IMP
Process View
cofactor metabolic process
The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cofactor metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| alas2 | aminolevulinate, delta-, synthetase 2 | 0.351 | ||
| epb41 | erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) | 0.343 | ||
| tfr1a | transferrin receptor 1a | 0.271 | ||
| uros | uroporphyrinogen III synthase | 0.247 | Mouse | |
| slc4a2b | solute carrier family 4, anion exchanger, member 2b | 0.235 | ||
| urod | uroporphyrinogen decarboxylase | 0.210 | ||
| brp44 | brain protein 44 | 0.200 | ||
| aldh7a1 | aldehyde dehydrogenase 7 family, member A1 | 0.197 | ||
| prdx2 | peroxiredoxin 2 | 0.136 | ||
| aco1 | aconitase 1, soluble | 0.132 | ||
| chchd10 | coiled-coil-helix-coiled-coil-helix domain containing 10 | 0.122 | ||
| pawrl | PRKC, apoptosis, WT1, regulator like | 0.087 | ||
| fech | ferrochelatase | 0.077 | Mouse | |
| mvp | major vault protein | 0.073 | ||
| slc4a1a | solute carrier family 4, anion exchanger, member 1a | 0.067 | ||
| lap3 | leucine aminopeptidase 3 | 0.066 | ||
| pgd | phosphogluconate hydrogenase | 0.061 | Human | |
| selt1a | selenoprotein T, 1a | 0.049 | ||
| zgc:64042 | zgc:64042 | 0.047 | ||
| klfd | Kruppel-like factor d | 0.046 | ||
| gbgt1l4 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 | 0.046 | ||
| glrx | glutaredoxin (thioltransferase) | 0.042 | ||
| ucp2 | uncoupling protein 2 | 0.039 | ||
| cd63 | Cd63 antigen | 0.037 | ||
| hbae1 | hemoglobin alpha embryonic-1 | 0.035 | ||
| slc12a3 | solute carrier family 12 (sodium/chloride transporters), member 3 | 0.035 | ||
| blvrb | biliverdin reductase B (flavin reductase (NADPH)) | 0.034 | ||
| pccb | propionyl Coenzyme A carboxylase, beta polypeptide | 0.034 | ||
| got2b | glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2) | 0.034 | ||
| ddt | D-dopachrome tautomerase | 0.033 | ||
| echdc2 | enoyl CoA hydratase domain containing 2 | 0.031 | ||
| sod2 | superoxide dismutase 2, mitochondrial | 0.031 | ||
| tyms | thymidylate synthase | 0.030 | ||
| cldn7b | claudin 7b | 0.030 | ||
| capn2b | calpain 2, (m/II) large subunit b | 0.030 | ||
| hspd1 | heat shock 60kD protein 1 (chaperonin) | 0.029 | ||
| gata1a | GATA binding protein 1a | 0.029 | ||
| dera | 2-deoxyribose-5-phosphate aldolase homolog (C. elegans) | 0.028 | ||
| sdhb | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 0.028 | ||
| aco2 | aconitase 2, mitochondrial | 0.027 | ||
| cbr1l | carbonyl reductase 1-like | 0.026 | ||
| zgc:101723 | zgc:101723 | 0.026 | ||
| hadh | hydroxyacyl-Coenzyme A dehydrogenase | 0.026 | ||
| mthfd1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) | 0.025 | ||
| cldnf | claudin f | 0.025 | ||
| iba57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) | 0.025 | ||
| idh3a | isocitrate dehydrogenase 3 (NAD+) alpha | 0.024 | Rat | |
| ppox | protoporphyrinogen oxidase | 0.024 | ||
| tspo | translocator protein | 0.024 | ||
| impdh2 | IMP (inosine monophosphate) dehydrogenase 2 | 0.024 | ||
| acvr2a | activin receptor IIa | 0.023 | ||
| mre11a | meiotic recombination 11 homolog A (S. cerevisiae) | 0.023 | ||
| glrx5 | glutaredoxin 5 homolog (S. cerevisiae) | 0.022 | ||
| ndufa8 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8 | 0.022 | ||
| sucla2 | succinate-CoA ligase, ADP-forming, beta subunit | 0.022 | ||
| zgc:92745 | zgc:92745 | 0.022 | ||
| ctage5 | CTAGE family, member 5 | 0.022 | ||
| si:ch211-160j6.2 | si:ch211-160j6.2 | 0.021 | ||
| arrdc1a | arrestin domain containing 1a | 0.021 | ||
| adka | adenosine kinase a | 0.021 | ||
| ctsz | cathepsin Z | 0.021 | ||
| prdx3 | peroxiredoxin 3 | 0.021 | ||
| zgc:73293 | zgc:73293 | 0.021 | ||
| ctsd | cathepsin D | 0.020 | ||
| ehhadh | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 0.020 | ||
| tufm | Tu translation elongation factor, mitochondrial | 0.020 | ||
| glulb | glutamate-ammonia ligase (glutamine synthase) b | 0.020 | ||
| hbbe3 | hemoglobin beta embryonic-3 | 0.020 | ||
| bpnt1 | bisphosphate nucleotidase 1 | 0.019 | ||
| bckdhb | branched chain ketoacid dehydrogenase E1, beta polypeptide | 0.019 | ||
| bdh2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.019 | ||
| ivns1abpa | influenza virus NS1A binding protein a | 0.018 | ||
| ndufb6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 | 0.018 | ||
| zgc:162943 | zgc:162943 | 0.018 | ||
| cox17 | COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.017 | ||
| atp7a | ATPase, Cu++ transporting, alpha polypeptide | 0.017 | ||
| zgc:55813 | zgc:55813 | 0.017 | ||
| nccrp1 | nonspecific cytotoxic cell receptor protein 1 | 0.017 | ||
| ctsl1a | cathepsin L, 1 a | 0.017 | ||
| zgc:92903 | zgc:92903 | 0.017 | ||
| zgc:86841 | zgc:86841 | 0.016 | ||
| alad | aminolevulinate dehydratase | 0.016 | ||
| zgc:73273 | zgc:73273 | 0.016 | ||
| prkab1b | protein kinase, AMP-activated, beta 1 non-catalytic subunit, b | 0.016 | ||
| phyhd1 | phytanoyl-CoA dioxygenase domain containing 1 | 0.016 | ||
| serpinb1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.016 | ||
| hmbsb | hydroxymethylbilane synthase, b | 0.015 | ||
| dhdhl | dihydrodiol dehydrogenase (dimeric), like | 0.015 | ||
| zgc:198195 | zgc:198195 | 0.015 | ||
| cyc1 | cytochrome c-1 | 0.015 | ||
| dldh | dihydrolipoamide dehydrogenase | 0.015 | ||
| zgc:101724 | zgc:101724 | 0.015 | ||
| slc11a2 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 0.015 | ||
| hbbe2 | hemoglobin beta embryonic-2 | 0.015 | ||
| tmem184a | transmembrane protein 184a | 0.015 | ||
| ireb2 | iron-responsive element binding protein 2 | 0.015 | Mouse | |
| upb1 | ureidopropionase, beta | 0.015 | ||
| sccpdhb | saccharopine dehydrogenase b | 0.015 | ||
| zgc:73311 | zgc:73311 | 0.014 | ||
| sdha | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.014 | ||
| ezr | ezrin | 0.014 | ||
| st14a | suppression of tumorigenicity 14 (colon carcinoma) a | 0.014 | ||
| cpa2 | carboxypeptidase A2 (pancreatic) | 0.014 | ||
| acy3.2 | aspartoacylase (aminocyclase) 3.2 | 0.014 | ||
| cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.014 | ||
| atp1b1a | ATPase, Na+/K+ transporting, beta 1a polypeptide | 0.014 | ||
| sepx1a | selenoprotein X, 1a | 0.014 | ||
| arfip2b | ADP-ribosylation factor interacting protein 2b | 0.014 | ||
| tmem14c | transmembrane protein 14C | 0.014 | ||
| cldnh | claudin h | 0.013 | ||
| ogdh | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.013 | ||
| zgc:77655 | zgc:77655 | 0.013 | ||
| tkt | transketolase | 0.013 | ||
| aldh4a1 | aldehyde dehydrogenase 4 family, member A1 | 0.013 | ||
| sult3st1 | sulfotransferase family 3, cytosolic sulfotransferase 1 | 0.013 | ||
| tjp2b | tight junction protein 2b (zona occludens 2) | 0.013 | ||
| capns1a | calpain, small subunit 1 a | 0.013 | ||
| c20orf11 | c20orf11 homolog (H. sapiens) | 0.013 | ||
| zgc:92061 | zgc:92061 | 0.013 | ||
| zgc:110010 | zgc:110010 | 0.013 | ||
| gnpda1 | glucosamine-6-phosphate deaminase 1 | 0.013 | ||
| zgc:56005 | zgc:56005 | 0.013 | ||
| hdr | hematopoietic death receptor | 0.013 | ||
| txnrd1 | thioredoxin reductase 1 | 0.013 | ||
| dab2 | disabled homolog 2 (Drosophila) | 0.013 | ||
| bbs2 | Bardet-Biedl syndrome 2 | 0.013 | ||
| fdx1 | ferredoxin 1 | 0.013 | ||
| chp | calcium binding protein P22 | 0.012 | ||
| pdcd8 | programmed cell death 8 (apoptosis-inducing factor) | 0.012 | ||
| atp6v1ba | ATPase, H+ transporting, lysosomal, V1 subunit B, member a | 0.012 | ||
| ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.012 | ||
| pepd | peptidase D | 0.012 | ||
| elovl5 | ELOVL family member 5, elongation of long chain fatty acids (yeast) | 0.012 | ||
| zgc:158605 | zgc:158605 | 0.012 | ||
| hig1 | hypoxia induced gene 1 | 0.012 | ||
| tsc1a | tuberous sclerosis 1a | 0.012 | ||
| gpt2l | glutamic pyruvate transaminase (alanine aminotransferase) 2, like | 0.012 | ||
| oclna | occludin a | 0.012 | Rat | |
| rps6ka3a | ribosomal protein S6 kinase, polypeptide 3a | 0.012 | ||
| mapk4 | mitogen-activated protein kinase 4 | 0.012 | ||
| nsdhl | NAD(P) dependent steroid dehydrogenase-like | 0.012 | ||
| slc25a39 | solute carrier family 25, member 39 | 0.012 | ||
| mesp2 | mesoderm posterior 2 homolog (mouse) | 0.012 | ||
| uqcrc1 | ubiquinol-cytochrome c reductase core protein I | 0.012 | ||
| zgc:112992 | zgc:112992 | 0.012 | ||
| suclg1 | succinate-CoA ligase, GDP-forming, alpha subunit | 0.012 | ||
| si:dkey-13i19.8 | si:dkey-13i19.8 | 0.012 | ||
| adam23a | a disintegrin and metallopeptidase domain 23a | 0.012 | ||
| esrp2 | epithelial splicing regulatory protein 2 | 0.011 | ||
| si:ch211-233e16.1 | si:ch211-233e16.1 | 0.011 | ||
| slc9a3r1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.011 | ||
| sepp1b | selenoprotein P, plasma, 1b | 0.011 | ||
| mdh1a | malate dehydrogenase 1a, NAD (soluble) | 0.011 | ||
| zgc:111961 | zgc:111961 | 0.011 | ||
| ache | acetylcholinesterase | 0.011 | ||
| slc3a2 | solute carrier family 3, member 2 | 0.011 | ||
| tm9sf1 | transmembrane 9 superfamily member 1 | 0.011 | ||
| zgc:92027 | zgc:92027 | 0.011 | ||
| zff9 | zinc finger protein 9 | 0.011 | ||
| mrpl28 | mitochondrial ribosomal protein L28 | 0.011 | ||
| nadl1.2 | neural adhesion molecule L1.2 | 0.011 | ||
| shmt2 | serine hydroxymethyltransferase 2 (mitochondrial) | 0.011 | ||
| snx9 | sorting nexin 9 | 0.011 | ||
| krit1 | KRIT1, ankyrin repeat containing | 0.011 | ||
| bad | BCL2-antagonist of cell death | 0.011 | ||
| ccne | cyclin E | 0.011 | ||
| sdr16c5b | short chain dehydrogenase/reductase family 16C, member 5b | 0.011 | ||
| gpx1a | glutathione peroxidase 1a | 0.011 | ||
| cpvl | carboxypeptidase, vitellogenic-like | 0.011 | ||
| gspt1 | G1 to S phase transition 1 | 0.011 | ||
| zgc:112056 | zgc:112056 | 0.011 | ||
| si:ch211-217g15.2 | si:ch211-217g15.2 | 0.011 | ||
| aldoaa | aldolase a, fructose-bisphosphate, a | 0.011 | ||
| nit1 | nitrilase 1 | 0.011 | ||
| sirt5 | sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) | 0.010 | ||
| ttc8 | tetratricopeptide repeat domain 8 | 0.010 | ||
| si:dkey-97i18.2 | si:dkey-97i18.2 | 0.010 | ||
| zgc:162396 | zgc:162396 | 0.010 | ||
| si:ch211-1n9.7 | si:ch211-1n9.7 | 0.010 | ||
| zgc:77775 | zgc:77775 | 0.010 | ||
| myo5b | myosin VB | 0.010 | ||
| march5l | membrane-associated ring finger (C3HC4) 5, like | 0.010 | ||
| wu:fc51d09 | wu:fc51d09 | 0.010 | ||
| etfa | electron-transfer-flavoprotein, alpha polypeptide | 0.010 | ||
| sbno1 | strawberry notch homolog 1 (Drosophila) | 0.010 | ||
| pcbd1 | 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) | 0.010 | ||
| im:7146326 | im:7146326 | 0.010 | ||
| polr3gla | polymerase (RNA) III (DNA directed) polypeptide G like a | 0.010 | ||
| vgll4l | vestigial like 4 like | 0.010 | ||
| gpia | glucose phosphate isomerase a | 0.010 |