IMP: Integrative Multi-species Prediction

Danio rerio

15 genes annotated in zebrafish

neural nucleus development

The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neural nucleus development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "neural nucleus development" (in gray)

Name	Description	Probability	Func Analog Organism
fzd3a	frizzled homolog 3a	0.829
scrib	scribbled homolog (Drosophila)	0.654	Mouse
mbp	myelin basic protein	0.585	Human
nadl1.1	neural adhesion molecule L1.1	0.578
fgf3	fibroblast growth factor 3	0.568
crb2a	crumbs homolog 2a	0.554
mpz	myelin protein zero	0.423
phox2a	paired-like homeobox 2a	0.398
mxi1	max interacting protein	0.380
dlx5a	distal-less homeobox gene 5a	0.348
ywhaqb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b	0.312	Human
twist3	twist3	0.287
dlx4a	distal-less homeobox gene 4a	0.249
gpia	glucose phosphate isomerase a	0.243
sox1a	SRY-box containing gene 1a	0.231
guca1c	guanylate cyclase activator 1C	0.209
fstl1b	follistatin-like 1b	0.204
gbx1	gastrulation brain homeobox 1	0.203
bmp2a	bone morphogenetic protein 2a	0.199
fgf10a	fibroblast growth factor 10a	0.196	Zebrafish
zgc:65851	zgc:65851	0.194
lama1	laminin, alpha 1	0.190
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.187
plp1a	proteolipid protein 1a	0.183	Human
fzd7a	frizzled homolog 7a	0.183
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.182
zgc:66382	zgc:66382	0.179
otpb	orthopedia homolog b	0.150
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.140
grhl2b	grainyhead-like 2b (Drosophila)	0.132
si:dkeyp-7c9.1	si:dkeyp-7c9.1	0.132
hoxa2b	homeo box A2b	0.129	Zebrafish
ephb4b	eph receptor B4b	0.123
acvr1b	activin A receptor, type IB	0.121
isl1	islet1	0.120
alcamb	activated leukocyte cell adhesion molecule b	0.108
hoxa13b	homeo box A13b	0.105
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.098
cd99l2	CD99 antigen-like 2	0.096
klf4	Kruppel-like factor 4	0.096
itm2bb	integral membrane protein 2Bb	0.095
prdm14	PR domain containing 14	0.094
egr2b	early growth response 2b	0.092
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.091
atoh1a	atonal homolog 1a	0.089
alpi	alkaline phosphatase, intestinal	0.088
bactin1	bactin1	0.087	Human
pkm2a	pyruvate kinase, muscle, a	0.085
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.084
nkx2.2a	NK2 transcription factor related 2a	0.083
sb:cb730	sb:cb730	0.083
ndufa4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4	0.080
her8a	hairy-related 8a	0.074
ywhaqa	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a	0.072	Human
copb2	coatomer protein complex, subunit beta 2	0.072
calm3b	calmodulin 3b (phosphorylase kinase, delta)	0.071
disp1	dispatched homolog 1 (Drosophila)	0.070
tectb	tectorin beta	0.069
fzd8a	frizzled homolog 8a	0.068	Zebrafish
nkx2.1a	NK2 homeobox 1a	0.063
nes	nestin	0.063
crb2b	crumbs homolog 2b	0.062
dbx1b	developing brain homeobox 1b	0.061
dharma	dharma	0.060
vangl2	vang-like 2 (van gogh, Drosophila)	0.060
msxc	muscle segment homeobox C	0.060
fzd5	frizzled homolog 5	0.060	Zebrafish
sp5l	Sp5 transcription factor-like	0.060
otx1a	orthodenticle homolog 1a	0.059
ek1	eph-like kinase 1	0.059
irx3a	iroquois homeobox protein 3a	0.058
appb	amyloid beta (A4) precursor protein b	0.058
b4galt4	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4	0.056
csad	cysteine sulfinic acid decarboxylase	0.056
LOC100003514	protein kinase C alpha type-like	0.054
crb3b	crumbs homolog 3b	0.054
mnx1	motor neuron and pancreas homeobox 1	0.052
prkci	protein kinase C, iota	0.051
gro1	groucho 1	0.050
cfl2l	cofilin 2, like	0.050
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.050
six3a	sine oculis homeobox homolog 3a	0.049
zgc:112180	zgc:112180	0.049
plp1b	proteolipid protein 1b	0.049	Human
loxl2b	lysyl oxidase-like 2b	0.048
grk7a	G-protein-coupled receptor kinase 7a	0.047
wnt5b	wingless-type MMTV integration site family, member 5b	0.046
boc	brother of CDO	0.046
spry2	sprouty homolog 2	0.046
dla	deltaA	0.045
olig3	oligodendrocyte transcription factor 3	0.044
insm1b	insulinoma-associated 1b	0.044
si:dkey-97i18.2	si:dkey-97i18.2	0.044
sumo3a	SMT3 suppressor of mif two 3 homolog 3a	0.044
foxa2	forkhead box A2	0.044
lhx1b	LIM homeobox 1b	0.043
hoxb1a	homeo box B1a	0.042
ift88	intraflagellar transport 88 homolog	0.041
zgc:110298	zgc:110298	0.041
wu:fc24e06	wu:fc24e06	0.040
hoxc1a	homeo box C1a	0.040	Zebrafish
sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.040
stm	starmaker	0.039
sall4	sal-like 4 (Drosophila)	0.039
dkk1b	dickkopf 1b	0.038
atp6v0ca	ATPase, H+ transporting, lysosomal, V0 subunit c, a	0.037
cx30.3	connexin 30.3	0.037
entpd3	ectonucleoside triphosphate diphosphohydrolase 3	0.037
neurod4	neurogenic differentiation 4	0.037
lhx5	LIM homeobox 5	0.037
bmp7b	bone morphogenetic protein 7b	0.036
dbx1a	developing brain homeobox 1a	0.036
arr3b	arrestin 3b, retinal (X-arrestin)	0.036
ndr2	nodal-related 2	0.035
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.035
zgc:111961	zgc:111961	0.035
ephb3a	eph receptor B3a	0.035
dlx2b	distal-less homeobox gene 2b	0.035
lmbr1l	limb region 1 like	0.034
nipblb	novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)	0.034
pdgfaa	platelet-derived growth factor alpha a	0.034
crb1	crumbs homolog 1 (Drosophila)	0.034
eng1b	engrailed 1b	0.033
meis3	myeloid ecotropic viral integration site 3	0.033
acvr2a	activin receptor IIa	0.033
lfng	lunatic fringe homolog	0.033
zgc:92745	zgc:92745	0.033
sparc	secreted acidic cysteine rich glycoprotein	0.033
pitx2	paired-like homeodomain transcription factor 2	0.032	Mouse
prrx1a	paired related homeobox 1a	0.032	Zebrafish
si:ch211-232m7.1	si:ch211-232m7.1	0.032
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.032
ncs1a	neuronal calcium sensor 1a	0.031
celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.031
irf6	interferon regulatory factor 6	0.031
wu:fb63c04	wu:fb63c04	0.031
pou1f1	POU domain, class 1, transcription factor 1	0.030
nrarpb	notch-regulated ankyrin repeat protein b	0.030
polr2d	polymerase (RNA) II (DNA directed) polypeptide D	0.030
ckbb	creatine kinase, brain b	0.030
vcanb	versican b	0.029
hs3st3b1a	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a	0.029
nkx1.2la	NK1 transcription factor related 2-like,a	0.028
si:dkeyp-66d7.2	si:dkeyp-66d7.2	0.028
slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.028
lhx1a	LIM homeobox 1a	0.028
zgc:112018	zgc:112018	0.027
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.026
vasp	vasodilator-stimulated phosphoprotein	0.026
pink1	PTEN induced putative kinase 1	0.025
nhsl1b	NHS-like 1b	0.025
hoxa1a	homeo box A1a	0.025	Zebrafish Mouse
uchl1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.025
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.025
skia	nuclear oncoprotein skia	0.025
six1a	sine oculis homeobox homolog 1a	0.025
zic4	zic family member 4	0.025
eya1	eyes absent homolog 1	0.025
gata2a	GATA-binding protein 2a	0.025
suv420h2	suppressor of variegation 4-20 homolog 2 (Drosophila)	0.024
dusp4	dual specificity phosphatase 4	0.024
dacha	dachshund a	0.024
ywhaba	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a	0.024
admp	anti-dorsalizing morphogenic protein	0.024
slc25a3b	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b	0.024
ca2	carbonic anhydrase II	0.024
syne1a	spectrin repeat containing, nuclear envelope 1a	0.024
si:dkey-246k9.1	si:dkey-246k9.1	0.023
ywhae1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1	0.023	Human
six4b	sine oculis homeobox homolog 4b	0.023
neurod	neurogenic differentiation	0.023
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.023
gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.023
hmx3	homeo box (H6 family) 3	0.023
sfrp1a	secreted frizzled-related protein 1a	0.023
lama5	laminin, alpha 5	0.023
nova2	neuro-oncological ventral antigen 2	0.022
si:ch211-197h24.9	si:ch211-197h24.9	0.022
cntn1b	contactin 1b	0.022
irx4a	iroquois homeobox protein 4a	0.022
sulf1	sulfatase 1	0.022
vim	vimentin	0.022
hoxd11a	homeo box D11a	0.022
LOC100007758	novel protein similar to vertebrate SLIT and NTRK-like family, member 3 (SLITRK3)	0.022
pdlim7	PDZ and LIM domain 7	0.021
lamc1	laminin, gamma 1	0.021
sdc2	syndecan 2	0.021
hoxd4a	homeo box D4a	0.021
tlx2	T-cell leukemia, homeobox 2	0.021
crb3a	crumbs homolog 3a	0.021
hpca	hippocalcin	0.021
arhgap28	Rho GTPase activating protein 28	0.020
sox21b	SRY-box containing gene 21 b	0.020
prkcz	protein kinase C, zeta	0.020	Zebrafish
nkx2.1b	NK2 homeobox 1b	0.020	Human Mouse
wu:fc18c07	wu:fc18c07	0.020
hoxb5b	homeo box B5b	0.020
fzd7b	frizzled homolog 7b	0.020	Zebrafish
sb:cb101	sb:cb101	0.019
fgf17	fibroblast growth factor 17	0.019	Zebrafish
nrp2b	neuropilin 2b	0.019
hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	0.019
dlx1a	distal-less homeobox gene 1a	0.019
pou3f3a	POU class 3 homeobox 3a	0.019
rxrbb	retinoid x receptor, beta b	0.019
zgc:91860	zgc:91860	0.018
unc5c	unc-5 homolog C (C. elegans)	0.018
lrrc17	leucine rich repeat containing 17	0.018
onecutl	one cut domain, family member, like	0.018
bglap	bone gamma-carboxyglutamate (gla) protein	0.018
eif2ak3	eukaryotic translation initiation factor 2-alpha kinase 3	0.018
srsf1a	serine/arginine-rich splicing factor 1a	0.017
eno1	enolase 1, (alpha)	0.017
efnb1	ephrin B1	0.017
cdc42	cell division cycle 42	0.017	Human
tbx16	T-box gene 16	0.017
krt8	keratin 8	0.017
tbr1b	T-box, brain, 1b	0.017
ntrk2a	neurotrophic tyrosine kinase, receptor, type 2a	0.017
slc3a2	solute carrier family 3, member 2	0.017
ube2na	ubiquitin-conjugating enzyme E2Na	0.017
spock3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	0.017
gata5	GATA-binding protein 5	0.017
ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.017
nr6a1a	nuclear receptor subfamily 6, group A, member 1a	0.016
wu:fb39a06	wu:fb39a06	0.016
mpp5a	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)	0.016
pea3	ETS-domain transcription factor pea3	0.016
runx3	runt-related transcription factor 3	0.016
hist2h2l	histone 2, H2, like	0.016
atoh7	atonal homolog 7	0.016
nkx2.2b	NK2 transcription factor related 2b	0.016
pmp22a	peripheral myelin protein 22a	0.016
pknox1.2	pbx/knotted 1 homeobox 1.2	0.016
cntn1a	contactin 1a	0.016
zic6	zic family member 6	0.016
meis4.1a	myeloid ecotropic viral integration site 4.1a	0.015
irx5a	iroquois homeobox protein 5a	0.015
shha	sonic hedgehog a	0.015
vcl	vinculin	0.015
pax6b	paired box gene 6b	0.015
pgm1	phosphoglucomutase 1	0.015
tcea3	transcription elongation factor A (SII), 3	0.015
zgc:77836	zgc:77836	0.015
hsp47	heat shock protein 47	0.015
tbx1	T-box 1	0.015
tmem59l	transmembrane protein 59-like and transmembrane protein 59-like	0.015
lrrn1	leucine rich repeat neuronal 1	0.015
sb:cb322	sb:cb322	0.015
vsx1	visual system homeobox 1 homolog, chx10-like	0.015
lft1	lefty1	0.015
emx1	empty spiracles homeobox 1	0.014
ube2i2	ubiquitin-conjugating enzyme E2I2	0.014
actc1a	actin, alpha, cardiac muscle 1a	0.014
lamb1a	laminin, beta 1a	0.014
utrn	utrophin	0.014
ncor1	nuclear receptor co-repressor 1	0.014
kif5aa	kinesin family member 5A, a	0.014
si:dkeyp-63d11.7	si:dkeyp-63d11.7	0.014
otomp	otolith matrix protein	0.014
tpp1	tripeptidyl peptidase I	0.014
nadl1.2	neural adhesion molecule L1.2	0.014
six2a	sine oculis-related homeobox 2a	0.014
rx3	retinal homeobox gene 3	0.014
ezr	ezrin	0.014
cdh2	cadherin 2, neuronal	0.014
dlx4b	distal-less homeobox gene 4b	0.014
cldnh	claudin h	0.014
foxg1a	forkhead box G1a	0.014
dctn1a	dynactin 1a	0.013
gnl2	guanine nucleotide binding protein-like 2 (nucleolar)	0.013
lmo3	LIM domain only 3	0.013
pvrl2l	poliovirus receptor-related 2 like	0.013
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.013
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.013
zgc:136817	zgc:136817	0.013
ctsf	cathepsin F	0.013
her5	hairy-related 5	0.013
lbx1a	ladybird homeobox 1a	0.013
rhoab	ras homolog gene family, member Ab	0.013
gli2a	GLI-Kruppel family member GLI2a	0.013	Zebrafish
trpa1b	transient receptor potential cation channel, subfamily A, member 1b	0.013
il17rd	interleukin 17 receptor D	0.013
lrtm2	leucine-rich repeats and transmembrane domains 2	0.013
jhdm1da	jumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae)	0.013
celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	0.013
her15.1	hairy and enhancer of split-related 15.1	0.013
crestin	crestin	0.012
rassf8b	Ras association (RalGDS/AF-6) domain family 8b	0.012
pcdh18b	protocadherin 18b	0.012
hoxc6a	homeo box C6a	0.012
hoxa3a	homeo box A3a	0.012
bty	bloodthirsty	0.012
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.012
itga5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.012
slc12a7b	solute carrier family 12, member 7b	0.012
hsp90b1	heat shock protein 90, beta (grp94), member 1	0.012
s1pr1	sphingosine-1-phosphate receptor 1	0.012
emx2	empty spiracles homeobox 2	0.012
pob	partial optokinetic response b	0.012
cadps2	Ca2+-dependent activator protein for secretion 2	0.012
syt9a	synaptotagmin IXa	0.011
evx1	even-skipped homeobox 1	0.011
otop1	otopetrin 1	0.011
her4.2	hairy-related 4.2	0.011
ankrd12	ankyrin repeat domain 12	0.011
cyt1	type I cytokeratin, enveloping layer	0.011
hoxa9b	homeo box A9b	0.011
ptpn9a	protein tyrosine phosphatase, non-receptor type 9, a	0.011
ephb4a	eph receptor B4a	0.011
calm1b	calmodulin 1b	0.011
pdip5	protein disulfide isomerase-related protein (provisional)	0.011
dsc2l	desmocollin 2 like	0.011
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.011
ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.011
msxd	muscle segment homeobox D	0.011
hoxa11b	homeo box A11b	0.011
calca	calcitonin/calcitonin-related polypeptide, alpha	0.011
lhx6	LIM homeobox 6	0.011
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.011
taf1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.011
olig2	oligodendrocyte lineage transcription factor 2	0.011
fabp7a	fatty acid binding protein 7, brain, a	0.011
alas1	aminolevulinate, delta-, synthetase 1	0.011
ctssb.2	cathepsin S, b.2	0.011
im:7137555	im:7137555	0.011
rhpn2	rhophilin, Rho GTPase binding protein 2	0.010
cplx4a	complexin 4a	0.010
phex	phosphate regulating gene with homologues to endopeptidases on the X chromosome	0.010
khdrbs1a	KH domain containing, RNA binding, signal transduction associated 1a	0.010
hoxb1b	homeo box B1b	0.010	Zebrafish Mouse
tpi1b	triosephosphate isomerase 1b	0.010
ppp3cca	protein phosphatase 3, catalytic subunit, gamma isozyme, a	0.010
sb:cb1008	sb:cb1008	0.010