase family, member 10 | 0.058 | ||
| Acaa1a | acetyl-Coenzyme A acyltransferase 1A | 0.058 | ||
| Pxmp2 | peroxisomal membrane protein 2 | 0.056 | ||
| Ptgr1 | prostaglandin reductase 1 | 0.055 | ||
| Itga7 | integrin, alpha 7 | 0.054 | ||
| Ocln | occludin | 0.054 | ||
| Aqp7 | aquaporin 7 | 0.054 | ||
| Ano10 | anoctamin 10 | 0.051 | ||
| Lipa | lipase A, lysosomal acid, cholesterol esterase | 0.048 | ||
| Ghr | growth hormone receptor | 0.048 | ||
| Ldhd | lactate dehydrogenase D | 0.047 | ||
| Nudt7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 | 0.045 | ||
| Ldhb | lactate dehydrogenase B | 0.043 | ||
| Art2 | ADP-ribosyltransferase 2 | 0.043 | ||
| Acsl1 | acyl-CoA synthetase long-chain family member 1 | 0.042 | Rat | |
| Ak3 | adenylate kinase 3 | 0.042 | ||
| Mosc2 | MOCO sulphurase C-terminal domain containing 2 | 0.041 | ||
| Cabc1 | chaperone, ABC1 activity of bc1 complex homolog (S. pombe) | 0.040 | ||
| Stxbp3 | syntaxin binding protein 3 | 0.039 | ||
| Gstk1 | glutathione S-transferase kappa 1 | 0.038 | ||
| Tcfe2a | transcription factor E2a | 0.035 | ||
| Gpam | glycerol-3-phosphate acyltransferase, mitochondrial | 0.035 | ||
| Mlycd | malonyl-CoA decarboxylase | 0.034 | ||
| Aldh9a1 | aldehyde dehydrogenase 9 family, member A1 | 0.032 | ||
| Hadh | hydroxyacyl-Coenzyme A dehydrogenase | 0.031 | ||
| Rab1b | RAB1B, member RAS oncogene family | 0.031 | ||
| Slc27a1 | solute carrier family 27 (fatty acid transporter), member 1 | 0.030 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.030 | ||
| Cmbl | carboxymethylenebutenolidase homolog (Pseudomonas) | 0.030 | ||
| Decr2 | 2,4-dienoyl CoA reductase 2, peroxisomal | 0.030 | ||
| Akr7a2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.027 | ||
| Gpt | glutamic-pyruvate transaminase (alanine aminotransferase) | 0.027 | ||
| Hsdl2 | hydroxysteroid dehydrogenase like 2 | 0.027 | ||
| Lipe | lipase, hormone sensitive | 0.026 | ||
| Cpt1a | carnitine palmitoyltransferase 1a, liver | 0.026 | ||
| Slc22a5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | 0.026 | ||
| RGD1311756 | similar to hypothetical protein FLJ20950 | 0.026 | ||
| Pccb | propionyl coenzyme A carboxylase, beta polypeptide | 0.025 | ||
| Smpdl3a | sphingomyelin phosphodiesterase, acid-like 3A | 0.025 | ||
| Nit2 | nitrilase family, member 2 | 0.024 | ||
| Zadh2 | zinc binding alcohol dehydrogenase, domain containing 2 | 0.023 | ||
| Nefm | neurofilament, medium polypeptide | 0.023 | ||
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.023 | ||
| Usf2 | upstream transcription factor 2, c-fos interacting | 0.022 | ||
| RGD1561459 | similar to RIKEN cDNA 1810020D17 | 0.022 | ||
| RGD1307222 | similar to mKIAA0664 protein | 0.022 | ||
| Acot12 | acyl-CoA thioesterase 12 | 0.022 | ||
| Akr1c14 | aldo-keto reductase family 1, member C14 | 0.022 | ||
| Hacl1 | 2-hydroxyacyl-CoA lyase 1 | 0.022 | ||
| Cyp4f6 | cytochrome P450, family 4, subfamily f, polypeptide 6 | 0.021 | ||
| Pdk2 | pyruvate dehydrogenase kinase, isozyme 2 | 0.021 | ||
| Scp2 | sterol carrier protein 2 | 0.021 | ||
| Abcd3 | ATP-binding cassette, subfamily D (ALD), member 3 | 0.021 | Human | |
| Mipep | mitochondrial intermediate peptidase | 0.021 | ||
| Fabp1 | fatty acid binding protein 1, liver | 0.021 | ||
| Bckdha | branched chain ketoacid dehydrogenase E1, alpha polypeptide | 0.021 | ||
| Adcy6 | adenylate cyclase 6 | 0.020 | ||
| Ehhadh | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 0.020 | Mouse | |
| Cpped1 | calcineurin-like phosphoesterase domain containing 1 | 0.020 | ||
| Aldh2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.020 | ||
| Nnt | nicotinamide nucleotide transhydrogenase | 0.020 | ||
| Hsd17b11 | hydroxysteroid (17-beta) dehydrogenase 11 | 0.019 | ||
| Sult1b1 | sulfotransferase family, cytosolic, 1B, member 1 | 0.019 | ||
| Fabp3 | fatty acid binding protein 3, muscle and heart | 0.018 | ||
| Angptl4 | angiopoietin-like 4 | 0.018 | ||
| Idh1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.018 | Yeast | |
| Acad11 | acyl-Coenzyme A dehydrogenase family, member 11 | 0.018 | ||
| Pex19 | peroxisomal biogenesis factor 19 | 0.018 | ||
| Bckdhb | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.017 | ||
| Mgst1 | microsomal glutathione S-transferase 1 | 0.017 | ||
| Hnf1a | HNF1 homeobox A | 0.017 | ||
| As3mt | arsenic (+3 oxidation state) methyltransferase | 0.017 | ||
| Dpp4 | dipeptidylpeptidase 4 | 0.016 | ||
| Pink1 | PTEN induced putative kinase 1 | 0.016 | ||
| Npepl1 | aminopeptidase-like 1 | 0.016 | ||
| Myf6 | myogenic factor 6 | 0.016 | ||
| Mgll | monoglyceride lipase | 0.015 | ||
| RGD1308874 | similar to RIKEN cDNA 2310001A20 | 0.015 | ||
| Pex11a | peroxisomal biogenesis factor 11 alpha | 0.015 | ||
| Nudt6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | 0.015 | ||
| Ppp2r5a | protein phosphatase 2, regulatory subunit B', alpha isoform | 0.015 | ||
| Xcl1 | chemokine (C motif) ligand 1 | 0.015 | ||
| Cyp4a3 | cytochrome P450, family 4, subfamily a, polypeptide 3 | 0.015 | ||
| Atp1b1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.015 | ||
| Tmem150a | transmembrane protein 150A | 0.015 | ||
| Adh1 | alcohol dehydrogenase 1 (class I) | 0.015 | ||
| Slco1b3 | solute carrier organic anion transporter family, member 1b3 | 0.014 | ||
| Echs1 | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 0.014 | ||
| Plin5 | perilipin 5 | 0.014 | ||
| Scg3 | secretogranin III | 0.014 | ||
| Gsta5 | glutathione S-transferase Yc2 subunit | 0.014 | ||
| Thnsl2 | threonine synthase-like 2 (S. cerevisiae) | 0.014 | ||
| RGD1306000 | similar to CG8043-PA | 0.013 | ||
| Mpst | mercaptopyruvate sulfurtransferase | 0.013 | ||
| Gucy2g | guanylate cyclase 2G | 0.013 | ||
| Ttpa | tocopherol (alpha) transfer protein | 0.013 | ||
| Unc50 | unc-50 homolog (C. elegans) | 0.013 | ||
| March8 | membrane-associated ring finger (C3HC4) 8 | 0.013 | ||
| Fabp2 | fatty acid binding protein 2, intestinal | 0.013 | ||
| Flt1 | FMS-related tyrosine kinase 1 | 0.013 | ||
| Naalad2 | N-acetylated alpha-linked acidic dipeptidase 2 | 0.013 | ||
| LOC690000 | similar to CG3740-PA | 0.012 | ||
| Acot7 | acyl-CoA thioesterase 7 | 0.012 | ||
| Ugt8 | UDP glycosyltransferase 8 | 0.012 | ||
| RGD1564878 | similar to natural killer cell protease 7 | 0.012 | ||
| Txnrd2 | thioredoxin reductase 2 | 0.012 | ||
| Pik3r1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.012 | ||
| Aldh5a1 | aldehyde dehydrogenase 5 family, member A1 | 0.012 | ||
| Hsd17b12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.012 | ||
| LOC100364835 | histone cluster 1, H2bd-like | 0.012 | ||
| Runx3 | runt-related transcription factor 3 | 0.012 | ||
| Fsd2 | fibronectin type III and SPRY domain containing 2 | 0.012 | ||
| Vegfb | vascular endothelial growth factor B | 0.011 | ||
| Acp2 | acid phosphatase 2, lysosomal | 0.011 | ||
| Slc25a10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 0.011 | ||
| Syngr1 | synaptogyrin 1 | 0.011 | ||
| RGD1563224 | similar to 4930438D12Rik protein | 0.011 | ||
| Slc25a13 | solute carrier family 25, member 13 (citrin) | 0.011 | ||
| Fam96a | family with sequence similarity 96, member A | 0.011 | ||
| Plcg2 | phospholipase C, gamma 2 | 0.011 | ||
| Rab5b | RAB5B, member RAS oncogene family | 0.011 | ||
| Cat | catalase | 0.011 | ||
| Tmem143 | transmembrane protein 143 | 0.011 | ||
| RGD1311612 | similar to hypothetical protein FLJ12118 | 0.011 | ||
| Pdk1 | pyruvate dehydrogenase kinase, isozyme 1 | 0.011 | ||
| Inpp4b | inositol polyphosphate-4-phosphatase, type II | 0.011 | ||
| RGD1311273 | similar to RIKEN cDNA 9530058B02 | 0.011 | ||
| Amy2 | amylase 2, pancreatic | 0.011 | ||
| Isoc1 | isochorismatase domain containing 1 | 0.011 | ||
| Mcpt1 | mast cell protease 1 | 0.011 | ||
| Hibadh | 3-hydroxyisobutyrate dehydrogenase | 0.011 | ||
| Lpcat3 | lysophosphatidylcholine acyltransferase 3 | 0.011 | ||
| Fam21c | family with sequence similarity 21, member C | 0.011 | ||
| Dgat1 | diacylglycerol O-acyltransferase homolog 1 (mouse) | 0.011 | ||
| Slc22a3 | solute carrier family 22 (extraneuronal monoamine transporter), member 3 | 0.011 | ||
| Cyp17a1 | cytochrome P450, family 17, subfamily a, polypeptide 1 | 0.011 | ||
| Odf4 | outer dense fiber of sperm tails 4 | 0.011 | ||
| Cryab | crystallin, alpha B | 0.011 | ||
| Ctdsp1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | 0.011 | ||
| Wsb2 | WD repeat and SOCS box-containing 2 | 0.011 | ||
| Dcaf11 | DDB1 and CUL4 associated factor 11 | 0.011 | ||
| Sord | sorbitol dehydrogenase | 0.010 | ||
| Pparg | peroxisome proliferator-activated receptor gamma | 0.010 | ||
| Mro | maestro | 0.010 | ||
| Abhd6 | abhydrolase domain containing 6 | 0.010 | ||
| Ndufa10l1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 1 | 0.010 | ||
| Ghdc | GH3 domain containing | 0.010 | ||
| Lenep | lens epithelial protein | 0.010 | ||
| Pdss2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | 0.010 |