IMP: Integrative Multi-species Prediction

Danio rerio

2 genes annotated in zebrafish

Multi-species View

regulation of anterior head development

GO:2000742

Any process that modulates the frequency, rate or extent of anterior head development.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of anterior head development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of anterior head development" (in gray)

Name	Description	Probability	Func Analog Organism
wnt1	wingless-type MMTV integration site family, member 1	0.999	Zebrafish
wnt10a	wingless-type MMTV integration site family, member 10a	0.979	Zebrafish
tbx1	T-box 1	0.931
wnt4a	wingless-type MMTV integration site family, member 4a	0.927	Zebrafish
wnt9b	wingless-type MMTV integration site family, member 9B	0.918	Zebrafish
wnt2	wingless-type MMTV integration site family member 2	0.816	Zebrafish
grem1a	gremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis)	0.803
wnt3a	wingless-type MMTV integration site family, member 3A	0.785	Zebrafish
wnt3	wingless-type MMTV integration site family, member 3	0.746	Zebrafish
wnt10b	wingless-type MMTV integration site family, member 10b	0.657	Zebrafish
gbx2	gastrulation brain homeo box 2	0.635
wnt9a	wingless-type MMTV integration site family, member 9A	0.581	Zebrafish
bmp2a	bone morphogenetic protein 2a	0.515
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.509
fbn2b	fibrillin 2b	0.426
dkk1b	dickkopf 1b	0.385
fgf17	fibroblast growth factor 17	0.363
zfyve26	zinc finger, FYVE domain containing 26	0.343
hnf1ba	HNF1 homeobox Ba	0.324
sfrp1b	secreted frizzled-related protein 1b	0.300
wnt16	wingless-type MMTV integration site family, member 16	0.286
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.268	Zebrafish
col11a2	collagen type XI alpha-2	0.267
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.260	Zebrafish
dharma	dharma	0.249
admp	anti-dorsalizing morphogenic protein	0.231
wnt5b	wingless-type MMTV integration site family, member 5b	0.209	Zebrafish
wnt8b	wingless-type MMTV integration site family, member 8b	0.206	Zebrafish
lef1	lymphocyte enhancer binding factor 1	0.203
hoxd4a	homeo box D4a	0.202
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.194	Zebrafish
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.184
gli1	GLI-Kruppel family member 1	0.178
foxn4	forkhead box N4	0.166
msxb	muscle segment homeobox B	0.164
wnt4b	wingless-type MMTV integration site family, member 4b	0.156	Zebrafish
twist3	twist3	0.155
hmx4	H6 family homeobox 4	0.146
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.143
eng2a	engrailed 2a	0.143
ntla	no tail a	0.140
foxj1a	forkhead box J1a	0.137
hmx1	H6 homeo box 1	0.136
map2k7	mitogen-activated protein kinase kinase 7	0.122
map2k4b	mitogen-activated protein kinase kinase 4b	0.116
mapk8b	mitogen-activated protein kinase 8b	0.110
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.106
wnt5a	wingless-type MMTV integration site family, member 5a	0.106	Zebrafish
lhx5	LIM homeobox 5	0.095
ism1	isthmin 1	0.093
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.090
vsx1	visual system homeobox 1 homolog, chx10-like	0.087
chrna4	cholinergic receptor, nicotinic, alpha 4	0.085
tbx16	T-box gene 16	0.085
map2k4a	mitogen-activated protein kinase kinase 4a	0.084
sim1a	single-minded homolog 1a (Drosophila)	0.084
fgf4	fibroblast growth factor 4	0.083
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.081
dusp6	dual specificity phosphatase 6	0.079
ntn1b	netrin 1b	0.079
bon	bonnie and clyde	0.079
gbx1	gastrulation brain homeobox 1	0.079
si:dkey-273o13.1	si:dkey-273o13.1	0.076
oprk1	opioid receptor, kappa 1	0.076
sox11b	SRY-box containing gene 11b	0.075
glcea	glucuronyl C5-epimerase a	0.072
sult1st4	sulfotransferase family 1, cytosolic sulfotransferase 4	0.072
tfpi2	tissue factor pathway inhibitor 2	0.072
wnt11	wingless-type MMTV integration site family, member 11	0.072	Zebrafish
mapk14a	mitogen-activated protein kinase 14a	0.072
bmp1a	bone morphogenetic protein 1a	0.071
spaw	southpaw	0.070
has3	hyaluronan synthase 3	0.069
frem3	Fras1 related extracellular matrix 3	0.068
grem2	gremlin 2, cysteine knot superfamily	0.068
znf711	zinc finger protein 711	0.065
smad9	MAD homolog 9 (Drosophila)	0.064
comta	catechol-O-methyltransferase a	0.063
csnk1da	casein kinase 1, delta a	0.063
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.063	Zebrafish
her5	hairy-related 5	0.062
fgf6a	fibroblast growth factor 6a	0.061
gli2b	GLI-Kruppel family member GLI2b	0.061
dab1b	disabled homolog 1b (Drosophila)	0.061
hnf1bb	HNF1 homeobox Bb	0.060
flh	floating head	0.058
pax7a	paired box gene 7a	0.058
zgc:171802	zgc:171802	0.058
mxtx2	mix-type homeobox gene 2	0.057
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.056
setd8a	SET domain containing (lysine methyltransferase) 8a	0.054
cryaa	crystallin, alpha A	0.053
fgf3	fibroblast growth factor 3	0.052
marcksb	myristoylated alanine rich protein kinase C substrate b	0.050
sp2	sp2 transcription factor	0.049
LOC566708	FL cytokine receptor-like	0.049
epb4.1l4	erythrocyte protein band 4.1-like 4	0.049
tcf21	transcription factor 21	0.048
emx1	empty spiracles homeobox 1	0.047
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.046
sfrp1a	secreted frizzled-related protein 1a	0.045
foxb1.2	forkhead box B1.2	0.044
zbtb4	zinc finger and BTB domain containing 4	0.044
wtap	Wilms tumor 1 associated protein	0.044
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.044
osr2	odd-skipped related 2 (Drosophila)	0.044
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.042
oprm1	opioid receptor, mu 1	0.042
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.042
snai1b	snail homolog 1b (Drosophila)	0.042
ihha	Indian hedgehog homolog a	0.042
hoxa13b	homeo box A13b	0.041
ndr2	nodal-related 2	0.041
lft1	lefty1	0.041
nkx3.2	NK3 homeobox 2	0.040
satb2	SATB homeobox 2	0.040
si:dkey-236e20.2	si:dkey-236e20.2	0.038
oprd1a	opioid receptor, delta 1a	0.038
og9x	OG9 homeobox gene	0.038
lrmp	lymphoid-restricted membrane protein	0.037
hapln1a	hyaluronan and proteoglycan link protein 1a	0.037
myf6	myogenic factor 6	0.037
mapk12	mitogen-activated protein kinase 12	0.037
fas	Fas (TNF receptor superfamily, member 6)	0.037
kop	askopos	0.037
glra4a	glycine receptor, alpha 4a	0.037
notum3	notum 3	0.037
vent	ventral expressed homeobox	0.035
stat1b	signal transducer and activator of transcription 1b	0.035
osr1	odd-skipped related 1 (Drosophila)	0.034
glra1	glycine receptor, alpha 1	0.034
hoxa2b	homeo box A2b	0.034
sass6	spindle assembly 6 homolog (C. elegans)	0.033
sox17	SRY-box containing gene 17	0.033
runx2b	runt-related transcription factor 2b	0.033
ved	ventrally expressed dharma/bozozok antagonist	0.033
sp5l	Sp5 transcription factor-like	0.032
lft2	lefty2	0.032
neurod4	neurogenic differentiation 4	0.032
fbln1	fibulin 1	0.032
ndr1	nodal-related 1	0.032
bmp7a	bone morphogenetic protein 7a	0.032
oep	one-eyed pinhead	0.032
sb:cb81	sb:cb81	0.031
scube2	signal peptide, CUB domain, EGF-like 2	0.031
pax8	paired box gene 8	0.030
her3	hairy-related 3	0.030
lhx1b	LIM homeobox 1b	0.030	Mouse
rargb	retinoic acid receptor, gamma b	0.030
sox4b	SRY-box containing gene 4b	0.029
si:ch211-173o4.2	si:ch211-173o4.2	0.029
oxtl	oxytocin-like	0.029
lhx2a	LIM homeobox 2a	0.029
pglyrp2	peptidoglycan recognition protein 2	0.028
smad3b	MAD, mothers against decapentaplegic homolog 3b (Drosophila)	0.028
pth2	parathyroid hormone 2	0.028
sim2	single-minded homolog 2 (Drosophila)	0.028
gyltl1b	glycosyltransferase-like 1b	0.028
LOC100359374	BCL-WAV	0.028
bmp4	bone morphogenetic protein 4	0.028
mapk6	mitogen-activated protein kinase 6	0.028
rnd1l	Rho family GTPase 1 like	0.028
dbx1a	developing brain homeobox 1a	0.028
hlxb9lb	homeo box HB9 like b	0.028
buc	bucky ball	0.027
eve1	even-skipped-like1	0.027
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.027
bhlhe41	basic helix-loop-helix family, member e41	0.027
lzts2a	leucine zipper, putative tumor suppressor 2a	0.027
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.026
twist1b	twist1b	0.026
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.026
gpr173	G-protein coupled receptor 173	0.026
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.026
mc5ra	melanocortin 5a receptor	0.025
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.025
lmo1	LIM domain only 1	0.025
mapk4	mitogen-activated protein kinase 4	0.024
tbx18	T-box 18	0.024
rnf41	ring finger protein 41	0.024
wif1	wnt inhibitory factor 1	0.024
cpa2	carboxypeptidase A2 (pancreatic)	0.024
rest	RE1-silencing transcription factor	0.024
gdf6b	growth differentiation factor 6b	0.024
epha4b	eph receptor A4b	0.024
foxd5	forkhead box D5	0.023
frzb	frizzled-related protein	0.023
onecutl	one cut domain, family member, like	0.022
odz4	odd Oz/ten-m homolog 4	0.022
perp	PERP, TP53 apoptosis effector	0.022
wnt11r	wingless-type MMTV integration site family, member 11, related	0.022	Zebrafish
esrra	estrogen-related receptor alpha	0.022
pdlim3b	PDZ and LIM domain 3b	0.021
smarce1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.021
tbx2a	T-box gene 2a	0.021
sulf1	sulfatase 1	0.021
cdx4	caudal type homeo box transcription factor 4	0.020
elk4	ELK4, ETS-domain protein	0.020
im:7162646	im:7162646	0.020
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.020
veph	ventricular zone expressed PH domain protein	0.020
etv2	ets variant gene 2	0.020
LOC566570	solute carrier family 22 member 6-like	0.020
nkx1.2la	NK1 transcription factor related 2-like,a	0.020
ap2a1	adaptor-related protein complex 2, alpha 1 subunit	0.019
ppp1r3ca	protein phosphatase 1, regulatory (inhibitor) subunit 3Ca	0.019
hoxc4a	homeo box C4a	0.019
wnt8a	wingless-type MMTV integration site family, member 8a	0.019
cnr1	cannabinoid receptor 1	0.019
twist1a	twist1a	0.019
tob1a	transducer of ERBB2, 1a	0.018
ier2	immediate early response 2	0.018
im:7165141	im:7165141	0.018
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.018
srsf4	serine/arginine-rich splicing factor 4	0.018
si:dkeyp-15g12.1	si:dkeyp-15g12.1	0.018
fbxl14b	F-box and leucine-rich repeat protein 14b	0.018
sox3	SRY-box containing gene 3	0.017
pcdh18b	protocadherin 18b	0.017
barhl2	BarH-like 2	0.017
aplnrb	apelin receptor b	0.017
ldb2b	LIM-domain binding factor 2b	0.017
si:ch1073-351m12.1	si:ch1073-351m12.1	0.017
glis3	GLIS family zinc finger 3	0.017
chrnb3a	cholinergic receptor, nicotinic, beta polypeptide 3a	0.016
nkd1	naked cuticle homolog 1 (Drosophila)	0.016
mesp2	mesoderm posterior 2 homolog (mouse)	0.016
hspb1	heat shock protein, alpha-crystallin-related, 1	0.016
pkd2	polycystic kidney disease 2	0.016
myf5	myogenic factor 5	0.016
hoxb5a	homeo box B5a	0.016
dmrt3a	doublesex and mab-3 related transcription factor 3a	0.016
sept7b	septin 7b	0.016
csad	cysteine sulfinic acid decarboxylase	0.016
trim3a	tripartite motif-containing 3a	0.016
evx2	even-skipped homeobox 2	0.016
klf4a	Kruppel-like transcription factor 4a	0.016
msxa	muscle segment homeobox A	0.016
limk1	LIM domain kinase 1	0.016
mga	MAX gene associated	0.015
tjp2a	tight junction protein 2a (zona occludens 2)	0.015
kpna4	karyopherin alpha 4 (importin alpha 3)	0.015
nnr	nanor	0.015
itgav	integrin, alpha V	0.015
dab1a	disabled homolog 1a (Drosophila)	0.015
fes	feline sarcoma oncogene	0.015
her12	hairy-related 12	0.015
hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.015
foxa2	forkhead box A2	0.015
fzd10	frizzled homolog 10	0.015
tbx24	T-box 24	0.015
ihhb	Indian hedgehog homolog b	0.014
pcdh8	protocadherin 8	0.014
stac3	SH3 and cysteine rich domain 3	0.014
rln3a	relaxin 3a	0.014
spsb4a	splA/ryanodine receptor domain and SOCS box containing 4a	0.014
wls	wntless homolog (Drosophila)	0.014
lhx3	LIM homeobox 3	0.014
nkd2	naked cuticle homolog 2 and naked 2a	0.014
gngt2b	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b	0.014
pou5f1	POU domain, class 5, transcription factor 1	0.014
rfng	radical fringe homolog (Drosophila)	0.014
axin1	axin 1	0.014
gc2	guanylyl cyclase 2	0.014
chrm2a	cholinergic receptor, muscarinic 2a	0.013
hoxa9a	homeo box A9a	0.013
wt1a	wilms tumor 1a	0.013
masp2	mannan-binding lectin serine peptidase 2	0.013
bactin2	bactin2	0.013
mapk7	mitogen-activated protein kinase 7	0.013
tph1b	tryptophan hydroxylase 1b	0.013
sfrp5	secreted frizzled-related protein 5	0.013
dmbx1a	diencephalon/mesencephalon homeobox 1a	0.013
cbx2	chromobox homolog 2 (Drosophila Pc class)	0.013
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.013
fbxl14a	F-box and leucine-rich repeat protein 14a	0.013
araf	v-raf murine sarcoma 3611 viral oncogene homolog	0.013
gle1	GLE1 RNA export mediator homolog (yeast)	0.013
slc10a2	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	0.013
cdkl1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.013
nkx2.2a	NK2 transcription factor related 2a	0.013
her11	hairy-related 11	0.013
hoxd13a	homeo box D13a	0.013
ptch2	patched 2	0.013
nog2	noggin 2	0.013
hoxb2a	homeo box B2a	0.013
exorh	extra-ocular rhodopsin	0.013
hoxa1a	homeo box A1a	0.013
csnk1db	casein kinase 1, delta b	0.013
ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.012
her1	hairy-related 1	0.012
hoxd11a	homeo box D11a	0.012
msnb	moesin b	0.012
mbd3a	methyl-CpG binding domain protein 3a	0.012
bcl2l10	BCL2-like 10 (apoptosis facilitator)	0.012
gmcl1	germ cell-less homolog 1 (Drosophila)	0.012
barx2	BarH-like homeobox 2	0.012
amotl2a	angiomotin like 2a	0.012
pggt1b	protein geranylgeranyltransferase type I, beta subunit	0.012
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.012
tfap2b	transcription factor AP-2 beta	0.012
shhb	sonic hedgehog b	0.012
cryaba	crystallin, alpha B, a	0.012
ephb4b	eph receptor B4b	0.012
glceb	glucuronyl C5-epimerase b	0.012
hoxd10a	homeo box D10a	0.012
limk2	LIM domain kinase 2	0.012
cx44.1	connexin 44.1	0.012
robo1	roundabout homolog 1	0.012
spast	spastin	0.012
ddx42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42	0.012
npy4r	neuropeptide Y receptor Y4	0.012
spsb1	splA/ryanodine receptor domain and SOCS box containing 1	0.012
kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.012
barx1	BarH-like homeobox 1	0.012
wu:fc51d09	wu:fc51d09	0.011
mapk15	mitogen-activated protein kinase 15	0.011
runx1	runt-related transcription factor 1	0.011
pdlim7	PDZ and LIM domain 7	0.011
ins	preproinsulin	0.011
lrrc50	leucine rich repeat containing 50	0.011
numbl	numb homolog (Drosophila)-like	0.011
cables1	Cdk5 and Abl enzyme substrate 1	0.011
foxj1b	forkhead box J1b	0.011
bty	bloodthirsty	0.011
dag1	dystroglycan 1	0.011
zgc:113210	zgc:113210	0.011
chrnb3b	cholinergic receptor, nicotinic, beta polypeptide 3b	0.011
hoxc1a	homeo box C1a	0.011
sf1	splicing factor 1	0.011
gata4	GATA-binding protein 4	0.011
or115-10	odorant receptor, family F, subfamily 115, member 10	0.011
vax2	ventral anterior homeobox 2	0.011
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.011
atoh1a	atonal homolog 1a	0.011
msxc	muscle segment homeobox C	0.011
irf6	interferon regulatory factor 6	0.011
npas2	neuronal PAS domain protein 2	0.010
zgc:111944	zgc:111944	0.010
cyb5d1	cytochrome b5 domain containing 1	0.010
zgc:171495	zgc:171495	0.010
hmx3	homeo box (H6 family) 3	0.010
chpf	chondroitin polymerizing factor	0.010
gatsl2	GATS protein-like 2	0.010
mapk1	mitogen-activated protein kinase 1	0.010