IMP: Integrative Multi-species Prediction

Danio rerio

2 genes annotated in zebrafish

proteasome mediated ubiquitin dependent protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "proteasome mediated ubiquitin dependent protein catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "proteasome mediated ubiquitin dependent protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
psmb1	proteasome (prosome, macropain) subunit, beta type, 1	0.959
psma8	proteasome (prosome, macropain) subunit, alpha type, 8	0.905	Yeast
psma6a	proteasome (prosome, macropain) subunit, alpha type, 6a	0.889	Yeast
psmd6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.873
psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.865
psmb3	proteasome (prosome, macropain) subunit, beta type, 3	0.782	Yeast
ccnb1	cyclin B1	0.755
zgc:92775	zgc:92775	0.731
psmb2	proteasome (prosome, macropain) subunit, beta type, 2	0.704	Yeast
psma4	proteasome (prosome, macropain) subunit, alpha type, 4	0.687	Yeast
psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.673
psmb4	proteasome (prosome, macropain) subunit, beta type, 4	0.664	Yeast
ccna2	cyclin A2	0.663
psmb7	proteasome (prosome, macropain) subunit, beta type, 7	0.662	Yeast
psmc6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.647
kif23	kinesin family member 23	0.615
psmc1b	proteasome (prosome, macropain) 26S subunit, ATPase, 1b	0.580
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.537
plk1	polo-like kinase 1 (Drosophila)	0.527	Human
btg2	B-cell translocation gene 2	0.506
vcp	valosin containing protein	0.482	Human Yeast Rat Worm
psmc4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.481
max	myc-associated factor X	0.465
psmc5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.461	Human Yeast Worm
hspa5	heat shock protein 5	0.455	Yeast
psmc3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.410
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.399
psma1	proteasome (prosome, macropain) subunit, alpha type, 1	0.393
usp5	ubiquitin specific protease 5	0.373	Human Fly
ck2b	casein kinase 2 beta	0.359
slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.356
sec24c	SEC24 family, member C (S. cerevisiae)	0.341
aurkb	aurora kinase B	0.334
zgc:86903	zgc:86903	0.333
psmb5	proteasome (prosome, macropain) subunit, beta type, 5	0.332
bnip3lb	BCL2/adenovirus E1B interacting protein 3-like b	0.313
kpna4	karyopherin alpha 4 (importin alpha 3)	0.305
zgc:56304	zgc:56304	0.305
psmc1a	proteasome (prosome, macropain) 26S subunit, ATPase, 1a	0.305
baxa	bcl2-associated X protein, a	0.286
psma6b	proteasome (prosome, macropain) subunit, alpha type, 6b	0.283	Yeast
psmd1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.282
prpf40a	PRP40 pre-mRNA processing factor 40 homolog A (yeast)	0.270
ciapin1	cytokine induced apoptosis inhibitor 1	0.268
chuk	conserved helix-loop-helix ubiquitous kinase	0.267
sirt1	sirtuin (silent mating type information regulation 2 homolog) 1	0.265
adrm1b	adhesion regulating molecule 1b	0.264
rtkn2	rhotekin 2	0.261
psmd13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.258
zgc:56596	zgc:56596	0.255
psma2	proteasome (prosome, macropain) subunit, alpha type, 2	0.250	Yeast
hspa4b	heat shock protein 4b	0.248
zgc:56200	zgc:56200	0.248
fxr2	fragile X mental retardation, autosomal homolog 2	0.245
ywhaba	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a	0.240
zgc:110116	zgc:110116	0.233
dynlrb1	dynein, light chain, roadblock-type 1	0.229
psmd4b	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4b	0.229
zgc:111944	zgc:111944	0.228
cul1b	cullin 1b	0.225	Human Mouse
myf5	myogenic factor 5	0.223
acvr1b	activin A receptor, type IB	0.221
cdc20	cell division cycle 20 homolog	0.221	Human Yeast Worm Fly
rab1a	RAB1A, member RAS oncogene family	0.217
rbl1	retinoblastoma-like 1 (p107)	0.214
smad9	MAD homolog 9 (Drosophila)	0.213
gna13a	guanine nucleotide binding protein (G protein), alpha 13a	0.211
senp3a	SUMO1/sentrin/SMT3 specific peptidase 3a	0.208
plekha3	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3	0.205
cnot6	CCR4-NOT transcription complex, subunit 6	0.204
tfpi2	tissue factor pathway inhibitor 2	0.203
dnajc3	DnaJ (Hsp40) homolog, subfamily C, member 3	0.202
brd3a	bromodomain containing 3a	0.198
mapkapk2a	mitogen-activated protein kinase-activated protein kinase 2a	0.197
hyou1	hypoxia up-regulated 1	0.197
shfm1	split hand/foot malformation (ectrodactyly) type 1	0.196
glulb	glutamate-ammonia ligase (glutamine synthase) b	0.195
gtf2a1	general transcription factor IIA, 1	0.195
ccnb2	cyclin B2	0.193
ccne	cyclin E	0.186	Fly
psmb11	proteasome (prosome, macropain) subunit, beta type, 11	0.184
tia1l	cytotoxic granule-associated RNA binding protein 1, like	0.184
cul3a	cullin 3a	0.183	Human Mouse
tia1	cytotoxic granule-associated RNA binding protein 1	0.183
psmd11a	proteasome (prosome, macropain) 216S subunit, non-ATPase, 11a	0.182
hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.180
flii	flightless I homolog (Drosophila)	0.176
smad2	MAD homolog 2 (Drosophila)	0.175
dnaja2l	DnaJ (Hsp40) homolog, subfamily A, member 2, like	0.174
xrn1	5'-3' exoribonuclease 1	0.173
pppde1	PPPDE peptidase domain containing 1	0.173
csnk1g2a	casein kinase 1, gamma 2a	0.173
ube2g2	ubiquitin-conjugating enzyme E2G 2	0.171
glrx3	glutaredoxin 3	0.170
setd7	SET domain containing (lysine methyltransferase) 7	0.170
zfand2a	zinc finger, AN1-type domain 2A	0.169
exoc3	exocyst complex component 3	0.169
eif4h	eukaryotic translation initiation factor 4h	0.169
bsdc1	BSD domain containing 1	0.168
gsc	goosecoid	0.167
zgc:123326	zgc:123326	0.166
atxn2l	ataxin 2-like	0.166
syvn1	synovial apoptosis inhibitor 1, synoviolin	0.165	Human
fzd7b	frizzled homolog 7b	0.164
gdi2	GDP dissociation inhibitor 2	0.162
rnf10	ring finger protein 10	0.162
cdk8	cyclin-dependent kinase 8	0.161
hist2h2l	histone 2, H2, like	0.160
akirin2	akirin 2	0.160
csnk1db	casein kinase 1, delta b	0.159	Mouse Fly
ube2i2	ubiquitin-conjugating enzyme E2I2	0.159	Rat
sec61al1	Sec61 alpha like 1	0.158
kpna2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.155
rab11ba	RAB11B, member RAS oncogene family, a	0.155
capn2b	calpain 2, (m/II) large subunit b	0.153
cnpy1	canopy1	0.152
herpud1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.151
cct5	chaperonin containing TCP1, subunit 5 (epsilon)	0.148
zgc:158603	zgc:158603	0.148
faf2	Fas associated factor family member 2	0.147
si:ch73-9j13.1	si:ch73-9j13.1	0.147
gro2	groucho 2	0.146
ythdf3	YTH domain family 3	0.146
racgap1	Rac GTPase-activating protein 1	0.146
zgc:103670	zgc:103670	0.146
kdm5c	lysine (K)-specific demethylase 5C	0.145
cand1	cullin-associated and neddylation-dissociated 1	0.145
mxa	myxovirus (influenza) resistance A	0.145
ythdf1	YTH domain family, member 1	0.144
psmb8	proteasome (prosome, macropain) subunit, beta type, 8	0.144
wdr33	WD repeat domain 33	0.143
cdca8	cell division cycle associated 8	0.142
rqcd1	RCD1 required for cell differentiation1 homolog (S. pombe)	0.140
hoxb1b	homeo box B1b	0.140
eif5a2	eukaryotic translation initiation factor 5A2	0.140
zgc:101121	zgc:101121	0.139
ube2d2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.139
zgc:153910	zgc:153910	0.138
si:ch211-69g19.2	si:ch211-69g19.2	0.136
smek1	SMEK homolog 1, suppressor of mek1 (Dictyostelium)	0.134
eif3s10	eukaryotic translation initiation factor 3, subunit 10 (theta)	0.134
tp53	tumor protein p53	0.133
drap1	DR1-associated protein 1 (negative cofactor 2 alpha)	0.132
sept7b	septin 7b	0.132
si:rp71-45k5.4	si:rp71-45k5.4	0.132
tra2a	transformer-2 alpha	0.131
zgc:55683	zgc:55683	0.131
klhdc10	kelch domain containing 10	0.131
vps52	vacuolar protein sorting 52 (yeast)	0.131
zgc:101724	zgc:101724	0.130
tpt1	tumor protein, translationally-controlled 1	0.126
dusp1	dual specificity phosphatase 1	0.124
ddx42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42	0.123
npc1	Niemann-Pick disease, type C1	0.123
fzd7a	frizzled homolog 7a	0.122
psmd2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.122
arntl1b	aryl hydrocarbon receptor nuclear translocator-like 1b	0.121	Mouse
rplp0	ribosomal protein, large, P0	0.121
mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.120
stard3	START domain containing 3	0.120
xbp1	X-box binding protein 1	0.120
prkci	protein kinase C, iota	0.120
ncor1	nuclear receptor co-repressor 1	0.119
tbc1d23	TBC1 domain family, member 23	0.119
sec23a	Sec23 homolog A (S. cerevisiae)	0.119
whsc2	Wolf-Hirschhorn syndrome candidate 2	0.118
pcdh18b	protocadherin 18b	0.118
hspa8	heat shock protein 8	0.117
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.115
zgc:162965	zgc:162965	0.115
gps1	G protein pathway suppressor 1	0.115
lrmp	lymphoid-restricted membrane protein	0.114
papolg	poly(A) polymerase gamma	0.113
aup1	ancient ubiquitous protein 1	0.111
orc1	origin recognition complex, subunit 1	0.110
birc5a	baculoviral IAP repeat-containing 5a	0.110
zgc:56376	zgc:56376	0.110
nedd8	neural precursor cell expressed, developmentally down-regulated 8	0.110
entpd4	ectonucleoside triphosphate diphosphohydrolase 4	0.110
ihha	Indian hedgehog homolog a	0.109
galcb	galactosylceramidase b	0.109
bmp8a	bone morphogenetic protein 8a	0.109
eif4enif1	eukaryotic translation initiation factor 4E nuclear import factor 1	0.108
tnpo3	transportin 3	0.108
rae1	RAE1 RNA export 1 homolog (S. pombe)	0.108
sumo3a	SMT3 suppressor of mif two 3 homolog 3a	0.108
cry4	cryptochrome 4	0.108
gnaia	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a	0.108
snrnp27	small nuclear ribonucleoprotein 27 (U4/U6.U5)	0.108
tollip	toll interacting protein	0.107
si:ch211-197n10.2	si:ch211-197n10.2	0.107
psmd11b	proteasome (prosome, macropain) 216S subunit, non-ATPase, 11b	0.107
nup93	nucleoporin 93	0.106
cops4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.106	Fly
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.105
copg2	coatomer protein complex, subunit gamma 2	0.105
smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.105
arglu1a	arginine and glutamate rich 1a	0.104
stat1b	signal transducer and activator of transcription 1b	0.104
tacc3	transforming, acidic coiled-coil containing protein 3	0.104
ctnnb1	catenin (cadherin-associated protein), beta 1	0.103
arl8ba	ADP-ribosylation factor-like 8Ba	0.103
runx2a	runt-related transcription factor 2a	0.103
cdc37l1	CDC37 cell division cycle 37 homolog (S. cerevisiae)-like 1	0.102
zgc:77817	zgc:77817	0.102
rdbp	RD RNA binding protein	0.102
phf10	PHD finger protein 10	0.101
srsf11	serine/arginine-rich splicing factor 11	0.100
bag6	BCL2-associated athanogene 6	0.100
arf2	ADP-ribosylation factor 2	0.100
snrpc	small nuclear ribonucleoprotein polypeptide C	0.100
slc39a7	solute carrier family 39 (zinc transporter), member 7	0.100
dharma	dharma	0.099
pkp2	plakophilin 2	0.099
sub1	SUB1 homolog (S. cerevisiae)	0.099
cdt1	chromatin licensing and DNA replication factor 1	0.098
pbx2	pre-B-cell leukemia transcription factor 2	0.098
gstp1	glutathione S-transferase pi	0.098
rcc2	regulator of chromosome condensation 2	0.098
eif1axb	eukaryotic translation initiation factor 1A, X-linked, b	0.098
tbx6	T-box gene 6	0.097
tax1bp1b	Tax1 (human T-cell leukemia virus type I) binding protein 1b	0.097
hirip5	HIRA interacting protein 5	0.097
im:7142942	im:7142942	0.096
foxa2	forkhead box A2	0.096
tfam	transcription factor A, mitochondrial	0.096
gle1	GLE1 RNA export mediator homolog (yeast)	0.096
atp1b3b	ATPase, Na+/K+ transporting, beta 3b polypeptide	0.096
cdc42	cell division cycle 42	0.095
yipf5	Yip1 domain family, member 5	0.095
map2k4b	mitogen-activated protein kinase kinase 4b	0.094
wnt4a	wingless-type MMTV integration site family, member 4a	0.094
prkrir	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	0.094
rem2	RAS (RAD and GEM)-like GTP binding 2	0.093
pald	paladin	0.093
pknox1.1	pbx/knotted 1 homeobox 1.1	0.093
psmb10	proteasome (prosome, macropain) subunit, beta type, 10	0.092
si:ch211-244o22.2	si:ch211-244o22.2	0.092
rsrc2	arginine/serine-rich coiled-coil 2	0.092
golga5	golgi autoantigen, golgin subfamily a, 5	0.091
ef1a	elongation factor 1-alpha	0.091
zgc:103652	zgc:103652	0.091
fbxw11b	F-box and WD-40 domain protein 11b	0.091	Human Mouse
mga	MAX gene associated	0.090
pdlim4	PDZ and LIM domain 4	0.090
elof1	elongation factor 1 homolog (S. cerevisiae)	0.090
srp54	signal recognition particle 54	0.090
cul2	cullin 2	0.090	Worm
rnf40	ring finger protein 40	0.089
yy1a	YY1 transcription factor a	0.089
sass6	spindle assembly 6 homolog (C. elegans)	0.089
zgc:101577	zgc:101577	0.089
fbxw11a	F-box and WD-40 domain protein 11a	0.089	Human Mouse
spast	spastin	0.089
mylipa	myosin regulatory light chain interacting protein a	0.089
dnajb11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.088
copa	coatomer protein complex, subunit alpha	0.088
rbm19	RNA binding motif protein 19	0.088
vps39	vacuolar protein sorting 39 homolog (S. cerevisiae)	0.088
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.088	Human
arpp19a	cAMP-regulated phosphoprotein 19a	0.088
tram1	translocating chain-associating membrane protein 1	0.088
crsp7	cofactor required for Sp1 transcriptional activation, subunit 7	0.087
zgc:55512	zgc:55512	0.087	Yeast Fly
h2afvl	H2A histone family, member V, like	0.087
cse1l	chromosome segregation 1-like (S. cerevisiae)	0.087
dtl	denticleless homolog (Drosophila)	0.087
psmb6	proteasome (prosome, macropain) subunit, beta type, 6	0.087	Yeast
psme1	proteasome activator subunit 1	0.087
nasp	nuclear autoantigenic sperm protein (histone-binding)	0.087
rbmx	RNA binding motif protein, X-linked	0.086
zmpste24	zinc metallopeptidase, STE24 homolog	0.086
wwp1	WW domain containing E3 ubiquitin protein ligase 1	0.086
hspg2	heparan sulfate proteoglycan 2	0.086
slc8a4b	solute carrier family 8 (sodium/calcium exchanger), member 4b	0.086
micall2a	mical-like 2a	0.086
ip6k2	inositol hexaphosphate kinase 2	0.085
cnot8	CCR4-NOT transcription complex, subunit 8	0.085
glmna	glomulin, FKBP associated protein a	0.085
morc2	MORC family CW-type zinc finger 2	0.085
tmem199	transmembrane protein 199	0.085
snx27	sorting nexin family member 27	0.084
prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.084
lancl1	LanC antibiotic synthetase component C-like 1 (bacterial)	0.084
syap1	synapse associated protein 1	0.084
b3gat3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) and beta3-glucuronyltransferase	0.084
uba1	ubiquitin-like modifier activating enzyme 1	0.084
ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.084
ifi35	interferon-induced protein 35	0.083
jhdm1da	jumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae)	0.083
psmb9a	proteasome (prosome, macropain) subunit, beta type, 9a	0.083	Yeast
myst2	MYST histone acetyltransferase 2	0.083
tfg	trk-fused gene	0.083
rabgef1	RAB guanine nucleotide exchange factor (GEF) 1	0.083
inhbb	inhibin, beta B	0.083
mmp14b	matrix metalloproteinase 14b (membrane-inserted)	0.083
g2e3	G2/M-phase specific E3 ubiquitin ligase	0.083
bactin2	bactin2	0.082
axin1	axin 1	0.082	Mouse
hn1l	hematological and neurological expressed 1-like	0.082
si:dkeyp-50f5.1	si:dkeyp-50f5.1	0.082
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.082
piga	phosphatidylinositol glycan anchor biosynthesis, class A	0.081
serpinb1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.081
smad5	MAD homolog 5 (Drosophila)	0.081
fcho2	FCH domain only 2	0.081
ck2a2a	casein kinase 2 alpha 2a	0.081
ppm1d	protein phosphatase 1D magnesium-dependent, delta isoform	0.081
acbd3	acyl-Coenzyme A binding domain containing 3	0.081
tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.080
nploc4	nuclear protein localization 4 homolog (S. cerevisiae)	0.080	Worm
zgc:64114	zgc:64114	0.080
lin52	lin-52 homolog (C. elegans)	0.080
pdgfb	platelet derived growth factor, B polypeptide	0.079
si:ch211-51m24.3	si:ch211-51m24.3	0.079
lass5	LAG1 homolog, ceramide synthase 5 (S. cerevisiae)	0.079
ppp2cb	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	0.079	Mouse
eif3hb	eukaryotic translation initiation factor 3, subunit H, b	0.079
smu1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	0.079
fbxl14a	F-box and leucine-rich repeat protein 14a	0.079
ccnt2a	cyclin T2a	0.079
tsc22d2	TSC22 domain family 2 and TSC22 domain family, member 2	0.078
nexn	nexilin (F actin binding protein)	0.078
zgc:103671	zgc:103671	0.078
plk3	polo-like kinase 3 (Drosophila)	0.078	Human
ran	ras-related nuclear protein	0.078
zgc:56706	zgc:56706	0.078
ap1g1	adaptor-related protein complex 1, gamma 1 subunit	0.077
bc2	putative breast adenocarcinoma marker	0.077
shcbp1	SHC SH2-domain binding protein 1	0.077
pgrmc2	progesterone receptor membrane component 2	0.077
hectd3	HECT domain containing 3	0.077
zgc:91931	zgc:91931	0.077
zgc:55448	zgc:55448	0.077
zgc:92139	zgc:92139	0.076
fbxw2	F-box and WD repeat domain containing 2	0.076
hnrpkl	heterogeneous nuclear ribonucleoprotein K, like	0.076
srsf1a	serine/arginine-rich splicing factor 1a	0.076
smndc1	survival motor neuron domain containing 1	0.075
lonp2	lon peptidase 2, peroxisomal	0.075
cd74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.075
rab11a	RAB11a, member RAS oncogene family	0.075
rlf	rearranged L-myc fusion	0.075
ved	ventrally expressed dharma/bozozok antagonist	0.075
pik3r4	phosphoinositide-3-kinase, regulatory subunit 4	0.074
blmh	bleomycin hydrolase	0.074
naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	0.074
smc4	structural maintenance of chromosomes 4	0.074
kcmf1	potassium channel modulatory factor 1	0.074
lef1	lymphocyte enhancer binding factor 1	0.074
nudc	nuclear distribution gene C homolog	0.073
znf207b	zinc finger protein 207, b	0.073	Human
zgc:55886	zgc:55886	0.073
zfand5a	zinc finger, AN1-type domain 5a	0.073
irf9	interferon regulatory factor 9	0.073
lsm8	LSM8 homolog, U6 small nuclear RNA associated	0.073
rpa2	replication protein A2	0.072
rp42-pen	rp42 homolog (pending) and rp42 homolog	0.072
pitpnb	phosphotidylinositol transfer protein, beta	0.072
plk2b	polo-like kinase 2b (Drosophila)	0.072
sufu	suppressor of fused homolog (Drosophila)	0.072
prdx5	peroxiredoxin 5	0.072
zgc:55870	zgc:55870	0.072
tbcb	tubulin folding cofactor B	0.072
robo3	roundabout homolog 3	0.072
psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.071
supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	0.071
srd5a3	steroid 5 alpha-reductase 3	0.071
pop7	processing of precursor 7, ribonuclease P family	0.071
puf60a	poly-U binding splicing factor a	0.071
vps26bl	vacuolar protein sorting 26 homolog B, like	0.071
sas	sarcoma amplified sequence	0.071
dctn5	dynactin 5	0.071
hoxd13a	homeo box D13a	0.071
zgc:55573	zgc:55573	0.071
nup50	nucleoporin 50	0.071
ndr1	nodal-related 1	0.071
sigmar1	sigma non-opioid intracellular receptor 1	0.070
cdc42se1	CDC42 small effector 1	0.070
nipa2	non imprinted in Prader-Willi/Angelman syndrome 2 (human)	0.070
copb1	coatomer protein complex, subunit beta 1	0.070
zgc:77456	zgc:77456	0.070
slc35b2	solute carrier family 35, member B2	0.070
tsc1	tuberous sclerosis 1	0.070
akirin1	akirin 1	0.069
lsm7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.069
lysmd3	LysM, putative peptidoglycan-binding, domain containing 3	0.069
arpc1a	actin related protein 2/3 complex, subunit 1A	0.069
cry2b	cryptochrome 2b	0.069
dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.068
adrb3b	adrenergic receptor, beta 3b	0.068
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.068
fas	Fas (TNF receptor superfamily, member 6)	0.068
sestd1	SEC14 and spectrin domains 1	0.068
LOC559090	PWWP domain-containing protein 2A-like	0.068
arid4a	AT rich interactive domain 4A (RBP1-like)	0.068
poll	polymerase (DNA directed), lambda	0.067
tmem93	transmembrane protein 93	0.067
si:ch211-239j15.4	si:ch211-239j15.4	0.067
gmnn	geminin, DNA replication inhibitor	0.067
pnrc2	proline-rich nuclear receptor coactivator 2	0.067
vapal	VAMP (vesicle-associated membrane protein)-associated protein A, like	0.067
glcea	glucuronyl C5-epimerase a	0.067
LOC100334953	cytoplasmic protein NCK1-like	0.067
tceb1b	transcription elongation factor B (SIII), polypeptide 1b	0.066
ube2q2	ubiquitin-conjugating enzyme E2Q family member 2	0.066
cops3	COP9 constitutive photomorphogenic homolog subunit 3	0.066
zgc:55461	zgc:55461	0.066
ccm2	cerebral cavernous malformation 2	0.066
flt4	fms-related tyrosine kinase 4	0.066
ctdnep1a	CTD nuclear envelope phosphatase 1a	0.066
csnk1da	casein kinase 1, delta a	0.066	Mouse Fly
pi4kaa	phosphatidylinositol 4-kinase, catalytic, alpha a	0.066
zfand5b	zinc finger, AN1-type domain 5b	0.066
psmg2	proteasome (prosome, macropain) assembly chaperone 2	0.066
ncapd2	non-SMC condensin I complex, subunit D2	0.066
rpn1	ribophorin I	0.065
rilpl2	Rab interacting lysosomal protein-like 2	0.065
patl1	protein associated with topoisomerase II homolog 1 (yeast)	0.065
spns1	spinster homolog 1 (Drosophila)	0.065
prpf38b	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	0.065
tomm40	translocase of outer mitochondrial membrane 40 homolog (yeast)	0.065
tnrc6b	trinucleotide repeat containing 6B	0.065
atf6	activating transcription factor 6	0.064
slc35e1	solute carrier family 35, member E1	0.064
zgc:92765	zgc:92765	0.064
polr2b	polymerase (RNA) II (DNA directed) polypeptide B	0.064
yipf3	Yip1 domain family, member 3	0.064
mphosph8	M-phase phosphoprotein 8	0.064
si:ch211-153j24.6	si:ch211-153j24.6	0.064
dvl3	dishevelled, dsh homolog 3 (Drosophila)	0.064
hsp90b1	heat shock protein 90, beta (grp94), member 1	0.064	Human
zgc:86870	zgc:86870	0.064
stt3b	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)	0.064	Human
mapk3	mitogen-activated protein kinase 3	0.063
smarcb1a	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a	0.063
zgc:174506	zgc:174506	0.063	Human
taf11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.063
fibp	fibroblast growth factor (acidic) intracellular binding protein	0.063
wipi2	WD repeat domain, phosphoinositide interacting 2	0.063
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.063
zgc:91910	zgc:91910	0.063
sox32	SRY-box containing gene 32	0.063
mfn2	mitofusin 2	0.063
ube2l3b	ubiquitin-conjugating enzyme E2L 3b	0.063
si:ch211-175f11.2	si:ch211-175f11.2	0.063
frzb	frizzled-related protein	0.062
cstf1	cleavage stimulation factor, 3' pre-RNA, subunit 1	0.062
ubxn6	UBX domain protein 6	0.062
rps2	ribosomal protein S2	0.062
LOC100006898	hypothetical protein LOC100006898	0.062
snai1a	snail homolog 1a (Drosophila)	0.062
usp14	ubiquitin specific protease 14 (tRNA-guanine transglycosylase)	0.062
wrb	tryptophan rich basic protein	0.062
zgc:110434	zgc:110434	0.062
LOC100537975	thyroid receptor-interacting protein 11-like	0.062
tmem50a	transmembrane protein 50A	0.062
ern1	endoplasmic reticulum to nucleus signaling 1	0.061
pou5f1	POU domain, class 5, transcription factor 1	0.061
si:dkey-273o13.1	si:dkey-273o13.1	0.061
abcb3l1	ATP-binding cassette, sub-family B (MDR/TAP), member 3 like 1	0.061
hectd1	HECT domain containing 1	0.061
supt6h	suppressor of Ty 6 homolog	0.061
zgc:153063	zgc:153063	0.060
fli1a	friend leukemia integration 1a	0.060
cpsf3l	cleavage and polyadenylation specific factor 3-like	0.060
zgc:64177	zgc:64177	0.060
zgc:92321	zgc:92321	0.060
itpr1a	inositol 1,4,5-triphosphate receptor, type 1a	0.060
mbd3a	methyl-CpG binding domain protein 3a	0.060
pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	0.060
zgc:110337	zgc:110337	0.060
stk35l	serine/threonine kinase 35, like	0.060
extl3	exostoses (multiple)-like 3	0.060
arhgap11a	Rho GTPase activating protein 11A	0.060
pfn2	profilin 2	0.060
map2k7	mitogen-activated protein kinase kinase 7	0.059
ndel1b	nudE nuclear distribution gene E homolog like 1 (A. nidulans) B	0.059
siae	sialic acid acetylesterase	0.059
dcun1d2	DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae)	0.059
ipo7	importin 7	0.059
stk11	serine/threonine kinase 11	0.059
pex13	peroxisome biogenesis factor 13	0.059
arntl1a	aryl hydrocarbon receptor nuclear translocator-like 1a	0.059	Mouse
arntl2	aryl hydrocarbon receptor nuclear translocator-like 2	0.059
c20orf11	c20orf11 homolog (H. sapiens)	0.059
lipf	lipase, gastric	0.059
im:7140452	im:7140452	0.058
ppp2r5d	protein phosphatase 2, regulatory subunit B', delta	0.058
pdia4	protein disulfide isomerase associated 4	0.058
usp25	ubiquitin specific protease 25	0.058
ctr9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.058
ankrd6	ankyrin repeat domain 6	0.058
ctbp1	C-terminal binding protein 1	0.058
tlk2	tousled-like kinase 2	0.058	Human
exoc1	exocyst complex component 1	0.058
pin1	protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1	0.058
yipf4	Yip1 domain family, member 4	0.058
paf1	paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.058
zgc:56340	zgc:56340	0.058	Human Mouse
si:dkey-15j16.2	si:dkey-15j16.2	0.058
sec61b	Sec61 beta subunit	0.058
pgam1b	phosphoglycerate mutase 1b	0.058
pi4k2a	phosphatidylinositol 4-kinase type 2 alpha	0.058
igf2r	insulin-like growth factor 2 receptor	0.058
pitpnbl	phosphatidylinositol transfer protein, beta, like	0.058
rgl2	ral guanine nucleotide dissociation stimulator-like 2	0.057
psmg1	proteasome (prosome, macropain) assembly chaperone 1	0.057
pdcd10a	programmed cell death 10a	0.057
klhl18	kelch-like 18 (Drosophila)	0.057
kdsr	3-ketodihydrosphingosine reductase	0.057
aars	alanyl-tRNA synthetase	0.057
slu7	SLU7 splicing factor homolog (S. cerevisiae)	0.057
atp6v0b	ATPase, H+ transporting, V0 subunit B	0.057
ciao1	cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae)	0.057
calm3b	calmodulin 3b (phosphorylase kinase, delta)	0.057
eif4g2a	eukaryotic translation initiation factor 4, gamma 2a	0.057
ctsl1b	cathepsin L, 1 b	0.057
hif1an	hypoxia-inducible factor 1, alpha subunit inhibitor	0.057
zgc:66415	zgc:66415	0.057
trim8	tripartite motif-containing 8	0.057
arf1l	ADP-ribosylation factor 1 like	0.057
ik	IK cytokine	0.057
vldlr	very low density lipoprotein receptor	0.057
tshz1	teashirt family zinc finger 1	0.056
zgc:92824	zgc:92824	0.056
polrmt	polymerase (RNA) mitochondrial (DNA directed)	0.056
safb	scaffold attachment factor B	0.056
ergic2	ERGIC and golgi 2	0.056
ck2a1	casein kinase 2 alpha 1	0.056
tmem9b	TMEM9 domain family, member B	0.056
zgc:92867	zgc:92867	0.056
ddx26b	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B	0.056
wu:fb80e01	wu:fb80e01	0.056
zgc:85882	zgc:85882	0.056
ephx1	epoxide hydrolase 1, microsomal (xenobiotic)	0.056
nutf2	nuclear transport factor 2	0.056
atl2	atlastin GTPase 2	0.056
scd	stearoyl-CoA desaturase (delta-9-desaturase)	0.055
rasgef1ba	RasGEF domain family, member 1Ba	0.055
usp10	ubiquitin specific peptidase 10	0.055
wwp2	WW domain containing E3 ubiquitin protein ligase 2	0.055
gadd45bb	growth arrest and DNA-damage-inducible, beta b	0.055
zgc:114199	zgc:114199	0.055
ehmt2	euchromatic histone-lysine N-methyltransferase 2	0.055
wu:fe11g03	wu:fe11g03	0.055
rab20	RAB20, member RAS oncogene family	0.055
itga5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.055
m6pr	mannose-6-phosphate receptor (cation dependent)	0.055
gosr1	golgi SNAP receptor complex member 1	0.055
zgc:162630	zgc:162630	0.055
zgc:110801	zgc:110801	0.055
hax1	HCLS1 associated protein X-1	0.055
mtfr1	mitochondrial fission regulator 1	0.054
h2afx	H2A histone family, member X	0.054
dnajb6b	DnaJ (Hsp40) homolog, subfamily B, member 6b	0.054
eny2	enhancer of yellow 2 homolog (Drosophila)	0.054
ctdsp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	0.054
sumo2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.054
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.054
erh	enhancer of rudimentary homolog (Drosophila)	0.054
tmem147	transmembrane protein 147	0.054
cul4b	cullin 4B	0.054
LOC100536876	probable ATP-dependent RNA helicase DDX41-like	0.054
ppp2r5eb	protein phosphatase 2, regulatory subunit B', epsilon isoform b	0.054
atl3	atlastin 3	0.054
sec23ip	SEC23 interacting protein	0.054
ahrrb	aryl-hydrocarbon receptor repressor b	0.054
pdzd11	PDZ domain containing 11	0.054
ncaph	non-SMC condensin I complex, subunit H	0.053
sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.053	Human
zgc:66100	zgc:66100	0.053
slc12a9	solute carrier family 12 (potassium/chloride transporters), member 9	0.053
mknk1	MAP kinase interacting serine/threonine kinase 1	0.053
usp4	ubiquitin specific protease 4 (proto-oncogene)	0.053
lin7c	lin-7 homolog C (C. elegans)	0.053
polb	polymerase (DNA directed), beta	0.053
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.053
ikbkg	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.053
tlr4bb	toll-like receptor 4b, duplicate b	0.053
lrrfip1a	leucine rich repeat (in FLII) interacting protein 1a	0.053
fxr1	fragile X mental retardation, autosomal homolog 1	0.053
kirrel3l	kin of IRRE like 3 like	0.053
gtf2b	general transcription factor IIB	0.053
phf17	PHD finger protein 17	0.053
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.053
LOC100330405	transmembrane protein 176B-like	0.053
a1cf	apobec1 complementation factor	0.053
usp33	ubiquitin specific peptidase 33	0.053
ctnnbl1	catenin, beta like 1	0.053
rcbtb1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1	0.053
cdc34b	cell division cycle 34 homolog (S. cerevisiae) b	0.053
slc30a5	solute carrier family 30 (zinc transporter), member 5	0.052
zgc:92203	zgc:92203	0.052
psmf1	proteasome (prosome, macropain) inhibitor subunit 1	0.052
zgc:85812	zgc:85812	0.052
map1lc3a	microtubule-associated protein 1 light chain 3 alpha	0.052
casp6	caspase 6, apoptosis-related cysteine peptidase	0.052
mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.052	Human Mouse Worm
si:ch211-147d7.3	si:ch211-147d7.3	0.052
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.052
maea	macrophage erythroblast attacher	0.052
clk4a	CDC-like kinase 4a	0.052
ppp1caa	protein phosphatase 1, catalytic subunit, alpha isoform a	0.052
med27	mediator complex subunit 27	0.052
zgc:77304	zgc:77304	0.052
epas1a	endothelial PAS domain protein 1a	0.052
hdac3	histone deacetylase 3	0.052
h3f3d	H3 histone, family 3D	0.052
dda1	DET1 and DDB1 associated 1	0.052
zgc:56419	zgc:56419	0.052
hnrnph1	heterogeneous nuclear ribonucleoprotein H1	0.052
ankrd13c	ankyrin repeat domain 13C	0.052
sec23b	Sec23 homolog B (S. cerevisiae)	0.052
rangap1	Ran GTPase activating protein 1	0.052
rap2b	RAP2B, member of RAS oncogene family	0.052
zgc:113518	zgc:113518	0.052
eaf1	ELL associated factor 1	0.051
zgc:92014	zgc:92014	0.051
arfip2b	ADP-ribosylation factor interacting protein 2b	0.051
sb:cb134	sb:cb134	0.051
zgc:64213	zgc:64213	0.051
g6pd	glucose-6-phosphate dehydrogenase	0.051
helb	helicase (DNA) B	0.051
srsf1b	serine/arginine-rich splicing factor 1b	0.051
lrrfip2	leucine rich repeat (in FLII) interacting protein 2	0.051
arfgap2	ADP-ribosylation factor GTPase activating protein 2	0.051
thraa	thyroid hormone receptor alpha a	0.051
zgc:100829	zgc:100829	0.051
atp13a2	ATPase type 13A2	0.051
rragc	Ras-related GTP binding C	0.051
galca	galactosylceramidase a	0.051
zmynd19	zinc finger, MYND domain containing 19	0.051
cxxc1	CXXC finger 1 (PHD domain)	0.051
rfc4	replication factor C (activator 1) 4	0.051
atf1	activating transcription factor 1	0.051
fshr	follicle stimulating hormone receptor	0.050
vac14	vac14 homolog (S. cerevisiae)	0.050
ggnbp2	gametogenetin binding protein 2	0.050
taldo1	transaldolase 1	0.050
rgs18	regulator of G-protein signaling 18	0.050
eif1b	eukaryotic translation initiation factor 1B	0.050
pole	polymerase (DNA directed), epsilon	0.050
u2af1	U2(RNU2) small nuclear RNA auxiliary factor 1	0.050
nfe2l3	nuclear factor (erythroid-derived 2)-like 3	0.050
mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.050
zgc:152900	zgc:152900	0.050
ptdss1	phosphatidylserine synthase 1	0.050
eef2l2	eukaryotic translation elongation factor 2, like 2	0.050
pbrm1l	polybromo 1, like	0.050
im:7141132	im:7141132	0.050
me2	malic enzyme 2, NAD(+)-dependent, mitochondrial	0.050
slc48a1b	solute carrier family 48 (heme transporter), member 1b	0.049
vps37a	vacuolar protein sorting 37A	0.049
ubtd2	ubiquitin domain containing 2	0.049
esco2	establishment of cohesion 1 homolog 2	0.049
tuba8l4	tubulin, alpha 8 like 4	0.049
slmo2	slowmo homolog 2 (Drosophila)	0.049
zgc:73265	zgc:73265	0.049
med19b	mediator complex subunit 19b	0.049
plekha1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.049
jmjd6	jumonji domain containing 6	0.049
zgc:56525	zgc:56525	0.049
zgc:56259	zgc:56259	0.049
ppp1r10	protein phosphatase 1, regulatory subunit 10	0.049
ptpn11a	protein tyrosine phosphatase, non-receptor type 11, a	0.049
ftsjd2	FtsJ methyltransferase domain containing 2	0.049
exoc7	exocyst complex component 7	0.049
cyp2aa4	cytochrome P450, family 2, subfamily AA, polypeptide 4	0.049
rps6kb1b	ribosomal protein S6 kinase b, polypeptide 1b	0.049
sept9a	septin 9a	0.049
epc2	enhancer of polycomb homolog 2 (Drosophila)	0.049
ryk	receptor-like tyrosine kinase	0.049
zgc:92392	zgc:92392	0.049
zgc:103580	zgc:103580	0.048
si:dkey-177p2.3	si:dkey-177p2.3	0.048
hic1l	hypermethylated in cancer 1 like	0.048
spsb1	splA/ryanodine receptor domain and SOCS box containing 1	0.048
cisd1	CDGSH iron sulfur domain 1	0.048
ptprja	protein tyrosine phosphatase, receptor type, J a	0.048
slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.048
ppp2r1b	protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform	0.048
maf1	MAF1 homolog (S. cerevisiae)	0.048
hk1	hexokinase 1	0.048
wnt10a	wingless-type MMTV integration site family, member 10a	0.048
ppil4	peptidylprolyl isomerase (cyclophilin)-like 4	0.048
gbp1	guanylate binding protein 1	0.048
ptplb	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b	0.048
xirp1	xin actin-binding repeat containing 1	0.047
hgs	hepatocyte growth factor-regulated tyrosine kinase substrate	0.047
timp2b	tissue inhibitor of metalloproteinase 2b	0.047
zgc:158564	zgc:158564	0.047
smpd4	sphingomyelin phosphodiesterase 4	0.047
zgc:110468	zgc:110468	0.047
zgc:113421	zgc:113421	0.047
tmed2	transmembrane emp24 domain trafficking protein 2	0.047
aldh16a1	aldehyde dehydrogenase 16 family, member A1	0.047
zgc:64051	zgc:64051	0.047
zgc:77155	zgc:77155	0.047
caprin1a	cell cycle associated protein 1a	0.047
gtf2f1	general transcription factor IIF, polypeptide 1	0.047
amfr	autocrine motility factor receptor	0.047	Human
snx3	sorting nexin 3	0.047
fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.047	Human Yeast
gmppb	GDP-mannose pyrophosphorylase B	0.047
ppp2r5ea	protein phosphatase 2, regulatory subunit B', epsilon isoform a	0.047
LOC568379	von Willebrand factor A domain-containing protein 1-like	0.047
mlx	MAX-like protein X	0.047
ext1c	exostoses (multiple) 1c	0.047
zgc:55876	zgc:55876	0.047
fmnl2b	formin-like 2b	0.047
klhl11	kelch-like 11 (Drosophila)	0.047
hspb8	heat shock protein, alpha-crystallin-related, b8	0.047
trim13	tripartite motif-containing 13	0.047
ncapg	non-SMC condensin I complex, subunit G	0.047
hormad1	HORMA domain containing 1	0.047
npepl1	aminopeptidase-like 1	0.047
rbm4.1	RNA binding motif protein 4.1	0.046
cdc42l	cell division cycle 42, like	0.046
shroom4	shroom family member 4	0.046
zgc:92022	zgc:92022	0.046
zgc:110682	zgc:110682	0.046
immt	inner membrane protein, mitochondrial (mitofilin)	0.046
zgc:101581	zgc:101581	0.046
derl2	Der1-like domain family, member 2	0.046
chp2	calcineurin B homologous protein 2	0.046
adnp2a	ADNP homeobox 2a	0.046
hdc	histidine decarboxylase	0.046
aebp2	AE binding protein 2	0.046
lama4	laminin, alpha 4	0.046
notch2	notch homolog 2	0.046
napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.046
si:ch73-60i13.2	si:ch73-60i13.2	0.046
srpr	signal recognition particle receptor (docking protein)	0.046
mecp2	methyl CpG binding protein 2	0.046
upp2	uridine phosphorylase 2	0.046
zgc:110308	zgc:110308	0.046
runx2b	runt-related transcription factor 2b	0.046
gins3	GINS complex subunit 3	0.046
rpl35a	ribosomal protein L35a	0.046
zgc:73100	zgc:73100	0.046
zgc:85866	zgc:85866	0.046
fgf10a	fibroblast growth factor 10a	0.046
cyp11b2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.046
si:dkey-114g7.4	si:dkey-114g7.4	0.045
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.045
yrk	Yes-related kinase	0.045
traf7	TNF receptor-associated factor 7	0.045
ttc1	tetratricopeptide repeat domain 1	0.045
puf60b	poly-U binding splicing factor b	0.045