IMP: Integrative Multi-species Prediction

Danio rerio

106 genes annotated in zebrafish

enzyme linked receptor protein signaling pathway

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "enzyme linked receptor protein signaling pathway"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "enzyme linked receptor protein signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
chd	chordin	0.999
fgf8a	fibroblast growth factor 8 a	0.993	Mouse
sox9a	SRY-box containing gene 9a	0.983	Mouse
shha	sonic hedgehog a	0.967
ntla	no tail a	0.947
plcg1	phospholipase C, gamma 1	0.940	Human Fly
tbx1	T-box 1	0.928	Zebrafish
fgf3	fibroblast growth factor 3	0.926	Mouse Worm
ndr2	nodal-related 2	0.905
gli2a	GLI-Kruppel family member GLI2a	0.896
lft1	lefty1	0.895	Mouse
bmp4	bone morphogenetic protein 4	0.888
bmp2a	bone morphogenetic protein 2a	0.883	Human Zebrafish Mouse Rat Fly
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.858
twist3	twist3	0.837
bmp2b	bone morphogenetic protein 2b	0.830
pcdh18b	protocadherin 18b	0.813
wnt4a	wingless-type MMTV integration site family, member 4a	0.729	Zebrafish Mouse
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.722	Zebrafish
tbx16	T-box gene 16	0.703
gli1	GLI-Kruppel family member 1	0.688
vcana	versican a	0.674
dusp6	dual specificity phosphatase 6	0.661
fn1	fibronectin 1	0.656
raraa	retinoic acid receptor, alpha a	0.647	Zebrafish
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.640
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.613
s1pr2	sphingosine-1-phosphate receptor 2	0.611
notch1a	notch homolog 1a	0.609	Mouse
efnb2a	ephrin B2a	0.592	Human Worm
vent	ventral expressed homeobox	0.589
gpc4	glypican 4	0.586
notch3	notch homolog 3	0.580
gbx2	gastrulation brain homeo box 2	0.578
fzd10	frizzled homolog 10	0.570
ephb4b	eph receptor B4b	0.564	Human Mouse
smad9	MAD homolog 9 (Drosophila)	0.559	Zebrafish Mouse Fly
dlc	deltaC	0.544	Zebrafish
esr1	estrogen receptor 1	0.526	Rat
trim33	tripartite motif-containing 33	0.522	Human
wnt5b	wingless-type MMTV integration site family, member 5b	0.519	Zebrafish Mouse
tie1	endothelium-specific receptor tyrosine kinase 1	0.511
gata4	GATA-binding protein 4	0.510	Zebrafish Mouse
foxa3	forkhead box A3	0.509
rag1	recombination activating gene 1	0.501
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.498
runx2b	runt-related transcription factor 2b	0.497	Mouse
spns2	spinster homolog 2 (Drosophila)	0.490	Fly
dlb	deltaB	0.490	Zebrafish
fsta	follistatin a	0.478	Human Zebrafish Mouse
wnt10a	wingless-type MMTV integration site family, member 10a	0.467	Zebrafish
fbn2b	fibrillin 2b	0.466
sox7	SRY-box containing gene 7	0.465
foxi1	forkhead box I1	0.461
bmp7a	bone morphogenetic protein 7a	0.460
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.456	Fly
fgfr1b	fibroblast growth factor receptor 1b	0.454	Human Zebrafish Mouse Worm
igf1rb	insulin-like growth factor 1b receptor	0.454
nanos3	nanos homolog 3	0.449
zbtb4	zinc finger and BTB domain containing 4	0.447
tbx2a	T-box gene 2a	0.444	Zebrafish
sox19a	SRY-box containing gene 19a	0.435
wnt8b	wingless-type MMTV integration site family, member 8b	0.431	Zebrafish
wnt11r	wingless-type MMTV integration site family, member 11, related	0.417	Zebrafish
sec23a	Sec23 homolog A (S. cerevisiae)	0.414
cmyb	transcription factor cmyb	0.400
tll1	tolloid-like 1	0.398
wnt11	wingless-type MMTV integration site family, member 11	0.397	Zebrafish
pomca	proopiomelanocortin a	0.396
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.395
twist1a	twist1a	0.391
egr1	early growth response 1	0.391	Mouse
neo1	neogenin 1	0.388	Mouse Worm
nog2	noggin 2	0.385
eve1	even-skipped-like1	0.381
fras1	Fraser syndrome 1	0.379
ptch2	patched 2	0.377
ghra	growth hormone receptor a	0.376	Human Mouse Rat
dcc	deleted in colorectal carcinoma	0.375
eomesa	eomesodermin homolog a	0.374	Zebrafish
esr2a	estrogen receptor 2a	0.373	Rat
wnt9a	wingless-type MMTV integration site family, member 9A	0.363	Zebrafish
pkd2	polycystic kidney disease 2	0.363
rarab	retinoic acid receptor, alpha b	0.354	Zebrafish
zgc:85866	zgc:85866	0.351	Human Zebrafish
fgfr2	fibroblast growth factor receptor 2	0.351	Human Zebrafish Mouse Rat Worm
hoxa13a	homeo box A13a	0.345	Mouse
spry4	sprouty (Drosophila) homolog 4	0.343
hhip	hedgehog interacting protein	0.333	Mouse
tp53bp2	tumor protein p53 binding protein, 2	0.326
cdh5	cadherin 5	0.326
fmr1	fragile X mental retardation 1	0.323	Fly
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.322
nrp2b	neuropilin 2b	0.319
hs6st2	heparan sulfate 6-O-sulfotransferase 2	0.317	Fly
mecom	MDS1 and EVI1 complex locus	0.317
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.315
tbx18	T-box 18	0.315	Zebrafish
gbx1	gastrulation brain homeobox 1	0.312
ptk2.1	protein tyrosine kinase 2a	0.312	Human Fly
mbtps1	membrane-bound transcription factor protease, site 1	0.310
ccm2	cerebral cavernous malformation 2	0.309
nadl1.1	neural adhesion molecule L1.1	0.308
nkx2.5	NK2 transcription factor related 5	0.307
dharma	dharma	0.305
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.302
egr2b	early growth response 2b	0.302
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.299
osr1	odd-skipped related 1 (Drosophila)	0.299
otx1b	orthodenticle homolog 1b	0.298
etv5b	ets variant 5b	0.296
hdac4	histone deacetylase 4	0.296
wnt3a	wingless-type MMTV integration site family, member 3A	0.294	Zebrafish
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.293
pcdh10b	protocadherin 10b	0.292
flt4	fms-related tyrosine kinase 4	0.291
boc	brother of CDO	0.291
LOC100000687	signal peptide, CUB and EGF-like domain-containing protein 3-like	0.289
pitx3	paired-like homeodomain transcription factor 3	0.285
wnt9b	wingless-type MMTV integration site family, member 9B	0.285	Zebrafish
fabp11a	fatty acid binding protein 11a	0.285
fgf4	fibroblast growth factor 4	0.280	Human Mouse Worm
mab21l2	mab-21-like 2	0.279
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.276	Fly
prkcz	protein kinase C, zeta	0.275	Human Rat
mapk3	mitogen-activated protein kinase 3	0.272	Human Fly
tbx20	T-box 20	0.271	Zebrafish Mouse
hoxb2a	homeo box B2a	0.267
dld	deltaD	0.267	Zebrafish
zgc:111821	zgc:111821	0.264
znf703	zinc finger protein 703	0.262	Human
sulf2	sulfatase 2	0.262	Mouse Fly
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.261
gdf6a	growth differentiation factor 6a	0.260
lft2	lefty2	0.260	Mouse
ptch1	patched 1	0.259
junb	jun B proto-oncogene	0.259
zeb1	zinc finger E-box binding homeobox 1	0.256	Zebrafish Mouse
foxg1a	forkhead box G1a	0.253
runx2a	runt-related transcription factor 2a	0.253	Mouse
rasl11b	RAS-like, family 11, member B	0.252
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.246	Human Zebrafish Mouse Fly
sfrp5	secreted frizzled-related protein 5	0.245
vegfc	vascular endothelial growth factor c	0.245
nadl1.2	neural adhesion molecule L1.2	0.240
nog3	noggin 3	0.238
s1pr1	sphingosine-1-phosphate receptor 1	0.236
ldb2a	LIM-domain binding factor 2a	0.235
tal1	T-cell acute lymphocytic leukemia 1	0.235
fgfr1a	fibroblast growth factor receptor 1a	0.233
sgk1	serum/glucocorticoid regulated kinase 1	0.233
twist1b	twist1b	0.232
otx2	orthodenticle homolog 2	0.230
kif5bb	kinesin family member 5B, b	0.229
atoh7	atonal homolog 7	0.228	Fly
six4b	sine oculis homeobox homolog 4b	0.226
sox11a	SRY-box containing gene 11a	0.226
vsx1	visual system homeobox 1 homolog, chx10-like	0.223
nipblb	novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)	0.222
tsc22d3	TSC22 domain family, member 3	0.221
odc1	ornithine decarboxylase 1	0.221
lfng	lunatic fringe homolog	0.219
igf1ra	insulin-like growth factor 1a receptor	0.219
ier2	immediate early response 2	0.217
tm4sf4	transmembrane 4 L six family member 4	0.215
erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog	0.215	Human
mapk1	mitogen-activated protein kinase 1	0.212	Human Fly
flh	floating head	0.211
amotl2a	angiomotin like 2a	0.210
hmx1	H6 homeo box 1	0.210
mpz	myelin protein zero	0.208
pou5f1	POU domain, class 5, transcription factor 1	0.207
nort	notch-regulated transcript	0.207
efna2	ephrin A2	0.207	Mouse Worm
cdh1	cadherin 1, epithelial	0.207	Human
wu:fv91b12	wu:fv91b12	0.206
pdgfaa	platelet-derived growth factor alpha a	0.206	Human
csrnp1b	cysteine-serine-rich nuclear protein 1b	0.205	Mouse
acvr1l	activin A receptor, type I like	0.204
btg2	B-cell translocation gene 2	0.203
fzd8a	frizzled homolog 8a	0.203
jag2	jagged 2	0.202	Zebrafish
rasgef1ba	RasGEF domain family, member 1Ba	0.202
ved	ventrally expressed dharma/bozozok antagonist	0.202
gng3	guanine nucleotide binding protein (G protein), gamma 3	0.200	Zebrafish
pax6a	paired box gene 6a	0.200	Fly
lmo4a	LIM domain only 4a	0.200
jun	jun proto-oncogene	0.198	Human
gata3	GATA-binding protein 3	0.196
metrn	meteorin, glial cell differentiation regulator	0.195
vcanb	versican b	0.195
rxrba	retinoid x receptor, beta a	0.195
klf4a	Kruppel-like transcription factor 4a	0.194
ephb4a	eph receptor B4a	0.193	Human Mouse
appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	0.193
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.191	Mouse
psen1	presenilin 1	0.191	Mouse Worm
glula	glutamate-ammonia ligase (glutamine synthase) a	0.190
tshb	thyroid stimulating hormone, beta subunit	0.190
jag1b	jagged 1b	0.189	Zebrafish
brd4	bromodomain containing 4	0.189
aldh1a3	aldehyde dehydrogenase 1 family, member A3	0.186
gro1	groucho 1	0.186
ptpra	protein tyrosine phosphatase, receptor type, A	0.184	Mouse Worm
dusp1	dual specificity phosphatase 1	0.183	Zebrafish
ctnnd2b	catenin (cadherin-associated protein), delta 2b	0.182
fzd8b	frizzled homolog 8b	0.181
hlxb9la	homeo box HB9 like a	0.181
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.180
tyr	tyrosinase	0.180
gdnf	glial cell derived neurotrophic factor	0.179
rarga	retinoic acid receptor gamma a	0.178	Zebrafish
smad1	MAD homolog 1 (Drosophila)	0.178
lef1	lymphocyte enhancer binding factor 1	0.178	Mouse
hbbe1.1	hemoglobin beta embryonic-1.1	0.177
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.177
hdlbp	high density lipoprotein-binding protein (vigilin)	0.176
frzb	frizzled-related protein	0.175
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.175
tpbgl	trophoblast glycoprotein-like	0.174
pax7a	paired box gene 7a	0.174
foxc1a	forkhead box C1a	0.172
hmx4	H6 family homeobox 4	0.170
snai1b	snail homolog 1b (Drosophila)	0.170
hif1ab	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b	0.168	Mouse
zeb2a	zinc finger E-box binding homeobox 2a	0.167
fgfr3	fibroblast growth factor receptor 3	0.167	Human Zebrafish Mouse Worm
her6	hairy-related 6	0.166
kirrela	kin of IRRE like a	0.165
igfbp1b	insulin-like growth factor binding protein 1b	0.165	Zebrafish Rat
arhgef7b	Rho guanine nucleotide exchange factor (GEF) 7b	0.163
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.163
acvr2a	activin receptor IIa	0.163	Human Mouse Rat
si:ch211-235f6.2	si:ch211-235f6.2	0.163
maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)	0.163
igf1	insulin-like growth factor 1	0.162
pcdh18a	protocadherin 18a	0.162
mtmr8	myotubularin related protein 8	0.162
lect1	leukocyte cell derived chemotaxin 1	0.162	Mouse
smoc1	SPARC related modular calcium binding 1	0.161
cyp1a	cytochrome P450, family 1, subfamily A	0.160
vox	ventral homeobox	0.160
insm1a	insulinoma-associated 1a	0.160
cadm1b	cell adhesion molecule 1b	0.159
ntn1b	netrin 1b	0.159
fn1b	fibronectin 1b	0.159
sox32	SRY-box containing gene 32	0.158
gngt2b	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b	0.158
crabp2a	cellular retinoic acid binding protein 2, a	0.158
rxrbb	retinoid x receptor, beta b	0.157
aox3	aldehyde oxidase 3	0.156
pcdh19	protocadherin 19	0.155
foxo3b	forkhead box O3b	0.155	Worm Fly
cdx4	caudal type homeo box transcription factor 4	0.154
apoeb	apolipoprotein Eb	0.153
slc25a37	solute carrier family 25, member 37	0.153
runx1	runt-related transcription factor 1	0.151
six2a	sine oculis-related homeobox 2a	0.150
sox1a	SRY-box containing gene 1a	0.149
ca8	carbonic anhydrase VIII	0.149
gata5	GATA-binding protein 5	0.148	Zebrafish
her11	hairy-related 11	0.148
olfm2	olfactomedin 2	0.145
smad5	MAD homolog 5 (Drosophila)	0.144
slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.144
mef2a	myocyte enhancer factor 2a	0.143
sox9b	SRY-box containing gene 9b	0.142
ihha	Indian hedgehog homolog a	0.142	Zebrafish Fly
disp1	dispatched homolog 1 (Drosophila)	0.142
cyp1b1	cytochrome P450, family 1, subfamily B, polypeptide 1	0.142
zgc:55813	zgc:55813	0.141
il17rd	interleukin 17 receptor D	0.141
etv5a	ets variant 5a	0.140
aplp2	amyloid beta (A4) precursor-like protein 2	0.140	Mouse
midn	midnolin	0.140
edn1	endothelin 1	0.140
im:7162646	im:7162646	0.140
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.138	Zebrafish
her8a	hairy-related 8a	0.138
irx1b	iroquois homeobox protein 1, b	0.138
crestin	crestin	0.138
grnb	granulin b	0.137
foxa2	forkhead box A2	0.136
fgf17	fibroblast growth factor 17	0.136	Mouse
gdf9	growth differentiation factor 9	0.134
gsc	goosecoid	0.133	Zebrafish
oep	one-eyed pinhead	0.133
dcst1	DC-STAMP domain containing 1	0.133
hhex	hematopoietically expressed homeobox	0.133
pvalb7	parvalbumin 7	0.133
sec24c	SEC24 family, member C (S. cerevisiae)	0.132
wif1	wnt inhibitory factor 1	0.132
dlx5a	distal-less homeobox gene 5a	0.132	Mouse
hoxa13b	homeo box A13b	0.132	Mouse
bmp15	bone morphogenetic protein 15	0.132	Zebrafish
rx3	retinal homeobox gene 3	0.132
zgc:114095	zgc:114095	0.131
sox17	SRY-box containing gene 17	0.131
cdkn1a	cyclin-dependent kinase inhibitor 1A	0.129
bmp7b	bone morphogenetic protein 7b	0.128	Human Zebrafish Mouse
pax6b	paired box gene 6b	0.127	Fly
ankrd6	ankyrin repeat domain 6	0.126
dkk1b	dickkopf 1b	0.126	Mouse
etv2	ets variant gene 2	0.125
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.125
cp	ceruloplasmin	0.125
etf1	eukaryotic translation termination factor 1	0.125
th	tyrosine hydroxylase	0.124
LOC566708	FL cytokine receptor-like	0.124
col7a1l	collagen type VII alpha 1-like	0.124
ntrk2b	neurotrophic tyrosine kinase, receptor, type 2b	0.123	Human Mouse Rat
si:dkeyp-104h9.6	si:dkeyp-104h9.6	0.123
nrg2a	neuregulin 2a	0.122
col4a5	collagen, type IV, alpha 5 (Alport syndrome)	0.122
im:7137555	im:7137555	0.121
her1	hairy-related 1	0.121
pax9	paired box gene 9	0.121
zmynd11	zinc finger, MYND domain containing 11	0.121
drl	draculin	0.120
fzd5	frizzled homolog 5	0.120
vax1	ventral anterior homeobox 1	0.120
nrp2a	neuropilin 2a	0.119
irx5a	iroquois homeobox protein 5a	0.118
hmcn1	hemicentin 1	0.118
nras	neuroblastoma RAS viral (v-ras) oncogene homolog	0.118	Worm
cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.118
nkx3.2	NK3 homeobox 2	0.118
otx5	orthodenticle homolog 5	0.116
gng7	guanine nucleotide binding protein (G protein), gamma 7	0.115	Zebrafish Mouse
isl1	islet1	0.114	Fly
unc45a	unc-45 homolog A (C. elegans)	0.113
card14	caspase recruitment domain family, member 14	0.113
zic5	zic family member 5 (odd-paired homolog, Drosophila)	0.113	Fly
fgf24	fibroblast growth factor 24	0.112
sirt1	sirtuin (silent mating type information regulation 2 homolog) 1	0.112
kdrl	kinase insert domain receptor like	0.112	Zebrafish
msxc	muscle segment homeobox C	0.111
kitlga	kit ligand a	0.111
six4.3	sine oculis homeobox homolog 4.3	0.111
per2	period homolog 2 (Drosophila)	0.110
im:7165141	im:7165141	0.110
fabp10a	fatty acid binding protein 10a, liver basic	0.109
gclc	glutamate-cysteine ligase, catalytic subunit	0.109
prl	prolactin	0.109
npepps	aminopeptidase puromycin sensitive	0.108
aplnrb	apelin receptor b	0.108
lin28a	lin-28 homolog A (C. elegans)	0.108
bnc2	basonuclin 2	0.108
mapk4	mitogen-activated protein kinase 4	0.107
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.107	Fly
opn4x1	opsin 4x1	0.107
dscam	Down syndrome cell adhesion molecule	0.106
her4.5	hairy-related 4.5	0.106
egr2a	early growth response 2a	0.106
cyp26a1	cytochrome P450, subfamily XXVIA, polypeptide 1	0.105
robo4	roundabout homolog 4	0.104
dacha	dachshund a	0.104
gli2b	GLI-Kruppel family member GLI2b	0.104
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.104
mycbp2	MYC binding protein 2	0.104	Fly
tsen54	tRNA splicing endonuclease 54 homolog (S. cerevisiae)	0.103
arl4ab	ADP-ribosylation factor-like 4ab	0.103
fgf8b	fibroblast growth factor 8 b	0.103	Human Mouse
mtp	microsomal triglyceride transfer protein	0.103
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.102
atm	ataxia telangiectasia mutated	0.101
prdm5	PR domain containing 5	0.101
sulf1	sulfatase 1	0.101	Human Mouse Fly
ctsl1b	cathepsin L, 1 b	0.101
chrna6	cholinergic receptor, nicotinic, alpha 6	0.101
six3a	sine oculis homeobox homolog 3a	0.100
alk	anaplastic lymphoma kinase (Ki-1)	0.100
dlg2	discs, large (Drosophila) homolog 2	0.100
nkx6.2	NK6 transcription factor related, locus 2	0.100
stab2	stabilin 2	0.100
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.099
shhb	sonic hedgehog b	0.099	Zebrafish Fly
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.099
frmd6	FERM domain containing 6	0.099
cited3	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 3	0.099
elovl4b	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4b	0.098
vasa	vasa homolog	0.098
sgpp1	sphingosine-1-phosphate phosphatase 1	0.098
col9a2	procollagen, type IX, alpha 2	0.097
nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.096
ldb1a	LIM-domain binding factor 1a	0.096
hoxa1a	homeo box A1a	0.096
paqr7b	progestin and adipoQ receptor family member VII, b	0.096
smo	smoothened homolog (Drosophila)	0.096
frem2a	Fras1 related extracellular matrix protein 2a	0.095
ephb3a	eph receptor B3a	0.095	Human
zgc:64114	zgc:64114	0.095
sox5	SRY-box containing gene 5	0.095
nrarpa	notch-regulated ankyrin repeat protein a	0.094
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.094
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.094
ulk2	unc-51-like kinase 2 (C. elegans)	0.094
hgd	homogentisate 1,2-dioxygenase	0.094
lhx2b	LIM homeobox 2b	0.094
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.094
klf2a	Kruppel-like factor 2a	0.094
clint1	clathrin interactor 1	0.094
stat5.1	signal transducer and activator of transcription 5.1	0.093	Human Mouse
si:dkeyp-50f5.1	si:dkeyp-50f5.1	0.093
celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	0.093
arrb2b	arrestin, beta 2b	0.093	Human
stmn2a	stathmin-like 2a	0.093
prdm1a	PR domain containing 1a, with ZNF domain	0.093
hoxb1a	homeo box B1a	0.093
rargb	retinoic acid receptor, gamma b	0.092
smyhc1	slow myosin heavy chain 1	0.092	Mouse
appa	amyloid beta (A4) precursor protein a	0.092	Mouse
sesn1	sestrin 1	0.091
myca	myelocytomatosis oncogene a	0.090
wnt1	wingless-type MMTV integration site family, member 1	0.090	Human Zebrafish Mouse
col12a1	collagen, type XII, alpha 1	0.090
hand2	heart and neural crest derivatives expressed transcript 2	0.090
gata6	GATA-binding protein 6	0.089
spon2a	spondin 2a, extracellular matrix protein	0.089
fgf20a	fibroblast growth factor 20a	0.089	Worm
tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.088
hsd17b3	hydroxysteroid (17-beta) dehydrogenase 3	0.088
tbx2b	T-box 2b	0.088	Zebrafish
fgfr4	fibroblast growth factor receptor 4	0.088	Human Zebrafish Mouse Rat Worm
adora2b	adenosine A2b receptor	0.088
rspo1	R-spondin homolog (Xenopus laevis)	0.088
sema3fb	semaphorin 3fb	0.087
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.087
bmp3	bone morphogenetic protein 3	0.087	Zebrafish
nr5a1b	nuclear receptor subfamily 5, group A, member 1b	0.087
wnt2	wingless-type MMTV integration site family member 2	0.087	Zebrafish
nkx2.1a	NK2 homeobox 1a	0.087
myhz2	myosin, heavy polypeptide 2, fast muscle specific	0.087
sox19b	SRY-box containing gene 19b	0.086
ncor1	nuclear receptor co-repressor 1	0.086
otpb	orthopedia homolog b	0.086
cenph	centromere protein H	0.086
ncoa2	nuclear receptor coactivator 2	0.086
osr2	odd-skipped related 2 (Drosophila)	0.085
socs3a	suppressor of cytokine signaling 3a	0.085	Mouse
zfyve26	zinc finger, FYVE domain containing 26	0.084
neurod6b	neurogenic differentiation 6b	0.084
si:ch211-173o4.2	si:ch211-173o4.2	0.084
socs3b	suppressor of cytokine signaling 3b	0.084	Mouse
dtng	dystrobrevin, gamma and dystrobrevin, gamma-like	0.084
camk2a	calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha	0.084
nrp1a	neuropilin 1a	0.083
waca	WW domain containing adaptor with coiled-coil a	0.083
kal1b	Kallmann syndrome 1b sequence	0.083
chrm2a	cholinergic receptor, muscarinic 2a	0.083
plagl2	pleiomorphic adenoma gene-like 2	0.083
fryl	furry homolog-like (Drosophila)	0.083
unc5c	unc-5 homolog C (C. elegans)	0.083
chd7	chromodomain helicase DNA binding protein 7	0.083
plp1a	proteolipid protein 1a	0.083
mapk12	mitogen-activated protein kinase 12	0.082	Fly
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.082
st8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.082
oprm1	opioid receptor, mu 1	0.082
vipr2	vasoactive intestinal peptide receptor 2	0.082
mbnl2	muscleblind-like 2 (Drosophila)	0.082
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.081
sp2	sp2 transcription factor	0.081
csnk1da	casein kinase 1, delta a	0.081
tgfb3	transforming growth factor, beta 3	0.081	Human Mouse Rat
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.081	Zebrafish
lbx1a	ladybird homeobox 1a	0.081
egfra	epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	0.080	Human Mouse
lhx1b	LIM homeobox 1b	0.080
dusp2	dual specificity phosphatase 2	0.080	Zebrafish
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.080
dzip1	DAZ interacting protein 1	0.080
dmrt3a	doublesex and mab-3 related transcription factor 3a	0.080
aplnra	apelin receptor a	0.080
tob1a	transducer of ERBB2, 1a	0.079
tp63	tumor protein p63	0.079	Fly
zgc:165373	zgc:165373	0.079
cdh2	cadherin 2, neuronal	0.078
six3b	sine oculis homeobox homolog 3b	0.078
mmp9	matrix metalloproteinase 9	0.078
runx3	runt-related transcription factor 3	0.077
sepp1a	selenoprotein P, plasma, 1a	0.077
spry2	sprouty homolog 2	0.077
pax2a	paired box gene 2a	0.077
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.077
zgc:101761	zgc:101761	0.077
npdc1	neural proliferation, differentiation and control, 1	0.076
gcga	glucagon a and glucagon a-like	0.076
atf3	activating transcription factor 3	0.076
met	met proto-oncogene (hepatocyte growth factor receptor)	0.076
arg2	arginase, type II	0.075
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.075
lmo7a	LIM domain only 7a	0.075
fgf10a	fibroblast growth factor 10a	0.075	Mouse Worm
id:ibd2573	id:ibd2573	0.075
robo1	roundabout homolog 1	0.075
col10a1	collagen, type X, alpha 1	0.075
lrrc6	leucine rich repeat containing 6	0.075
unc5b	unc-5 homolog B (C. elegans)	0.075
si:ch211-241e15.2	si:ch211-241e15.2	0.074
gng13b	guanine nucleotide binding protein (G protein), gamma 13b	0.074	Zebrafish
nf1a	neurofibromin 1a	0.073
foxi3b	forkhead box I3b	0.073
bmpr1ab	bone morphogenetic protein receptor, type 1ab	0.073
mespb	mesoderm posterior b	0.073
lhcgr	luteinizing hormone/choriogonadotropin receptor	0.073
cyp24a1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.073
nr4a1	nuclear receptor subfamily 4, group A, member 1	0.073
si:ch211-285f17.1	si:ch211-285f17.1	0.073
mpped2	metallophosphoesterase domain containing 2	0.073
efna5b	ephrin A5b	0.073
mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.073
jak3	Janus kinase 3 (a protein tyrosine kinase, leukocyte)	0.072	Mouse
nphs1l	nephrosis 1, congenital, Finnish type (nephrin)-like	0.072
xrcc5	X-ray repair complementing defective repair in Chinese hamster cells 5	0.072
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.072
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.071
znf711	zinc finger protein 711	0.071
entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.071
akt2	v-akt murine thymoma viral oncogene homolog 2	0.071	Human Mouse Worm Fly
mxi1	max interacting protein	0.071
smad2	MAD homolog 2 (Drosophila)	0.071	Human Zebrafish Mouse
bcl2l1	bcl2-like 1	0.071
sp9	sp9 transcription factor	0.070
cntn1b	contactin 1b	0.070
homez	homeodomain leucine zipper gene	0.070
rab11fip4a	RAB11 family interacting protein 4 (class II) a	0.070
gli3	GLI-Kruppel family member GLI3	0.070
ptpreb	protein tyrosine phosphatase, receptor type, E, b	0.070	Mouse Rat
ndr1	nodal-related 1	0.070
cdh4	cadherin 4, retinal	0.069
aida	axin interaction partner and dorsalization antagonist	0.068
mef2d	myocyte enhancer factor 2d	0.068
k23	k23 gene	0.068
LOC556647	GDNF family receptor alpha-4-like	0.068
zgc:112211	zgc:112211	0.068
meis3	myeloid ecotropic viral integration site 3	0.067	Zebrafish
uxs1	UDP-glucuronic acid decarboxylase 1	0.067
sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.067
zgc:163064	zgc:163064	0.067
fzd7a	frizzled homolog 7a	0.067
sema3ga	semaphorin 3ga	0.067
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.067
elk4	ELK4, ETS-domain protein	0.067
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.066
axin2	axin 2 (conductin, axil)	0.066
col5a3b	collagen type V alpha-3b	0.066
znf148	zinc finger protein 148	0.066
nots	nothepsin	0.066
angpt2	angiopoietin 2	0.066
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.066
lzts2a	leucine zipper, putative tumor suppressor 2a	0.066
angpt1	angiopoietin 1	0.066	Mouse
esr2b	estrogen receptor 2b	0.066	Rat
naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	0.066
acp5b	acid phosphatase 5b, tartrate resistant	0.066
dbh	dopamine beta hydroxylase	0.065
sdc2	syndecan 2	0.065
ptprsa	protein tyrosine phosphatase, receptor type, s, a	0.065
arcn1l	archain 1 like	0.065
atoh8	atonal homolog 8	0.065
ins	preproinsulin	0.065	Mouse
onecutl	one cut domain, family member, like	0.065
zgc:153154	zgc:153154	0.064
sb:cb81	sb:cb81	0.064
git2b	G protein-coupled receptor kinase interactor 2b	0.064
lhx1a	LIM homeobox 1a	0.064
irgq1	immunity-related GTPase family, q1	0.064
h1m	linker histone H1M	0.064
efnb3b	ephrin B3b	0.064	Human Worm
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.063
irx5b	iroquois homeobox protein 5b	0.063
zmpste24	zinc metallopeptidase, STE24 homolog	0.063
vax2	ventral anterior homeobox 2	0.063
tfe3a	transcription factor binding to IGHM enhancer 3a	0.063
fgfrl1a	fibroblast growth factor receptor-like 1a	0.063
hs6st3	heparan sulfate 6-O-sulfotransferase 3	0.063	Fly
htra1a	HtrA serine peptidase 1a	0.063
prkcbb	protein kinase C, beta b	0.063	Rat
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.063	Zebrafish
irbp	interphotoreceptor retinoid-binding protein	0.063
frem1a	Fras1 related extracellular matrix 1a	0.062
nppa	natriuretic peptide precursor A	0.062
si:ch1073-351m12.1	si:ch1073-351m12.1	0.062
gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.062
sdcbp	syndecan binding protein (syntenin)	0.062
st3gal2l	ST3 beta-galactoside alpha-2,3-sialyltransferase 2, like	0.062
ripk2	receptor-interacting serine-threonine kinase 2	0.062
lmbr1l	limb region 1 like	0.062
ier5l	immediate early response 5-like	0.061
skia	nuclear oncoprotein skia	0.061	Human Mouse
ptprb	protein tyrosine phosphatase, receptor type, b	0.061
rps6ka3a	ribosomal protein S6 kinase, polypeptide 3a	0.061
gdf11	growth differentiation factor 11	0.061	Zebrafish
gnat1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.061
napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.061
ahr2	aryl hydrocarbon receptor 2	0.061
lingo1b	leucine rich repeat and Ig domain containing 1b	0.061
grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.061
szl	sizzled	0.061
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.061
tmem88a	transmembrane protein 88 a	0.060
vegfaa	vascular endothelial growth factor Aa	0.060
stc1l	stanniocalcin 1, like	0.060
gng13a	guanine nucleotide binding protein (G protein), gamma 13a	0.060	Zebrafish
oxtl	oxytocin-like	0.060
dlx2a	distal-less homeobox gene 2a	0.060
ntrk2a	neurotrophic tyrosine kinase, receptor, type 2a	0.060
tfr1a	transferrin receptor 1a	0.060
copeb	core promoter element binding protein	0.060
rnd3a	Rho family GTPase 3a	0.060
ext2	exostoses (multiple) 2	0.060
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.059	Zebrafish
eml2	echinoderm microtubule associated protein like 2	0.059
robo2	roundabout homolog 2	0.059
hlxb9lb	homeo box HB9 like b	0.059
map2k4a	mitogen-activated protein kinase kinase 4a	0.059
rassf8b	Ras association (RalGDS/AF-6) domain family 8b	0.059
scinla	scinderin like a	0.059
cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.059
flot2a	flotillin 2a	0.059
pvrl1b	poliovirus receptor-related 1b	0.058
tead3a	TEA domain family member 3 a	0.058
myf5	myogenic factor 5	0.058
bbc3	BCL2 binding component 3	0.058
frem3	Fras1 related extracellular matrix 3	0.058
zic6	zic family member 6	0.058	Fly
cx27.5	connexin 27.5	0.058
barx1	BarH-like homeobox 1	0.058
msi2b	musashi homolog 2b (Drosophila)	0.058
fabp11b	fatty acid binding protein 11b	0.058
tardbp	TAR DNA binding protein	0.057
guk1	guanylate kinase 1	0.057
diaph2	diaphanous homolog 2 (Drosophila)	0.057
tbx4	T-box 4	0.057
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.057
slc16a1	solute carrier family 16 (monocarboxylic acid transporters), member 1	0.057
gng2	guanine nucleotide binding protein (G protein), gamma 2	0.057
grb10a	growth factor receptor-bound protein 10a	0.057	Human Mouse Rat
paf1	paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.057
foxb1.2	forkhead box B1.2	0.057
wwp2	WW domain containing E3 ubiquitin protein ligase 2	0.057
plxnb2a	plexin b2a	0.056
msxd	muscle segment homeobox D	0.056
tph2	tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)	0.056	Worm
jag1a	jagged 1a	0.056	Zebrafish
cntfr	ciliary neurotrophic factor receptor	0.056
epha2	eph receptor A2	0.056	Human Mouse
tfr1b	transferrin receptor 1b	0.056
il8	interleukin 8	0.056
tk1	thymidine kinase 1, soluble	0.056
igf2b	insulin-like growth factor 2b	0.056	Human Mouse
hcst	hematopoietic cell signal transducer	0.055
sbf1	SET binding factor 1	0.055
nr2f1b	nuclear receptor subfamily 2, group F, member 1b	0.055
c1ql4l	complement component 1, q subcomponent-like 4 like	0.055
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.055	Fly
hif1al	hypoxia-inducible factor 1, alpha subunit, like	0.055
crip2	cysteine-rich protein 2	0.055
rasgrp3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	0.055
gadd45bb	growth arrest and DNA-damage-inducible, beta b	0.055
otx1a	orthodenticle homolog 1a	0.055
adra2a	adrenergic, alpha-2A-, receptor	0.054	Human
btbd6a	BTB (POZ) domain containing 6a	0.054
ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.054
dynlrb1	dynein, light chain, roadblock-type 1	0.054
mknk2b	MAP kinase-interacting serine/threonine kinase 2b	0.054
slc25a25a	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a	0.054
adipoql	adiponectin, C1Q and collagen domain containing, like	0.054	Mouse
heyl	hairy/enhancer-of-split related with YRPW motif-like	0.054
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.054	Zebrafish
junbl	jun B proto-oncogene, like	0.054
e2f5	E2F transcription factor 5	0.054
mt2	metallothionein 2	0.054
tfeb	transcription factor EB	0.054
si:rp71-39b20.7	si:rp71-39b20.7	0.054
zgc:110796	zgc:110796	0.054
tgfbr2	transforming growth factor, beta receptor II	0.054	Human Zebrafish Mouse Rat
zgc:55558	zgc:55558	0.054	Worm
meis2.1	myeloid ecotropic viral integration site 2.1	0.053
mlh1	mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)	0.053
rbpms2	RNA binding protein with multiple splicing 2	0.053
igfbp5a	insulin-like growth factor binding protein 5a	0.053	Human Zebrafish Mouse
sept9b	septin 9b	0.053
cpla2	cytosolic phospholipase a2	0.053
notum3	notum 3	0.053
pparg	peroxisome proliferator activated receptor gamma	0.053
rela	v-rel reticuloendotheliosis viral oncogene homolog A	0.053
gngt1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.053	Zebrafish
gnat2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.053
lpp	LIM domain containing preferred translocation partner in lipoma	0.053
csrnp1a	cysteine-serine-rich nuclear protein 1a	0.053
wnt8a	wingless-type MMTV integration site family, member 8a	0.052
zgc:73359	zgc:73359	0.052
adarb1	adenosine deaminase, RNA-specific, B1	0.052
msxb	muscle segment homeobox B	0.052
LOC100003514	protein kinase C alpha type-like	0.052
buc	bucky ball	0.052
rho	rhodopsin	0.052
add3a	adducin 3 (gamma) a	0.052
hspb1	heat shock protein, alpha-crystallin-related, 1	0.052	Human
zgc:136894	zgc:136894	0.052	Mouse
gh1	growth hormone 1	0.052
dock5	dedicator of cytokinesis 5	0.052
notch1b	notch homolog 1b	0.052	Mouse
top2b	topoisomerase (DNA) II beta	0.052
ppp2cb	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	0.052
foxo3a	forkhead box O3A	0.052	Worm Fly
cnppd1	cyclin Pas1/PHO80 domain containing 1	0.051
neurod4	neurogenic differentiation 4	0.051
zgc:56085	zgc:56085	0.051
pitx2	paired-like homeodomain transcription factor 2	0.051
gabbr1a	gamma-aminobutyric acid (GABA) B receptor, 1a	0.051
cry3	cryptochrome 3	0.051
clptm1	cleft lip and palate associated transmembrane protein 1	0.051
eng2b	engrailed 2b	0.051
thbs3a	thrombospondin 3a	0.051
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.051
acvr2b	activin receptor IIb	0.051	Human
krt18	keratin 18	0.051
edar	ectodysplasin A receptor	0.050
fzd9b	frizzled homolog 9b	0.050
sh3gl1b	SH3-domain GRB2-like 1b	0.050
rxraa	retinoid X receptor, alpha a	0.050
ncl1	nicalin	0.050
pglyrp2	peptidoglycan recognition protein 2	0.050
tnfa	tumor necrosis factor a (TNF superfamily, member 2)	0.050
zdhhc8b	zinc finger, DHHC-type containing 8b	0.050
pak2b	p21 (CDKN1A)-activated kinase 2b	0.050
cpb1	carboxypeptidase B1 (tissue)	0.050
capn1a	calpain 1, (mu/I) large subunit a	0.050
il6r	interleukin 6 receptor	0.050
olig4	oligodendrocyte transcription factor 4	0.049
musk	muscle, skeletal, receptor tyrosine kinase	0.049
wnt3	wingless-type MMTV integration site family, member 3	0.049	Zebrafish
jak1	Janus kinase 1	0.049	Mouse
slc12a10.2	solute carrier family 12 (sodium/potassium/chloride transporters), member 10.2	0.049
ube2nb	ubiquitin-conjugating enzyme E2Nb	0.049
zgc:56010	zgc:56010	0.049
zgc:92014	zgc:92014	0.049
zgc:63840	zgc:63840	0.049
nhsl1b	NHS-like 1b	0.049
ehd1	EH-domain containing 1	0.049
pigu	phosphatidylinositol glycan anchor biosynthesis, class U	0.049
rfng	radical fringe homolog (Drosophila)	0.049
cry1a	cryptochrome 1a	0.049
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.048
pknox2	pbx/knotted 1 homeobox 2	0.048	Zebrafish
st8sia6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	0.048
rlbp1a	retinaldehyde binding protein 1a	0.048