IMP: Integrative Multi-species Prediction

Danio rerio

11 genes annotated in zebrafish

Multi-species View

atrioventricular valve development

GO:0003171

The progression of the atrioventricular valve over time, from its formation to the mature structure.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "atrioventricular valve development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "atrioventricular valve development" (in gray)

Name	Description	Probability	Func Analog Organism
tbx20	T-box 20	0.705	Zebrafish Mouse
tbx5a	T-box 5a	0.670
runx1	runt-related transcription factor 1	0.610
bmp4	bone morphogenetic protein 4	0.595
nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.551
tbx16	T-box gene 16	0.529	Zebrafish
hnf1ba	HNF1 homeobox Ba	0.502
tal1	T-cell acute lymphocytic leukemia 1	0.501
gata6	GATA-binding protein 6	0.466
has2	hyaluronan synthase 2	0.440
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.415
fli1a	friend leukemia integration 1a	0.304
nkx2.5	NK2 transcription factor related 5	0.267
tbx2a	T-box gene 2a	0.249	Zebrafish
hand2	heart and neural crest derivatives expressed transcript 2	0.240
hhex	hematopoietically expressed homeobox	0.228
foxn4	forkhead box N4	0.223
vcana	versican a	0.221
nppa	natriuretic peptide precursor A	0.211
hspb7	heat shock protein family, alpha-crystallin-related, b7	0.201
fbln1	fibulin 1	0.175
klf2a	Kruppel-like factor 2a	0.171
notch1b	notch homolog 1b	0.138	Human Mouse
cdh2	cadherin 2, neuronal	0.129
gata5	GATA-binding protein 5	0.106	Zebrafish
hspb12	heat shock protein, alpha-crystallin-related, b12	0.104
dlc	deltaC	0.095
myl7	myosin, light polypeptide 7, regulatory	0.091
crip2	cysteine-rich protein 2	0.090
tbx1	T-box 1	0.089	Zebrafish
znfl2a	zinc finger-like gene 2a	0.084
lft1	lefty1	0.082
ptch1	patched 1	0.080
rhoua	ras homolog gene family, member Ua	0.075
gsna	gelsolin a	0.072
shha	sonic hedgehog a	0.071
lamb1a	laminin, beta 1a	0.068
tpm4	tropomyosin 4	0.067
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.063
lft2	lefty2	0.062
drl	draculin	0.055
lmo2	LIM domain only 2 (rhombotin-like 1)	0.054
lhx1a	LIM homeobox 1a	0.053
fn1	fibronectin 1	0.053
ntla	no tail a	0.050	Zebrafish
tbx18	T-box 18	0.050	Zebrafish
myod1	myogenic differentiation 1	0.047
mib	mind bomb	0.047
hspb1	heat shock protein, alpha-crystallin-related, 1	0.047
snai1a	snail homolog 1a (Drosophila)	0.046
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.044	Mouse
tnni1b	troponin I, skeletal, slow b	0.042
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.041
dld	deltaD	0.041
prdm1a	PR domain containing 1a, with ZNF domain	0.040
wnt11	wingless-type MMTV integration site family, member 11	0.040
fzd10	frizzled homolog 10	0.040
notch3	notch homolog 3	0.039
gja3	gap junction protein, alpha 3	0.038
hoxb1b	homeo box B1b	0.038
foxg1a	forkhead box G1a	0.035
wnt11r	wingless-type MMTV integration site family, member 11, related	0.035
tbx5b	T-box 5b	0.035
ndr2	nodal-related 2	0.034
slc8a1a	solute carrier family 8 (sodium/calcium exchanger), member 1a	0.033
oep	one-eyed pinhead	0.032
bmp2a	bone morphogenetic protein 2a	0.032	Mouse
pkd2	polycystic kidney disease 2	0.031
tbx2b	T-box 2b	0.030	Zebrafish
tfeb	transcription factor EB	0.029
tbx3	T-box 3	0.029	Zebrafish
fhla	four and a half LIM domains a	0.029
bmp2b	bone morphogenetic protein 2b	0.029	Mouse
irx3a	iroquois homeobox protein 3a	0.029
vsx1	visual system homeobox 1 homolog, chx10-like	0.029
klf4	Kruppel-like factor 4	0.029
her1	hairy-related 1	0.029
ywhai	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide	0.028
tgfb2	transforming growth factor, beta 2	0.028
osr2	odd-skipped related 2 (Drosophila)	0.028
fgf8a	fibroblast growth factor 8 a	0.027
hoxc8a	homeo box C8a	0.027
neo1	neogenin 1	0.027
mef2cb	myocyte enhancer factor 2cb	0.027
her7	hairy and enhancer of split related-7	0.027
tcf21	transcription factor 21	0.026
cyp26a1	cytochrome P450, subfamily XXVIA, polypeptide 1	0.025
slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.025
jag1b	jagged 1b	0.025
cdx4	caudal type homeo box transcription factor 4	0.024
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.023
tgfb3	transforming growth factor, beta 3	0.022
tbx24	T-box 24	0.022	Zebrafish
rbm24a	RNA binding motif protein 24a	0.022
tbx6	T-box gene 6	0.022	Zebrafish
apc	adenomatosis polyposis coli	0.021
alcama	activated leukocyte cell adhesion molecule a	0.021
gata2a	GATA-binding protein 2a	0.020
LOC566708	FL cytokine receptor-like	0.020
zgc:111821	zgc:111821	0.020
irx1a	iroquois homeobox protein 1, a	0.020
myf5	myogenic factor 5	0.020
smyd1b	SET and MYND domain containing 1b	0.020
foxa1	forkhead box A1	0.020
six4b	sine oculis homeobox homolog 4b	0.020
wnt5b	wingless-type MMTV integration site family, member 5b	0.019
yap1	Yes-associated protein 1	0.019
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.019
zic5	zic family member 5 (odd-paired homolog, Drosophila)	0.019
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.019
znf703	zinc finger protein 703	0.019
tfap2a	transcription factor AP-2 alpha	0.019
tp63	tumor protein p63	0.018
fgf17	fibroblast growth factor 17	0.018
hes6	hairy and enhancer of split 6 (Drosophila)	0.018
lmo4a	LIM domain only 4a	0.018
dcn	decorin	0.018
lama5	laminin, alpha 5	0.018
sox4a	SRY-box containing gene 4a	0.017	Mouse
aplnrb	apelin receptor b	0.017
cotl1	coactosin-like 1 (Dictyostelium)	0.017
wnt9a	wingless-type MMTV integration site family, member 9A	0.017
chd	chordin	0.017
hmgb1b	high-mobility group box 1b	0.017
foxi1	forkhead box I1	0.017
kdrl	kinase insert domain receptor like	0.017
foxe1	forkhead box E1 (thyroid transcription factor 2)	0.017
btg1	B-cell translocation gene 1	0.016
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.016
dlx6a	distal-less homeobox gene 6a	0.016
dusp6	dual specificity phosphatase 6	0.016
id1	inhibitor of DNA binding 1	0.016
eve1	even-skipped-like1	0.016
flot2a	flotillin 2a	0.016
spaw	southpaw	0.015
sox32	SRY-box containing gene 32	0.015
eif3hb	eukaryotic translation initiation factor 3, subunit H, b	0.015
pax2a	paired box gene 2a	0.015
perp	PERP, TP53 apoptosis effector	0.015
flh	floating head	0.014
gli2a	GLI-Kruppel family member GLI2a	0.014
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.014	Mouse
bactin1	bactin1	0.014
zfpm1	zinc finger protein, multitype 1	0.014	Mouse
ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.013
anxa11b	annexin A11b	0.013
ltbp3	latent transforming growth factor beta binding protein 3	0.013
foxj1a	forkhead box J1a	0.013
tmem88a	transmembrane protein 88 a	0.012
robo3	roundabout homolog 3	0.012
lypd6	LY6/PLAUR domain containing 6	0.012
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.012
gatsl2	GATS protein-like 2	0.012
krt4	keratin 4	0.012
foxa3	forkhead box A3	0.012
pdlim2	PDZ and LIM domain 2 (mystique)	0.012
fibin	fin bud initiation factor	0.012
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.012
unc45b	unc-45 homolog B (C. elegans)	0.012
her12	hairy-related 12	0.012
mef2ca	myocyte enhancer factor 2ca	0.011
satb2	SATB homeobox 2	0.011
pou3f2	POU class 3 homeobox 2	0.011
hoxa2b	homeo box A2b	0.011
pcdh8	protocadherin 8	0.011
ptgs1	prostaglandin-endoperoxide synthase 1	0.011
dlx2a	distal-less homeobox gene 2a	0.011
esr1	estrogen receptor 1	0.011
rgma	RGM domain family, member A	0.011
supt6h	suppressor of Ty 6 homolog	0.011
fgfrl1b	fibroblast growth factor receptor-like 1b	0.011
hoxd13a	homeo box D13a	0.011
pdcd4b	programmed cell death 4b	0.011
sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.011
dlb	deltaB	0.011
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.011
fgf4	fibroblast growth factor 4	0.011
epor	erythropoietin receptor	0.011
pycard	PYD and CARD domain containing	0.010
zgc:63523	zgc:63523	0.010
cfl1	cofilin 1 (non-muscle)	0.010
shhb	sonic hedgehog b	0.010
irf6	interferon regulatory factor 6	0.010
wls	wntless homolog (Drosophila)	0.010
gamt	guanidinoacetate N-methyltransferase	0.010
itga3b	integrin, alpha 3b	0.010
sp5l	Sp5 transcription factor-like	0.010
tob1a	transducer of ERBB2, 1a	0.010
col8a1a	collagen, type VIII, alpha 1a	0.010
insm1b	insulinoma-associated 1b	0.010
hoxa9a	homeo box A9a	0.010