IMP
Process View
cellular response to toxic substance
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to toxic substance"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| hsp90b1 | heat shock protein 90, beta (grp94), member 1 | 0.565 | ||
| hsd3b1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 0.490 | ||
| hspd1 | heat shock 60kD protein 1 (chaperonin) | 0.177 | ||
| oprm1 | opioid receptor, mu 1 | 0.155 | ||
| cyp19a1b | cytochrome P450, family 19, subfamily A, polypeptide 1b | 0.137 | ||
| mef2ca | myocyte enhancer factor 2ca | 0.136 | Mouse | |
| th | tyrosine hydroxylase | 0.107 | ||
| mapk8b | mitogen-activated protein kinase 8b | 0.088 | ||
| oprk1 | opioid receptor, kappa 1 | 0.085 | ||
| sox9b | SRY-box containing gene 9b | 0.073 | ||
| slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.070 | ||
| igfbp1a | insulin-like growth factor binding protein 1a | 0.056 | ||
| igf3 | insulin-like growth factor 3 | 0.055 | ||
| foxh1 | forkhead box H1 | 0.054 | ||
| lgi1b | leucine-rich, glioma inactivated 1b | 0.053 | ||
| hint2 | histidine triad nucleotide binding protein 2 | 0.052 | ||
| srf | serum response factor | 0.049 | ||
| manf | mesencephalic astrocyte-derived neurotrophic factor | 0.048 | ||
| smyd1b | SET and MYND domain containing 1b | 0.046 | ||
| mef2cb | myocyte enhancer factor 2cb | 0.044 | Mouse | |
| plcb3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.043 | ||
| fshr | follicle stimulating hormone receptor | 0.042 | ||
| tac1 | tachykinin 1 | 0.041 | ||
| ikzf5 | IKAROS family zinc finger 5 | 0.040 | ||
| trpc1 | transient receptor potential cation channel, subfamily C, member 1 | 0.039 | ||
| tbx20 | T-box 20 | 0.035 | ||
| rag1 | recombination activating gene 1 | 0.034 | ||
| furina | furin (paired basic amino acid cleaving enzyme) a | 0.034 | ||
| star | steroidogenic acute regulatory protein | 0.034 | ||
| bmp15 | bone morphogenetic protein 15 | 0.032 | ||
| prox1 | prospero-related homeobox gene 1 | 0.031 | ||
| plxnb2a | plexin b2a | 0.031 | ||
| cyp19a1a | cytochrome P450, family 19, subfamily A, polypeptide 1a | 0.031 | ||
| chrna1 | cholinergic receptor, nicotinic, alpha polypeptide 1 | 0.029 | ||
| ef1a | elongation factor 1-alpha | 0.029 | ||
| s1pr2 | sphingosine-1-phosphate receptor 2 | 0.028 | ||
| mpp5a | membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a) | 0.028 | ||
| mstna | myostatin a | 0.028 | ||
| si:ch211-89f7.4 | si:ch211-89f7.4 | 0.026 | ||
| spi1 | spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 0.025 | ||
| cnr1 | cannabinoid receptor 1 | 0.025 | ||
| paqr7b | progestin and adipoQ receptor family member VII, b | 0.025 | ||
| mych | myelocytomatosis oncogene homolog | 0.024 | ||
| mapk14a | mitogen-activated protein kinase 14a | 0.024 | ||
| cdh5 | cadherin 5 | 0.024 | ||
| adam17a | a disintegrin and metalloproteinase domain 17a | 0.024 | ||
| ddc | dopa decarboxylase | 0.023 | ||
| im:7163548 | im:7163548 | 0.023 | ||
| mpz | myelin protein zero | 0.023 | ||
| nr4a2b | nuclear receptor subfamily 4, group A, member 2b | 0.023 | ||
| pgr | progesterone receptor | 0.021 | ||
| ncam1b | neural cell adhesion molecule 1b | 0.020 | ||
| trpv6 | transient receptor potential cation channel, subfamily V, member 6 | 0.020 | ||
| inha | inhibin, alpha | 0.020 | ||
| ccng1 | cyclin G1 | 0.019 | ||
| cyp17a1 | cytochrome P450, family 17, subfamily A, polypeptide 1 | 0.019 | Rat | |
| cadm2b | cell adhesion molecule 2b | 0.019 | ||
| hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.019 | ||
| htr1aa | 5-hydroxytryptamine (serotonin) receptor 1A a | 0.019 | ||
| vtg4 | vitellogenin 4 | 0.018 | ||
| ptgesl | prostaglandin E synthase 2-like | 0.018 | ||
| zgc:64114 | zgc:64114 | 0.018 | ||
| c1qc | complement component 1, q subcomponent, C chain | 0.018 | ||
| unc45b | unc-45 homolog B (C. elegans) | 0.018 | ||
| tlr21 | toll-like receptor 21 | 0.017 | ||
| foxp2 | forkhead box P2 | 0.017 | ||
| cdkrap3 | CDK5 regulatory subunit associated protein 3 | 0.017 | ||
| ucn3l | urocortin 3, like | 0.017 | ||
| xirp1 | xin actin-binding repeat containing 1 | 0.017 | ||
| cbr1l | carbonyl reductase 1-like | 0.017 | ||
| pafah1b1b | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b | 0.017 | ||
| dnajc3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.017 | ||
| crh | corticotropin releasing hormone | 0.017 | ||
| hsd17b1 | hydroxysteroid (17-beta) dehydrogenase 1 | 0.016 | ||
| nanos3 | nanos homolog 3 | 0.016 | ||
| mvp | major vault protein | 0.016 | ||
| paqr8 | progestin and adipoQ receptor family member VIII | 0.016 | ||
| ryr1b | ryanodine receptor 1b (skeletal) | 0.015 | ||
| npy8br | neuropeptide Y receptor Y8b | 0.015 | ||
| cldna | claudin a | 0.015 | ||
| chat | choline acetyltransferase | 0.015 | ||
| oprd1b | opioid receptor, delta 1b | 0.015 | Human | |
| limk2 | LIM domain kinase 2 | 0.015 | ||
| slc25a25a | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a | 0.015 | ||
| lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.015 | ||
| arf1 | ADP-ribosylation factor 1 | 0.014 | ||
| cdipt | CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) | 0.014 | ||
| ihha | Indian hedgehog homolog a | 0.014 | ||
| si:ch211-114c12.2 | si:ch211-114c12.2 | 0.014 | ||
| uts1 | urotensin 1 | 0.014 | ||
| gria1a | glutamate receptor, ionotropic, AMPA 1a | 0.014 | ||
| tpm4 | tropomyosin 4 | 0.014 | ||
| nppa | natriuretic peptide precursor A | 0.014 | ||
| galcb | galactosylceramidase b | 0.013 | ||
| gria3a | glutamate receptor, ionotropic, AMPA 3a | 0.013 | ||
| elmo1 | engulfment and cell motility 1 (ced-12 homolog, C. elegans) | 0.013 | ||
| ywhaqa | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a | 0.013 | ||
| cacnb1 | calcium channel, voltage-dependent, beta 1 subunit | 0.013 | ||
| or111-10 | odorant receptor, family D, subfamily 111, member 10 | 0.013 | ||
| ripk2 | receptor-interacting serine-threonine kinase 2 | 0.013 | ||
| dusp1 | dual specificity phosphatase 1 | 0.013 | ||
| si:ch211-209p5.2 | si:ch211-209p5.2 | 0.013 | ||
| dlg4 | discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila) | 0.013 | ||
| tph2 | tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) | 0.013 | ||
| extl3 | exostoses (multiple)-like 3 | 0.013 | ||
| bmpr1aa | bone morphogenetic protein receptor, type 1aa | 0.013 | ||
| gria2b | glutamate receptor, ionotropic, AMPA 2b | 0.013 | ||
| ndel1a | nudE nuclear distribution gene E homolog like 1 (A. nidulans) A | 0.013 | ||
| elovl5 | ELOVL family member 5, elongation of long chain fatty acids (yeast) | 0.012 | ||
| gnsa | glucosamine (N-acetyl)-6-sulfatase a | 0.012 | ||
| myh6 | myosin, heavy polypeptide 6, cardiac muscle, alpha | 0.012 | ||
| rnaseka | ribonuclease, RNase K a | 0.012 | ||
| nr4a1 | nuclear receptor subfamily 4, group A, member 1 | 0.012 | ||
| cldnd | claudin d | 0.012 | ||
| acvr2a | activin receptor IIa | 0.012 | ||
| npc1 | Niemann-Pick disease, type C1 | 0.012 | ||
| calr | calreticulin and calreticulin | 0.012 | ||
| LOC565839 | tumor necrosis factor alpha-induced protein 2-like | 0.012 | ||
| slc2a9l1 | solute carrier family 2 (facilitated glucose transporter), member 9-like 1 | 0.012 | ||
| nr5a2 | nuclear receptor subfamily 5, group A, member 2 | 0.012 | ||
| LOC555504 | novel protocadherin protein | 0.012 | ||
| gria4a | glutamate receptor, ionotropic, AMPA 4a | 0.012 | ||
| csrp3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.012 | ||
| rorcb | RAR-related orphan receptor C b | 0.012 | ||
| cldn2 | claudin 2 | 0.012 | ||
| alp | alkaline phosphatase | 0.011 | ||
| yod1 | YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae) | 0.011 | ||
| dmrta2 | doublesex and mab-3 related transcription factor like family A2 | 0.011 | ||
| mmp9 | matrix metalloproteinase 9 | 0.011 | ||
| inhbab | inhibin, beta Ab | 0.011 | ||
| helt | hey-like transcription factor | 0.011 | ||
| LOC100330405 | transmembrane protein 176B-like | 0.011 | ||
| pi4kb | phosphatidylinositol 4-kinase, catalytic, beta | 0.011 | ||
| tgfb3 | transforming growth factor, beta 3 | 0.011 | ||
| c1qtnf4 | C1q and tumor necrosis factor related protein 4 | 0.011 | ||
| slc12a3 | solute carrier family 12 (sodium/chloride transporters), member 3 | 0.011 | ||
| csrnp1a | cysteine-serine-rich nuclear protein 1a | 0.011 | ||
| rspo1 | R-spondin homolog (Xenopus laevis) | 0.011 | ||
| ahr2 | aryl hydrocarbon receptor 2 | 0.011 | ||
| hspb7 | heat shock protein family, alpha-crystallin-related, b7 | 0.011 | ||
| tm9sf2 | transmembrane 9 superfamily member 2 | 0.011 | ||
| nkx2.5 | NK2 transcription factor related 5 | 0.011 | ||
| mchr1b | melanin-concentrating hormone receptor 1b | 0.010 | ||
| scn1a | sodium channel, voltage-gated, type I, alpha | 0.010 | ||
| anxa5b | annexin A5b | 0.010 | ||
| chrm2a | cholinergic receptor, muscarinic 2a | 0.010 | ||
| dag1 | dystroglycan 1 | 0.010 | ||
| cyp3c1 | cytochrome P450, family 3, subfamily c, polypeptide 1 | 0.010 | ||
| reln | reelin | 0.010 | ||
| LOC100536254 | hypothetical protein LOC100536254 | 0.010 | ||
| xbp1 | X-box binding protein 1 | 0.010 | ||
| rad21 | RAD21 homolog (S. pombe) | 0.010 | ||
| chrna6 | cholinergic receptor, nicotinic, alpha 6 | 0.010 |