IMP
Process View
protein destabilization
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "protein destabilization"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| bmp4 | bone morphogenetic protein 4 | 0.780 | ||
| bmp2b | bone morphogenetic protein 2b | 0.539 | Mouse | |
| tp53 | tumor protein p53 | 0.113 | ||
| aurkb | aurora kinase B | 0.077 | ||
| apoeb | apolipoprotein Eb | 0.057 | ||
| msxb | muscle segment homeobox B | 0.046 | ||
| fgf24 | fibroblast growth factor 24 | 0.041 | ||
| ets1a | v-ets erythroblastosis virus E26 oncogene homolog 1a | 0.035 | ||
| lama5 | laminin, alpha 5 | 0.030 | ||
| bmp2a | bone morphogenetic protein 2a | 0.029 | Mouse | |
| ccng1 | cyclin G1 | 0.027 | ||
| sdc2 | syndecan 2 | 0.026 | ||
| nap1l1 | nucleosome assembly protein 1, like 1 | 0.026 | ||
| bambia | BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a | 0.025 | ||
| hspa5 | heat shock protein 5 | 0.024 | ||
| zgc:64114 | zgc:64114 | 0.023 | ||
| fgf8a | fibroblast growth factor 8 a | 0.023 | ||
| actn4 | actinin, alpha 4 | 0.022 | ||
| ptger4a | prostaglandin E receptor 4 (subtype EP4) a | 0.021 | ||
| ef1a | elongation factor 1-alpha | 0.021 | ||
| dlx3b | distal-less homeobox gene 3b | 0.021 | ||
| igf1rb | insulin-like growth factor 1b receptor | 0.020 | ||
| pcna | proliferating cell nuclear antigen | 0.020 | ||
| ddx18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.019 | ||
| ssb | Sjogren syndrome antigen B (autoantigen La) | 0.019 | ||
| smad7 | MAD, mothers against decapentaplegic homolog 7 (Drosophila) | 0.019 | ||
| si:ch211-204c21.1 | si:ch211-204c21.1 | 0.018 | ||
| rbp4 | retinol binding protein 4, plasma | 0.017 | ||
| bbc3 | BCL2 binding component 3 | 0.015 | ||
| pes | pescadillo | 0.014 | ||
| cx43 | connexin 43 | 0.014 | ||
| zgc:110388 | zgc:110388 | 0.014 | ||
| runx1 | runt-related transcription factor 1 | 0.014 | ||
| npm4 | nucleophosmin/nucleoplasmin, 4 | 0.014 | Mouse | |
| xbp1 | X-box binding protein 1 | 0.013 | ||
| ttk | ttk protein kinase | 0.013 | ||
| plod3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 0.013 | ||
| mmp9 | matrix metalloproteinase 9 | 0.013 | ||
| dact2 | dapper homolog 2, antagonist of beta-catenin (xenopus) | 0.013 | ||
| wdr43 | WD repeat domain 43 | 0.013 | ||
| acvr1b | activin A receptor, type IB | 0.013 | ||
| bcl2l1 | bcl2-like 1 | 0.012 | ||
| hsp47 | heat shock protein 47 | 0.012 | ||
| ccna2 | cyclin A2 | 0.012 | ||
| ercc2 | excision repair cross-complementing rodent repair deficiency, complementation group 2 | 0.012 | ||
| waca | WW domain containing adaptor with coiled-coil a | 0.012 | ||
| ccnb1 | cyclin B1 | 0.011 | ||
| dvl3 | dishevelled, dsh homolog 3 (Drosophila) | 0.011 | ||
| gdf6a | growth differentiation factor 6a | 0.011 | ||
| zcchc7 | zinc finger, CCHC domain containing 7 | 0.011 | ||
| mad2l1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.011 | ||
| zgc:152925 | zgc:152925 | 0.011 | ||
| znf143 | zinc finger protein 143 | 0.011 | ||
| cxcr4a | chemokine (C-X-C motif) receptor 4a | 0.010 | ||
| lpp | LIM domain containing preferred translocation partner in lipoma | 0.010 | ||
| etv5b | ets variant 5b | 0.010 | ||
| cpa5 | carboxypeptidase A5 | 0.010 | ||
| spry4 | sprouty (Drosophila) homolog 4 | 0.010 | ||
| mcm5 | MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) | 0.010 | ||
| crip2 | cysteine-rich protein 2 | 0.010 |