IMP
Process View
error free translesion synthesis
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "error free translesion synthesis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| RAD5 | Rad5p | 0.693 | ||
| REV1 | Rev1p | 0.684 | ||
| REV7 | Rev7p | 0.648 | ||
| REV3 | Rev3p | 0.148 | ||
| RAD24 | Rad24p | 0.120 | ||
| RAD17 | Rad17p | 0.098 | ||
| RAD30 | Rad30p | 0.066 | ||
| MGS1 | Mgs1p | 0.056 | ||
| SHU1 | Shu1p | 0.051 | ||
| RAD18 | Rad18p | 0.048 | ||
| POL32 | Pol32p | 0.046 | ||
| APN1 | Apn1p | 0.046 | ||
| CDC9 | Cdc9p | 0.034 | ||
| RAD9 | Rad9p | 0.027 | ||
| PIF1 | Pif1p | 0.026 | ||
| SHU2 | Shu2p | 0.025 | ||
| SRD1 | Srd1p | 0.022 | ||
| RAD55 | Rad55p | 0.021 | ||
| LEU2 | Leu2p | 0.021 | ||
| EST2 | Est2p | 0.021 | ||
| YLR264C-A | hypothetical protein | 0.020 | ||
| YOL038C-A | hypothetical protein | 0.019 | ||
| PMS1 | Pms1p | 0.017 | ||
| ARP10 | Arp10p | 0.017 | ||
| MER1 | Mer1p | 0.017 | ||
| RNH203 | Rnh203p | 0.017 | ||
| UBC13 | Ubc13p | 0.017 | ||
| YLR162W | hypothetical protein | 0.016 | ||
| HXT3 | Hxt3p | 0.016 | ||
| YLR042C | hypothetical protein | 0.015 | ||
| MSH3 | Msh3p | 0.015 | ||
| ARG8 | Arg8p | 0.015 | ||
| SMC6 | Smc6p | 0.015 | ||
| YPR157W | hypothetical protein | 0.015 | ||
| YAR068W | hypothetical protein | 0.015 | ||
| WSS1 | Wss1p | 0.014 | ||
| ATP6 | Atp6p | 0.014 | ||
| CSM2 | Csm2p | 0.014 | ||
| HO | Hop | 0.014 | ||
| CUP1-1 | Cup1-1p | 0.013 | ||
| MF(ALPHA)2 | Mf(alpha)2p | 0.013 | ||
| AUA1 | Aua1p | 0.013 | ||
| RAD57 | Rad57p | 0.013 | ||
| DUN1 | Dun1p | 0.013 | ||
| HPF1 | Hpf1p | 0.013 | ||
| YLR126C | hypothetical protein | 0.013 | ||
| ZPS1 | Zps1p | 0.013 | ||
| YBR013C | hypothetical protein | 0.013 | ||
| YOL013W-A | hypothetical protein | 0.012 | ||
| CRP1 | Crp1p | 0.012 | ||
| POL3 | Pol3p | 0.012 | ||
| BSC1 | Bsc1p | 0.012 | ||
| PRS2 | Prs2p | 0.012 | ||
| URA3 | Ura3p | 0.012 | ||
| YKR075C | hypothetical protein | 0.011 | ||
| OPT2 | Opt2p | 0.011 | ||
| CHA1 | Cha1p | 0.011 | ||
| RAD10 | Rad10p | 0.011 | ||
| YLR040C | hypothetical protein | 0.011 | ||
| RNP1 | Rnp1p | 0.011 | ||
| FMT1 | Fmt1p | 0.011 | ||
| CPD1 | Cpd1p | 0.011 | ||
| DIC1 | Dic1p | 0.011 | ||
| NRG2 | Nrg2p | 0.011 | ||
| YAR066W | hypothetical protein | 0.011 | ||
| CUE2 | Cue2p | 0.011 | ||
| SPL2 | Spl2p | 0.011 | ||
| SWC7 | Swc7p | 0.011 | ||
| ZRT1 | Zrt1p | 0.011 | ||
| YIR035C | hypothetical protein | 0.011 | ||
| TYE7 | Tye7p | 0.011 | ||
| ADH2 | Adh2p | 0.011 | ||
| SCM4 | Scm4p | 0.011 | ||
| YGR079W | hypothetical protein | 0.010 | ||
| YPR096C | hypothetical protein | 0.010 | ||
| YPL067C | hypothetical protein | 0.010 | ||
| YAL037C-A | hypothetical protein | 0.010 | ||
| YDR222W | hypothetical protein | 0.010 | ||
| YAL064W | hypothetical protein | 0.010 |