Saccharomyces cerevisiae

7 genes annotated in yeast

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peptidyl diphthamide biosynthetic process from peptidyl histidine

GO:0017183

The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.

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