IMP: Integrative Multi-species Prediction

Rattus norvegicus

2 genes annotated in rat

lymphoid progenitor cell differentiation

The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lymphoid progenitor cell differentiation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "lymphoid progenitor cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Unc5b	unc-5 homolog B (C. elegans)	0.405
Nos3	nitric oxide synthase 3, endothelial cell	0.371
Flt1	FMS-related tyrosine kinase 1	0.283	Rat
Ggt1	gamma-glutamyltransferase 1	0.265
C1qc	complement component 1, q subcomponent, C chain	0.249
Trhr2	thyrotropin releasing hormone receptor 2	0.222
Epas1	endothelial PAS domain protein 1	0.216
Fcn1	ficolin (collagen/fibrinogen domain containing) 1	0.211
Acacb	acetyl-Coenzyme A carboxylase beta	0.202
Gata6	GATA binding protein 6	0.148
Hoxc4	homeo box C4	0.141
Sox17	SRY (sex determining region Y)-box 17	0.135
Wipf1	WAS/WASL interacting protein family, member 1	0.134
Il1r1	interleukin 1 receptor, type I	0.122
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.120	Rat
Vwf	von Willebrand factor	0.119
Add3	adducin 3 (gamma)	0.112
Cd4	Cd4 molecule	0.111
Rhov	ras homolog gene family, member V	0.095
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.094
Chrm1	cholinergic receptor, muscarinic 1	0.083
Klk1b3	kallikrein 1-related peptidase b3	0.073
Lphn3	latrophilin 3	0.072
Pip4k2b	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	0.070
Utrn	utrophin	0.070
Six3	SIX homeobox 3	0.069
Axl	Axl receptor tyrosine kinase	0.069
Bglap	bone gamma-carboxyglutamate (gla) protein	0.069
RT1-DOa	RT1 class II, locus DOa	0.069
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.066
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.066
Gna15	guanine nucleotide binding protein, alpha 15	0.063
LOC100360403	ATP-binding cassette, sub-family C, member 9-like	0.062
Fgfr2	fibroblast growth factor receptor 2	0.062
Jag2	jagged 2	0.060
Hpcal4	hippocalcin-like 4	0.058
Lhx1	LIM homeobox 1	0.055
Unc5a	unc-5 homolog A (C. elegans)	0.055
Flt4	fms-related tyrosine kinase 4	0.054	Rat
Ddr2	discoidin domain receptor tyrosine kinase 2	0.054
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.054
Lep	leptin	0.053
Twist2	twist homolog 2 (Drosophila)	0.053
Crybb3	crystallin, beta B3	0.053
Bmp6	bone morphogenetic protein 6	0.053
Pde4c	phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)	0.052
Nrg2	neuregulin 2	0.052
Mapk3	mitogen activated protein kinase 3	0.052
Megf6	multiple EGF-like-domains 6	0.051
RGD1564163	similar to RIKEN cDNA 1700025K23	0.051
Sost	sclerosteosis	0.049
Cmtm3	CKLF-like MARVEL transmembrane domain containing 3	0.048
Npr1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.048
Cntfr	ciliary neurotrophic factor receptor	0.047
Bcl2l1	Bcl2-like 1	0.047
Cyth3	cytohesin 3	0.047
Smo	smoothened homolog (Drosophila)	0.047
Pdzd2	PDZ domain containing 2	0.045
Itgam	integrin, alpha M	0.044
LOC679931	hypothetical protein LOC679931	0.040
Cyth1	cytohesin 1	0.040
Epn2	epsin 2	0.040
Sdc3	syndecan 3	0.040
Pdgfb	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.039
Tgfbr3	transforming growth factor, beta receptor III	0.039
Mpp3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	0.038
Notch4	Notch homolog 4 (Drosophila)	0.038
Galr3	galanin receptor 3	0.038
Gpr116	G protein-coupled receptor 116	0.038
Nxph3	neurexophilin 3	0.038
Pax8	paired box 8	0.037
Hfe	hemochromatosis	0.037
Cdh5	cadherin 5	0.036
Hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.035
RGD1565591	similar to Ski protein	0.035
Dmd	dystrophin	0.035
Colec12	collectin sub-family member 12	0.034
Tril	TLR4 interactor with leucine-rich repeats	0.034
Amh	anti-Mullerian hormone	0.033
Acot2	acyl-CoA thioesterase 2	0.033
Coq10a	coenzyme Q10 homolog A (S. cerevisiae)	0.033
Lad1	ladinin 1	0.033
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.032
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.031
Bcl2	B-cell CLL/lymphoma 2	0.031	Mouse
Dchs1	dachsous 1 (Drosophila)	0.030
Adra2b	adrenergic, alpha-2B-, receptor	0.030
Gulo	gulonolactone (L-) oxidase	0.030
Cfh	complement factor H	0.030
Timp3	TIMP metallopeptidase inhibitor 3	0.029
Prss22	protease, serine, 22	0.029
Spon1	spondin 1, extracellular matrix protein	0.029
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.029
Matk	megakaryocyte-associated tyrosine kinase	0.029
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.028
Cryge	crystallin, gamma E	0.028
Pld4	phospholipase D family, member 4	0.028
Bmp4	bone morphogenetic protein 4	0.028	Human
Fkbp9	FK506 binding protein 9	0.028
Lama2	laminin, alpha 2	0.028
RT1-M4	RT1 class Ib, locus M4	0.027
Cmklr1	chemokine-like receptor 1	0.027
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.027
Gja4	gap junction protein, alpha 4	0.026
Olr837	olfactory receptor 837	0.026
Tyrobp	Tyro protein tyrosine kinase binding protein	0.026
RT1-Ha	RT1 class II, locus Ha	0.025
Rin2	Ras and Rab interactor 2	0.025
Camk2n2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.025
Clec11a	C-type lectin domain family 11, member a	0.025
Otp	orthopedia homeobox	0.025
Otx1	orthodenticle homeobox 1	0.024
LOC100361571	keratin associated protein 1-3-like	0.024
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.024
Cebpe	CCAAT/enhancer binding protein (C/EBP), epsilon	0.024
Insrr	insulin receptor-related receptor	0.023
Nfia	nuclear factor I/A	0.023
Kcne1	potassium voltage-gated channel, Isk-related family, member 1	0.022
LOC259246	alpha-2u globulin PGCL1	0.022
Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.022
Lgals9	lectin, galactoside-binding, soluble, 9	0.022
Accn2	amiloride-sensitive cation channel 2, neuronal	0.022
Sh2b3	SH2B adaptor protein 3	0.022
Fgf17	fibroblast growth factor 17	0.022
Panx3	pannexin 3	0.022
Homer3	homer homolog 3 (Drosophila)	0.021
Ephb3	Eph receptor B3	0.021
Lrp1	low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)	0.021
Slit1	slit homolog 1 (Drosophila)	0.021
Gper	G protein-coupled estrogen receptor 1	0.021
Btbd17	BTB (POZ) domain containing 17	0.021
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.021
Podxl	podocalyxin-like	0.021
Zfp382	zinc finger protein 382	0.021
Kcnf1	potassium voltage-gated channel, subfamily F, member 1	0.020
Gata3	GATA binding protein 3	0.020	Mouse
Snrk	SNF related kinase	0.020
Heph	hephaestin	0.020
Emr1	EGF-like module containing, mucin-like, hormone receptor-like 1	0.020
Ggt5	gamma-glutamyltransferase 5	0.020
Lgals2	lectin, galactoside-binding, soluble, 2	0.020
Slc20a2	solute carrier family 20 (phosphate transporter), member 2	0.019
Stat6	signal transducer and activator of transcription 6	0.019
RGD1563106	similar to novel protein	0.019
Lamc1	laminin, gamma 1	0.019
Klk8	kallikrein related-peptidase 8	0.019
Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2	0.019
Nckap1l	NCK associated protein 1 like	0.019
Fgf22	fibroblast growth factor 22	0.019
Tgfbr2	transforming growth factor, beta receptor II	0.019
Crygf	crystallin, gamma F	0.018
Atp1a4	ATPase, Na+/K+ transporting, alpha 4 polypeptide	0.018
Sox10	SRY (sex determining region Y)-box 10	0.018
Ccr10	chemokine (C-C motif) receptor 10	0.018
LOC100360587	hypothetical protein LOC100360587	0.018
Sardh	sarcosine dehydrogenase	0.018
Efnb1	ephrin B1	0.018
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.018
Grpca	glutamine/glutamic acid-rich protein A	0.018
Il5	interleukin 5	0.018
Nacc1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	0.018
Hrh1	histamine receptor H 1	0.018
Tle2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	0.018
Stat4	signal transducer and activator of transcription 4	0.018
Eif2b4	eukaryotic translation initiation factor 2B, subunit 4 delta	0.018
Sod3	superoxide dismutase 3, extracellular	0.018
Acaca	acetyl-coenzyme A carboxylase alpha	0.018
LOC100363145	stabilin 1	0.017
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.017
Clec3a	C-type lectin domain family 3, member a	0.017
Npw	neuropeptide W	0.017
Il11	interleukin 11	0.017
Kit	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.017	Mouse Rat
Fcho1	FCH domain only 1	0.017
Clec4a3	C-type lectin domain family 4, member a3	0.016
Slit3	slit homolog 3 (Drosophila)	0.016
Tek	TEK tyrosine kinase, endothelial	0.016
Txnrd2	thioredoxin reductase 2	0.016
Sbk1	SH3-binding domain kinase 1	0.016
Dlc1	deleted in liver cancer 1	0.016
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.016
Lipe	lipase, hormone sensitive	0.016
Prm2	protamine 2	0.016
Enpep	glutamyl aminopeptidase	0.016
Angpt2	angiopoietin 2	0.015
Cyp2b15	cytochrome P450, family 2, subfamily b, polypeptide 15	0.015
Kcna6	potassium voltage gated channel, shaker related subfamily, member 6	0.015
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.015
Zap70	zeta-chain (TCR) associated protein kinase	0.015
Zcchc24	zinc finger, CCHC domain containing 24	0.015
Fam160b1	family with sequence similarity 160, member B1	0.015
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.015
Fbxo2	F-box protein 2	0.015
Notch1	Notch homolog 1, translocation-associated (Drosophila)	0.015	Mouse
Il8ra	interleukin 8 receptor, alpha	0.014
Igfbp5	insulin-like growth factor binding protein 5	0.014
Arrb1	arrestin, beta 1	0.014
Lpar1	lysophosphatidic acid receptor 1	0.014
Kdr	kinase insert domain receptor	0.014
Agrn	agrin	0.014
Inhbe	inhibin beta E	0.014
Dock6	dedicator of cytokinesis 6	0.014
Gpr182	G protein-coupled receptor 182	0.014
Abhd14b	abhydrolase domain containing 14b	0.014
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.014
Pear1	platelet endothelial aggregation receptor 1	0.014
Arnt	aryl hydrocarbon receptor nuclear translocator	0.014
Mthfr	methylenetetrahydrofolate reductase (NAD(P)H)	0.014
Enpp1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.014
Cabin1	calcineurin binding protein 1	0.014
Kcnk1	potassium channel, subfamily K, member 1	0.014
Skap1	src kinase associated phosphoprotein 1	0.014
Rapgef3	Rap guanine nucleotide exchange factor (GEF) 3	0.014
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.014
Prss8	protease, serine, 8	0.014
Rem2	RAS (RAD and GEM) like GTP binding 2	0.014
Klf13	Kruppel-like factor 13	0.013
Robo1	roundabout homolog 1 (Drosophila)	0.013
Mgat3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase	0.013
Cyp2f4	cytochrome P450, family 2, subfamily f, polypeptide 4	0.013
Adrb1	adrenergic, beta-1-, receptor	0.013
Ank2	ankyrin 2, neuronal	0.013
Rnpep	arginyl aminopeptidase (aminopeptidase B)	0.013
Fibin	fin bud initiation factor homolog (zebrafish)	0.013
Crybb1	crystallin, beta B1	0.013
Sbp	spermine binding protein	0.013
Hes5	hairy and enhancer of split 5 (Drosophila)	0.013
Epha8	Eph receptor A8	0.013
Erg	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.013
Hspb2	heat shock protein beta 2	0.013
Mapk4	mitogen-activated protein kinase 4	0.013
F13a1	coagulation factor XIII, A1 polypeptide	0.013
Grin2a	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.013
Tal1	T-cell acute lymphocytic leukemia 1	0.013
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.013
RGD1564195	similar to hypothetical protein	0.012
Cldn7	claudin 7	0.012
Gpr98	G protein-coupled receptor 98	0.012
Foxq1	forkhead box Q1	0.012
Suox	sulfite oxidase	0.012
Ebf1	early B-cell factor 1	0.012
Hbe2	hemoglobin, epsilon 2	0.012
Bat3	HLA-B-associated transcript 3	0.012
Rhobtb1	Rho-related BTB domain containing 1	0.012
Tns3	tensin 3	0.012
Zfp278	zinc finger protein 278	0.012
Ttn	titin	0.012
Xylt2	xylosyltransferase II	0.012
Tlr7	toll-like receptor 7	0.012
Shc2	SHC (Src homology 2 domain containing) transforming protein 2	0.012
Pde4a	phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)	0.012
Fut4	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)	0.012
Ptgds	prostaglandin D2 synthase (brain)	0.012
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.012
Atp2a3	ATPase, Ca++ transporting, ubiquitous	0.012
Fam101a	family with sequence similarity 101, member A	0.012
Hmgcl	3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase	0.012
Extl3	exostoses (multiple)-like 3	0.012
Ankrd2	ankyrin repeat domain 2 (stretch responsive muscle)	0.012
Nfib	nuclear factor I/B	0.011
Ehf	ets homologous factor	0.011
Atoh8	atonal homolog 8 (Drosophila)	0.011
Frzb	frizzled-related protein	0.011
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.011
Ltbp2	latent transforming growth factor beta binding protein 2	0.011
Gab1	GRB2-associated binding protein 1	0.011
Vstm2b	V-set and transmembrane domain containing 2B	0.011
Sec3l1	SEC3-like 1 (S. cerevisiae)	0.011
Gpr176	G protein-coupled receptor 176	0.011
Prkch	protein kinase C, eta	0.011
LOC100362331	rCG59612-like	0.011
Flt3	fms-related tyrosine kinase 3	0.011
Ccr6	chemokine (C-C motif) receptor 6	0.011
Gjc2	gap junction protein, gamma 2	0.011
Nlgn3	neuroligin 3	0.011
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.011
Shc3	SHC (Src homology 2 domain containing) transforming protein 3	0.011
Slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.011
Igsf10	immunoglobulin superfamily, member 10	0.011
Ctrc	chymotrypsin C (caldecrin)	0.011
Plxnd1	plexin D1	0.011
Fbxo32	F-box protein 32	0.011
Olfml2a	olfactomedin-like 2A	0.011
Hand1	heart and neural crest derivatives expressed 1	0.011
Gdf10	growth differentiation factor 10	0.011
Fam198b	family with sequence similarity 198, member B	0.011
Synm	synemin, intermediate filament protein	0.011
Pou6f1	POU class 6 homeobox 1	0.011
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.011
Pdzk1ip1	PDZK1 interacting protein 1	0.010
Scube1	signal peptide, CUB domain, EGF-like 1	0.010
Mpnd	MPN domain containing	0.010
Rya3	antimicrobial peptide RYA3	0.010
Zfyve26	zinc finger, FYVE domain containing 26	0.010
Zbtb48	zinc finger and BTB domain containing 48	0.010
Pdgfa	platelet-derived growth factor alpha polypeptide	0.010
Fat2	FAT tumor suppressor homolog 2 (Drosophila)	0.010
Megf10	multiple EGF-like domains 10	0.010
Kif27	kinesin family member 27	0.010
Col8a1	collagen, type VIII, alpha 1	0.010
Nudt14	nudix (nucleoside diphosphate linked moiety X)-type motif 14	0.010
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.010
Snx33	sorting nexin 33	0.010
Vps11	vacuolar protein sorting 11 homolog (S. cerevisiae)	0.010
RGD1562717	similar to ABI gene family, member 3 (NESH) binding protein	0.010
Irs3	insulin receptor substrate 3	0.010
Klf15	Kruppel-like factor 15	0.010
Fads1	fatty acid desaturase 1	0.010
Ltbp3	latent transforming growth factor beta binding protein 3	0.010
Cabp4	calcium binding protein 4	0.010