IMP
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regulation of transcription from rna polymerase ii promoter in response to oxidative stress
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
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Click on a gene's description to view its network relationships with genes known to be involved in "regulation of transcription from rna polymerase ii promoter in response to oxidative stress"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| hif1ab | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b | 0.693 | Human Mouse Rat | |
| copeb | core promoter element binding protein | 0.450 | ||
| epas1b | endothelial PAS domain protein 1b | 0.444 | Mouse | |
| cyp1a | cytochrome P450, family 1, subfamily A | 0.235 | ||
| fabp11a | fatty acid binding protein 11a | 0.179 | ||
| trpv6 | transient receptor potential cation channel, subfamily V, member 6 | 0.155 | ||
| mt2 | metallothionein 2 | 0.153 | ||
| igfbp1a | insulin-like growth factor binding protein 1a | 0.146 | ||
| zgc:113210 | zgc:113210 | 0.127 | ||
| tm9sf2 | transmembrane 9 superfamily member 2 | 0.116 | ||
| aqp8a.1 | aquaporin 8a, tandem duplicate 1 | 0.099 | ||
| socs3a | suppressor of cytokine signaling 3a | 0.084 | ||
| bactin1 | bactin1 | 0.074 | ||
| socs3b | suppressor of cytokine signaling 3b | 0.074 | ||
| si:ch211-114c12.2 | si:ch211-114c12.2 | 0.064 | ||
| nfe2l2 | nuclear factor (erythroid-derived 2)-like 2 | 0.063 | ||
| park7 | parkinson disease (autosomal recessive, early onset) 7 | 0.061 | ||
| ldhba | lactate dehydrogenase Ba | 0.061 | ||
| gapdh | glyceraldehyde-3-phosphate dehydrogenase | 0.060 | ||
| sod2 | superoxide dismutase 2, mitochondrial | 0.057 | ||
| rp2 | retinitis pigmentosa 2 (X-linked recessive) | 0.055 | ||
| ef1a | elongation factor 1-alpha | 0.055 | ||
| aplp2 | amyloid beta (A4) precursor-like protein 2 | 0.053 | ||
| hsd17b12b | hydroxysteroid (17-beta) dehydrogenase 12b | 0.053 | ||
| acadm | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 0.047 | ||
| sf1 | splicing factor 1 | 0.046 | ||
| slc30a7 | solute carrier family 30 (zinc transporter), member 7 | 0.046 | ||
| cnn2 | calponin 2 | 0.043 | ||
| birc2 | baculoviral IAP repeat-containing 2 | 0.043 | ||
| cyp3c1 | cytochrome P450, family 3, subfamily c, polypeptide 1 | 0.043 | ||
| jun | jun proto-oncogene | 0.041 | ||
| si:ch211-260p9.1 | si:ch211-260p9.1 | 0.041 | ||
| gnb1a | guanine nucleotide binding protein (G protein), beta polypeptide 1a | 0.040 | ||
| mmp9 | matrix metalloproteinase 9 | 0.040 | ||
| tspo | translocator protein | 0.040 | ||
| ca2 | carbonic anhydrase II | 0.039 | ||
| klf2a | Kruppel-like factor 2a | 0.039 | ||
| gpia | glucose phosphate isomerase a | 0.038 | ||
| zgc:101724 | zgc:101724 | 0.038 | ||
| calcrla | calcitonin receptor-like a | 0.038 | ||
| maff | v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian) | 0.037 | ||
| mcl1a | myeloid cell leukemia sequence 1a | 0.036 | ||
| eno3 | enolase 3, (beta, muscle) | 0.035 | ||
| adipor2 | adiponectin receptor 2 | 0.035 | ||
| sec24c | SEC24 family, member C (S. cerevisiae) | 0.034 | ||
| atf3 | activating transcription factor 3 | 0.033 | ||
| socs1 | suppressor of cytokine signaling 1 | 0.033 | ||
| kcnh1 | potassium voltage-gated channel, subfamily H (eag-related), member 1 | 0.033 | ||
| pdcd10a | programmed cell death 10a | 0.032 | ||
| sbf1 | SET binding factor 1 | 0.032 | ||
| limk2 | LIM domain kinase 2 | 0.032 | ||
| abcc5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.030 | ||
| LOC570775 | protein argonaute-1-like | 0.030 | ||
| esama | endothelial cell adhesion molecule a | 0.030 | ||
| cnppd1 | cyclin Pas1/PHO80 domain containing 1 | 0.030 | ||
| eif2c4 | eukaryotic translation initiation factor 2C, 4 | 0.029 | ||
| hsd17b12a | hydroxysteroid (17-beta) dehydrogenase 12a | 0.029 | ||
| ahr2 | aryl hydrocarbon receptor 2 | 0.028 | ||
| si:dkey-12o15.1 | si:dkey-12o15.1 | 0.027 | ||
| prkci | protein kinase C, iota | 0.027 | ||
| pnrc2 | proline-rich nuclear receptor coactivator 2 | 0.027 | ||
| sdha | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.027 | ||
| atf4b2 | activating transcription factor 4b2 | 0.027 | Human | |
| si:dkeyp-104h9.6 | si:dkeyp-104h9.6 | 0.027 | ||
| actn1 | actinin, alpha 1 | 0.026 | ||
| zgc:153148 | zgc:153148 | 0.026 | ||
| junb | jun B proto-oncogene | 0.025 | ||
| spg11 | spastic paraplegia 11 | 0.025 | ||
| dusp5 | dual specificity phosphatase 5 | 0.025 | ||
| kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.025 | ||
| nfkbiab | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b | 0.024 | ||
| srsf6b | serine/arginine-rich splicing factor 6b | 0.024 | ||
| gcm2 | glial cells missing homolog 2 (Drosophila) | 0.024 | ||
| ptgs2a | prostaglandin-endoperoxide synthase 2a | 0.023 | ||
| jak1 | Janus kinase 1 | 0.022 | ||
| ptprb | protein tyrosine phosphatase, receptor type, b | 0.022 | ||
| eif1b | eukaryotic translation initiation factor 1B | 0.021 | ||
| slc7a3 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 | 0.021 | ||
| ptgs1 | prostaglandin-endoperoxide synthase 1 | 0.021 | ||
| vdrb | vitamin D receptor b | 0.021 | ||
| phf20b | PHD finger protein 20, b | 0.020 | ||
| actn4 | actinin, alpha 4 | 0.020 | ||
| lgals9l1 | lectin, galactoside-binding, soluble, 9 (galectin 9)-like 1 | 0.020 | ||
| zgc:110775 | zgc:110775 | 0.020 | ||
| mtx2 | metaxin 2 | 0.019 | ||
| mcl1b | myeloid cell leukemia sequence 1b | 0.019 | ||
| srsf5b | serine/arginine-rich splicing factor 5b | 0.019 | ||
| si:dkey-177p2.6 | si:dkey-177p2.6 | 0.019 | ||
| zgc:112056 | zgc:112056 | 0.019 | ||
| cdk10 | cyclin-dependent kinase 10 | 0.018 | ||
| flt1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.018 | ||
| dab2 | disabled homolog 2 (Drosophila) | 0.018 | ||
| foxo3a | forkhead box O3A | 0.018 | ||
| slc20a1b | solute carrier family 20, member 1b | 0.017 | ||
| casrl | calcium-sensing receptor, like | 0.017 | ||
| wu:fj39b01 | wu:fj39b01 | 0.016 | ||
| zgc:158327 | zgc:158327 | 0.016 | ||
| mstna | myostatin a | 0.016 | ||
| plekhg5a | pleckstrin homology domain containing, family G (with RhoGef domain) member 5a | 0.016 | ||
| igf2b | insulin-like growth factor 2b | 0.016 | ||
| si:dkey-21k24.2 | si:dkey-21k24.2 | 0.016 | ||
| sat1a | spermidine/spermine N1-acetyltransferase 1a | 0.016 | ||
| tgfbr2 | transforming growth factor, beta receptor II | 0.016 | ||
| acaca | acetyl-Coenzyme A carboxylase alpha | 0.016 | ||
| cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.015 | ||
| fosl2 | fos-like antigen 2 | 0.015 | ||
| tob1b | transducer of ERBB2, 1b | 0.015 | ||
| csrnp1a | cysteine-serine-rich nuclear protein 1a | 0.015 | ||
| gpr182 | G protein-coupled receptor 182 | 0.015 | ||
| si:ch73-60e21.1 | si:ch73-60e21.1 | 0.015 | ||
| sqstm1 | sequestosome 1 | 0.015 | ||
| cnot1 | CCR4-NOT transcription complex, subunit 1 | 0.014 | ||
| arl6ip1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.014 | ||
| eif2c3 | eukaryotic translation initiation factor 2C, 3 | 0.014 | ||
| zgc:152984 | zgc:152984 | 0.014 | ||
| bhlhe40 | basic helix-loop-helix family, member e40 | 0.014 | ||
| aqp1a.1 | aquaporin 1a, tandem duplicate 1 | 0.014 | ||
| cat | catalase | 0.014 | ||
| ddx3 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 | 0.014 | ||
| slc8a1b | solute carrier family 8 (sodium/calcium exchanger), member 1b | 0.014 | ||
| nfe2l1 | nuclear factor, erythroid derived 2,-like 1 | 0.014 | ||
| nsdhl | NAD(P) dependent steroid dehydrogenase-like | 0.014 | ||
| ren | renin | 0.014 | ||
| vsg1 | vessel-specific 1 | 0.014 | ||
| eaf2 | ELL associated factor 2 | 0.014 | ||
| si:ch211-212m21.5 | si:ch211-212m21.5 | 0.014 | ||
| zgc:100919 | zgc:100919 | 0.014 | ||
| atp2b2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.014 | ||
| zgc:153997 | zgc:153997 | 0.014 | ||
| cx45.6 | connexin 45.6 | 0.013 | ||
| cltca | clathrin, heavy polypeptide a (Hc) | 0.013 | ||
| rtn4a | reticulon 4a | 0.013 | ||
| zgc:77235 | zgc:77235 | 0.013 | ||
| prmt1 | protein arginine methyltransferase 1 | 0.013 | ||
| sik2b | salt-inducible kinase 2b | 0.013 | ||
| mif | macrophage migration inhibitory factor | 0.013 | ||
| lgals3l | lectin, galactoside-binding, soluble, 3 (galectin 3)-like | 0.013 | ||
| gna12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.013 | ||
| slc25a25a | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a | 0.013 | ||
| nme2b.1 | non-metastatic cells 2b.1, protein (NM23B) expressed in | 0.013 | ||
| bactin2 | bactin2 | 0.013 | ||
| trdmt1 | tRNA aspartic acid methyltransferase 1 | 0.012 | ||
| gstp1 | glutathione S-transferase pi | 0.012 | ||
| kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.012 | ||
| zgc:110380 | zgc:110380 | 0.012 | ||
| cald1 | caldesmon 1 | 0.012 | ||
| cldn12 | claudin 12 | 0.012 | ||
| rqcd1 | RCD1 required for cell differentiation1 homolog (S. pombe) | 0.011 | ||
| ndufs8a | NADH dehydrogenase (ubiquinone) Fe-S protein 8a | 0.011 | ||
| mmp15a | matrix metallopeptidase 15a | 0.011 | ||
| selenbp1 | selenium binding protein 1 | 0.011 | ||
| zgc:77262 | zgc:77262 | 0.011 | ||
| ckmt2 | creatine kinase, mitochondrial 2 (sarcomeric) | 0.011 | ||
| atp5a1 | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 0.011 | ||
| stat1a | signal transduction and activation of transcription 1a | 0.011 | ||
| si:dkey-177e13.4 | si:dkey-177e13.4 | 0.011 | ||
| lgals2b | lectin, galactoside-binding, soluble, 2b | 0.011 | ||
| wsb1 | WD repeat and SOCS box-containing 1 | 0.011 | ||
| fkbp5 | FK506 binding protein 5 | 0.011 | ||
| zgc:77101 | zgc:77101 | 0.011 | ||
| ppp1cb | protein phosphatase 1, catalytic subunit, beta isoform | 0.011 | ||
| slc39a1 | solute carrier family 39 (zinc transporter), member 1 | 0.011 | ||
| stc1l | stanniocalcin 1, like | 0.011 | ||
| si:rp71-39b20.7 | si:rp71-39b20.7 | 0.011 | ||
| sat1b | spermidine/spermine N1-acetyl transferase 1b | 0.010 | ||
| rhag | Rhesus blood group-associated glycoprotein | 0.010 | ||
| gclc | glutamate-cysteine ligase, catalytic subunit | 0.010 | ||
| zgc:112986 | zgc:112986 | 0.010 | ||
| arhgap29a | Rho GTPase activating protein 29a | 0.010 | ||
| tlr3 | toll-like receptor 3 | 0.010 | ||
| gdf11 | growth differentiation factor 11 | 0.010 | ||
| nf1b | neurofibromin 1b | 0.010 | ||
| igf2a | insulin-like growth factor 2a | 0.010 | ||
| acadl | acyl-Coenzyme A dehydrogenase, long chain | 0.010 | ||
| arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 0.010 | ||
| slmo2 | slowmo homolog 2 (Drosophila) | 0.010 | ||
| rhoab | ras homolog gene family, member Ab | 0.010 |