IMP: Integrative Multi-species Prediction

Danio rerio

14 genes annotated in zebrafish

Multi-species View

positive regulation of locomotion

GO:0040017

Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of locomotion"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of locomotion" (in gray)

Name	Description	Probability	Func Analog Organism
kdrl	kinase insert domain receptor like	0.471	Zebrafish
col14a1	collagen, type XIV, alpha 1	0.441
pitx3	paired-like homeodomain transcription factor 3	0.347
fras1	Fraser syndrome 1	0.326
tll1	tolloid-like 1	0.292
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.280
tie1	endothelium-specific receptor tyrosine kinase 1	0.185
bmp4	bone morphogenetic protein 4	0.178	Human
flt4	fms-related tyrosine kinase 4	0.172	Human Zebrafish
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.171
apoeb	apolipoprotein Eb	0.165
lamc1	laminin, gamma 1	0.142	Worm
tal1	T-cell acute lymphocytic leukemia 1	0.134
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.119
ptgs1	prostaglandin-endoperoxide synthase 1	0.113
alcamb	activated leukocyte cell adhesion molecule b	0.107
ptprf	protein tyrosine phosphatase, receptor type, F	0.101
LOC569128	hypothetical protein LOC569128	0.093
myf5	myogenic factor 5	0.091
itgb1b	integrin, beta 1b	0.090	Worm
efnb2a	ephrin B2a	0.086
lcp1	lymphocyte cytosolic plastin 1	0.085
cdh2	cadherin 2, neuronal	0.083
ptmaa	prothymosin, alpha a	0.079
mpx	myeloid-specific peroxidase	0.076
efnb3b	ephrin B3b	0.073
cmyb	transcription factor cmyb	0.071
kdr	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.070	Human Zebrafish
tbx1	T-box 1	0.066
lpar1	lysophosphatidic acid receptor 1	0.062	Rat
slit3	slit (Drosophila) homolog 3	0.061	Fly
erg	v-ets erythroblastosis virus E26 oncogene like (avian)	0.061
spns2	spinster homolog 2 (Drosophila)	0.058
lamb1a	laminin, beta 1a	0.052
rx3	retinal homeobox gene 3	0.051	Zebrafish
aplnra	apelin receptor a	0.051
itgb1b.2	integrin, beta 1b.2	0.050	Rat Worm
itgb1a	integrin, beta 1a	0.049	Worm
prox1	prospero-related homeobox gene 1	0.049
shha	sonic hedgehog a	0.048
jag1a	jagged 1a	0.048
gap43	growth associated protein 43	0.047
gdf6a	growth differentiation factor 6a	0.046
bnc2	basonuclin 2	0.046
igf1	insulin-like growth factor 1	0.045
sulf1	sulfatase 1	0.044
spi1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.044
col12a1	collagen, type XII, alpha 1	0.043
nkx2.1a	NK2 homeobox 1a	0.043
postn	periostin, osteoblast specific factor	0.042
itga5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.042	Worm
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.040
igf1rb	insulin-like growth factor 1b receptor	0.040	Human
ptger2a	prostaglandin E receptor 2a (subtype EP2)	0.039
crabp2a	cellular retinoic acid binding protein 2, a	0.039
nrp2b	neuropilin 2b	0.039
gata6	GATA-binding protein 6	0.037
esr2b	estrogen receptor 2b	0.036
tp63	tumor protein p63	0.036
bmp2a	bone morphogenetic protein 2a	0.036	Mouse
si:dkeyp-50f5.1	si:dkeyp-50f5.1	0.035
esrra	estrogen-related receptor alpha	0.035
runx1	runt-related transcription factor 1	0.035
atoh7	atonal homolog 7	0.035
atp6v1al	ATPase, H+ transporting, lysosomal V1 subunit A, like	0.035
egr1	early growth response 1	0.035
ptprk	protein tyrosine phosphatase, receptor type, K	0.035
tbx20	T-box 20	0.035
szl	sizzled	0.034
ptrfb	polymerase I and transcript release factor b	0.034
ephb4a	eph receptor B4a	0.033
kita	kit receptor a	0.033	Zebrafish
foxn4	forkhead box N4	0.033
cntn2	contactin 2	0.032
vent	ventral expressed homeobox	0.032
col1a2	collagen, type I, alpha 2	0.032
grhl2b	grainyhead-like 2b (Drosophila)	0.031
fn1	fibronectin 1	0.031	Rat
has2	hyaluronan synthase 2	0.031	Human
srf	serum response factor	0.031
atp1b1b	ATPase, Na+/K+ transporting, beta 1b polypeptide	0.031
ptges	prostaglandin E synthase	0.031
gpr126	G protein-coupled receptor 126	0.030
gata4	GATA-binding protein 4	0.030	Zebrafish
tnc	tenascin C	0.030
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.029
wnt10a	wingless-type MMTV integration site family, member 10a	0.029
lmna	lamin A	0.029
tie2	endothelium-specific receptor tyrosine kinase 2	0.029	Human
eno2	enolase 2	0.029
lpp	LIM domain containing preferred translocation partner in lipoma	0.029
itga3b	integrin, alpha 3b	0.028
lama4	laminin, alpha 4	0.028	Worm
cyp1a	cytochrome P450, family 1, subfamily A	0.028
cyt1	type I cytokeratin, enveloping layer	0.028
frem3	Fras1 related extracellular matrix 3	0.028
rhogb	ras homolog gene family, member Gb	0.028	Zebrafish
igfbp5a	insulin-like growth factor binding protein 5a	0.028
f2r	coagulation factor II (thrombin) receptor	0.027	Human Mouse
cdh5	cadherin 5	0.027
sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.027
ca2	carbonic anhydrase II	0.027
cdh1	cadherin 1, epithelial	0.026
vcana	versican a	0.026
tgfb2	transforming growth factor, beta 2	0.026	Human Rat
eng1a	engrailed 1a	0.025
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.025
jun	jun proto-oncogene	0.025
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.025
sox32	SRY-box containing gene 32	0.025
epas1b	endothelial PAS domain protein 1b	0.024
fabp11a	fatty acid binding protein 11a	0.024
gsna	gelsolin a	0.024
large	like-glycosyltransferase	0.024
pbx1a	pre-B-cell leukemia transcription factor 1a	0.024
col1a1a	collagen, type I, alpha 1a	0.024	Human
prdm14	PR domain containing 14	0.024
col5a3b	collagen type V alpha-3b	0.023
hand2	heart and neural crest derivatives expressed transcript 2	0.023
mcamb	melanoma cell adhesion molecule b	0.023	Rat
nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.023
mmp9	matrix metalloproteinase 9	0.023	Human
lama2	laminin, alpha 2	0.023
hspg2	heparan sulfate proteoglycan 2	0.023
aplnrb	apelin receptor b	0.022
hmcn2	hemicentin 2	0.022
yrk	Yes-related kinase	0.022
ptprc	protein tyrosine phosphatase, receptor type, C	0.022	Human
klf4a	Kruppel-like transcription factor 4a	0.022
mkxa	mohawk homeobox a	0.022
sema3fb	semaphorin 3fb	0.022
ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.022
osr1	odd-skipped related 1 (Drosophila)	0.022
prrx1a	paired related homeobox 1a	0.022
hpd	4-hydroxyphenylpyruvate dioxygenase	0.022
sox5	SRY-box containing gene 5	0.022
cbfb	core-binding factor, beta subunit	0.022
cx30.3	connexin 30.3	0.022
nkx2.3	NK2 transcription factor related 3	0.021
nog2	noggin 2	0.021
col5a2l	collagen, type V, alpha 2-like	0.021
lmo2	LIM domain only 2 (rhombotin-like 1)	0.021
cxcl12a	chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)	0.021
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.021	Human
sox17	SRY-box containing gene 17	0.021
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.021
tgfb1a	transforming growth factor, beta 1a	0.021	Human
neurod	neurogenic differentiation	0.021
xirp2a	xin actin-binding repeat containing 2a	0.021
grna	granulin a	0.021
bmp7a	bone morphogenetic protein 7a	0.021
pxn	paxillin	0.020
nrp1a	neuropilin 1a	0.020	Mouse
sp8a	sp8 transcription factor a	0.020
rhag	Rhesus blood group-associated glycoprotein	0.020
podxl	podocalyxin-like	0.020	Human
itgb1b.1	integrin, beta 1b.1	0.020	Worm
vegfc	vascular endothelial growth factor c	0.020
ucn3l	urocortin 3, like	0.020
adora2aa	adenosine A2a receptor a	0.020
esr1	estrogen receptor 1	0.019
copeb	core promoter element binding protein	0.019
wnt5b	wingless-type MMTV integration site family, member 5b	0.019	Human
hhip	hedgehog interacting protein	0.019
zgc:195154	zgc:195154	0.019
ptena	phosphatase and tensin homolog A	0.019
foxi1	forkhead box I1	0.019
plekhg4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4	0.019
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.019
plxnb2a	plexin b2a	0.019
fes	feline sarcoma oncogene	0.018
nkd1	naked cuticle homolog 1 (Drosophila)	0.018
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.018	Worm
slit1a	slit homolog 1a (Drosophila)	0.018	Fly
ccl25b	chemokine (C-C motif) ligand 25b	0.018
arf2	ADP-ribosylation factor 2	0.018
dlc	deltaC	0.018
bhlhe41	basic helix-loop-helix family, member e41	0.018
slit1b	slit homolog 1b (Drosophila)	0.018	Fly
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.017
mtp	microsomal triglyceride transfer protein	0.017
ldb2a	LIM-domain binding factor 2a	0.017
fgfr1a	fibroblast growth factor receptor 1a	0.017
twist3	twist3	0.017
prnprs3	prion protein, related sequence 3	0.017
mmp2	matrix metalloproteinase 2	0.017
si:dkeyp-22b2.3	si:dkeyp-22b2.3	0.017
celsr1a	cadherin EGF LAG seven-pass G-type receptor 1a	0.017
rarga	retinoic acid receptor gamma a	0.017
gpc4	glypican 4	0.017
bon	bonnie and clyde	0.017
irx3a	iroquois homeobox protein 3a	0.017
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.017	Rat
timp2b	tissue inhibitor of metalloproteinase 2b	0.017
utrn	utrophin	0.017
bbs4	Bardet-Biedl syndrome 4	0.017
smad3a	MAD homolog 3a (Drosophila)	0.016
nlgn2a	neuroligin 2a	0.016
rspo1	R-spondin homolog (Xenopus laevis)	0.016
alcama	activated leukocyte cell adhesion molecule a	0.016
coro1a	coronin, actin binding protein, 1A	0.016	Mouse
cacnb2b	calcium channel, voltage-dependent, beta 2b	0.016	Worm
celsr1b	cadherin EGF LAG seven-pass G-type receptor 1b	0.016
fkbp10	FK506 binding protein 10	0.016
smyd1b	SET and MYND domain containing 1b	0.016
bmpr2a	bone morphogenetic protein receptor, type II a (serine/threonine kinase)	0.016
cyp2y3	cytochrome P450, family 2, subfamily Y, polypeptide 3	0.016
pou1f1	POU domain, class 1, transcription factor 1	0.016
krml2.2	Kreisler (mouse) maf-related leucine zipper homolog 2.2	0.016
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.016
lyz	lysozyme	0.016
cx43	connexin 43	0.016
tbx16	T-box gene 16	0.015
six4.3	sine oculis homeobox homolog 4.3	0.015
ptger4a	prostaglandin E receptor 4 (subtype EP4) a	0.015
mrc1a	mannose receptor, C type 1a	0.015
mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.015
myod1	myogenic differentiation 1	0.015
ptk2.1	protein tyrosine kinase 2a	0.015	Human Rat
lats1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.015
tbx2a	T-box gene 2a	0.015
arpc1b	actin related protein 2/3 complex, subunit 1B	0.015
sdc2	syndecan 2	0.014
socs3a	suppressor of cytokine signaling 3a	0.014
chsy1	chondroitin sulfate synthase 1	0.014
sim1a	single-minded homolog 1a (Drosophila)	0.014
fzd2	frizzled homolog 2	0.014
twist1a	twist1a	0.014
fli1a	friend leukemia integration 1a	0.014
satb2	SATB homeobox 2	0.014
tjp1	tight junction protein 1 (zona occludens 1)	0.014
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.014
zgc:171802	zgc:171802	0.014
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.014	Worm
otomp	otolith matrix protein	0.014
itgb3a	integrin beta 3a	0.014	Mouse Worm
nkx2.5	NK2 transcription factor related 5	0.014
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.014
plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.014
lhx2b	LIM homeobox 2b	0.014
si:dkey-12o15.1	si:dkey-12o15.1	0.014
rdh10a	retinol dehydrogenase 10a	0.014
zgc:63721	zgc:63721	0.013
nlgn3a	neuroligin 3a	0.013
rx2	retinal homeobox gene 2	0.013	Zebrafish
gmfg	glia maturation factor, gamma	0.013
klf4	Kruppel-like factor 4	0.013
mpll	myeloproliferative leukemia virus oncogene, like	0.013
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.013
emx3	empty spiracles homeobox 3	0.013
tpst1	tyrosylprotein sulfotransferase 1	0.013
hbbe1.1	hemoglobin beta embryonic-1.1	0.013
wnt4a	wingless-type MMTV integration site family, member 4a	0.013
dkk1b	dickkopf 1b	0.013
foxd3	forkhead box D3	0.013
lingo1a	leucine rich repeat and Ig domain containing 1a	0.013
nos2a	nitric oxide synthase 2a, inducible	0.013
six4b	sine oculis homeobox homolog 4b	0.013
hgd	homogentisate 1,2-dioxygenase	0.013
vsx2	visual system homeobox 2	0.013
dlx4b	distal-less homeobox gene 4b	0.013
gja3	gap junction protein, alpha 3	0.012
rock2b	rho-associated, coiled-coil containing protein kinase 2b	0.012
sb:cb176	sb:cb176	0.012
hes6	hairy and enhancer of split 6 (Drosophila)	0.012
runx3	runt-related transcription factor 3	0.012
mbnl1	muscleblind-like (Drosophila)	0.012
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.012
hsp47	heat shock protein 47	0.012
cnn2	calponin 2	0.012
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.012
cdc42	cell division cycle 42	0.012	Zebrafish
LOC566708	FL cytokine receptor-like	0.012
klf2a	Kruppel-like factor 2a	0.012
mdka	midkine-related growth factor	0.012
gata5	GATA-binding protein 5	0.012	Zebrafish
zgc:165373	zgc:165373	0.012
per2	period homolog 2 (Drosophila)	0.012
sgk1	serum/glucocorticoid regulated kinase 1	0.012
irx4a	iroquois homeobox protein 4a	0.012
neu4	sialidase 4	0.012
bmper	BMP binding endothelial regulator	0.012
dytn	dystrotelin	0.012
esrrga	estrogen-related receptor gamma a	0.012
plce1	phospholipase C, epsilon 1	0.012
nrp2a	neuropilin 2a	0.012
hnf1a	HNF1 homeobox a	0.012
emp2	epithelial membrane protein 2	0.012
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.012
mapk3	mitogen-activated protein kinase 3	0.012
si:dkey-261h17.1	si:dkey-261h17.1	0.011
col19a1	collagen, type XIX, alpha 1	0.011
robo1	roundabout homolog 1	0.011
ldb1a	LIM-domain binding factor 1a	0.011
zbtb4	zinc finger and BTB domain containing 4	0.011
cyp24a1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.011
sox9a	SRY-box containing gene 9a	0.011	Human Mouse
pomca	proopiomelanocortin a	0.011
dnmt4	DNA (cytosine-5-)-methyltransferase 4	0.011
myhz1.1	myosin, heavy polypeptide 1.1, skeletal muscle	0.011
nipblb	novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)	0.011
plxnd1	plexin D1	0.011
myo10l1	myosin X-like 1	0.011
lrrc33	leucine rich repeat containing 33	0.011
camk2g1	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1	0.011
gli2a	GLI-Kruppel family member GLI2a	0.011
anxa2b	annexin A2b	0.011
pkd2	polycystic kidney disease 2	0.011
tram1	translocating chain-associating membrane protein 1	0.011
stc1l	stanniocalcin 1, like	0.011
dtnb	dystrobrevin, beta	0.011
im:7162646	im:7162646	0.011
zfpl1	zinc finger protein-like 1	0.011
plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	0.011
igf1ra	insulin-like growth factor 1a receptor	0.011	Human
wnt11	wingless-type MMTV integration site family, member 11	0.011
crb2a	crumbs homolog 2a	0.011
ptmab	prothymosin, alpha b	0.011
bmp7b	bone morphogenetic protein 7b	0.011
ncf1	neutrophil cytosolic factor 1	0.011
foxc1b	forkhead box C1b	0.011
six1b	sine oculis homeobox homolog 1b	0.011
cxcr3.2	chemokine (C-X-C motif) receptor 3.2	0.011	Zebrafish
mst1rb	macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b	0.011
dacha	dachshund a	0.011
vwf	von Willebrand factor	0.011
fabp10a	fatty acid binding protein 10a, liver basic	0.011
trpm6	transient receptor potential cation channel, subfamily M, member 6	0.010
arf1	ADP-ribosylation factor 1	0.010
pax8	paired box gene 8	0.010
dag1	dystroglycan 1	0.010
her1	hairy-related 1	0.010
spry4	sprouty (Drosophila) homolog 4	0.010
dpysl5b	dihydropyrimidinase-like 5b	0.010
meis2.2	myeloid ecotropic viral integration site 2.2	0.010
agr2	anterior gradient homolog 2 (Xenopus laevis)	0.010
pomt2	protein-O-mannosyltransferase 2	0.010
bcam	basal cell adhesion molecule (Lutheran blood group)	0.010
desmb	desmin b	0.010
fgf8a	fibroblast growth factor 8 a	0.010
gcm2	glial cells missing homolog 2 (Drosophila)	0.010
cap1	Cap1 CAP, adenylate cyclase-associated protein 1	0.010
slc8a4a	solute carrier family 8 (sodium/calcium exchanger), member 4a	0.010