IMP: Integrative Multi-species Prediction

Danio rerio

3 genes annotated in zebrafish

ubiquitin dependent protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

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Name	Description	Probability	Func Analog Organism
psmd6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.974
psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.935	Human Yeast
psmb1	proteasome (prosome, macropain) subunit, beta type, 1	0.929
zgc:92775	zgc:92775	0.916
psmb7	proteasome (prosome, macropain) subunit, beta type, 7	0.911	Yeast
psma8	proteasome (prosome, macropain) subunit, alpha type, 8	0.875	Yeast
psma6a	proteasome (prosome, macropain) subunit, alpha type, 6a	0.782	Yeast
psmd4b	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4b	0.775	Yeast Worm
psmb3	proteasome (prosome, macropain) subunit, beta type, 3	0.745	Yeast
vcp	valosin containing protein	0.742
psmd1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.742	Yeast
psmc1b	proteasome (prosome, macropain) 26S subunit, ATPase, 1b	0.719
psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.712
psmc5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.684	Human Yeast Worm
psmb2	proteasome (prosome, macropain) subunit, beta type, 2	0.681	Yeast
psmb5	proteasome (prosome, macropain) subunit, beta type, 5	0.676
ccnb1	cyclin B1	0.653
usp5	ubiquitin specific protease 5	0.630	Human Fly
ck2b	casein kinase 2 beta	0.598
psmc4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.595	Yeast
psma1	proteasome (prosome, macropain) subunit, alpha type, 1	0.550
psmc6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.547
kif23	kinesin family member 23	0.513
bc2	putative breast adenocarcinoma marker	0.509	Fly
supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	0.506
hyou1	hypoxia up-regulated 1	0.496
evx1	even-skipped homeobox 1	0.495
wnt4a	wingless-type MMTV integration site family, member 4a	0.481
aurkb	aurora kinase B	0.474
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.474
ube2d1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.463	Human Yeast
arf2	ADP-ribosylation factor 2	0.460
baxa	bcl2-associated X protein, a	0.457
adrm1b	adhesion regulating molecule 1b	0.444
psmb6	proteasome (prosome, macropain) subunit, beta type, 6	0.418	Yeast
rab1a	RAB1A, member RAS oncogene family	0.416
hspa4b	heat shock protein 4b	0.412
chuk	conserved helix-loop-helix ubiquitous kinase	0.412
cdc20	cell division cycle 20 homolog	0.399	Human Yeast Worm Fly
psmd13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.397	Yeast
tmed2	transmembrane emp24 domain trafficking protein 2	0.365
zgc:123326	zgc:123326	0.362
plk1	polo-like kinase 1 (Drosophila)	0.362	Human
zgc:86903	zgc:86903	0.357
max	myc-associated factor X	0.355
sirt1	sirtuin (silent mating type information regulation 2 homolog) 1	0.340
cnot6	CCR4-NOT transcription complex, subunit 6	0.333
ddx42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42	0.306
btg2	B-cell translocation gene 2	0.305
syvn1	synovial apoptosis inhibitor 1, synoviolin	0.296	Human
zgc:153910	zgc:153910	0.295
zgc:55448	zgc:55448	0.293
si:ch211-69g19.2	si:ch211-69g19.2	0.291
psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.288
psmb4	proteasome (prosome, macropain) subunit, beta type, 4	0.288	Yeast
ccna2	cyclin A2	0.282
psma4	proteasome (prosome, macropain) subunit, alpha type, 4	0.279	Yeast
zgc:110116	zgc:110116	0.275
nploc4	nuclear protein localization 4 homolog (S. cerevisiae)	0.271	Worm
ubin	ataxin-1 ubiquitin-like interacting protein	0.271	Human
lancl1	LanC antibiotic synthetase component C-like 1 (bacterial)	0.270
si:ch211-239j15.4	si:ch211-239j15.4	0.268
psmc1a	proteasome (prosome, macropain) 26S subunit, ATPase, 1a	0.268
ube2g2	ubiquitin-conjugating enzyme E2G 2	0.267
csnk1db	casein kinase 1, delta b	0.265	Mouse Fly
psmc3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.263	Yeast
eif1b	eukaryotic translation initiation factor 1B	0.257
ccnb2	cyclin B2	0.256
dnm1l	dynamin 1-like	0.254
flii	flightless I homolog (Drosophila)	0.253
rqcd1	RCD1 required for cell differentiation1 homolog (S. pombe)	0.251
kpna4	karyopherin alpha 4 (importin alpha 3)	0.251
faf2	Fas associated factor family member 2	0.251
psmd2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.248
srsf11	serine/arginine-rich splicing factor 11	0.248
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.246
gdi2	GDP dissociation inhibitor 2	0.244
suv39h1b	suppressor of variegation 3-9 homolog 1b	0.240
tia1l	cytotoxic granule-associated RNA binding protein 1, like	0.234
trim55b	tripartite motif-containing 55b	0.234
capn2b	calpain 2, (m/II) large subunit b	0.231
gins3	GINS complex subunit 3	0.213
zgc:174506	zgc:174506	0.213	Human
psmd11a	proteasome (prosome, macropain) 216S subunit, non-ATPase, 11a	0.212	Human Worm
nexn	nexilin (F actin binding protein)	0.211
cnot8	CCR4-NOT transcription complex, subunit 8	0.208
fbxw11a	F-box and WD-40 domain protein 11a	0.208	Human Mouse
smndc1	survival motor neuron domain containing 1	0.207
psmd11b	proteasome (prosome, macropain) 216S subunit, non-ATPase, 11b	0.205	Human Yeast Worm
foxb1.2	forkhead box B1.2	0.203
lama4	laminin, alpha 4	0.203
cdt1	chromatin licensing and DNA replication factor 1	0.203
ciapin1	cytokine induced apoptosis inhibitor 1	0.199
zgc:56200	zgc:56200	0.199
birc5a	baculoviral IAP repeat-containing 5a	0.199
atxn2l	ataxin 2-like	0.199
pxn	paxillin	0.199
arpp19a	cAMP-regulated phosphoprotein 19a	0.197
zgc:103652	zgc:103652	0.195
srsf1a	serine/arginine-rich splicing factor 1a	0.194
cry2b	cryptochrome 2b	0.194
zfr	zinc finger RNA binding protein	0.193
blmh	bleomycin hydrolase	0.192
mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.190
setd7	SET domain containing (lysine methyltransferase) 7	0.190
cry4	cryptochrome 4	0.188
hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.188
ubc	ubiquitin C	0.188
gro2	groucho 2	0.187
dirc2	disrupted in renal carcinoma 2	0.186
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.185
im:7142942	im:7142942	0.184
psma5	proteasome (prosome, macropain) subunit, alpha type,5	0.183	Yeast
cand1	cullin-associated and neddylation-dissociated 1	0.183
efnb2a	ephrin B2a	0.180
dnaja2l	DnaJ (Hsp40) homolog, subfamily A, member 2, like	0.178
bsdc1	BSD domain containing 1	0.178
bnip3lb	BCL2/adenovirus E1B interacting protein 3-like b	0.176
zfand2a	zinc finger, AN1-type domain 2A	0.175
orc1	origin recognition complex, subunit 1	0.175
mapkapk2a	mitogen-activated protein kinase-activated protein kinase 2a	0.172
LOC100330405	transmembrane protein 176B-like	0.171
dctn5	dynactin 5	0.171
ube2l3a	ubiquitin-conjugating enzyme E2L 3a	0.171	Mouse
zgc:56376	zgc:56376	0.169
exoc3	exocyst complex component 3	0.168
rbm8a	RNA binding motif protein 8A	0.166
nasp	nuclear autoantigenic sperm protein (histone-binding)	0.166
zgc:55671	zgc:55671	0.165
chmp4b	chromatin modifying protein 4B	0.165
cdc37	cell division cycle 37 homolog (S. cerevisiae)	0.163
zgc:92867	zgc:92867	0.163
extl3	exostoses (multiple)-like 3	0.163
dnajc3	DnaJ (Hsp40) homolog, subfamily C, member 3	0.162
ywhaba	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a	0.162
ik	IK cytokine	0.160
axin1	axin 1	0.160	Mouse
zgc:55512	zgc:55512	0.160	Yeast Fly
elof1	elongation factor 1 homolog (S. cerevisiae)	0.160
rapsn	receptor-associated protein of the synapse, 43kD	0.159
zgc:171495	zgc:171495	0.158
dusp1	dual specificity phosphatase 1	0.158
micall2a	mical-like 2a	0.157
tsc22d2	TSC22 domain family 2 and TSC22 domain family, member 2	0.156
rab5aa	RAB5A, member RAS oncogene family, a	0.154
ppp2cb	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	0.153	Mouse
zgc:91910	zgc:91910	0.153
slu7	SLU7 splicing factor homolog (S. cerevisiae)	0.152
LOC100002625	similar to KIAA0311	0.151
rmnd5b	required for meiotic nuclear division 5 homolog B (S. cerevisiae)	0.151
calm3b	calmodulin 3b (phosphorylase kinase, delta)	0.149
tacc3	transforming, acidic coiled-coil containing protein 3	0.149
csnk1g2a	casein kinase 1, gamma 2a	0.148
map2k4a	mitogen-activated protein kinase kinase 4a	0.145
trim13	tripartite motif-containing 13	0.144
snai1a	snail homolog 1a (Drosophila)	0.144
psma2	proteasome (prosome, macropain) subunit, alpha type, 2	0.144	Yeast
si:ch211-244o22.2	si:ch211-244o22.2	0.144
csnk1da	casein kinase 1, delta a	0.143	Mouse Fly
senp3a	SUMO1/sentrin/SMT3 specific peptidase 3a	0.143
rlf	rearranged L-myc fusion	0.143
anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	0.143
pppde1	PPPDE peptidase domain containing 1	0.143
tph1b	tryptophan hydroxylase 1b	0.142
rnaset2	ribonuclease T2	0.141
eif4h	eukaryotic translation initiation factor 4h	0.141
xbp1	X-box binding protein 1	0.140
cdca8	cell division cycle associated 8	0.140
svil	supervillin	0.139
zgc:92139	zgc:92139	0.139
zgc:111944	zgc:111944	0.137
senp6a	SUMO1/sentrin specific peptidase 6a	0.136
kpna2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.135
ube2d2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.135	Yeast
pdlim4	PDZ and LIM domain 4	0.134
lin52	lin-52 homolog (C. elegans)	0.133
tfg	trk-fused gene	0.133
fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.131	Human Yeast
zgc:103471	zgc:103471	0.131
ilk	integrin linked kinase	0.131
arntl2	aryl hydrocarbon receptor nuclear translocator-like 2	0.127
hirip5	HIRA interacting protein 5	0.127
grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.126
wu:fd10h03	wu:fd10h03	0.126
copa	coatomer protein complex, subunit alpha	0.126
fam50a	family with sequence similarity 50, member A	0.125
cul3a	cullin 3a	0.124	Human Mouse
gna13a	guanine nucleotide binding protein (G protein), alpha 13a	0.124
arntl1a	aryl hydrocarbon receptor nuclear translocator-like 1a	0.124	Mouse
psmb11	proteasome (prosome, macropain) subunit, beta type, 11	0.123
napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.121
zgc:55347	zgc:55347	0.120
zgc:101121	zgc:101121	0.120
rab11ba	RAB11B, member RAS oncogene family, a	0.120
tlk2	tousled-like kinase 2	0.120	Human
akirin2	akirin 2	0.120
rnf40	ring finger protein 40	0.119
hug	HuG	0.119
usp14	ubiquitin specific protease 14 (tRNA-guanine transglycosylase)	0.119
pnrc2	proline-rich nuclear receptor coactivator 2	0.118
pbrm1l	polybromo 1, like	0.118
vapal	VAMP (vesicle-associated membrane protein)-associated protein A, like	0.117
prkrir	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	0.117
pgrmc2	progesterone receptor membrane component 2	0.116
eif3s10	eukaryotic translation initiation factor 3, subunit 10 (theta)	0.116
hspa8	heat shock protein 8	0.116
arf1l	ADP-ribosylation factor 1 like	0.115
prpf40a	PRP40 pre-mRNA processing factor 40 homolog A (yeast)	0.115
si:ch73-9j13.1	si:ch73-9j13.1	0.115
ciz1	CDKN1A interacting zinc finger protein 1	0.114
eif4g2a	eukaryotic translation initiation factor 4, gamma 2a	0.114
g2e3	G2/M-phase specific E3 ubiquitin ligase	0.114
fibp	fibroblast growth factor (acidic) intracellular binding protein	0.114
mxa	myxovirus (influenza) resistance A	0.113
nup93	nucleoporin 93	0.113
rxrbb	retinoid x receptor, beta b	0.112
ikbkg	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.112
caprin1a	cell cycle associated protein 1a	0.112
plekha3	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3	0.112
lman2	lectin, mannose-binding 2	0.112
flot1b	flotillin 1b	0.111
cul2	cullin 2	0.111	Worm
ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.111
LOC553527	hypothetical protein LOC553527	0.111
plaa	phospholipase A2-activating protein	0.111	Yeast
ctnnb2	catenin, beta 2	0.111
smad5	MAD homolog 5 (Drosophila)	0.110
abcb3l1	ATP-binding cassette, sub-family B (MDR/TAP), member 3 like 1	0.110
zgc:55582	zgc:55582	0.110
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.110
tnpo3	transportin 3	0.110
usp25	ubiquitin specific protease 25	0.109
xirp1	xin actin-binding repeat containing 1	0.109
glrx3	glutaredoxin 3	0.108
klhdc10	kelch domain containing 10	0.107
crip2	cysteine-rich protein 2	0.107
tceb1b	transcription elongation factor B (SIII), polypeptide 1b	0.107
ctnnb1	catenin (cadherin-associated protein), beta 1	0.107
gabbr1a	gamma-aminobutyric acid (GABA) B receptor, 1a	0.107
sestd1	SEC14 and spectrin domains 1	0.106
rangap1	Ran GTPase activating protein 1	0.106
ncl1	nicalin	0.106
eif1axb	eukaryotic translation initiation factor 1A, X-linked, b	0.105
tax1bp1b	Tax1 (human T-cell leukemia virus type I) binding protein 1b	0.105
ccne	cyclin E	0.104	Fly
yy1a	YY1 transcription factor a	0.104
tbc1d23	TBC1 domain family, member 23	0.104
sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.104	Human
vdra	vitamin D receptor a	0.104
bag6	BCL2-associated athanogene 6	0.103
pbx2	pre-B-cell leukemia transcription factor 2	0.103
foxo3b	forkhead box O3b	0.103
rtn4a	reticulon 4a	0.103
sas	sarcoma amplified sequence	0.103
chic2	cysteine-rich hydrophobic domain 2	0.103
hnrpkl	heterogeneous nuclear ribonucleoprotein K, like	0.102
tpd52l2a	tumor protein D52-like 2a	0.102
ube2q2	ubiquitin-conjugating enzyme E2Q family member 2	0.102
rag1	recombination activating gene 1	0.102
gadd45bb	growth arrest and DNA-damage-inducible, beta b	0.102
ciao1	cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae)	0.101
hgs	hepatocyte growth factor-regulated tyrosine kinase substrate	0.101
b4galt6	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6	0.101
wnt10a	wingless-type MMTV integration site family, member 10a	0.101
tmem50a	transmembrane protein 50A	0.100
cpsf3l	cleavage and polyadenylation specific factor 3-like	0.100
xrn1	5'-3' exoribonuclease 1	0.100
abcf1	ATP-binding cassette, sub-family F (GCN20), member 1	0.100
zgc:55886	zgc:55886	0.100
prc1a	protein regulator of cytokinesis 1a	0.100
wwp1	WW domain containing E3 ubiquitin protein ligase 1	0.100
rtkn2	rhotekin 2	0.099
syap1	synapse associated protein 1	0.099
psme2	proteasome activator subunit 2	0.099
zgc:56706	zgc:56706	0.099
arntl1b	aryl hydrocarbon receptor nuclear translocator-like 1b	0.098	Mouse
ncaph	non-SMC condensin I complex, subunit H	0.098
med24	mediator complex subunit 24	0.097
ythdf3	YTH domain family 3	0.097
safb	scaffold attachment factor B	0.097
gps1	G protein pathway suppressor 1	0.097
fxr2	fragile X mental retardation, autosomal homolog 2	0.097
ggnbp2	gametogenetin binding protein 2	0.097
b3gat3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) and beta3-glucuronyltransferase	0.097
zgc:77817	zgc:77817	0.097
spast	spastin	0.096
ncoa2	nuclear receptor coactivator 2	0.096
zgc:55683	zgc:55683	0.096
wu:fb80e01	wu:fb80e01	0.096
fbxw2	F-box and WD repeat domain containing 2	0.096
zgc:110113	zgc:110113	0.095
hn1l	hematological and neurological expressed 1-like	0.095
pdcd10b	programmed cell death 10b	0.095
zfand5b	zinc finger, AN1-type domain 5b	0.095
rp42-pen	rp42 homolog (pending) and rp42 homolog	0.095
atg13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.095
arpc2	actin related protein 2/3 complex, subunit 2	0.095
acvr1b	activin A receptor, type IB	0.094
akt2	v-akt murine thymoma viral oncogene homolog 2	0.093
mbd3a	methyl-CpG binding domain protein 3a	0.093
rsrc2	arginine/serine-rich coiled-coil 2	0.093
dtl	denticleless homolog (Drosophila)	0.092	Human
maf1	MAF1 homolog (S. cerevisiae)	0.091
tm9sf2	transmembrane 9 superfamily member 2	0.091
zgc:73265	zgc:73265	0.091
si:rp71-45k5.4	si:rp71-45k5.4	0.091
pdcd10a	programmed cell death 10a	0.091
mkln1	muskelin 1, intracellular mediator containing kelch motifs	0.090
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.090
taldo1	transaldolase 1	0.090
cry1a	cryptochrome 1a	0.090
ywhaqa	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a	0.090
ttc35	tetratricopeptide repeat domain 35	0.090
tie2	endothelium-specific receptor tyrosine kinase 2	0.090
sept8a	septin 8a	0.090
erh	enhancer of rudimentary homolog (Drosophila)	0.089
dcst1	DC-STAMP domain containing 1	0.089
zgc:73100	zgc:73100	0.089
ankrd13c	ankyrin repeat domain 13C	0.089
naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	0.089
pop7	processing of precursor 7, ribonuclease P family	0.088
golga5	golgi autoantigen, golgin subfamily a, 5	0.088
yipf5	Yip1 domain family, member 5	0.088
cops4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.088	Fly
zfand5a	zinc finger, AN1-type domain 5a	0.088
ywhaqb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b	0.087
spag7	sperm associated antigen 7	0.086
lysmd3	LysM, putative peptidoglycan-binding, domain containing 3	0.086
cnnm2a	cyclin M2a	0.086
fshr	follicle stimulating hormone receptor	0.086
papolg	poly(A) polymerase gamma	0.086
sec23ip	SEC23 interacting protein	0.086
polb	polymerase (DNA directed), beta	0.086
si:ch211-51m24.3	si:ch211-51m24.3	0.085
arfgef1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.085
prp19	PRP19/PSO4 homolog (S. cerevisiae)	0.085
pcdh10b	protocadherin 10b	0.085
zgc:85866	zgc:85866	0.085
glulb	glutamate-ammonia ligase (glutamine synthase) b	0.085
wnt3	wingless-type MMTV integration site family, member 3	0.085
snx27	sorting nexin family member 27	0.084
zgc:77849	zgc:77849	0.084
ppp1caa	protein phosphatase 1, catalytic subunit, alpha isoform a	0.084
yipf3	Yip1 domain family, member 3	0.084
cul1b	cullin 1b	0.084	Human Mouse
racgap1	Rac GTPase-activating protein 1	0.084
exoc1	exocyst complex component 1	0.083
rbm4.2	RNA binding motif protein 4.2	0.083
zgc:100787	zgc:100787	0.083
zgc:55813	zgc:55813	0.083
zgc:55876	zgc:55876	0.083
zgc:56525	zgc:56525	0.083
acp5b	acid phosphatase 5b, tartrate resistant	0.082
pou2f1a	POU class 2 homeobox 1a	0.081
tfpi2	tissue factor pathway inhibitor 2	0.081
fbxw11b	F-box and WD-40 domain protein 11b	0.081	Human Mouse
wdr45l	wdr45 like	0.081
cdk8	cyclin-dependent kinase 8	0.081
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.081
ctdnep1a	CTD nuclear envelope phosphatase 1a	0.081
nktr	natural killer-tumor recognition sequence	0.081
wrb	tryptophan rich basic protein	0.081
akap8l	A kinase (PRKA) anchor protein 8-like	0.081
sdcbp	syndecan binding protein (syntenin)	0.081
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.080	Human
dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.080
tmem199	transmembrane protein 199	0.080
ythdf1	YTH domain family, member 1	0.080
crygm4	crystallin, gamma M4	0.079
smek1	SMEK homolog 1, suppressor of mek1 (Dictyostelium)	0.079
ckap5	cytoskeleton associated protein 5	0.079
tial1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.079
ptbp1a	polypyrimidine tract binding protein 1a	0.079
parn	poly(A)-specific ribonuclease (deadenylation nuclease)	0.079
msto1	misato homolog 1 (Drosophila)	0.078
mtmr8	myotubularin related protein 8	0.078
eif5a2	eukaryotic translation initiation factor 5A2	0.078
entpd4	ectonucleoside triphosphate diphosphohydrolase 4	0.078
zgc:55573	zgc:55573	0.078
fkbp1aa	FK506 binding protein 1Aa	0.078
psmb8	proteasome (prosome, macropain) subunit, beta type, 8	0.077
myef2	myelin expression factor 2	0.077
hmgb1a	high-mobility group box 1a	0.077
dip2ba	DIP2 disco-interacting protein 2 homolog Ba (Drosophila)	0.077
mknk1	MAP kinase interacting serine/threonine kinase 1	0.077
rplp0	ribosomal protein, large, P0	0.077
zgc:162965	zgc:162965	0.077
rbmx	RNA binding motif protein, X-linked	0.076
kdm5c	lysine (K)-specific demethylase 5C	0.076
wu:fc61g08	wu:fc61g08	0.076
med27	mediator complex subunit 27	0.076
acat1	acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)	0.076
ube2l3b	ubiquitin-conjugating enzyme E2L 3b	0.076	Mouse
rae1	RAE1 RNA export 1 homolog (S. pombe)	0.076
unc5b	unc-5 homolog B (C. elegans)	0.076
zgc:66100	zgc:66100	0.076
acvrl1	activin A receptor type II-like 1	0.076
dynlrb1	dynein, light chain, roadblock-type 1	0.076
ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.075
pik3r4	phosphoinositide-3-kinase, regulatory subunit 4	0.075
map3k4	mitogen activated protein kinase kinase kinase 4	0.075
yipf4	Yip1 domain family, member 4	0.075
ccnt2a	cyclin T2a	0.075
pkp2	plakophilin 2	0.075
polr2b	polymerase (RNA) II (DNA directed) polypeptide B	0.075
gopc	golgi associated PDZ and coiled-coil motif containing	0.075
kpna3	karyopherin (importin) alpha 3	0.075
mylipa	myosin regulatory light chain interacting protein a	0.074
runx2a	runt-related transcription factor 2a	0.074
h3f3d	H3 histone, family 3D	0.074
cops3	COP9 constitutive photomorphogenic homolog subunit 3	0.074
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.074
sec24c	SEC24 family, member C (S. cerevisiae)	0.074
si:ch211-160j6.2	si:ch211-160j6.2	0.074
fgfrl1a	fibroblast growth factor receptor-like 1a	0.074
itm2ba	integral membrane protein 2Ba	0.074
kif11	kinesin family member 11	0.074
htr1aa	5-hydroxytryptamine (serotonin) receptor 1A a	0.074
kcmf1	potassium channel modulatory factor 1	0.073
hist2h2l	histone 2, H2, like	0.073
tram1	translocating chain-associating membrane protein 1	0.073
kdm6al	lysine (K)-specific demethylase 6A, like	0.073
clpp	ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)	0.073
pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.073
tp53bp2	tumor protein p53 binding protein, 2	0.073
trim55a	tripartite motif-containing 55a	0.073
stat5.1	signal transducer and activator of transcription 5.1	0.073
ncapg	non-SMC condensin I complex, subunit G	0.073
cflar	CASP8 and FADD-like apoptosis regulator	0.073
acbd3	acyl-Coenzyme A binding domain containing 3	0.073
apaf1	apoptotic protease activating factor 1	0.073
nutf2	nuclear transport factor 2	0.073
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.073
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.073
ctsd	cathepsin D	0.073
srp19	signal recognition particle 19	0.072
wnt5a	wingless-type MMTV integration site family, member 5a	0.072
exoc7	exocyst complex component 7	0.072
jhdm1da	jumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae)	0.072
ergic2	ERGIC and golgi 2	0.072
si:ch211-191i18.1	si:ch211-191i18.1	0.072
wdr33	WD repeat domain 33	0.072
smarce1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.072
zgc:101577	zgc:101577	0.072
vps24	vacuolar protein sorting 24 homolog (S. cerevisiae)	0.072
oaz2a	ornithine decarboxylase antizyme 2a	0.071
thap11	THAP domain containing 11	0.071
derl1	Der1-like domain family, member 1	0.071	Human
hic1l	hypermethylated in cancer 1 like	0.071
ran	ras-related nuclear protein	0.071
casp8	caspase 8, apoptosis-related cysteine peptidase	0.071
abhd4	abhydrolase domain containing 4	0.071
slc8a4b	solute carrier family 8 (sodium/calcium exchanger), member 4b	0.071
zgc:111821	zgc:111821	0.071
tmem38a	transmembrane protein 38A	0.071
herpud1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.070
glcea	glucuronyl C5-epimerase a	0.070
psmg1	proteasome (prosome, macropain) assembly chaperone 1	0.070
map2k4b	mitogen-activated protein kinase kinase 4b	0.070
zgc:113019	zgc:113019	0.070
vps39	vacuolar protein sorting 39 homolog (S. cerevisiae)	0.070
alp	alkaline phosphatase	0.070
cstf1	cleavage stimulation factor, 3' pre-RNA, subunit 1	0.070
wu:fa27a01	wu:fa27a01	0.070
cnot3a	CCR4-NOT transcription complex, subunit 3a	0.069
hs6st2	heparan sulfate 6-O-sulfotransferase 2	0.069
psenen	presenilin enhancer 2 homolog	0.069
ccdc6a	coiled-coil domain containing 6a	0.069
slc48a1b	solute carrier family 48 (heme transporter), member 1b	0.069
taf11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.069
ppig	peptidyl-prolyl isomerase G (cyclophilin G)	0.069
trappc5	trafficking protein particle complex 5	0.069
sox8	SRY-box containing gene 8	0.069
iah1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)	0.069
tia1	cytotoxic granule-associated RNA binding protein 1	0.069
aldoaa	aldolase a, fructose-bisphosphate, a	0.069
tmem93	transmembrane protein 93	0.069
det1	de-etiolated homolog 1 (Arabidopsis)	0.069
tmem11	transmembrane protein 11	0.069
pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	0.069
zgc:103671	zgc:103671	0.068
LOC100004941	grpE protein homolog 2, mitochondrial-like	0.068
stk35l	serine/threonine kinase 35, like	0.068
vps28	vacuolar protein sorting 28 (yeast)	0.068	Human Fly
arih2	ariadne homolog 2 (Drosophila)	0.068	Human
atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.068
ppp2r5eb	protein phosphatase 2, regulatory subunit B', epsilon isoform b	0.068
zgc:153369	zgc:153369	0.068
ncapd2	non-SMC condensin I complex, subunit D2	0.068
aup1	ancient ubiquitous protein 1	0.068
tuba8l	tubulin, alpha 8 like	0.068
pald	paladin	0.067
cdc37l1	CDC37 cell division cycle 37 homolog (S. cerevisiae)-like 1	0.067
plekhf2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.067
nuf2	NUF2, NDC80 kinetochore complex component, homolog	0.067
zgc:92765	zgc:92765	0.067
vps52	vacuolar protein sorting 52 (yeast)	0.067
a1cf	apobec1 complementation factor	0.067
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.067
srpk1a	serine/arginine-rich protein specific kinase 1a	0.067
ext1c	exostoses (multiple) 1c	0.067
arf1	ADP-ribosylation factor 1	0.067
ppp1r10	protein phosphatase 1, regulatory subunit 10	0.067
atl2	atlastin GTPase 2	0.067
serpinb1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.067
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.067
dda1	DET1 and DDB1 associated 1	0.067
clock	clock	0.066	Mouse
large	like-glycosyltransferase	0.066
ube2i2	ubiquitin-conjugating enzyme E2I2	0.066	Rat
zranb1b	zinc finger, RAN-binding domain containing 1b	0.066
rabac1	Rab acceptor 1 (prenylated)	0.066
scamp2	secretory carrier membrane protein 2	0.066
eif5a	eukaryotic translation initiation factor 5A	0.066
fem1c	fem-1 homolog c (C.elegans)	0.066
zgc:85882	zgc:85882	0.066
nudt5	nudix (nucleoside diphosphate linked moiety X)-type motif 5	0.066
ccdc94	coiled-coil domain containing 94	0.065
smc2	structural maintenance of chromosomes 2	0.065
bactin2	bactin2	0.065
gas6	growth arrest-specific 6	0.065
atp6v0b	ATPase, H+ transporting, V0 subunit B	0.065
vasp	vasodilator-stimulated phosphoprotein	0.065
ergic3	ERGIC and golgi 3	0.065
sec61al1	Sec61 alpha like 1	0.065
ext2	exostoses (multiple) 2	0.065
hs2st1a	heparan sulfate 2-O-sulfotransferase 1a	0.065
prc1b	protein regulator of cytokinesis 1b	0.064
stat1b	signal transducer and activator of transcription 1b	0.064
phf17	PHD finger protein 17	0.064
cd74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.064
zgc:112077	zgc:112077	0.064	Human Yeast Mouse
praf2	PRA1 domain family, member 2	0.064
zgc:103670	zgc:103670	0.064
ube2v2	ubiquitin-conjugating enzyme E2 variant 2	0.064	Rat
LOC100536090	targeting protein for Xklp2-B-like	0.064
khdrbs1b	KH domain containing, RNA binding, signal transduction associated 1b	0.064
plk2b	polo-like kinase 2b (Drosophila)	0.064
zgc:103440	zgc:103440	0.064	Human
ndel1b	nudE nuclear distribution gene E homolog like 1 (A. nidulans) B	0.064
cdc42se1	CDC42 small effector 1	0.064
guca1b	guanylate cyclase activator 1B	0.064
cse1l	chromosome segregation 1-like (S. cerevisiae)	0.063
stard3	START domain containing 3	0.063
eif4e	eukaryotic translation initiation factor 4e	0.063
pdia4	protein disulfide isomerase associated 4	0.063
sf3b14	splicing factor 3B	0.063
ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.063
zgc:56304	zgc:56304	0.063
egr2b	early growth response 2b	0.062
znf207a	zinc finger protein 207, a	0.062	Human
sb:cb429	sb:cb429	0.062
yy1b	YY1 transcription factor b	0.062
clptm1	cleft lip and palate associated transmembrane protein 1	0.062
gadd45aa	growth arrest and DNA-damage-inducible, alpha, a	0.062
tmem170a	transmembrane protein 170A	0.062
pdgfb	platelet derived growth factor, B polypeptide	0.062
slc12a9	solute carrier family 12 (potassium/chloride transporters), member 9	0.062
si:dkey-177p2.3	si:dkey-177p2.3	0.062
zgc:64051	zgc:64051	0.062
ppp6c	protein phosphatase 6, catalytic subunit	0.062
agtr2	angiotensin II receptor, type 2	0.062
drap1	DR1-associated protein 1 (negative cofactor 2 alpha)	0.062
helb	helicase (DNA) B	0.062
march5l	membrane-associated ring finger (C3HC4) 5, like	0.062
zgc:56112	zgc:56112	0.062
gmnn	geminin, DNA replication inhibitor	0.061
zgc:92303	zgc:92303	0.061
rabgef1	RAB guanine nucleotide exchange factor (GEF) 1	0.061
supt6h	suppressor of Ty 6 homolog	0.061
sox11a	SRY-box containing gene 11a	0.061
mapk14a	mitogen-activated protein kinase 14a	0.061
zgc:66447	zgc:66447	0.061
unc50	unc-50 homolog (C. elegans)	0.061
hectd3	HECT domain containing 3	0.061
ppp2r5d	protein phosphatase 2, regulatory subunit B', delta	0.061
zgc:92715	zgc:92715	0.061
nedd8	neural precursor cell expressed, developmentally down-regulated 8	0.060
pitpnb	phosphotidylinositol transfer protein, beta	0.060
ap1g1	adaptor-related protein complex 1, gamma 1 subunit	0.060
tob1a	transducer of ERBB2, 1a	0.060
si:dkeyp-110c7.1	si:dkeyp-110c7.1	0.060
maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)	0.060
si:dkey-46a10.3	si:dkey-46a10.3	0.060
zgc:56049	zgc:56049	0.060
slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.060
zgc:77155	zgc:77155	0.060
pi4kb	phosphatidylinositol 4-kinase, catalytic, beta	0.060
ros1	v-ros UR2 sarcoma virus oncogene homolog 1 (avian)	0.060
dopey2	dopey family member 2	0.060
zgc:64177	zgc:64177	0.060
slc26a5	solute carrier family 26, member 5	0.060
arl8ba	ADP-ribosylation factor-like 8Ba	0.060
ube2q1	ubiquitin-conjugating enzyme E2Q (putative) 1	0.059
phf10	PHD finger protein 10	0.059
eif2ak3	eukaryotic translation initiation factor 2-alpha kinase 3	0.059
cdc42	cell division cycle 42	0.059
gtf2b	general transcription factor IIB	0.059
zgc:91931	zgc:91931	0.059
ppp2r5ea	protein phosphatase 2, regulatory subunit B', epsilon isoform a	0.059
nf1b	neurofibromin 1b	0.059
pfn2l	profilin 2 like	0.059
ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.059
aktip	akt interacting protein	0.059
creg2	cellular repressor of E1A-stimulated genes 2	0.059
usp4	ubiquitin specific protease 4 (proto-oncogene)	0.059
adra2c	adrenergic, alpha-2C-, receptor	0.059
ptp4a1	protein tyrosine phosphatase type IVA, member 1	0.058
zgc:136773	zgc:136773	0.058
ftsjd1	FtsJ methyltransferase domain containing 1	0.058
tbc1d16	TBC1 domain family, member 16	0.058
hspa5	heat shock protein 5	0.058	Yeast
hspb8	heat shock protein, alpha-crystallin-related, b8	0.058
si:dkey-15j16.2	si:dkey-15j16.2	0.058
zgc:77056	zgc:77056	0.058
cpeb4	cytoplasmic polyadenylation element binding protein 4	0.058
ihha	Indian hedgehog homolog a	0.058
gtpbp1l	GTP binding protein 1, like	0.058
zgc:112257	zgc:112257	0.058
LOC100537975	thyroid receptor-interacting protein 11-like	0.058
inhbb	inhibin, beta B	0.058
cyt1	type I cytokeratin, enveloping layer	0.058
pomt2	protein-O-mannosyltransferase 2	0.058
zgc:175140	zgc:175140	0.058
ntf7	neurotrophin 7	0.058
zc3h10	zinc finger CCCH-type containing 10	0.058
dbt	dihydrolipoamide branched chain transacylase E2	0.058
wnt8b	wingless-type MMTV integration site family, member 8b	0.058
chrnb3a	cholinergic receptor, nicotinic, beta polypeptide 3a	0.057
orc6	origin recognition complex, subunit 6	0.057
sart1	squamous cell carcinoma antigen recognised by T cells	0.057
prox2	prospero homeobox 2	0.057
h1m	linker histone H1M	0.057
pcdh8	protocadherin 8	0.057
zgc:77262	zgc:77262	0.057
tra2a	transformer-2 alpha	0.057
gnrhr3	gonadotropin releasing hormone receptor 3	0.057
asna1	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)	0.057
calrl	calreticulin like	0.057
ankha	ankylosis, progressive homolog a	0.057
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.057
crebbpb	CREB binding protein b	0.057
mecp2	methyl CpG binding protein 2	0.057
mpp6b	membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)	0.057
lonp2	lon peptidase 2, peroxisomal	0.057
rilpl2	Rab interacting lysosomal protein-like 2	0.057
smad2	MAD homolog 2 (Drosophila)	0.057
gatsl2	GATS protein-like 2	0.056
fxr1	fragile X mental retardation, autosomal homolog 1	0.056
e4f1	E4F transcription factor 1	0.056
cnpy1	canopy1	0.056
map2k7	mitogen-activated protein kinase kinase 7	0.056
si:ch1073-210b3.1	si:ch1073-210b3.1	0.056
slc35b2	solute carrier family 35, member B2	0.056
plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.056
rpgr	retinitis pigmentosa GTPase regulator protein 1	0.056
zgc:113518	zgc:113518	0.056
bmp8a	bone morphogenetic protein 8a	0.056
psme1	proteasome activator subunit 1	0.056
llgl2	lethal giant larvae homolog 2 (Drosophila)	0.056
piga	phosphatidylinositol glycan anchor biosynthesis, class A	0.056
atp13a2	ATPase type 13A2	0.056
zgc:114169	zgc:114169	0.056
zgc:152900	zgc:152900	0.056
slc17a9b	solute carrier family 17, member 9b	0.056
aldocb	aldolase C, fructose-bisphosphate, b	0.056
sept7b	septin 7b	0.056
atxn7l2b	ataxin 7-like 2b	0.056
zgc:66415	zgc:66415	0.056
zc3h14	zinc finger CCCH-type containing 14	0.056
mc5rb	melanocortin 5b receptor	0.055
zgc:63962	zgc:63962	0.055
zgc:92321	zgc:92321	0.055
gosr1	golgi SNAP receptor complex member 1	0.055
si:ch211-124k10.2	si:ch211-124k10.2	0.055
zgc:112425	zgc:112425	0.055
fbxl14b	F-box and leucine-rich repeat protein 14b	0.055
hmcn1	hemicentin 1	0.055
timp2b	tissue inhibitor of metalloproteinase 2b	0.055
vps36	vacuolar protein sorting 36 homolog (S. cerevisiae)	0.055
scnm1	sodium channel modifier 1	0.055
myst2	MYST histone acetyltransferase 2	0.055
clk4a	CDC-like kinase 4a	0.055
kdsr	3-ketodihydrosphingosine reductase	0.055
chrnb3b	cholinergic receptor, nicotinic, beta polypeptide 3b	0.055
zgc:85812	zgc:85812	0.055
stt3b	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)	0.054	Human
srp54	signal recognition particle 54	0.054
neurog1	neurogenin 1	0.054
zgc:64133	zgc:64133	0.054
zgc:110468	zgc:110468	0.054
zgc:103580	zgc:103580	0.054
patl1	protein associated with topoisomerase II homolog 1 (yeast)	0.054
bon	bonnie and clyde	0.054
LOC555713	hypothetical LOC555713	0.054
eda	ectodysplasin A	0.054
si:dkeyp-50f5.1	si:dkeyp-50f5.1	0.054
cnppd1	cyclin Pas1/PHO80 domain containing 1	0.054
myst3	MYST histone acetyltransferase (monocytic leukemia) 3	0.054
lamp2	lysosomal membrane glycoprotein 2	0.054
ppm1d	protein phosphatase 1D magnesium-dependent, delta isoform	0.054
morc2	MORC family CW-type zinc finger 2	0.054
zgc:110298	zgc:110298	0.054
oaz1	ornithine decarboxylase antizyme 1	0.053
tuba8l4	tubulin, alpha 8 like 4	0.053
plod2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.053
sb:cb134	sb:cb134	0.053
zgc:101659	zgc:101659	0.053
u2af2b	U2 small nuclear RNA auxiliary factor 2b	0.053
LOC100331628	tumor necrosis factor ligand superfamily member 11-like	0.053
gtf2h2	general transcription factor IIH, polypeptide 2	0.053
zgc:64137	zgc:64137	0.053
tomm40	translocase of outer mitochondrial membrane 40 homolog (yeast)	0.053
mtpn	myotrophin	0.053
sra1	steroid receptor RNA activator 1	0.053
zgc:92287	zgc:92287	0.053
scd	stearoyl-CoA desaturase (delta-9-desaturase)	0.053
mlx	MAX-like protein X	0.053
tlr4bb	toll-like receptor 4b, duplicate b	0.053
zgc:110682	zgc:110682	0.053
zgc:158603	zgc:158603	0.053
tollip	toll interacting protein	0.053
pcbp2	poly(rC) binding protein 2	0.053	Human
st3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	0.053
mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.053
rab20	RAB20, member RAS oncogene family	0.053
fes	feline sarcoma oncogene	0.053
mhc1uba	major histocompatibility complex class I UBA gene	0.053
si:ch211-278b8.3	si:ch211-278b8.3	0.053
rgp1	RGP1 retrograde golgi transport homolog (S. cerevisiae)	0.053
snw1	SNW domain containing 1	0.053
flt4	fms-related tyrosine kinase 4	0.053
vsg1	vessel-specific 1	0.052
sec63	SEC63-like (S. cerevisiae)	0.052
plxnb2a	plexin b2a	0.052
psen2	presenilin 2	0.052	Mouse
pgam2	phosphoglycerate mutase 2 (muscle)	0.052
eif4e1b	eukaryotic translation initiation factor 4e 1b	0.052
srm	spermidine synthase	0.052
atl3	atlastin 3	0.052
jmjd6	jumonji domain containing 6	0.052
ror2	receptor tyrosine kinase-like orphan receptor 2	0.052
flt1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.052
arid4a	AT rich interactive domain 4A (RBP1-like)	0.052
zgc:112211	zgc:112211	0.052
mmp14b	matrix metalloproteinase 14b (membrane-inserted)	0.052
rab8a	RAB8A, member RAS oncogene family	0.052
ahrrb	aryl-hydrocarbon receptor repressor b	0.052
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.052
ap4b1l	adaptor-related protein complex 4, beta 1 subunit-like	0.052