IMP
Process View
negative regulation of protein import into nucleus translocation
Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein import into nucleus translocation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Pcnxl3 | pecanex-like 3 (Drosophila) | 0.394 | ||
| Stat2 | signal transducer and activator of transcription 2 | 0.224 | ||
| Rara | retinoic acid receptor, alpha | 0.168 | ||
| Csnk1g2 | casein kinase 1, gamma 2 | 0.143 | ||
| Rxra | retinoid X receptor alpha | 0.117 | Rat | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.102 | ||
| Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.067 | Rat | |
| Slc25a10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 0.064 | ||
| Stat6 | signal transducer and activator of transcription 6 | 0.060 | ||
| Sardh | sarcosine dehydrogenase | 0.055 | ||
| Sptbn2 | spectrin, beta, non-erythrocytic 2 | 0.055 | ||
| Tle2 | transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) | 0.051 | ||
| Ppt2 | palmitoyl-protein thioesterase 2 | 0.050 | ||
| Fgfr4 | fibroblast growth factor receptor 4 | 0.048 | ||
| Pqcp | polyglutamine-containing protein | 0.046 | ||
| Espn | espin | 0.045 | ||
| Thra | thyroid hormone receptor alpha | 0.043 | ||
| Adra1b | adrenergic, alpha-1B-, receptor | 0.041 | ||
| St3gal3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | 0.040 | ||
| Med25 | mediator complex subunit 25 | 0.038 | ||
| Tpcn1 | two pore segment channel 1 | 0.038 | ||
| Ifi35 | interferon-induced protein 35 | 0.037 | ||
| Srebf1 | sterol regulatory element binding transcription factor 1 | 0.037 | ||
| Tcf3 | transcription factor 3 | 0.037 | ||
| Gulo | gulonolactone (L-) oxidase | 0.037 | ||
| LOC100365106 | rCG32755-like | 0.037 | ||
| Foxo1 | forkhead box O1 | 0.037 | ||
| Fance | Fanconi anemia, complementation group E | 0.035 | ||
| RGD1565591 | similar to Ski protein | 0.035 | ||
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.034 | ||
| Gse1 | genetic suppressor element 1 | 0.034 | ||
| Acvr2b | activin A receptor, type IIB | 0.034 | ||
| Zadh2 | zinc binding alcohol dehydrogenase, domain containing 2 | 0.032 | ||
| Sox13 | SRY (sex determining region Y)-box 13 | 0.031 | ||
| Cabin1 | calcineurin binding protein 1 | 0.031 | ||
| Ddc | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 0.029 | ||
| Lphn1 | latrophilin 1 | 0.028 | ||
| Lrrc68 | leucine rich repeat containing 68 | 0.028 | ||
| Masp1 | mannan-binding lectin serine peptidase 1 | 0.027 | ||
| Akt2 | v-akt murine thymoma viral oncogene homolog 2 | 0.027 | ||
| LOC100360205 | palladin | 0.027 | ||
| Gucy1a3 | guanylate cyclase 1, soluble, alpha 3 | 0.026 | ||
| Fn3k | fructosamine 3 kinase | 0.025 | ||
| Usf2 | upstream transcription factor 2, c-fos interacting | 0.025 | ||
| Slc25a23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 | 0.025 | ||
| Pde4a | phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) | 0.024 | ||
| Slc25a42 | solute carrier family 25, member 42 | 0.024 | ||
| RGD1306404 | similar to mKIAA1402 protein | 0.024 | ||
| Acacb | acetyl-Coenzyme A carboxylase beta | 0.023 | ||
| Acox3 | acyl-Coenzyme A oxidase 3, pristanoyl | 0.023 | ||
| Gna11 | guanine nucleotide binding protein, alpha 11 | 0.023 | ||
| Nfix | nuclear factor I/X (CCAAT-binding transcription factor) | 0.023 | ||
| Pex14 | peroxisomal biogenesis factor 14 | 0.023 | ||
| Hdac11 | histone deacetylase 11 | 0.022 | ||
| Galnt2 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) | 0.022 | ||
| Brd3 | bromodomain containing 3 | 0.022 | ||
| Hspb6 | heat shock protein, alpha-crystallin-related, B6 | 0.021 | ||
| Sp110 | SP110 nuclear body protein | 0.021 | ||
| Notch1 | Notch homolog 1, translocation-associated (Drosophila) | 0.021 | ||
| Txnrd2 | thioredoxin reductase 2 | 0.021 | ||
| Axin2 | axin 2 | 0.021 | ||
| Foxa3 | forkhead box A3 | 0.020 | ||
| Slc6a13 | solute carrier family 6 (neurotransmitter transporter, GABA), member 13 | 0.020 | ||
| Ldlr | low density lipoprotein receptor | 0.020 | ||
| Syt3 | synaptotagmin III | 0.020 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.020 | ||
| Zmiz2 | zinc finger, MIZ-type containing 2 | 0.020 | ||
| Map3k7ip1 | mitogen-activated protein kinase kinase kinase 7 interacting protein 1 | 0.020 | ||
| Apbb1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.020 | ||
| Kdr | kinase insert domain receptor | 0.020 | ||
| Tfeb | transcription factor EB | 0.020 | ||
| RGD1307218 | similar to RIKEN cDNA 2810432L12 | 0.019 | ||
| Ttc36 | tetratricopeptide repeat domain 36 | 0.019 | ||
| Cyp27a1 | cytochrome P450, family 27, subfamily a, polypeptide 1 | 0.018 | ||
| Gna12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.018 | ||
| Nrp1 | neuropilin 1 | 0.018 | ||
| Lrsam1 | leucine rich repeat and sterile alpha motif containing 1 | 0.018 | ||
| Cdc42bpb | CDC42 binding protein kinase beta (DMPK-like) | 0.018 | ||
| Efnb1 | ephrin B1 | 0.018 | ||
| Epn1 | Epsin 1 | 0.018 | ||
| Shank3 | SH3 and multiple ankyrin repeat domains 3 | 0.018 | ||
| Aif1l | allograft inflammatory factor 1-like | 0.018 | ||
| Crp | C-reactive protein, pentraxin-related | 0.018 | ||
| Zfp362 | zinc finger protein 362 | 0.017 | ||
| Nfia | nuclear factor I/A | 0.017 | ||
| Hpn | hepsin | 0.017 | ||
| Hand2 | heart and neural crest derivatives expressed 2 | 0.017 | ||
| Cldn3 | claudin 3 | 0.017 | ||
| Palm | paralemmin | 0.017 | ||
| Rgs12 | regulator of G-protein signaling 12 | 0.017 | ||
| Klhl36 | kelch-like 36 (Drosophila) | 0.017 | ||
| Znf692 | zinc finger protein 692 | 0.017 | ||
| Cxxc5 | CXXC finger 5 | 0.016 | ||
| Slco2b1 | solute carrier organic anion transporter family, member 2b1 | 0.016 | ||
| Slc9a1 | solute carrier family 9 (sodium/hydrogen exchanger), member 1 | 0.016 | ||
| Slc13a3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | 0.016 | ||
| Rxrb | retinoid X receptor beta | 0.016 | Rat | |
| Arap1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.016 | ||
| Asmt | acetylserotonin O-methyltransferase | 0.016 | ||
| Rbck1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.016 | ||
| Me3 | malic enzyme 3, NADP(+)-dependent, mitochondrial | 0.015 | ||
| Cgnl1 | cingulin-like 1 | 0.015 | ||
| Ccnd3 | cyclin D3 | 0.015 | ||
| Foxp1 | forkhead box P1 | 0.015 | ||
| Homer2 | homer homolog 2 (Drosophila) | 0.015 | ||
| Sort1 | sortilin 1 | 0.015 | ||
| Slc37a4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.015 | ||
| Hsf1 | heat shock transcription factor 1 | 0.015 | ||
| Nfib | nuclear factor I/B | 0.015 | ||
| Cyp4a3 | cytochrome P450, family 4, subfamily a, polypeptide 3 | 0.015 | ||
| Slc22a5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | 0.014 | ||
| Pip4k2b | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.014 | ||
| Nfic | nuclear factor I/C | 0.014 | ||
| Polr2a | polymerase (RNA) II (DNA directed) polypeptide A | 0.014 | ||
| Gnb3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 | 0.014 | ||
| Kcnb1 | potassium voltage gated channel, Shab-related subfamily, member 1 | 0.014 | ||
| Irf1 | interferon regulatory factor 1 | 0.014 | ||
| LOC684035 | similar to arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.014 | ||
| Naprt1 | nicotinate phosphoribosyltransferase domain containing 1 | 0.014 | ||
| Dnm1 | dynamin 1 | 0.014 | ||
| Dgkz | diacylglycerol kinase zeta | 0.014 | ||
| Gata6 | GATA binding protein 6 | 0.013 | ||
| Slc20a2 | solute carrier family 20 (phosphate transporter), member 2 | 0.013 | ||
| Ldhd | lactate dehydrogenase D | 0.013 | ||
| Fam113b | family with sequence similarity 113, member B | 0.013 | ||
| Adcy6 | adenylate cyclase 6 | 0.013 | ||
| Camk2g | calcium/calmodulin-dependent protein kinase II gamma | 0.013 | ||
| Plxnd1 | plexin D1 | 0.013 | ||
| Phf1 | PHD finger protein 1 | 0.013 | ||
| Gtpbp3 | GTP binding protein 3 | 0.013 | ||
| Gga1 | golgi associated, gamma adaptin ear containing, ARF binding protein 1 | 0.013 | ||
| Acads | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 0.013 | ||
| Zfp462 | zinc finger protein 462 | 0.012 | ||
| Naga | N-acetyl galactosaminidase, alpha | 0.012 | ||
| Tcfe2a | transcription factor E2a | 0.012 | ||
| Cyp4f4 | cytochrome P450, family 4, subfamily f, polypeptide 4 | 0.012 | ||
| Eef2k | eukaryotic elongation factor-2 kinase | 0.012 | ||
| Dpyd | dihydropyrimidine dehydrogenase | 0.012 | ||
| Usp19 | ubiquitin specific peptidase 19 | 0.012 | ||
| Meis2 | Meis homeobox 2 | 0.012 | ||
| Sf1 | splicing factor 1 | 0.012 | ||
| Gnb5 | guanine nucleotide binding protein (G protein), beta 5 | 0.012 | ||
| LOC100361376 | rCG31687-like | 0.012 | ||
| Baat | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 0.012 | ||
| Gcgr | glucagon receptor | 0.012 | ||
| Pgap2 | post-GPI attachment to proteins 2 | 0.012 | ||
| Lrp3 | low density lipoprotein receptor-related protein 3 | 0.012 | ||
| Gstm7 | glutathione S-transferase, mu 7 | 0.012 | ||
| Stx2 | syntaxin 2 | 0.012 | ||
| Ddah1 | dimethylarginine dimethylaminohydrolase 1 | 0.012 | ||
| Bcam | basal cell adhesion molecule | 0.012 | ||
| Zfp469 | zinc finger protein 469 | 0.012 | ||
| Rad52 | RAD52 homolog (S. cerevisiae) | 0.012 | ||
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.012 | ||
| Syngr1 | synaptogyrin 1 | 0.012 | ||
| Cox8b | cytochrome c oxidase, subunit VIIIb | 0.011 | ||
| Irf2bp1 | interferon regulatory factor 2 binding protein 1 | 0.011 | ||
| Fto | fat mass and obesity associated | 0.011 | ||
| Arvcf | armadillo repeat gene deleted in velo-cardio-facial syndrome | 0.011 | ||
| Siat7F | sialyltransferase 7F | 0.011 | ||
| Cyp4b1 | cytochrome P450, family 4, subfamily b, polypeptide 1 | 0.011 | ||
| Wfs1 | Wolfram syndrome 1 homolog (human) | 0.011 | ||
| Jup | junction plakoglobin | 0.011 | ||
| Mgll | monoglyceride lipase | 0.011 | ||
| Lzts2 | leucine zipper, putative tumor suppressor 2 | 0.011 | ||
| Il9 | interleukin 9 | 0.011 | ||
| Myo18a | myosin XVIIIa | 0.011 | ||
| Ppard | peroxisome proliferator-activated receptor delta | 0.011 | ||
| A1cf | APOBEC1 complementation factor | 0.011 | ||
| Rgma | RGM domain family, member A | 0.011 | ||
| Pip4k2c | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma | 0.011 | ||
| Rarb | retinoic acid receptor, beta | 0.011 | ||
| Slc6a9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 0.011 | ||
| Abtb1 | ankyrin repeat and BTB (POZ) domain containing 1 | 0.011 | ||
| Btbd6 | BTB (POZ) domain containing 6 | 0.011 | ||
| Mlst8 | MTOR associated protein, LST8 homolog (S. cerevisiae) | 0.011 | ||
| Ppp1r3b | protein phosphatase 1, regulatory (inhibitor) subunit 3B | 0.011 | ||
| Rnf213 | ring finger protein 213 | 0.011 | ||
| Ppap2b | phosphatidic acid phosphatase type 2B | 0.011 | ||
| Zbtb7a | zinc finger and BTB domain containing 7a | 0.011 | ||
| Cnrip1 | cannabinoid receptor interacting protein 1 | 0.011 | ||
| Tcea3 | transcription elongation factor A (SII), 3 | 0.011 | ||
| Armc5 | armadillo repeat containing 5 | 0.011 | ||
| Mug1 | murinoglobulin 1 | 0.011 | ||
| Mapk12 | mitogen-activated protein kinase 12 | 0.011 | ||
| Dag1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.010 | ||
| Rasl10a | RAS-like, family 10, member A | 0.010 | ||
| Igfbp2 | insulin-like growth factor binding protein 2 | 0.010 | ||
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.010 | ||
| Kcnn2 | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 | 0.010 | ||
| Sparcl1 | SPARC-like 1 (hevin) | 0.010 | ||
| Apbb2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.010 | ||
| Pbx2 | pre-B-cell leukemia homeobox 2 | 0.010 | ||
| Pzp | pregnancy-zone protein | 0.010 | ||
| Aph1a | anterior pharynx defective 1 homolog A (C. elegans) | 0.010 | ||
| Ick | intestinal cell kinase | 0.010 | ||
| Map2k5 | mitogen activated protein kinase kinase 5 | 0.010 | ||
| Eif4ebp2 | eukaryotic translation initiation factor 4E binding protein 2 | 0.010 | ||
| Cyp4f1 | cytochrome P450, family 4, subfamily f, polypeptide 1 | 0.010 |