IMP: Integrative Multi-species Prediction

Danio rerio

15 genes annotated in zebrafish

Multi-species View

auditory receptor cell differentiation

GO:0042491

The process in which a relatively unspecialized cell acquires specialized features of an auditory hair cell.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "auditory receptor cell differentiation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "auditory receptor cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
tbx1	T-box 1	0.987
pax2a	paired box gene 2a	0.986
dla	deltaA	0.981	Zebrafish Mouse
cdh23	cadherin-like 23	0.966
dlx2a	distal-less homeobox gene 2a	0.918
dlb	deltaB	0.892	Zebrafish
dlc	deltaC	0.888	Zebrafish
fgf8a	fibroblast growth factor 8 a	0.886
neurog1	neurogenin 1	0.776	Zebrafish
atoh1b	atonal homolog 1b	0.737
eya1	eyes absent homolog 1	0.678
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.657
bmp4	bone morphogenetic protein 4	0.589
lhx2b	LIM homeobox 2b	0.571	Zebrafish
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.540
pitx3	paired-like homeodomain transcription factor 3	0.524
mib	mind bomb	0.501
dlx3b	distal-less homeobox gene 3b	0.471
bmp2b	bone morphogenetic protein 2b	0.450
jag1b	jagged 1b	0.441
emx3	empty spiracles homeobox 3	0.430
dlx2b	distal-less homeobox gene 2b	0.406	Zebrafish
dlx4a	distal-less homeobox gene 4a	0.394	Zebrafish
sox9a	SRY-box containing gene 9a	0.379
fgf3	fibroblast growth factor 3	0.373
wls	wntless homolog (Drosophila)	0.349
notch3	notch homolog 3	0.342
notch1a	notch homolog 1a	0.341	Mouse
dlx6a	distal-less homeobox gene 6a	0.311	Zebrafish
dlx1a	distal-less homeobox gene 1a	0.299	Zebrafish
jag2	jagged 2	0.292	Zebrafish Mouse
ift88	intraflagellar transport 88 homolog	0.268
hnf1ba	HNF1 homeobox Ba	0.266
isl1	islet1	0.253	Zebrafish
her6	hairy-related 6	0.235
osr2	odd-skipped related 2 (Drosophila)	0.227
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.212
otpb	orthopedia homolog b	0.207
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.204
prox1	prospero-related homeobox gene 1	0.201
kdrl	kinase insert domain receptor like	0.183
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.179
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.178
atoh1a	atonal homolog 1a	0.174
crb2a	crumbs homolog 2a	0.165
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.157
hhex	hematopoietically expressed homeobox	0.147
eve1	even-skipped-like1	0.146
hhip	hedgehog interacting protein	0.145
epb4.1l4	erythrocyte protein band 4.1-like 4	0.144
ptch1	patched 1	0.139
otx2	orthodenticle homolog 2	0.132
sox10	SRY-box containing gene 10	0.130
myf5	myogenic factor 5	0.130
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.128
eomesa	eomesodermin homolog a	0.118
ptf1a	pancreas specific transcription factor, 1a	0.115	Zebrafish
synj1	synaptojanin 1	0.111
prdm1a	PR domain containing 1a, with ZNF domain	0.106
eng2a	engrailed 2a	0.099
elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.090
gata5	GATA-binding protein 5	0.084
nkx3.2	NK3 homeobox 2	0.080
foxn4	forkhead box N4	0.079
evx1	even-skipped homeobox 1	0.076
barhl2	BarH-like 2	0.076
fgfr1a	fibroblast growth factor receptor 1a	0.075	Mouse
vangl2	vang-like 2 (van gogh, Drosophila)	0.075
hoxa2b	homeo box A2b	0.075
slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.074
pax8	paired box gene 8	0.073
dld	deltaD	0.069	Zebrafish Mouse
cdh2	cadherin 2, neuronal	0.068
ctnnd2b	catenin (cadherin-associated protein), delta 2b	0.066
th	tyrosine hydroxylase	0.065
myo7aa	myosin VIIAa	0.064
nxph1	neurexophilin 1	0.059
chrna6	cholinergic receptor, nicotinic, alpha 6	0.058
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.058
fzd8a	frizzled homolog 8a	0.058
hnf1bb	HNF1 homeobox Bb	0.057
myo6b	myosin VIb	0.057
tbx2b	T-box 2b	0.056
dlx5a	distal-less homeobox gene 5a	0.055	Zebrafish
neurod	neurogenic differentiation	0.054	Zebrafish
nkx2.1a	NK2 homeobox 1a	0.053
tgfb3	transforming growth factor, beta 3	0.053
shha	sonic hedgehog a	0.052
gli2a	GLI-Kruppel family member GLI2a	0.052
sim1a	single-minded homolog 1a (Drosophila)	0.052
insm1b	insulinoma-associated 1b	0.052
LOC567452	G protein-coupled receptor kinase 5-like	0.051
kitb	kit receptor b	0.051
chd	chordin	0.051
gpr126	G protein-coupled receptor 126	0.050
dlx4b	distal-less homeobox gene 4b	0.049
msxe	muscle segment homeobox E	0.048
itgav	integrin, alpha V	0.048
lrrc6	leucine rich repeat containing 6	0.047
fgf19	fibroblast growth factor 19	0.045
st8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.044
foxg1a	forkhead box G1a	0.044
unc45a	unc-45 homolog A (C. elegans)	0.044
atoh7	atonal homolog 7	0.043	Zebrafish
shhb	sonic hedgehog b	0.043
appl1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.043
oprd1b	opioid receptor, delta 1b	0.042
gata2a	GATA-binding protein 2a	0.042
barhl1.2	BarH-like 1.2	0.041
mab21l2	mab-21-like 2	0.041
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.040
insm1a	insulinoma-associated 1a	0.040
sox1a	SRY-box containing gene 1a	0.040
cc2d2a	coiled-coil and C2 domain containing 2A	0.039
gata1a	GATA binding protein 1a	0.039
six4b	sine oculis homeobox homolog 4b	0.039
pax2b	paired box gene 2b	0.038
tp63	tumor protein p63	0.038
gsc	goosecoid	0.037
olig2	oligodendrocyte lineage transcription factor 2	0.037
plcg1	phospholipase C, gamma 1	0.036
hapln1a	hyaluronan and proteoglycan link protein 1a	0.036
msxc	muscle segment homeobox C	0.036
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.036
fezf2	FEZ family zinc finger 2	0.035
wnt8a	wingless-type MMTV integration site family, member 8a	0.035
ap1b1	adaptor-related protein complex 1, beta 1 subunit	0.035
foxp2	forkhead box P2	0.035
ptch2	patched 2	0.035
tmie	transmembrane inner ear	0.035
neurod4	neurogenic differentiation 4	0.034	Zebrafish
six4a	sine oculis homeobox homolog 4a	0.034
fgf10a	fibroblast growth factor 10a	0.033
eng2b	engrailed 2b	0.033
fgf8b	fibroblast growth factor 8 b	0.033
foxa2	forkhead box A2	0.033
tal1	T-cell acute lymphocytic leukemia 1	0.032	Zebrafish
gro1	groucho 1	0.032
sema3aa	semaphorin 3aa	0.032
kif17	kinesin family member 17	0.031
slc17a8	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	0.030
hnf4a	hepatocyte nuclear factor 4, alpha	0.030
mecom	MDS1 and EVI1 complex locus	0.030
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.030
lef1	lymphocyte enhancer binding factor 1	0.029
gli1	GLI-Kruppel family member 1	0.029
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.029
dcc	deleted in colorectal carcinoma	0.028
gro2	groucho 2	0.028
tbx20	T-box 20	0.027
fgfr4	fibroblast growth factor receptor 4	0.027
gbx2	gastrulation brain homeo box 2	0.027
her12	hairy-related 12	0.026	Mouse
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.026
ntla	no tail a	0.026
six2a	sine oculis-related homeobox 2a	0.025
scn1bb	sodium channel, voltage-gated, type I, beta b	0.025
fli1a	friend leukemia integration 1a	0.025
eml2	echinoderm microtubule associated protein like 2	0.025
rela	v-rel reticuloendotheliosis viral oncogene homolog A	0.025
pax6b	paired box gene 6b	0.025
mpz	myelin protein zero	0.024
gata3	GATA-binding protein 3	0.024
fgf20a	fibroblast growth factor 20a	0.024
dbx1a	developing brain homeobox 1a	0.023
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.023
scube2	signal peptide, CUB domain, EGF-like 2	0.023
pax6a	paired box gene 6a	0.022
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.022	Mouse
adcyap1r1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	0.022
six1b	sine oculis homeobox homolog 1b	0.022
her15.1	hairy and enhancer of split-related 15.1	0.021	Mouse
runx1	runt-related transcription factor 1	0.021
bmp2a	bone morphogenetic protein 2a	0.021
traf4a	tnf receptor-associated factor 4a	0.021
pou4f1	POU domain, class 4, transcription factor 1	0.021
her4.2	hairy-related 4.2	0.021	Mouse
arl13b	ADP-ribosylation factor-like 13b	0.020
opa3	optic atrophy 3	0.020
pld1a	phospholipase D1a	0.020
col2a1a	collagen type II, alpha-1a	0.020
penkb	proenkephalin b	0.019
notch2	notch homolog 2	0.019
gyltl1b	glycosyltransferase-like 1b	0.019
celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	0.019
ndr2	nodal-related 2	0.019
foxc1a	forkhead box C1a	0.019
atp6v1ba	ATPase, H+ transporting, lysosomal, V1 subunit B, member a	0.019
atp6v1b2	ATPase, H+ transporting, lysosomal V1 subunit B2	0.019
thsd7a	thrombospondin, type I, domain containing 7A	0.019
lhx1a	LIM homeobox 1a	0.018	Zebrafish
ildr1b	immunoglobulin-like domain containing receptor 1b	0.018
ush1c	Usher syndrome 1C (autosomal recessive, severe)	0.018
foxa3	forkhead box A3	0.018
dusp6	dual specificity phosphatase 6	0.018
tbr1b	T-box, brain, 1b	0.018
lhx6	LIM homeobox 6	0.018	Zebrafish
itgb3b	integrin beta 3b	0.018
fabp2	fatty acid binding protein 2, intestinal	0.017
coe2	coe2	0.017
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.017
arx	aristaless related homeobox	0.017
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.016
olig4	oligodendrocyte transcription factor 4	0.016
igfbp3	insulin-like growth factor binding protein 3	0.016
sp7	Sp7 transcription factor	0.016
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.016
sall4	sal-like 4 (Drosophila)	0.015
meis2.1	myeloid ecotropic viral integration site 2.1	0.015
lhx1b	LIM homeobox 1b	0.015	Zebrafish
crb3b	crumbs homolog 3b	0.015
krt4	keratin 4	0.015
pcdh10b	protocadherin 10b	0.015
barhl1.1	BarH-like 1.1	0.015
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.015
alcamb	activated leukocyte cell adhesion molecule b	0.015
phox2b	paired-like homeobox 2b	0.015
flr	fleer	0.014
scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.014
p2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.014
dll4	delta-like 4 (Drosophila)	0.014	Zebrafish
hoxb1b	homeo box B1b	0.014
gmds	GDP-mannose 4,6-dehydratase	0.014
phox2a	paired-like homeobox 2a	0.014
barx1	BarH-like homeobox 1	0.014
tyr	tyrosinase	0.014
sox3	SRY-box containing gene 3	0.014
fzd7b	frizzled homolog 7b	0.014
osr1	odd-skipped related 1 (Drosophila)	0.014
fyna	FYN oncogene related to SRC, FGR, YES a	0.014
vcana	versican a	0.014
wnt3	wingless-type MMTV integration site family, member 3	0.014
dzip1	DAZ interacting protein 1	0.013
met	met proto-oncogene (hepatocyte growth factor receptor)	0.013
efnb2a	ephrin B2a	0.013
pou3f3a	POU class 3 homeobox 3a	0.013
slc38a3	solute carrier family 38, member 3	0.013
nkx2.1b	NK2 homeobox 1b	0.013
crb1	crumbs homolog 1 (Drosophila)	0.013
nkx2.5	NK2 transcription factor related 5	0.013
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.013
twist1b	twist1b	0.013
nkx2.3	NK2 transcription factor related 3	0.013
traf3ip1	TNF receptor-associated factor 3 interacting protein 1	0.013
epcam	epithelial cell adhesion molecule	0.013
msgn1	mesogenin 1	0.012
pvrl1b	poliovirus receptor-related 1b	0.012
fgfr2	fibroblast growth factor receptor 2	0.012
clock	clock	0.012
cap1	Cap1 CAP, adenylate cyclase-associated protein 1	0.012
tgfb2	transforming growth factor, beta 2	0.012
robo3	roundabout homolog 3	0.012
her1	hairy-related 1	0.012
dpysl2b	dihydropyrimidinase-like 2b	0.012
etv2	ets variant gene 2	0.012
isl2a	islet2a	0.012	Zebrafish
cacna1da	calcium channel, voltage-dependent, L type, alpha 1D subunit, a	0.012
adcyap1b	adenylate cyclase activating polypeptide 1b	0.012
stap2a	signal transducing adaptor family member 2a	0.012
prkci	protein kinase C, iota	0.012
slc4a1b	solute carrier family 4, anion exchanger, member 1b	0.012
gdnf	glial cell derived neurotrophic factor	0.012
syne2b	spectrin repeat containing, nuclear envelope 2b	0.012
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.012
fgf13b	fibroblast growth factor 13b	0.012
tbx5a	T-box 5a	0.011
hoxb5a	homeo box B5a	0.011
tbx16	T-box gene 16	0.011
sox19a	SRY-box containing gene 19a	0.011
pitx2	paired-like homeodomain transcription factor 2	0.011
evpl	envoplakin	0.011
tal2	T-cell acute lymphocytic leukemia 2	0.011
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.011
hoxb4a	homeo box B4a	0.011
cnr1	cannabinoid receptor 1	0.011
wt1a	wilms tumor 1a	0.011
cdh6	cadherin 6	0.011
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.011
adh5	alcohol dehydrogenase 5	0.011
neurod6a	neurogenic differentiation 6a	0.011
sod2	superoxide dismutase 2, mitochondrial	0.011
chrnb3a	cholinergic receptor, nicotinic, beta polypeptide 3a	0.011
pcdh15a	protocadherin 15a	0.011	Mouse
supt6h	suppressor of Ty 6 homolog	0.011
runx2a	runt-related transcription factor 2a	0.011
otx5	orthodenticle homolog 5	0.011
oc90	otoconin 90	0.011
six3a	sine oculis homeobox homolog 3a	0.010
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.010
ppp3ccb	protein phosphatase 3, catalytic subunit, gamma isozyme, b	0.010
pax9	paired box gene 9	0.010
pcdh17	protocadherin 17	0.010
h1m	linker histone H1M	0.010
cdx4	caudal type homeo box transcription factor 4	0.010
pou4f3	POU domain, class 4, transcription factor 3	0.010	Mouse
hoxc4a	homeo box C4a	0.010
wu:fi18a01	wu:fi18a01	0.010
emx2	empty spiracles homeobox 2	0.010
hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase	0.010
sox21b	SRY-box containing gene 21 b	0.010
ift172	intraflagellar transport 172	0.010