IMP: Integrative Multi-species Prediction

Danio rerio

9 genes annotated in zebrafish

Multi-species View

positive regulation of purine nucleotide metabolic process

GO:1900544

Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in zebrafishInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of purine nucleotide metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of purine nucleotide metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.404
hsp90a.2	heat shock protein 90-alpha 2	0.329
mc3r	melanocortin 3 receptor	0.313	Human Zebrafish
bcl2	B-cell leukemia/lymphoma 2	0.273	Worm
adrb2a	adrenergic receptor, beta 2a	0.243
cnn2	calponin 2	0.222
pdlim1	PDZ and LIM domain 1 (elfin)	0.218
ncs1a	neuronal calcium sensor 1a	0.196	Fly
rtcd1	RNA terminal phosphate cyclase domain 1	0.190
tpm4	tropomyosin 4	0.180
rtn1a	reticulon 1a	0.152
mcl1b	myeloid cell leukemia sequence 1b	0.125	Worm
atp2b1a	ATPase, Ca++ transporting, plasma membrane 1a	0.114
hspa4a	heat shock protein 4a	0.105
bida	BH3 interacting domain death agonist	0.096
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.096
pvalb4	parvalbumin 4	0.078
pparg	peroxisome proliferator activated receptor gamma	0.077
mc5ra	melanocortin 5a receptor	0.075	Human Zebrafish
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.075
nf1a	neurofibromin 1a	0.074	Mouse Fly
gnaia	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a	0.074
cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.062
nf1b	neurofibromin 1b	0.061	Mouse Fly
jun	jun proto-oncogene	0.058	Human
rcn1	reticulocalbin 1, EF-hand calcium binding domain	0.058
cldnk	claudin k	0.055
atp2a1l	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like	0.055	Fly
gclc	glutamate-cysteine ligase, catalytic subunit	0.055
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.054
ahnak	AHNAK nucleoprotein	0.052
ywhai	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide	0.051
tagln2	transgelin 2	0.050
atp6v0cb	ATPase, H+ transporting, lysosomal, V0 subunit c, b	0.050
oxtl	oxytocin-like	0.049	Mouse
nme2b.2	non-metastatic cells 2b.2, protein (NM23B) expressed in	0.047
tomm34	translocase of outer mitochondrial membrane 34	0.047
pvalb1	parvalbumin 1	0.047
wnt10b	wingless-type MMTV integration site family, member 10b	0.046
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.042
rhag	Rhesus blood group-associated glycoprotein	0.041
mylz3	myosin, light polypeptide 3, skeletal muscle	0.041
hoxc12b	homeo box C12b	0.039
gnao1a	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a	0.038
si:ch211-232m7.1	si:ch211-232m7.1	0.037
ros1	v-ros UR2 sarcoma virus oncogene homolog 1 (avian)	0.037
or115-10	odorant receptor, family F, subfamily 115, member 10	0.037
ccng1	cyclin G1	0.036
rps6ka3a	ribosomal protein S6 kinase, polypeptide 3a	0.036
LOC559201	similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3)	0.035
pvalb3	parvalbumin 3	0.033
tpm3	tropomyosin 3	0.033
mc1r	melanocortin 1 receptor	0.032	Zebrafish
rhoaa	ras homolog gene family, member Aa	0.032
im:7137453	im:7137453	0.032
cldn12	claudin 12	0.032
zgc:162213	zgc:162213	0.031
aurka	aurora kinase A	0.030
atf3	activating transcription factor 3	0.030
vangl2	vang-like 2 (van gogh, Drosophila)	0.030
icn	ictacalcin	0.030
crb2a	crumbs homolog 2a	0.029
junbl	jun B proto-oncogene, like	0.028
rspo1	R-spondin homolog (Xenopus laevis)	0.028
dag1	dystroglycan 1	0.027
zgc:91930	zgc:91930	0.027
cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.027
phlda2	pleckstrin homology-like domain, family A, member 2	0.027
nedd4l	neural precursor cell expressed, developmentally down-regulated 4-like	0.026
abcf2	ATP-binding cassette, sub-family F (GCN20), member 2	0.026
dnaja1l	DnaJ (Hsp40) homolog, subfamily A, member 1, like	0.025	Yeast
cyp11b2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.025
socs3a	suppressor of cytokine signaling 3a	0.024
bcl2l1	bcl2-like 1	0.024	Worm
opn1lw1	opsin 1 (cone pigments), long-wave-sensitive, 1	0.023
nt5e	5'-nucleotidase, ecto (CD73)	0.023
flj13639	flj13639	0.022
trpc1	transient receptor potential cation channel, subfamily C, member 1	0.022
pvalb8	parvalbumin 8	0.022
ctsba	cathepsin B, a	0.022
anxa2a	annexin A2a	0.021
zgc:101724	zgc:101724	0.021
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.021
mcl1a	myeloid cell leukemia sequence 1a	0.021	Worm
rhoab	ras homolog gene family, member Ab	0.021
si:dkey-228g21.4	si:dkey-228g21.4	0.021
tnnt3b	troponin T3b, skeletal, fast	0.020
pvalb2	parvalbumin 2	0.020
ahctf1	AT hook containing transcription factor 1	0.020
nr0b1	nuclear receptor subfamily 0, group B, member 1	0.020
opn4l	opsin 4, like	0.020
fes	feline sarcoma oncogene	0.020
nrl	neural retina leucine zipper	0.020
cldni	claudin i	0.019
rpsa	ribosomal protein SA	0.019
mcm6	MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)	0.019
pak2a	p21 (CDKN1A)-activated kinase 2a	0.019
nras	neuroblastoma RAS viral (v-ras) oncogene homolog	0.019	Worm
scinlb	scinderin like b	0.019
cited3	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 3	0.019
inhbaa	inhibin, beta Aa	0.019
acvr1b	activin A receptor, type IB	0.019
myoz1b	myozenin 1b	0.019
cltca	clathrin, heavy polypeptide a (Hc)	0.018
dclk2	doublecortin-like kinase 2	0.018
dnmt7	DNA (cytosine-5-)-methyltransferase 7	0.018
atp1a1b	ATPase, Na+/K+ transporting, alpha 1b polypeptide	0.018
LOC565839	tumor necrosis factor alpha-induced protein 2-like	0.018
tert	telomerase reverse transcriptase	0.018
sox7	SRY-box containing gene 7	0.018
tsc22d3	TSC22 domain family, member 3	0.017
vim	vimentin	0.017
ndel1a	nudE nuclear distribution gene E homolog like 1 (A. nidulans) A	0.017	Mouse
avpl	arginine vasopressin-like	0.017	Mouse
rras	related RAS viral (r-ras) oncogene homolog	0.017	Yeast
smyd3	SET and MYND domain containing 3	0.017
atxn7l3	ataxin 7-like 3	0.017
nkx1.2la	NK1 transcription factor related 2-like,a	0.017
tes	testis derived transcript (3 LIM domains)	0.017
LOC100003330	melanocortin-2 receptor accessory protein 2-like	0.016
hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.016
si:dkey-233h2.3	si:dkey-233h2.3	0.016
lonp1	lon peptidase 1, mitochondrial	0.016
arpc5a	actin related protein 2/3 complex, subunit 5A	0.016
wu:fc23b05	wu:fc23b05	0.015
rtn1b	reticulon 1b	0.015
mpz	myelin protein zero	0.015
cldn2	claudin 2	0.015
zgc:55259	zgc:55259	0.015
tp73	tumor protein p73	0.015
cfdl	complement factor D (adipsin) like	0.015
zgc:66097	zgc:66097	0.015
zgc:63587	zgc:63587	0.015
pard3	par-3 partitioning defective 3 homolog (C. elegans)	0.015
slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.015
adipoql	adiponectin, C1Q and collagen domain containing, like	0.015
slc22a7b	solute carrier family 22 (organic anion transporter), member 7b	0.015
sox2	SRY-box containing gene 2	0.014
si:ch211-14k19.8	si:ch211-14k19.8	0.014
wu:fk76c08	wu:fk76c08	0.014
iqgap1	IQ motif containing GTPase activating protein 1	0.014
perp	PERP, TP53 apoptosis effector	0.014
mtp	microsomal triglyceride transfer protein	0.014
ccnb2	cyclin B2	0.014
pfn1	profilin 1	0.014
ywhaqb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b	0.014
fgf13b	fibroblast growth factor 13b	0.014
ptp4a1	protein tyrosine phosphatase type IVA, member 1	0.014
ccna2	cyclin A2	0.014
zgc:77517	zgc:77517	0.014
ehd1	EH-domain containing 1	0.014
baxb	bcl2-associated X protein, b	0.014	Worm
wu:fq26c12	wu:fq26c12	0.014
sinup	siaz-interacting nuclear protein	0.014
tm9sf2	transmembrane 9 superfamily member 2	0.014
adrb2b	adrenergic receptor, beta 2b	0.013
zgc:153129	zgc:153129	0.013
sec24c	SEC24 family, member C (S. cerevisiae)	0.013
mc5rb	melanocortin 5b receptor	0.013	Human
stmn1b	stathmin 1b	0.013
polr3b	polymerase (RNA) III (DNA directed) polypeptide B	0.012
neb	nebulin	0.012
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.012
cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.012
lingo1b	leucine rich repeat and Ig domain containing 1b	0.012
pgam2	phosphoglycerate mutase 2 (muscle)	0.012
cldnc	claudin c	0.012
gap43	growth associated protein 43	0.012
grk7a	G-protein-coupled receptor kinase 7a	0.012
lrrn1	leucine rich repeat neuronal 1	0.012
bactin2	bactin2	0.012
rapsn	receptor-associated protein of the synapse, 43kD	0.012
pccb	propionyl Coenzyme A carboxylase, beta polypeptide	0.012
dnmt5	DNA (cytosine-5-)-methyltransferase 5	0.012
ilk	integrin linked kinase	0.012
gfap	glial fibrillary acidic protein	0.012
rorb	RAR-related orphan receptor B	0.012
zgc:110010	zgc:110010	0.012
ckmb	creatine kinase, muscle b	0.012
ppme1	protein phosphatase methylesterase 1	0.012
boka	BCL2-related ovarian killer a	0.011	Worm
crb3b	crumbs homolog 3b	0.011
ampd3	adenosine monophosphate deaminase 3	0.011
ldb3b	LIM domain binding 3b	0.011
baxa	bcl2-associated X protein, a	0.011	Worm
drd3	dopamine receptor D3	0.011
slc25a4	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	0.011	Fly
ndrg3b	N-myc downstream regulated family member 3b	0.011
ints9	integrator complex subunit 9	0.011
clybl	citrate lyase beta-like	0.011
krml2.2	Kreisler (mouse) maf-related leucine zipper homolog 2.2	0.011
ndufa9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9	0.011
zgc:153997	zgc:153997	0.011
mknk2a	MAP kinase-interacting serine/threonine kinase 2a	0.011
sagb	S-antigen; retina and pineal gland (arrestin) b	0.010
si:ch211-156j22.4	si:ch211-156j22.4	0.010
acsl4a	acyl-CoA synthetase long-chain family member 4a	0.010
ap3m2	adaptor-related protein complex 3, mu 2 subunit	0.010
rab12	RAB12, member RAS oncogene family	0.010