IMP: Integrative Multi-species Prediction

Danio rerio

9 genes annotated in zebrafish

endocardium development

The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in zebrafishInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "endocardium development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "endocardium development" (in gray)

Name	Description	Probability	Func Analog Organism
tbx1	T-box 1	0.998
ptf1a	pancreas specific transcription factor, 1a	0.963	Zebrafish
fgf8a	fibroblast growth factor 8 a	0.925
cdh2	cadherin 2, neuronal	0.700
shha	sonic hedgehog a	0.657
pax2a	paired box gene 2a	0.654
tbx5a	T-box 5a	0.632
ptch1	patched 1	0.630
tp53	tumor protein p53	0.564
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.521
mib	mind bomb	0.519
lhx2b	LIM homeobox 2b	0.463
tbx16	T-box gene 16	0.396
fn1	fibronectin 1	0.388
wnt5b	wingless-type MMTV integration site family, member 5b	0.377
dlc	deltaC	0.340
zgc:111821	zgc:111821	0.301
twist1a	twist1a	0.284	Zebrafish
ptch2	patched 2	0.223
hnf1ba	HNF1 homeobox Ba	0.176
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.173
dla	deltaA	0.172
etv2	ets variant gene 2	0.168
tbx24	T-box 24	0.158
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.153
ndr2	nodal-related 2	0.145
sox9a	SRY-box containing gene 9a	0.141
kdrl	kinase insert domain receptor like	0.137
myl7	myosin, light polypeptide 7, regulatory	0.127
dld	deltaD	0.126
isl1	islet1	0.121
cdx4	caudal type homeo box transcription factor 4	0.120
myf5	myogenic factor 5	0.119
foxa2	forkhead box A2	0.116
bmp2b	bone morphogenetic protein 2b	0.114
gli1	GLI-Kruppel family member 1	0.109
aldoca	aldolase C, fructose-bisphosphate, a	0.104
tbx2b	T-box 2b	0.101
dzip1	DAZ interacting protein 1	0.096
lhx1b	LIM homeobox 1b	0.094
lmo2	LIM domain only 2 (rhombotin-like 1)	0.091
chd	chordin	0.090
tbx18	T-box 18	0.086
tie2	endothelium-specific receptor tyrosine kinase 2	0.082
runx1	runt-related transcription factor 1	0.082
gdf6a	growth differentiation factor 6a	0.081
gata1a	GATA binding protein 1a	0.078
rx3	retinal homeobox gene 3	0.072
dll4	delta-like 4 (Drosophila)	0.065
her1	hairy-related 1	0.063
atoh1b	atonal homolog 1b	0.062	Zebrafish
col2a1a	collagen type II, alpha-1a	0.059
mitfa	microphthalmia-associated transcription factor a	0.057
flt1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.056
scn8aa	sodium channel, voltage-gated, type VIII, alpha a	0.055
runx2b	runt-related transcription factor 2b	0.054
egr1	early growth response 1	0.052
hhex	hematopoietically expressed homeobox	0.052
neurod	neurogenic differentiation	0.052	Zebrafish
nppa	natriuretic peptide precursor A	0.050
atoh1a	atonal homolog 1a	0.048	Zebrafish
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.045
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.045
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.043
shhb	sonic hedgehog b	0.043
lamb1a	laminin, beta 1a	0.042
fli1a	friend leukemia integration 1a	0.040
six4a	sine oculis homeobox homolog 4a	0.040
foxa1	forkhead box A1	0.038
tbx20	T-box 20	0.038
jag1b	jagged 1b	0.036
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.036
fzd5	frizzled homolog 5	0.035
dbh	dopamine beta hydroxylase	0.035
tfap2a	transcription factor AP-2 alpha	0.033
myod1	myogenic differentiation 1	0.031
notch3	notch homolog 3	0.031
gad2	glutamate decarboxylase 2	0.028
trpv4	transient receptor potential cation channel, subfamily V, member 4	0.027
hlxb9la	homeo box HB9 like a	0.026
trim33	tripartite motif-containing 33	0.026
cdh5	cadherin 5	0.025
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.023
neurod6a	neurogenic differentiation 6a	0.022
chst11	carbohydrate (chondroitin 4) sulfotransferase 11	0.022
nkx2.2a	NK2 transcription factor related 2a	0.021
six2a	sine oculis-related homeobox 2a	0.021
fgf10a	fibroblast growth factor 10a	0.021
lpp	LIM domain containing preferred translocation partner in lipoma	0.021
gpc4	glypican 4	0.021
rx2	retinal homeobox gene 2	0.020
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.020
lhx1a	LIM homeobox 1a	0.020
cdh23	cadherin-like 23	0.019
has2	hyaluronan synthase 2	0.018
ntla	no tail a	0.018
prl	prolactin	0.018
sox9b	SRY-box containing gene 9b	0.018
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.018
cenph	centromere protein H	0.018
hoxa9b	homeo box A9b	0.017
gata5	GATA-binding protein 5	0.017
her7	hairy and enhancer of split related-7	0.017
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.017
gro2	groucho 2	0.016
atoh1c	atonal homolog 1c	0.016	Zebrafish
ext2	exostoses (multiple) 2	0.016
gata4	GATA-binding protein 4	0.016
neurod4	neurogenic differentiation 4	0.016	Zebrafish
rbfox1l	RNA binding protein, fox-1 homolog (C. elegans) 1-like	0.015
gro1	groucho 1	0.015
edn1	endothelin 1	0.015
bmp4	bone morphogenetic protein 4	0.015
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.015
osr2	odd-skipped related 2 (Drosophila)	0.015
hoxd10a	homeo box D10a	0.015
barhl2	BarH-like 2	0.014
hoxa2b	homeo box A2b	0.014
oep	one-eyed pinhead	0.014
aplnrb	apelin receptor b	0.014
hoxd11a	homeo box D11a	0.014
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.013
hhip	hedgehog interacting protein	0.013
pax6b	paired box gene 6b	0.013
ins	preproinsulin	0.013
foxi1	forkhead box I1	0.013
atp6v1b2	ATPase, H+ transporting, lysosomal V1 subunit B2	0.013
nkx2.5	NK2 transcription factor related 5	0.013
cadm2a	cell adhesion molecule 2a	0.013
hoxa13b	homeo box A13b	0.013
sox10	SRY-box containing gene 10	0.012
chga	chromogranin A	0.012
hoxa9a	homeo box A9a	0.012
sypb	synaptophysin b	0.012
slc8a1a	solute carrier family 8 (sodium/calcium exchanger), member 1a	0.012
kbp	kif1-binding protein	0.012
bmp10	bone morphogenetic protein 10	0.011
flt4	fms-related tyrosine kinase 4	0.011
chrnb3a	cholinergic receptor, nicotinic, beta polypeptide 3a	0.011
kita	kit receptor a	0.011
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.011
si:ch211-235f6.2	si:ch211-235f6.2	0.011
eya1	eyes absent homolog 1	0.011
nrp1a	neuropilin 1a	0.011
foxc1a	forkhead box C1a	0.011
pitx2	paired-like homeodomain transcription factor 2	0.011
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.010
vsx2	visual system homeobox 2	0.010
dmrt2a	doublesex and mab-3 related transcription factor 2a	0.010
fam20b	family with sequence similarity 20, member B (H. sapiens)	0.010
hmx4	H6 family homeobox 4	0.010
barx1	BarH-like homeobox 1	0.010