IMP: Integrative Multi-species Prediction

Danio rerio

4 genes annotated in zebrafish

chondrocyte development

GO:0002063

The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "chondrocyte development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "chondrocyte development" (in gray)

Name	Description	Probability	Func Analog Organism
col5a1	procollagen, type V, alpha 1	0.915
col2a1a	collagen type II, alpha-1a	0.811
twist2	twist2	0.757
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.681
nkx3.2	NK3 homeobox 2	0.663
col11a2	collagen type XI alpha-2	0.641
sparc	secreted acidic cysteine rich glycoprotein	0.627
sulf1	sulfatase 1	0.578	Mouse
runx2b	runt-related transcription factor 2b	0.530	Mouse
dlx5a	distal-less homeobox gene 5a	0.473
dlx3b	distal-less homeobox gene 3b	0.470
col1a2	collagen, type I, alpha 2	0.468
col1a1a	collagen, type I, alpha 1a	0.421
notch2	notch homolog 2	0.400
bmper	BMP binding endothelial regulator	0.396
sulf2l	sulfatase 2, like	0.395	Mouse
runx2a	runt-related transcription factor 2a	0.361	Mouse
col10a1	collagen, type X, alpha 1	0.335
ctgf	connective tissue growth factor	0.301
wls	wntless homolog (Drosophila)	0.287
dcn	decorin	0.255
zgc:85838	zgc:85838	0.250
gsc	goosecoid	0.246
loxl3b	lysyl oxidase-like 3b	0.246
fgfrl1a	fibroblast growth factor receptor-like 1a	0.233
col11a1a	collagen, type XI, alpha 1a	0.221	Mouse
barx1	BarH-like homeobox 1	0.212
hoxa2b	homeo box A2b	0.208
nr2f1a	nuclear receptor subfamily 2, group F, member 1a	0.177
sox9b	SRY-box containing gene 9b	0.161
hapln1a	hyaluronan and proteoglycan link protein 1a	0.153
col27a1a	collagen, type XXVII, alpha 1a	0.151	Mouse
dlx2a	distal-less homeobox gene 2a	0.144
smad1	MAD homolog 1 (Drosophila)	0.136
papss2b	3'-phosphoadenosine 5'-phosphosulfate synthase 2b	0.133
id1	inhibitor of DNA binding 1	0.129
sulf2	sulfatase 2	0.119	Mouse
ptch2	patched 2	0.116
si:ch211-173b8.2	si:ch211-173b8.2	0.111
sema3d	semaphorin 3d	0.110
snai2	snail homolog 2 (Drosophila)	0.103
zgc:85866	zgc:85866	0.101
col5a2l	collagen, type V, alpha 2-like	0.091
slit3	slit (Drosophila) homolog 3	0.089
tbx2a	T-box gene 2a	0.089
fli1a	friend leukemia integration 1a	0.088
rcn3	reticulocalbin 3, EF-hand calcium binding domain	0.088
inka1a	induced in neural crest by AP2, 1a	0.084
lect1	leukocyte cell derived chemotaxin 1	0.083
xirp2a	xin actin-binding repeat containing 2a	0.079
LOC100000500	sclerostin-like	0.079
pdzrn3	PDZ domain containing RING finger 3 and PDZ domain containing ring finger 3	0.077
fstl1a	follistatin-like 1a	0.076
twist1a	twist1a	0.075
cart1	cartilage paired-class homeoprotein 1	0.075
bmpr2a	bone morphogenetic protein receptor, type II a (serine/threonine kinase)	0.075
hsp47	heat shock protein 47	0.073	Mouse
twist3	twist3	0.073
epyc	epiphycan	0.072
tp63	tumor protein p63	0.072
sdc2	syndecan 2	0.071
alpi	alkaline phosphatase, intestinal	0.068
col11a1b	collagen type XI alpha-1b and collagen, type XI, alpha 1b	0.066
neo1	neogenin 1	0.066
fzd7a	frizzled homolog 7a	0.065
fras1	Fraser syndrome 1	0.064
zgc:111821	zgc:111821	0.059
fzd2	frizzled homolog 2	0.057
pmp22a	peripheral myelin protein 22a	0.056
smad9	MAD homolog 9 (Drosophila)	0.055
frem3	Fras1 related extracellular matrix 3	0.055
tcf12	transcription factor 12	0.055
rasl11b	RAS-like, family 11, member B	0.055
thbs1	thrombospondin 1	0.054
fgfr2	fibroblast growth factor receptor 2	0.053
vasp	vasodilator-stimulated phosphoprotein	0.053
mmp2	matrix metalloproteinase 2	0.053
prrx1a	paired related homeobox 1a	0.051
pi4kb	phosphatidylinositol 4-kinase, catalytic, beta	0.051
sh3gl1b	SH3-domain GRB2-like 1b	0.051
cntfr	ciliary neurotrophic factor receptor	0.050
wnt11r	wingless-type MMTV integration site family, member 11, related	0.050
fgfr1b	fibroblast growth factor receptor 1b	0.049
sp7	Sp7 transcription factor	0.047
bmp2a	bone morphogenetic protein 2a	0.047
wu:fb16h09	wu:fb16h09	0.047
dlx4a	distal-less homeobox gene 4a	0.046
frzb	frizzled-related protein	0.046
rxraa	retinoid X receptor, alpha a	0.045
dlx4b	distal-less homeobox gene 4b	0.044
notum3	notum 3	0.044
boc	brother of CDO	0.044
twist1b	twist1b	0.043
plxnb2a	plexin b2a	0.042
wnt9b	wingless-type MMTV integration site family, member 9B	0.039
gli3	GLI-Kruppel family member GLI3	0.039
matn4	matrilin 4	0.039
col9a2	procollagen, type IX, alpha 2	0.038
acana	aggrecan a	0.038
klf2b	Kruppel-like factor 2b	0.037
ext1b	exostoses (multiple) 1b	0.037
il17rd	interleukin 17 receptor D	0.037
wnt5b	wingless-type MMTV integration site family, member 5b	0.037
ier5l	immediate early response 5-like	0.035
jam2b	junctional adhesion molecule 2b	0.035
angptl7	angiopoietin-like 7	0.035
si:dkey-261h17.1	si:dkey-261h17.1	0.035
wnt9a	wingless-type MMTV integration site family, member 9A	0.034
col9a3	collagen, type IX, alpha 3	0.034
LOC100536439	parathyroid hormone-related protein-like	0.033
nog1	noggin 1	0.032
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.032
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.032
mkxa	mohawk homeobox a	0.032
rcn1	reticulocalbin 1, EF-hand calcium binding domain	0.031
col1a1b	collagen, type I, alpha 1b	0.031
lrig1	leucine-rich repeats and immunoglobulin-like domains 1	0.031
fstl1b	follistatin-like 1b	0.031
postn	periostin, osteoblast specific factor	0.031
msxd	muscle segment homeobox D	0.030
pxn	paxillin	0.030
bmp7b	bone morphogenetic protein 7b	0.030
dfna5	deafness, autosomal dominant 5	0.029
col12a1	collagen, type XII, alpha 1	0.029
LOC556647	GDNF family receptor alpha-4-like	0.029
disc1	disrupted in schizophrenia 1	0.028
gng12a	guanine nucleotide binding protein (G protein), gamma 12a	0.028
gdf11	growth differentiation factor 11	0.027
satb2	SATB homeobox 2	0.027
si:xx-bac7cse.2	si:xx-bac7cse.2	0.027
vcanb	versican b	0.027
ehd2	EH-domain containing 2	0.027
mical3	flavoprotein oxidoreductase MICAL3	0.027
hmx2	H6 family homeobox 2	0.026
hmx3	homeo box (H6 family) 3	0.026
bglap	bone gamma-carboxyglutamate (gla) protein	0.026
s1pr2	sphingosine-1-phosphate receptor 2	0.026
ihha	Indian hedgehog homolog a	0.026
tcf21	transcription factor 21	0.026
mmp15b	matrix metallopeptidase 15b	0.026
si:ch211-212m21.5	si:ch211-212m21.5	0.025
tbx18	T-box 18	0.025
igf2a	insulin-like growth factor 2a	0.025
wu:fv91b12	wu:fv91b12	0.025
nphs2	nephrosis 2, idiopathic, steroid-resistant (podocin)	0.025
plod2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.025
p4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2	0.025
LOC565459	tight junction protein ZO-1-like	0.025
egfl6	EGF-like-domain, multiple 6	0.025
cyp1b1	cytochrome P450, family 1, subfamily B, polypeptide 1	0.024
mdkb	midkine-related growth factor b	0.023
cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.023
fgf16	fibroblast growth factor 16	0.023
fgf20b	fibroblast growth factor 20b	0.023
col14a1	collagen, type XIV, alpha 1	0.022
tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.022
lama5	laminin, alpha 5	0.022
hand2	heart and neural crest derivatives expressed transcript 2	0.022
ddx1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1	0.022
dlx6a	distal-less homeobox gene 6a	0.022
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.022
col15a1a	collagen, type XV, alpha 1a	0.021
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.021
fkbp10	FK506 binding protein 10	0.021
spry1	sprouty homolog 1 (Drosophila)	0.021
nog3	noggin 3	0.021
hoxb5b	homeo box B5b	0.021
hdac4	histone deacetylase 4	0.021
mcts1	malignant T cell amplified sequence 1	0.020
crip2	cysteine-rich protein 2	0.020
zgc:158603	zgc:158603	0.020
fam20b	family with sequence similarity 20, member B (H. sapiens)	0.020
epha4b	eph receptor A4b	0.020
mapk4	mitogen-activated protein kinase 4	0.020
hoxa3a	homeo box A3a	0.020
bmp3	bone morphogenetic protein 3	0.020
pax3a	paired box gene 3a	0.020
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.020
ptrfb	polymerase I and transcript release factor b	0.020
vcl	vinculin	0.020
gch2	GTP cyclohydrolase 2	0.019
zgc:85975	zgc:85975	0.019
b3gnt7	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7	0.019
hapln3	hyaluronan and proteoglycan link protein 3	0.019
gas1b	growth arrest-specific 1b	0.019
crabp2b	cellular retinoic acid binding protein 2, b	0.019
efnb3b	ephrin B3b	0.019
col27a1b	collagen, type XXVII, alpha 1b	0.019	Mouse
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.019
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.019
thbs4b	thrombospondin 4b	0.019
tbx15	T-box 15	0.018
pax3b	paired box gene 3b	0.018
msna	moesin a	0.018
lamb1a	laminin, beta 1a	0.018
vcp	valosin containing protein	0.018
fzd10	frizzled homolog 10	0.018
hsdl2	hydroxysteroid dehydrogenase like 2	0.018
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.018
sox9a	SRY-box containing gene 9a	0.018	Mouse
col6a3	collagen, type VI, alpha 3	0.017
nadl1.1	neural adhesion molecule L1.1	0.017
si:ch211-204c21.1	si:ch211-204c21.1	0.017
bmpr1ab	bone morphogenetic protein receptor, type 1ab	0.017
angpt1	angiopoietin 1	0.017
dtng	dystrobrevin, gamma and dystrobrevin, gamma-like	0.017
mgp	matrix Gla protein	0.017
edn1	endothelin 1	0.017
cdkrap3	CDK5 regulatory subunit associated protein 3	0.017
dpysl3	dihydropyrimidinase-like 3	0.017
vgll4l	vestigial like 4 like	0.017
sox11a	SRY-box containing gene 11a	0.017
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.016
alx4a	aristaless-like homeobox 4a	0.016
kirrela	kin of IRRE like a	0.016
cmn	calymmin	0.016
bhlhe41	basic helix-loop-helix family, member e41	0.016
myod1	myogenic differentiation 1	0.016
nbl1	neuroblastoma, suppression of tumorigenicity 1	0.016
jam3b	junctional adhesion molecule 3b	0.016
uxs1	UDP-glucuronic acid decarboxylase 1	0.016
ahr2	aryl hydrocarbon receptor 2	0.016
smoc2	secreted modular calcium binding protein 2	0.016
ugdh	UDP-glucose dehydrogenase	0.016
phf21a	PHD finger protein 21A	0.016
im:7150988	im:7150988	0.016
flrt3	fibronectin leucine rich transmembrane 3	0.016
sema3ab	semaphorin 3ab	0.016
hoxd13a	homeo box D13a	0.016
nrarpa	notch-regulated ankyrin repeat protein a	0.016
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.015
slc41a1	solute carrier family 41, member 1	0.015
nfybb	nuclear transcription factor Y, beta b	0.015
irgq1	immunity-related GTPase family, q1	0.015
lbx1a	ladybird homeobox 1a	0.015
chpf	chondroitin polymerizing factor	0.015
frem2a	Fras1 related extracellular matrix protein 2a	0.015
tnw	tenascin W	0.015
slc15a2	solute carrier family 15 (H+/peptide transporter), member 2	0.015
hoxa13b	homeo box A13b	0.015
mllt11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	0.015
hoxb2a	homeo box B2a	0.015
shdb	Src homology 2 domain containing transforming protein D, b	0.015
fgf4	fibroblast growth factor 4	0.015
and3	actinodin3	0.015
plagl2	pleiomorphic adenoma gene-like 2	0.015
p2rx3a	purinergic receptor P2X, ligand-gated ion channel, 3a	0.014
ufm1	ubiquitin-fold modifier 1	0.014
rbp4	retinol binding protein 4, plasma	0.014
wif1	wnt inhibitory factor 1	0.014
pax9	paired box gene 9	0.014
sox11b	SRY-box containing gene 11b	0.014
bambib	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b	0.014
git2b	G protein-coupled receptor kinase interactor 2b	0.014
zbtb4	zinc finger and BTB domain containing 4	0.014
ldb2b	LIM-domain binding factor 2b	0.014
utx	ubiquitously transcribed tetratricopeptide repeat, X chromosome	0.014
LOC100332904	hematopoietic progenitor cell antigen CD34-like	0.014
ihhb	Indian hedgehog homolog b	0.014
atf7a	activating transcription factor 7a	0.014
has3	hyaluronan synthase 3	0.014
copb2	coatomer protein complex, subunit beta 2	0.014
cdkl1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.014
axin2	axin 2 (conductin, axil)	0.014	Mouse
far1	fatty acyl CoA reductase 1	0.014
pdgfrl	platelet-derived growth factor receptor-like	0.014
rhoab	ras homolog gene family, member Ab	0.013
emilin3a	elastin microfibril interfacer 3a	0.013
spon1b	spondin 1b	0.013
arf1	ADP-ribosylation factor 1	0.013
pdlim3b	PDZ and LIM domain 3b	0.013
fmnl2a	formin-like 2a	0.013
ft1	alpha(1,3)fucosyltransferase gene 1	0.013
zgc:73290	zgc:73290	0.013
crispld1b	cysteine-rich secretory protein LCCL domain containing 1b	0.013
dpysl5a	dihydropyrimidinase-like 5a	0.013
sp8a	sp8 transcription factor a	0.013
hoxa5a	homeo box A5a	0.013
nrp1a	neuropilin 1a	0.013
fgfr3	fibroblast growth factor receptor 3	0.013
meis4.1a	myeloid ecotropic viral integration site 4.1a	0.013
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.013
zgc:92027	zgc:92027	0.013
si:dkey-97i18.2	si:dkey-97i18.2	0.013
gmppab	GDP-mannose pyrophosphorylase Ab	0.013
lrp5	low density lipoprotein receptor-related protein 5	0.013
ndufa9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9	0.013
runx3	runt-related transcription factor 3	0.013
si:ch73-60e21.1	si:ch73-60e21.1	0.012
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.012
pnx	posterior neuron-specific homeobox	0.012
col5a3	collagen, type V, alpha 3	0.012
epas1a	endothelial PAS domain protein 1a	0.012
nrarpb	notch-regulated ankyrin repeat protein b	0.012
plce1	phospholipase C, epsilon 1	0.012
pdlim7	PDZ and LIM domain 7	0.012
scinla	scinderin like a	0.012
sec13	SEC13 homolog (S. cerevisiae)	0.012
pcdh18a	protocadherin 18a	0.012
prickle1a	prickle-like 1 (Drosophila) a	0.012
prdm5	PR domain containing 5	0.012
sdf4	stromal cell derived factor 4	0.012
slc38a2	solute carrier family 38, member 2	0.012
si:ch211-266d19.3	si:ch211-266d19.3	0.012
col8a1a	collagen, type VIII, alpha 1a	0.012
gpr126	G protein-coupled receptor 126	0.012
mc5rb	melanocortin 5b receptor	0.012
wu:fj34h01	wu:fj34h01	0.012
zeb1	zinc finger E-box binding homeobox 1	0.012
emp2	epithelial membrane protein 2	0.012
bmp2b	bone morphogenetic protein 2b	0.012
copg2	coatomer protein complex, subunit gamma 2	0.011
ap1b1	adaptor-related protein complex 1, beta 1 subunit	0.011
cdh17	cadherin 17, LI cadherin (liver-intestine)	0.011
fgf20a	fibroblast growth factor 20a	0.011
spns2	spinster homolog 2 (Drosophila)	0.011
tjp2a	tight junction protein 2a (zona occludens 2)	0.011
foxd1	forkhead box D1	0.011
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.011
LOC567965	rho GTPase-activating protein 7-like	0.011
loxl2b	lysyl oxidase-like 2b	0.011
cmpk	cytidylate kinase	0.011
prkcbb	protein kinase C, beta b	0.011
sall1a	sal-like 1a (Drosophila)	0.011
ier2	immediate early response 2	0.011
cyp4t8	cytochrome P450, family 4, subfamily T, polypeptide 8	0.011
zgc:111878	zgc:111878	0.011
hs3st3b1b	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b	0.011
LOC100001665	hypothetical protein LOC100001665	0.011
chrna4	cholinergic receptor, nicotinic, alpha 4	0.011
LOC100148835	diacylglycerol kinase zeta-like	0.011
gpr133	G protein-coupled receptor 133	0.011
ube2h	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.011
serpinf1	serine (or cysteine) peptidase inhibitor, clade F, member 1	0.011
tpm4	tropomyosin 4	0.011
cd248b	CD248 molecule, endosialin b	0.011
tmem165	transmembrane protein 165	0.011
grk5	G protein-coupled receptor kinase 5	0.011
psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.011
bmp5	bone morphogenetic protein 5	0.011
atp1a1a.4	ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide	0.011
zgc:112042	zgc:112042	0.011
fzd7b	frizzled homolog 7b	0.011
barx2	BarH-like homeobox 2	0.011
fabp2	fatty acid binding protein 2, intestinal	0.011
akt2	v-akt murine thymoma viral oncogene homolog 2	0.011
rxrab	retinoid x receptor, alpha b	0.011
pmp22b	peripheral myelin protein 22b	0.011
capns1b	calpain, small subunit 1 b	0.010
zgc:101737	zgc:101737	0.010
hcst	hematopoietic cell signal transducer	0.010
acat2	acetyl-CoA acetyltransferase 2	0.010
zgc:85644	zgc:85644	0.010
cfdl	complement factor D (adipsin) like	0.010
snapc1b	small nuclear RNA activating complex, polypeptide 1b	0.010
tlr21	toll-like receptor 21	0.010
gng7	guanine nucleotide binding protein (G protein), gamma 7	0.010
foxp1b	forkhead box P1b	0.010
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.010
spon2a	spondin 2a, extracellular matrix protein	0.010
stab2	stabilin 2	0.010
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.010
tsku	tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)	0.010
yap1	Yes-associated protein 1	0.010
gale	UDP-galactose-4-epimerase	0.010
isl2a	islet2a	0.010
zgc:103467	myosin, light chain 9, regulatory	0.010
uncx4.1	Unc4.1 homeobox (C. elegans)	0.010
qars	glutaminyl-tRNA synthetase	0.010
lrig3	leucine-rich repeats and immunoglobulin-like domains 3	0.010
pdgfrb2	platelet derived growth factor receptor beta 2	0.010
tgfb1a	transforming growth factor, beta 1a	0.010
smoc1	SPARC related modular calcium binding 1	0.010
foxd3	forkhead box D3	0.010
bmp8a	bone morphogenetic protein 8a	0.010
msrb3	methionine sulfoxide reductase B3	0.010
zgc:101810	zgc:101810	0.010