IMP: Integrative Multi-species Prediction

Danio rerio

1 genes annotated in zebrafish

segment polarity determination

Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "segment polarity determination"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "segment polarity determination" (in gray)

Name	Description	Probability	Func Analog Organism
ptch2	patched 2	1.000
tbx1	T-box 1	0.991
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.991	Fly
fgf8a	fibroblast growth factor 8 a	0.949
shha	sonic hedgehog a	0.803	Fly
sox10	SRY-box containing gene 10	0.717
chd	chordin	0.712
foxd3	forkhead box D3	0.656
erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog	0.549	Fly
wnt5b	wingless-type MMTV integration site family, member 5b	0.540
smo	smoothened homolog (Drosophila)	0.530
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.418
ntla	no tail a	0.402
wu:fv91b12	wu:fv91b12	0.380
gli1	GLI-Kruppel family member 1	0.370	Fly
ptch1	patched 1	0.337
cdh2	cadherin 2, neuronal	0.321
tp53	tumor protein p53	0.288
dzip1	DAZ interacting protein 1	0.286
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.274
wnt8b	wingless-type MMTV integration site family, member 8b	0.268
gro2	groucho 2	0.259
flh	floating head	0.244
ndr2	nodal-related 2	0.231
csf1ra	colony stimulating factor 1 receptor, a	0.209
gli2a	GLI-Kruppel family member GLI2a	0.197	Fly
tbx16	T-box gene 16	0.193
lef1	lymphocyte enhancer binding factor 1	0.191
igf1rb	insulin-like growth factor 1b receptor	0.181
dusp6	dual specificity phosphatase 6	0.177
prdm5	PR domain containing 5	0.166
cdx4	caudal type homeo box transcription factor 4	0.163
col2a1a	collagen type II, alpha-1a	0.154
pax7a	paired box gene 7a	0.149
axin1	axin 1	0.144
ryk	receptor-like tyrosine kinase	0.138
mtp	microsomal triglyceride transfer protein	0.132
fancd2	Fanconi anemia, complementation group D2	0.130
dld	deltaD	0.127
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.127
fgfr3	fibroblast growth factor receptor 3	0.127
irx3a	iroquois homeobox protein 3a	0.125
cyp3a65	cytochrome P450, family 3, subfamily A, polypeptide 65	0.123
erbb3a	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a	0.122	Fly
mib	mind bomb	0.119
her5	hairy-related 5	0.114
sox9a	SRY-box containing gene 9a	0.112
wnt4a	wingless-type MMTV integration site family, member 4a	0.112
crestin	crestin	0.111
wnt11	wingless-type MMTV integration site family, member 11	0.107
egr2b	early growth response 2b	0.105
ihha	Indian hedgehog homolog a	0.098	Fly
sox19a	SRY-box containing gene 19a	0.094
pax2a	paired box gene 2a	0.094
wls	wntless homolog (Drosophila)	0.094	Fly
sox17	SRY-box containing gene 17	0.093
mitfa	microphthalmia-associated transcription factor a	0.092
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.091
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.089
gsc	goosecoid	0.088
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.085
zgc:158603	zgc:158603	0.084
oprm1	opioid receptor, mu 1	0.083
kita	kit receptor a	0.082
tll1	tolloid-like 1	0.080
eif2c4	eukaryotic translation initiation factor 2C, 4	0.077
hoxb1b	homeo box B1b	0.076
lrrc6	leucine rich repeat containing 6	0.075
fgf3	fibroblast growth factor 3	0.075
fgf4	fibroblast growth factor 4	0.068
sox32	SRY-box containing gene 32	0.066
LOC570775	protein argonaute-1-like	0.065
ntn1b	netrin 1b	0.061
sc:d812	sc:d812	0.060
gpr126	G protein-coupled receptor 126	0.060
htra1a	HtrA serine peptidase 1a	0.060
mmp2	matrix metalloproteinase 2	0.059
igf2a	insulin-like growth factor 2a	0.058
tm4sf4	transmembrane 4 L six family member 4	0.058
hnf1a	HNF1 homeobox a	0.055
aox3	aldehyde oxidase 3	0.054
tp73	tumor protein p73	0.053
ext2	exostoses (multiple) 2	0.050
smad5	MAD homolog 5 (Drosophila)	0.050
gro1	groucho 1	0.050
foxi1	forkhead box I1	0.048
hnf1ba	HNF1 homeobox Ba	0.047
vangl2	vang-like 2 (van gogh, Drosophila)	0.047
wnt3	wingless-type MMTV integration site family, member 3	0.046
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.046
card14	caspase recruitment domain family, member 14	0.045
scube2	signal peptide, CUB domain, EGF-like 2	0.045
irx3b	iroquois homeobox protein 3b	0.045
jag1b	jagged 1b	0.044
dab1a	disabled homolog 1a (Drosophila)	0.044
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.043
pparg	peroxisome proliferator activated receptor gamma	0.043
mstna	myostatin a	0.043
h1m	linker histone H1M	0.042
disp1	dispatched homolog 1 (Drosophila)	0.042
tuba8l3	tubulin, alpha 8 like 3	0.041
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.041
nrg1	neuregulin 1	0.040
LOC797832	similar to signal peptide, CUB domain, EGF-like 1	0.037
fzd5	frizzled homolog 5	0.037
foxa2	forkhead box A2	0.036
ptk6a	PTK6 protein tyrosine kinase 6a	0.036
pld1a	phospholipase D1a	0.035
dct	dopachrome tautomerase	0.035
myod1	myogenic differentiation 1	0.034
tbx24	T-box 24	0.034
appl1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.033
bactin1	bactin1	0.033
lrmp	lymphoid-restricted membrane protein	0.032
ror2	receptor tyrosine kinase-like orphan receptor 2	0.032
fabp2	fatty acid binding protein 2, intestinal	0.032
ep300b	E1A binding protein p300 b	0.032
f2rl1.1	coagulation factor II (thrombin) receptor-like 1.1	0.031
LOC555739	serine/threonine-protein kinase LMTK1-like	0.031
styk1	serine/threonine/tyrosine kinase 1	0.031
zbtb4	zinc finger and BTB domain containing 4	0.030
ltk	leukocyte tyrosine kinase	0.030
mga	MAX gene associated	0.030
nkx2.2a	NK2 transcription factor related 2a	0.030
sp2	sp2 transcription factor	0.029
fn1	fibronectin 1	0.028
sox9b	SRY-box containing gene 9b	0.028
rbl1	retinoblastoma-like 1 (p107)	0.028
has2	hyaluronan synthase 2	0.027
satb2	SATB homeobox 2	0.027
snai1b	snail homolog 1b (Drosophila)	0.027
col10a1	collagen, type X, alpha 1	0.027
spry2	sprouty homolog 2	0.027
slc39a6	solute carrier family 39 (zinc transporter), member 6	0.027
xylt1	xylosyltransferase 1	0.027
gpc4	glypican 4	0.026	Fly
si:dkeyp-7c9.1	si:dkeyp-7c9.1	0.026
ndr1	nodal-related 1	0.026
snai1a	snail homolog 1a (Drosophila)	0.025
pax3b	paired box gene 3b	0.025
her8a	hairy-related 8a	0.025
disc1	disrupted in schizophrenia 1	0.025
dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.024
slc39a3	solute carrier family 39 (zinc transporter), member 3	0.024
pnp4a	purine nucleoside phosphorylase 4a	0.024
csnk1a1	casein kinase 1, alpha 1	0.024
LOC557072	caspase recruitment domain-containing protein 11-like	0.023
rtf1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.023
si:ch211-241e15.2	si:ch211-241e15.2	0.023
npc1	Niemann-Pick disease, type C1	0.023
psen1	presenilin 1	0.023
k23	k23 gene	0.023
phox2a	paired-like homeobox 2a	0.023
runx2b	runt-related transcription factor 2b	0.022
abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.022
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.022
zgc:152984	zgc:152984	0.022
wnt10a	wingless-type MMTV integration site family, member 10a	0.022
pax3a	paired box gene 3a	0.022	Fly
sox19b	SRY-box containing gene 19b	0.022
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.022
pou5f1	POU domain, class 5, transcription factor 1	0.022
neurog1	neurogenin 1	0.021
alp	alkaline phosphatase	0.021
gdf6b	growth differentiation factor 6b	0.021
jub	jub, ajuba homolog (Xenopus laevis)	0.021
slc35b2	solute carrier family 35, member B2	0.021
dharma	dharma	0.020
cdkl1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.020
nog1	noggin 1	0.020
col8a1a	collagen, type VIII, alpha 1a	0.020
cdc16	cell division cycle 16 homolog (S. cerevisiae)	0.020
vent	ventral expressed homeobox	0.020
extl3	exostoses (multiple)-like 3	0.020
fas	Fas (TNF receptor superfamily, member 6)	0.019
nkx3.2	NK3 homeobox 2	0.019
clock	clock	0.019
egfra	epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	0.019	Fly
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.019
pkp2	plakophilin 2	0.019
ihhb	Indian hedgehog homolog b	0.019	Fly
wnt9b	wingless-type MMTV integration site family, member 9B	0.019
tyrp1b	tyrosinase-related protein 1b	0.019
tmprss4a	transmembrane protease, serine 4a	0.018
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.018
odz4	odd Oz/ten-m homolog 4	0.018
tmem147	transmembrane protein 147	0.018
sfrp5	secreted frizzled-related protein 5	0.018
ctnnd2a	catenin (cadherin-associated protein), delta 2a	0.018
snf8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.017
npnt	nephronectin	0.017
LOC796298	isotocin receptor-like 1	0.017
pcdh18b	protocadherin 18b	0.017
arl13b	ADP-ribosylation factor-like 13b	0.017
wnt5a	wingless-type MMTV integration site family, member 5a	0.017
dsg2	desmoglein 2	0.017
furina	furin (paired basic amino acid cleaving enzyme) a	0.017
ubr3	ubiquitin protein ligase E3 component n-recognin 3	0.017
nrp1b	neuropilin 1b	0.017
gle1	GLE1 RNA export mediator homolog (yeast)	0.017
ins	preproinsulin	0.017
gon4l	gon-4-like (C.elegans)	0.017
pigu	phosphatidylinositol glycan anchor biosynthesis, class U	0.017
arid4a	AT rich interactive domain 4A (RBP1-like)	0.017
syne2b	spectrin repeat containing, nuclear envelope 2b	0.017
ednrb1	endothelin receptor B	0.017
oep	one-eyed pinhead	0.017
rbm22	RNA binding motif protein 22	0.017
cdc42l	cell division cycle 42, like	0.017
rps6kal	ribosomal protein S6 kinase, like	0.016
gfpt1	glutamine-fructose-6-phosphate transaminase 1	0.016
appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	0.016
myo10l1	myosin X-like 1	0.016
chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.016
edn1	endothelin 1	0.016
nf1b	neurofibromin 1b	0.016
LOC567452	G protein-coupled receptor kinase 5-like	0.016
celsr1b	cadherin EGF LAG seven-pass G-type receptor 1b	0.016	Fly
nog3	noggin 3	0.016
th	tyrosine hydroxylase	0.016
supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	0.016
bon	bonnie and clyde	0.015
b4galt5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	0.015
ap1g1	adaptor-related protein complex 1, gamma 1 subunit	0.015
zgc:64161	zgc:64161	0.015
comta	catechol-O-methyltransferase a	0.015
tbx2b	T-box 2b	0.015
sec24d	SEC24 family, member D (S. cerevisiae)	0.015
slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	0.015
gng12a	guanine nucleotide binding protein (G protein), gamma 12a	0.015
zgc:171802	zgc:171802	0.015
men1	multiple endocrine neoplasia type 1 and multiple endocrine neoplasia I	0.015
csrnp1a	cysteine-serine-rich nuclear protein 1a	0.015
emx3	empty spiracles homeobox 3	0.015
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.015
nf1a	neurofibromin 1a	0.015
cnr1	cannabinoid receptor 1	0.015
hspb6	heat shock protein, alpha-crystallin-related, b6	0.015
atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.015
kbp	kif1-binding protein	0.015
mid1ip1a	MID1 interacting protein 1a	0.015
sec31b	Sec31 homolog B (S. cerevisiae)	0.015
antxr2a	anthrax toxin receptor 2a	0.015
hibadhb	3-hydroxyisobutyrate dehydrogenase b	0.015
pnrc2	proline-rich nuclear receptor coactivator 2	0.014
phf21a	PHD finger protein 21A	0.014
pdzrn3	PDZ domain containing RING finger 3 and PDZ domain containing ring finger 3	0.014
dbx1a	developing brain homeobox 1a	0.014
bglap	bone gamma-carboxyglutamate (gla) protein	0.014
gfer	growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)	0.014
col27a1b	collagen, type XXVII, alpha 1b	0.014
ripk2	receptor-interacting serine-threonine kinase 2	0.014
eve1	even-skipped-like1	0.014
pik3r2	phosphoinositide-3-kinase, regulatory subunit, polypeptide 2	0.014
cops6	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	0.014
zgc:77556	zgc:77556	0.014
si:ch211-240l19.8	si:ch211-240l19.8	0.014
has3	hyaluronan synthase 3	0.014
igf1	insulin-like growth factor 1	0.013
smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.013
pbx4	pre-B-cell leukemia transcription factor 4	0.013
meis2.1	myeloid ecotropic viral integration site 2.1	0.013
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.013
snx27	sorting nexin family member 27	0.013
irf2	interferon regulatory factor 2	0.013
tmem2	transmembrane protein 2	0.013
dla	deltaA	0.013
slc35c1	solute carrier family 35, member C1	0.013
stac3	SH3 and cysteine rich domain 3	0.013
taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto	0.013
wnt10b	wingless-type MMTV integration site family, member 10b	0.013
mical2a	microtubule associated monoxygenase, calponin and LIM domain containing 2a	0.013
mbp	myelin basic protein	0.013
gfra1a	gdnf family receptor alpha 1a	0.013
tyr	tyrosinase	0.013
sp5l	Sp5 transcription factor-like	0.013
si:dkey-21k24.2	si:dkey-21k24.2	0.013
met	met proto-oncogene (hepatocyte growth factor receptor)	0.012
map2k7	mitogen-activated protein kinase kinase 7	0.012
mtmr12	myotubularin related protein 12	0.012
mespb	mesoderm posterior b	0.012
srrm2	serine/arginine repetitive matrix 2	0.012
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.012
sec63	SEC63-like (S. cerevisiae)	0.012
nrxn3a	neurexin 3a	0.012
zgc:172101	zgc:172101	0.012
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.012
cdc73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.012
scd	stearoyl-CoA desaturase (delta-9-desaturase)	0.012
sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.012
sc:d173	sc:d173	0.012
hoxb2a	homeo box B2a	0.012
lamb2l	laminin, beta 2-like	0.012
elf2b	E74-like factor 2b (ets domain transcription factor)	0.012
ints6	integrator complex subunit 6	0.012
fancl	Fanconi anemia, complementation group L	0.012
ptk2.2	protein tyrosine kinase 2b	0.012
fmr1	fragile X mental retardation 1	0.012
usp24	ubiquitin specific peptidase 24	0.012
faslg	Fas ligand (TNF superfamily, member 6)	0.012
LOC557995	e3 ubiquitin-protein ligase RNF19A-like	0.012
unc45a	unc-45 homolog A (C. elegans)	0.012
ft1	alpha(1,3)fucosyltransferase gene 1	0.012
mbtps1	membrane-bound transcription factor protease, site 1	0.012
igiv1s5	immunoglobulin light iota variable 1, s5	0.011
igiv2s1	immunoglobulin light iota variable 2, s1	0.011
abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.011
myf5	myogenic factor 5	0.011
mkks	McKusick-Kaufman syndrome	0.011
ptpra	protein tyrosine phosphatase, receptor type, A	0.011
gga1	golgi associated, gamma adaptin ear containing, ARF binding protein 1	0.011
slc39a1	solute carrier family 39 (zinc transporter), member 1	0.011
tcf7l1b	transcription factor 7-like 1b (T-cell specific, HMG-box)	0.011
epn1	epsin 1	0.011
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.011
tshb	thyroid stimulating hormone, beta subunit	0.011
ndufb5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex 5	0.011
tfe3a	transcription factor binding to IGHM enhancer 3a	0.011
vps39	vacuolar protein sorting 39 homolog (S. cerevisiae)	0.011
clstn2	calsyntenin 2	0.011
zgc:171629	zgc:171629	0.011
pvrl1b	poliovirus receptor-related 1b	0.011
tsc22d3	TSC22 domain family, member 3	0.011
LOC100538030	sickle tail protein-like	0.011
sass6	spindle assembly 6 homolog (C. elegans)	0.011
znf574	zinc finger protein 574	0.011
ccdc151	coiled-coil domain containing 151	0.011
nos1	nitric oxide synthase 1 (neuronal)	0.011
si:dkey-175m17.8	si:dkey-175m17.8	0.011
wu:fk73b01	wu:fk73b01	0.011
admp	anti-dorsalizing morphogenic protein	0.011
myog	myogenin	0.011
bmp7a	bone morphogenetic protein 7a	0.011
zgc:85942	zgc:85942	0.011
mgp	matrix Gla protein	0.011
tfec	transcription factor EC	0.011
si:ch211-175f11.2	si:ch211-175f11.2	0.011
eda	ectodysplasin A	0.011
myh11a	myosin, heavy polypeptide 11, smooth muscle a	0.011
plekhg4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4	0.011
epas1a	endothelial PAS domain protein 1a	0.011
acana	aggrecan a	0.010
chchd1	coiled-coil-helix-coiled-coil-helix domain containing 1	0.010
si:dkeyp-104h9.6	si:dkeyp-104h9.6	0.010
sb:cb183	sb:cb183	0.010
cul1b	cullin 1b	0.010
LOC100537862	hypothetical protein LOC100537862	0.010
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.010
col4a2	collagen, type IV, alpha 2	0.010
kitlga	kit ligand a	0.010
si:rp71-39b20.7	si:rp71-39b20.7	0.010
cpb1	carboxypeptidase B1 (tissue)	0.010
rapsn	receptor-associated protein of the synapse, 43kD	0.010
LOC567405	novel protein similar to vertebrate megakaryocyte-associated tyrosine kinase (MATK)	0.010
myst3	MYST histone acetyltransferase (monocytic leukemia) 3	0.010
scamp2	secretory carrier membrane protein 2	0.010
cyp2aa11	cytochrome P450, family 2, subfamily AA, polypeptide 11	0.010
vasa	vasa homolog	0.010
rab34	RAB34, member RAS oncogene family	0.010
lmna	lamin A	0.010
igf1ra	insulin-like growth factor 1a receptor	0.010
fev	FEV (ETS oncogene family)	0.010