IMP: Integrative Multi-species Prediction

Danio rerio

10 genes annotated in zebrafish

cofactor biosynthetic process

The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cofactor biosynthetic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cofactor biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
fech	ferrochelatase	0.987	Mouse
uros	uroporphyrinogen III synthase	0.959	Mouse
tfr1a	transferrin receptor 1a	0.951
slc25a37	solute carrier family 25, member 37	0.877
alas2	aminolevulinate, delta-, synthetase 2	0.701
gata1a	GATA binding protein 1a	0.614
slc4a1a	solute carrier family 4, anion exchanger, member 1a	0.546
ppox	protoporphyrinogen oxidase	0.307
klfd	Kruppel-like factor d	0.286
urod	uroporphyrinogen decarboxylase	0.271	Mouse
hbbe3	hemoglobin beta embryonic-3	0.263
slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	0.228
aco2	aconitase 2, mitochondrial	0.224
cox17	COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)	0.200
hmbsb	hydroxymethylbilane synthase, b	0.175
glrx5	glutaredoxin 5 homolog (S. cerevisiae)	0.163
znfl2a	zinc finger-like gene 2a	0.161
hbbe2	hemoglobin beta embryonic-2	0.137
aco1	aconitase 1, soluble	0.136
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.080
dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.077
hbae3	hemoglobin alpha embryonic-3	0.075
sucla2	succinate-CoA ligase, ADP-forming, beta subunit	0.072
chchd10	coiled-coil-helix-coiled-coil-helix domain containing 10	0.050
sdhb	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	0.049
hbaa1	hemoglobin alpha adult-1	0.044
atp5ib	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e, duplicate b	0.038
uqcrc1	ubiquinol-cytochrome c reductase core protein I	0.037
cyc1	cytochrome c-1	0.037
blvrb	biliverdin reductase B (flavin reductase (NADPH))	0.035
cmyb	transcription factor cmyb	0.031
pdcd8	programmed cell death 8 (apoptosis-inducing factor)	0.031
dlst	dihydrolipoamide S-succinyltransferase	0.026
iba57	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)	0.026
slmo2	slowmo homolog 2 (Drosophila)	0.026
LOC100151531	zinc finger protein Gfi-1b-like	0.025
hig1	hypoxia induced gene 1	0.025
hspa9	heat shock protein 9	0.025
zgc:56005	zgc:56005	0.024
hk2	hexokinase 2	0.021
klf4	Kruppel-like factor 4	0.020
zgc:73293	zgc:73293	0.020
uqcrb	ubiquinol-cytochrome c reductase binding protein	0.019
selt1a	selenoprotein T, 1a	0.019
mre11a	meiotic recombination 11 homolog A (S. cerevisiae)	0.019
stx3a	syntaxin 3A	0.019
kbp	kif1-binding protein	0.018
hdr	hematopoietic death receptor	0.017
dera	2-deoxyribose-5-phosphate aldolase homolog (C. elegans)	0.017
suclg1	succinate-CoA ligase, GDP-forming, alpha subunit	0.016
ogdh	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	0.016
mvp	major vault protein	0.016
zgc:154110	zgc:154110	0.016
nfe2	nuclear factor, erythroid-derived 2	0.015
zgc:163091	zgc:163091	0.015
brp44	brain protein 44	0.015
lhx1b	LIM homeobox 1b	0.014
lap3	leucine aminopeptidase 3	0.014
glipr2	GLI pathogenesis-related 2	0.014
pccb	propionyl Coenzyme A carboxylase, beta polypeptide	0.014
birc2	baculoviral IAP repeat-containing 2	0.014
exosc4	exosome component 4	0.014
zgc:63602	zgc:63602	0.014
slc25a3b	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b	0.014
zgc:158731	zgc:158731	0.014
slc25a11	solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11	0.014
zgc:110231	zgc:110231	0.013
glcci1	glucocorticoid induced transcript 1	0.013
ndufs7	NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)	0.013
tufm	Tu translation elongation factor, mitochondrial	0.013
sptb	spectrin, beta, erythrocytic	0.013	Mouse
asb11	ankyrin repeat and SOCS box-containing 11	0.012
vhl	von Hippel-Lindau tumor suppressor	0.012
mid1ip1b	MID1 interacting protein 1b	0.012
atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.012
itm2ba	integral membrane protein 2Ba	0.012
hibadha	3-hydroxyisobutyrate dehydrogenase a	0.012
lmnl3	lamin L3	0.012
zgc:111961	zgc:111961	0.012
pdha1a	pyruvate dehydrogenase (lipoamide) alpha 1a	0.012	Human
arfip2b	ADP-ribosylation factor interacting protein 2b	0.011
pdia5	protein disulfide isomerase family A, member 5	0.011
znhit1	zinc finger, HIT-type containing 1	0.011
dldh	dihydrolipoamide dehydrogenase	0.011
bscv	bscv (C20orf3) homolog	0.011
echdc2	enoyl CoA hydratase domain containing 2	0.011
bnip3lb	BCL2/adenovirus E1B interacting protein 3-like b	0.011
cldng	claudin g	0.011
cyfip2	cytoplasmic FMR1 interacting protein 2	0.011
hectd3	HECT domain containing 3	0.011
tie2	endothelium-specific receptor tyrosine kinase 2	0.011
pdap1	pdgfa associated protein 1	0.011
tsc1a	tuberous sclerosis 1a	0.011
ndufv1	NADH dehydrogenase (ubiquinone) flavoprotein 1	0.011
pigq	phosphatidylinositol glycan, class Q	0.011
zgc:77817	zgc:77817	0.011
trmt61a	tRNA methyltransferase 61 homolog A (S. cerevisiae)	0.011
zgc:101724	zgc:101724	0.011
smchd1	structural maintenance of chromosomes flexible hinge domain containing 1	0.011
ide	insulin-degrading enzyme	0.011
idh3b	isocitrate dehydrogenase 3 (NAD+) beta	0.011
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.010
sepx1a	selenoprotein X, 1a	0.010