IMP: Integrative Multi-species Prediction

Danio rerio

116 genes annotated in zebrafish

apoptotic process

A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "apoptotic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
hand2	heart and neural crest derivatives expressed transcript 2	0.955	Mouse Fly
tbx1	T-box 1	0.863	Mouse
gli1	GLI-Kruppel family member 1	0.786	Worm
fgf8a	fibroblast growth factor 8 a	0.777	Mouse
evx1	even-skipped homeobox 1	0.771
shha	sonic hedgehog a	0.769	Mouse
sox2	SRY-box containing gene 2	0.763	Human
flt4	fms-related tyrosine kinase 4	0.751	Human Zebrafish Fly
tbx20	T-box 20	0.719
gata3	GATA-binding protein 3	0.703	Human Zebrafish Mouse
fgfr1a	fibroblast growth factor receptor 1a	0.702	Mouse
ptch2	patched 2	0.698	Fly
th	tyrosine hydroxylase	0.695
rpl19	ribosomal protein L19	0.680	Worm
tp53	tumor protein p53	0.654
csnk1da	casein kinase 1, delta a	0.647	Fly
baxa	bcl2-associated X protein, a	0.644
plcg1	phospholipase C, gamma 1	0.626	Worm
runx2b	runt-related transcription factor 2b	0.623	Fly
efnb2a	ephrin B2a	0.616
hspa5	heat shock protein 5	0.616	Human Worm
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.612
nrg2a	neuregulin 2a	0.611
bmp2b	bone morphogenetic protein 2b	0.608	Human
kita	kit receptor a	0.608
rpsa	ribosomal protein SA	0.595	Worm
sox3	SRY-box containing gene 3	0.591
col2a1a	collagen type II, alpha-1a	0.569	Mouse
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.564
bmp4	bone morphogenetic protein 4	0.562	Human Mouse Rat
dlx5a	distal-less homeobox gene 5a	0.558
fgf10a	fibroblast growth factor 10a	0.555	Zebrafish Mouse
ndufv1	NADH dehydrogenase (ubiquinone) flavoprotein 1	0.552
spry4	sprouty (Drosophila) homolog 4	0.546
cav1	caveolin 1	0.521	Human Mouse
tshb	thyroid stimulating hormone, beta subunit	0.509
sema3aa	semaphorin 3aa	0.505	Rat
pitx3	paired-like homeodomain transcription factor 3	0.489
egr1	early growth response 1	0.485	Mouse Rat
bbc3	BCL2 binding component 3	0.479
vcana	versican a	0.466
sox32	SRY-box containing gene 32	0.463	Fly
bcl2l1	bcl2-like 1	0.461
klf4a	Kruppel-like transcription factor 4a	0.460
bdnf	brain-derived neurotrophic factor	0.457	Mouse
gadd45aa	growth arrest and DNA-damage-inducible, alpha, a	0.445	Human
ptf1a	pancreas specific transcription factor, 1a	0.435
gli2a	GLI-Kruppel family member GLI2a	0.419	Worm
wnt11r	wingless-type MMTV integration site family, member 11, related	0.418	Mouse
traf4a	tnf receptor-associated factor 4a	0.410	Fly
ctsl1b	cathepsin L, 1 b	0.410
rpl13	ribosomal protein L13	0.405	Worm
notch1a	notch homolog 1a	0.404	Human Mouse
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.393
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.384
notch2	notch homolog 2	0.382	Mouse
myod1	myogenic differentiation 1	0.376
atp6v1ba	ATPase, H+ transporting, lysosomal, V1 subunit B, member a	0.364	Worm
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.363	Human Mouse Fly
piwil1	piwi-like 1 (Drosophila)	0.360
rpl35	ribosomal protein L35	0.360	Worm
gbx2	gastrulation brain homeo box 2	0.351
cnr1	cannabinoid receptor 1	0.350	Rat
rpl18a	ribosomal protein L18a	0.349
otpa	orthopedia homolog a	0.348
lhx1a	LIM homeobox 1a	0.347
pax2a	paired box gene 2a	0.347	Mouse
col14a1	collagen, type XIV, alpha 1	0.339
tcf12	transcription factor 12	0.338
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.337	Mouse
rpl36a	ribosomal protein L36A	0.337
khdrbs1a	KH domain containing, RNA binding, signal transduction associated 1a	0.337	Fly
tal1	T-cell acute lymphocytic leukemia 1	0.327
mcl1a	myeloid cell leukemia sequence 1a	0.326
fgfr3	fibroblast growth factor receptor 3	0.323	Human Mouse
plxnb2a	plexin b2a	0.317
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.312
zgc:65861	zgc:65861	0.311
pcna	proliferating cell nuclear antigen	0.309
foxp2	forkhead box P2	0.306
aplnrb	apelin receptor b	0.303
notch3	notch homolog 3	0.298
rps2	ribosomal protein S2	0.296
per2	period homolog 2 (Drosophila)	0.295
sox11a	SRY-box containing gene 11a	0.289
pea3	ETS-domain transcription factor pea3	0.288
kdrl	kinase insert domain receptor like	0.284	Zebrafish Fly
nav3	neuron navigator 3	0.284
tyr	tyrosinase	0.283
atp6v0ca	ATPase, H+ transporting, lysosomal, V0 subunit c, a	0.281	Worm
zfand5a	zinc finger, AN1-type domain 5a	0.280
vegfaa	vascular endothelial growth factor Aa	0.276
eif4e	eukaryotic translation initiation factor 4e	0.275
nrg1	neuregulin 1	0.270	Human
rps15a	ribosomal protein S15a	0.267
nr0b1	nuclear receptor subfamily 0, group B, member 1	0.266
vdra	vitamin D receptor a	0.266
cyp1b1	cytochrome P450, family 1, subfamily B, polypeptide 1	0.264	Mouse
adrb2a	adrenergic receptor, beta 2a	0.263
faua	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a	0.262
mki67ip	mki67 (FHA domain) interacting nucleolar phosphoprotein (human)	0.262
odc1	ornithine decarboxylase 1	0.259
wnt4a	wingless-type MMTV integration site family, member 4a	0.257	Mouse
kdr	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.256	Human Zebrafish Fly
rarga	retinoic acid receptor gamma a	0.254	Mouse
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.253
rplp0	ribosomal protein, large, P0	0.250	Worm
neo1	neogenin 1	0.250
ef1a	elongation factor 1-alpha	0.249	Worm
emx3	empty spiracles homeobox 3	0.248
foxo3b	forkhead box O3b	0.244	Human Zebrafish Mouse Worm
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.242
pax7a	paired box gene 7a	0.242
nkx2.2a	NK2 transcription factor related 2a	0.241
bmp2a	bone morphogenetic protein 2a	0.240	Human
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.239
lpp	LIM domain containing preferred translocation partner in lipoma	0.239
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.238
tp73	tumor protein p73	0.237	Human Zebrafish Mouse Worm Fly
dusp6	dual specificity phosphatase 6	0.236	Human
sox9a	SRY-box containing gene 9a	0.235	Human Mouse
hmgb1a	high-mobility group box 1a	0.233
cct7	chaperonin containing TCP1, subunit 7 (eta)	0.232	Worm
met	met proto-oncogene (hepatocyte growth factor receptor)	0.231
esr1	estrogen receptor 1	0.229	Mouse Rat
esr2a	estrogen receptor 2a	0.228	Mouse Rat
tgfb3	transforming growth factor, beta 3	0.228	Mouse Rat
rpl9	ribosomal protein L9	0.227
gata6	GATA-binding protein 6	0.226
celf1	cugbp, Elav-like family member 1	0.226	Worm
ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.226
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.225	Mouse
gnb2l1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	0.224	Human
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.223	Human Mouse Fly
runx1	runt-related transcription factor 1	0.222
ca8	carbonic anhydrase VIII	0.222
atp6v1g1	ATPase, H+ transporting, V1 subunit G isoform 1	0.221	Worm
trpv4	transient receptor potential cation channel, subfamily V, member 4	0.220
ckbb	creatine kinase, brain b	0.215
ran	ras-related nuclear protein	0.215	Worm
tbx18	T-box 18	0.214
copa	coatomer protein complex, subunit alpha	0.214	Worm
rpl7a	ribosomal protein L7a	0.212
pdia5	protein disulfide isomerase family A, member 5	0.211
sulf1	sulfatase 1	0.210
bactin2	bactin2	0.210	Worm
dlb	deltaB	0.209
dkk1b	dickkopf 1b	0.208
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.206
wu:fv91b12	wu:fv91b12	0.206
ptena	phosphatase and tensin homolog A	0.206	Mouse Fly
atp6v1h	ATPase, H+ transporting, lysosomal, V1 subunit H	0.205
fzd7a	frizzled homolog 7a	0.201
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.200	Human Mouse Worm
rxrga	retinoid x receptor, gamma a	0.198
cse1l	chromosome segregation 1-like (S. cerevisiae)	0.198
nrp2b	neuropilin 2b	0.198
prpf8	pre-mRNA processing factor 8	0.197
sox5	SRY-box containing gene 5	0.196
cpsf1	cleavage and polyadenylation specific factor 1	0.195
krml2.2	Kreisler (mouse) maf-related leucine zipper homolog 2.2	0.194
kif23	kinesin family member 23	0.194
aars	alanyl-tRNA synthetase	0.194	Mouse
tuba1l	tubulin, alpha 1, like	0.193	Zebrafish
frem3	Fras1 related extracellular matrix 3	0.192
itgb1b	integrin, beta 1b	0.191	Human Worm
elk4	ELK4, ETS-domain protein	0.191
wnt10a	wingless-type MMTV integration site family, member 10a	0.191
bnc2	basonuclin 2	0.191
slit3	slit (Drosophila) homolog 3	0.189	Human
myog	myogenin	0.189
chd	chordin	0.189
gpr126	G protein-coupled receptor 126	0.188
cad	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.187
rpl28	ribosomal protein L28	0.186
cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.185
ahsa1l	AHA1, activator of heat shock protein ATPase homolog 1, like	0.185
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.183
alcamb	activated leukocyte cell adhesion molecule b	0.183
mvp	major vault protein	0.182
mcl1b	myeloid cell leukemia sequence 1b	0.182
rpl21	ribosomal protein L21	0.182	Worm
nap1l1	nucleosome assembly protein 1, like 1	0.181
eif3g	eukaryotic translation initiation factor 3, subunit G	0.181
atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.181
cdc26	cell division cycle 26 homolog	0.180
sfrp1a	secreted frizzled-related protein 1a	0.179	Human Mouse
abcf1	ATP-binding cassette, sub-family F (GCN20), member 1	0.179
npm1	nucleophosmin 1	0.177	Human
ube2i	ubiquitin-conjugating enzyme E2I	0.177	Worm
tie1	endothelium-specific receptor tyrosine kinase 1	0.176
otud5a	OTU domain containing 5a	0.175
clock	clock	0.175
gata1a	GATA binding protein 1a	0.174
zgc:73328	zgc:73328	0.174
csnk1a1	casein kinase 1, alpha 1	0.173	Worm
zgc:64133	zgc:64133	0.172	Fly
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.172
foxi1	forkhead box I1	0.171
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.171	Rat
jag1a	jagged 1a	0.170
arf5	ADP-ribosylation factor 5	0.170
bmper	BMP binding endothelial regulator	0.170
zgc:85866	zgc:85866	0.170	Mouse
wt1a	wilms tumor 1a	0.169	Human Mouse
rpa1	replication protein A1	0.169
znf703	zinc finger protein 703	0.168
hoxd4a	homeo box D4a	0.168
epb4.1l4	erythrocyte protein band 4.1-like 4	0.167
esco2	establishment of cohesion 1 homolog 2	0.167
lef1	lymphocyte enhancer binding factor 1	0.166	Human Mouse Worm
lhx2b	LIM homeobox 2b	0.166
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.166	Worm
csnk1db	casein kinase 1, delta b	0.166	Fly
mmp9	matrix metalloproteinase 9	0.166	Mouse
eef1b2	eukaryotic translation elongation factor 1 beta 2	0.165
myf5	myogenic factor 5	0.164
nup107	nucleoporin 107	0.164
rpl6	ribosomal protein L6	0.164
mga	MAX gene associated	0.164
sfrp5	secreted frizzled-related protein 5	0.163
rps12	ribosomal protein S12	0.163
atp1b1b	ATPase, Na+/K+ transporting, beta 1b polypeptide	0.163
pou1f1	POU domain, class 1, transcription factor 1	0.163
zgc:111961	zgc:111961	0.162
dlx2a	distal-less homeobox gene 2a	0.162
zdhhc8b	zinc finger, DHHC-type containing 8b	0.162
rps18	ribosomal protein S18	0.161
pou3f3a	POU class 3 homeobox 3a	0.159	Mouse
ahr2	aryl hydrocarbon receptor 2	0.158
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.158
pitx2	paired-like homeodomain transcription factor 2	0.158
tubg1	tubulin, gamma 1	0.157	Worm
ptch1	patched 1	0.157	Fly
ccna2	cyclin A2	0.157
wu:fb58e05	wu:fb58e05	0.156
wnt4b	wingless-type MMTV integration site family, member 4b	0.155
melk	maternal embryonic leucine zipper kinase	0.155	Human Mouse Worm
fgfr4	fibroblast growth factor receptor 4	0.154
cdc42	cell division cycle 42	0.154	Rat
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.153
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.153	Human
slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.153
nrp1a	neuropilin 1a	0.152	Mouse
rpl23a	ribosomal protein L23a	0.152	Worm
cct5	chaperonin containing TCP1, subunit 5 (epsilon)	0.150	Worm
bnip3lb	BCL2/adenovirus E1B interacting protein 3-like b	0.149
gsc	goosecoid	0.149
foxh1	forkhead box H1	0.149
barhl1.2	BarH-like 1.2	0.149
cct6a	chaperonin containing TCP1, subunit 6A (zeta 1)	0.148	Worm
ccnd1	cyclin D1	0.148
mt2	metallothionein 2	0.147	Mouse
sass6	spindle assembly 6 homolog (C. elegans)	0.147
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.147
nos1	nitric oxide synthase 1 (neuronal)	0.147	Rat
edn1	endothelin 1	0.146
cul1b	cullin 1b	0.146	Mouse Worm Fly
atoh1a	atonal homolog 1a	0.145	Mouse
sall4	sal-like 4 (Drosophila)	0.145
prmt1	protein arginine methyltransferase 1	0.145
hspd1	heat shock 60kD protein 1 (chaperonin)	0.144	Human
nkx2.5	NK2 transcription factor related 5	0.144
wnt5b	wingless-type MMTV integration site family, member 5b	0.144	Human Mouse
sars	seryl-tRNA synthetase	0.144
id3	inhibitor of DNA binding 3	0.144	Rat
cd63	Cd63 antigen	0.144
atoh1b	atonal homolog 1b	0.143	Mouse
arf2	ADP-ribosylation factor 2	0.143	Worm
ripk2	receptor-interacting serine-threonine kinase 2	0.143
rps11	ribosomal protein S11	0.142
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.142
robo1	roundabout homolog 1	0.142	Human
igf1rb	insulin-like growth factor 1b receptor	0.142
eif3d	eukaryotic translation initiation factor 3, subunit D	0.139	Worm
sip1	survival of motor neuron protein interacting protein 1	0.139
bcl2	B-cell leukemia/lymphoma 2	0.138
robo3	roundabout homolog 3	0.138
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.137
rspo1	R-spondin homolog (Xenopus laevis)	0.137
mib	mind bomb	0.137
apoeb	apolipoprotein Eb	0.137
tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.136
notch1b	notch homolog 1b	0.136	Human Mouse
hmgb2b	high-mobility group box 2b	0.136	Mouse
creb3l3l	cAMP responsive element binding protein 3-like 3 like	0.136	Worm
ptmaa	prothymosin, alpha a	0.136
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.135
foxa2	forkhead box A2	0.134	Fly
maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)	0.134
jun	jun proto-oncogene	0.134	Mouse Rat
pax8	paired box gene 8	0.134	Mouse
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.132
rac3a	ras-related C3 botulinum toxin substrate 3a (rho family, small GTP binding protein Rac3)	0.132
pknox1.2	pbx/knotted 1 homeobox 1.2	0.132
nog2	noggin 2	0.132
kif11	kinesin family member 11	0.132	Worm
rorca	RAR-related orphan receptor C a	0.131
pabpc1a	poly A binding protein, cytoplasmic 1 a	0.130
rbb4	retinoblastoma binding protein 4	0.130	Worm
rps29	ribosomal protein S29	0.130
kpna2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.130
rps3a	ribosomal protein S3A	0.130	Human Worm
tuba1	tubulin, alpha 1	0.130	Zebrafish
cmyb	transcription factor cmyb	0.129
pak2b	p21 (CDKN1A)-activated kinase 2b	0.129	Human Yeast
col8a1a	collagen, type VIII, alpha 1a	0.129
LOC560602	novel protein similar to vertebrate solute carrier family 2 (facilitated glucose transporter), member 6 (SLC2A6)	0.128
jak1	Janus kinase 1	0.128
stxbp2	syntaxin binding protein 2	0.128
rpl15	ribosomal protein L15	0.127	Worm
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.127
sf3b1	splicing factor 3b, subunit 1	0.127
slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.127
tia1l	cytotoxic granule-associated RNA binding protein 1, like	0.126
ptpn11a	protein tyrosine phosphatase, non-receptor type 11, a	0.126	Fly
bmp3	bone morphogenetic protein 3	0.126
crabp2b	cellular retinoic acid binding protein 2, b	0.126
slc2a1b	solute carrier family 2 (facilitated glucose transporter), member 1b	0.126	Zebrafish
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.126
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.126
acsl4a	acyl-CoA synthetase long-chain family member 4a	0.126
desma	desmin a	0.125
nae1	nedd8 activating enzyme E1 subunit 1	0.125	Human
caspb	caspase b and caspase b-like	0.125
h2afv	H2A histone family, member V	0.124
cdh1	cadherin 1, epithelial	0.124	Mouse
lmo4a	LIM domain only 4a	0.124
rpl23	ribosomal protein L23	0.123
txnrd1	thioredoxin reductase 1	0.122
hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	0.122
ext1c	exostoses (multiple) 1c	0.121
rnd3a	Rho family GTPase 3a	0.120
galcb	galactosylceramidase b	0.120
smad2	MAD homolog 2 (Drosophila)	0.120
ptpra	protein tyrosine phosphatase, receptor type, A	0.120
nt5e	5'-nucleotidase, ecto (CD73)	0.119
rpl8	ribosomal protein L8	0.119
hdac4	histone deacetylase 4	0.119
krt5	keratin 5	0.119	Mouse
dag1	dystroglycan 1	0.119
hdac3	histone deacetylase 3	0.118	Worm
rag1	recombination activating gene 1	0.118	Mouse
rpl7l1	ribosomal protein L7-like 1	0.117
ppp2cb	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	0.117	Mouse
gdpd3	glycerophosphodiester phosphodiesterase domain containing 3	0.117
zgc:110460	zgc:110460	0.117
dnm1l	dynamin 1-like	0.117	Human Worm
farsb	phenylalanyl-tRNA synthetase, beta subunit	0.117
msxc	muscle segment homeobox C	0.117	Zebrafish Worm
osr1	odd-skipped related 1 (Drosophila)	0.116	Mouse
casp8	caspase 8, apoptosis-related cysteine peptidase	0.116
s100a10b	S100 calcium binding protein A10b	0.116
inhbaa	inhibin, beta Aa	0.116	Human
atp2a2b	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2b	0.115	Worm
slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	0.115
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.114
pomca	proopiomelanocortin a	0.114
ube2q2	ubiquitin-conjugating enzyme E2Q family member 2	0.114
aox3	aldehyde oxidase 3	0.113
cdc37	cell division cycle 37 homolog (S. cerevisiae)	0.113
ifnphi1	interferon phi 1	0.112
gro2	groucho 2	0.112
zfyve26	zinc finger, FYVE domain containing 26	0.111
id2a	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a	0.111
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.111
tnc	tenascin C	0.111
spry2	sprouty homolog 2	0.110
rest	RE1-silencing transcription factor	0.110	Human
irx4a	iroquois homeobox protein 4a	0.110
cct4	chaperonin containing TCP1, subunit 4 (delta)	0.110	Worm
tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.110	Zebrafish Mouse Rat
rhoab	ras homolog gene family, member Ab	0.109
mtdha	metadherin a	0.109
rpl36	ribosomal protein L36	0.108
neurog1	neurogenin 1	0.108
mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.108
hoxb1b	homeo box B1b	0.108
bmp8a	bone morphogenetic protein 8a	0.108
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.108	Rat
ck2a2a	casein kinase 2 alpha 2a	0.108
sgk1	serum/glucocorticoid regulated kinase 1	0.107	Rat
zc4h2	zinc finger, C4H2 domain containing	0.107
rbp1a	retinol binding protein 1a, cellular	0.107
etf1	eukaryotic translation termination factor 1	0.107
mcm5	MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)	0.106
midn	midnolin	0.106
esr2b	estrogen receptor 2b	0.106	Mouse Rat
cyp3c1	cytochrome P450, family 3, subfamily c, polypeptide 1	0.106
si:ch211-215h6.2	si:ch211-215h6.2	0.106
wnt9b	wingless-type MMTV integration site family, member 9B	0.105
ccdc94	coiled-coil domain containing 94	0.105
si:ch211-254d18.3	si:ch211-254d18.3	0.105
pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.105
surf6	surfeit 6	0.104
cct3	chaperonin containing TCP1, subunit 3 (gamma)	0.104
bida	BH3 interacting domain death agonist	0.104
ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.104
tgif1	TGFB-induced factor homeobox 1	0.104
atp6v1c1b	ATPase, H+ transporting, lysosomal, V1 subunit C, isoform 1b	0.104	Worm
prrx1a	paired related homeobox 1a	0.104
chek1	CHK1 checkpoint homolog (S. pombe)	0.104
igf1	insulin-like growth factor 1	0.104
zgc:110259	zgc:110259	0.104	Mouse
sox17	SRY-box containing gene 17	0.103	Fly
atp1b3b	ATPase, Na+/K+ transporting, beta 3b polypeptide	0.103
phlda2	pleckstrin homology-like domain, family A, member 2	0.103
rpl10	ribosomal protein L10	0.103
phox2a	paired-like homeobox 2a	0.102
zff9	zinc finger protein 9	0.102
vax1	ventral anterior homeobox 1	0.102
cotl1	coactosin-like 1 (Dictyostelium)	0.102
ankrd13c	ankyrin repeat domain 13C	0.102	Human
esrra	estrogen-related receptor alpha	0.101
ssrp1a	structure specific recognition protein 1a	0.101
erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog	0.101	Rat Fly
jag1b	jagged 1b	0.101
etv2	ets variant gene 2	0.101
pcdh8	protocadherin 8	0.100
hif1an	hypoxia-inducible factor 1, alpha subunit inhibitor	0.100
sulf2	sulfatase 2	0.100
snrpc	small nuclear ribonucleoprotein polypeptide C	0.100
pccb	propionyl Coenzyme A carboxylase, beta polypeptide	0.100
yap1	Yes-associated protein 1	0.100	Mouse Fly
aldh2b	aldehyde dehydrogenase 2b	0.100	Rat
stc1l	stanniocalcin 1, like	0.100
dlx6a	distal-less homeobox gene 6a	0.099
ptk2.1	protein tyrosine kinase 2a	0.099	Human Rat
copb1	coatomer protein complex, subunit beta 1	0.099
ctr9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.099
insrb	insulin receptor b	0.099	Zebrafish
gdf6a	growth differentiation factor 6a	0.098
msna	moesin a	0.098	Worm
icn	ictacalcin	0.098
eprs	glutamyl-prolyl-tRNA synthetase	0.097
hadha	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit	0.097
eif5a	eukaryotic translation initiation factor 5A	0.097	Worm Fly
nkx2.1a	NK2 homeobox 1a	0.097
il8	interleukin 8	0.097
eif2s1l	eukaryotic translation initiation factor 2, subunit 1 alpha, like	0.097
atf3	activating transcription factor 3	0.097
oprm1	opioid receptor, mu 1	0.097
zgc:56200	zgc:56200	0.097
cops3	COP9 constitutive photomorphogenic homolog subunit 3	0.096
sirt1	sirtuin (silent mating type information regulation 2 homolog) 1	0.096
foxa3	forkhead box A3	0.096	Fly
dmrt3a	doublesex and mab-3 related transcription factor 3a	0.096	Zebrafish
eng2a	engrailed 2a	0.096
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.095
aldh7a1	aldehyde dehydrogenase 7 family, member A1	0.095
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.095
si:ch211-235f6.2	si:ch211-235f6.2	0.095
brd4	bromodomain containing 4	0.095
eif2s2	eukaryotic translation initiation factor 2, subunit 2 beta	0.095	Worm
rpl13a	ribosomal protein L13a	0.095
neurod4	neurogenic differentiation 4	0.095
perp	PERP, TP53 apoptosis effector	0.094
cdca8	cell division cycle associated 8	0.094
anp32b	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	0.094	Human
copg2	coatomer protein complex, subunit gamma 2	0.093	Worm
prox1	prospero-related homeobox gene 1	0.093
zgc:100919	zgc:100919	0.093
npc1	Niemann-Pick disease, type C1	0.093
immt	inner membrane protein, mitochondrial (mitofilin)	0.093
dmd	dystrophin	0.093
eif3s6ip	eukaryotic translation initiation factor 3, subunit 6 interacting protein	0.093
dlx3b	distal-less homeobox gene 3b	0.092
axin2	axin 2 (conductin, axil)	0.092
ywhai	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide	0.092	Yeast
kif5bb	kinesin family member 5B, b	0.092
dmrta2	doublesex and mab-3 related transcription factor like family A2	0.092	Zebrafish
wif1	wnt inhibitory factor 1	0.092
sec23a	Sec23 homolog A (S. cerevisiae)	0.091	Worm
gng5	guanine nucleotide binding protein (G protein), gamma 5	0.091
pob	partial optokinetic response b	0.091
per3	period homolog 3 (Drosophila)	0.091
smad1	MAD homolog 1 (Drosophila)	0.091
dusp1	dual specificity phosphatase 1	0.091
adka	adenosine kinase a	0.091
mapkapk2a	mitogen-activated protein kinase-activated protein kinase 2a	0.091
pkd2	polycystic kidney disease 2	0.091
rpl27	ribosomal protein L27	0.090
foxc1a	forkhead box C1a	0.090
pglyrp5	peptidoglycan recognition protein 5	0.090
rela	v-rel reticuloendotheliosis viral oncogene homolog A	0.090
vegfc	vascular endothelial growth factor c	0.089
eif5a2	eukaryotic translation initiation factor 5A2	0.089	Worm
hm13	histocompatibility (minor) 13	0.089
tfe3b	transcription factor binding to IGHM enhancer 3b	0.089
gdnf	glial cell derived neurotrophic factor	0.089	Human Mouse
psmb7	proteasome (prosome, macropain) subunit, beta type, 7	0.089	Worm
hbbe3	hemoglobin beta embryonic-3	0.089
nadl1.1	neural adhesion molecule L1.1	0.089
ctsba	cathepsin B, a	0.089
gdi2	GDP dissociation inhibitor 2	0.089
gle1	GLE1 RNA export mediator homolog (yeast)	0.089
hoxa11b	homeo box A11b	0.088
sox7	SRY-box containing gene 7	0.088	Human Fly
bad	BCL2-antagonist of cell death	0.088
sec61al1	Sec61 alpha like 1	0.088	Worm
cct8	chaperonin containing TCP1, subunit 8 (theta)	0.088
ptgesl	prostaglandin E synthase 2-like	0.088
gabarapa	GABA(A) receptor-associated protein a	0.088	Human
tacc3	transforming, acidic coiled-coil containing protein 3	0.088
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.088
piwil2	piwi-like 2 (Drosophila)	0.087
birc5a	baculoviral IAP repeat-containing 5a	0.087
si:rp71-39b20.7	si:rp71-39b20.7	0.087
rnaset2	ribonuclease T2	0.087
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.087
twist1a	twist1a	0.087
epha4b	eph receptor A4b	0.087
gata2a	GATA-binding protein 2a	0.087	Zebrafish
wu:fb17g07	wu:fb17g07	0.086
lama4	laminin, alpha 4	0.086	Worm
wnt2	wingless-type MMTV integration site family member 2	0.086
zgc:77235	zgc:77235	0.086
jag2	jagged 2	0.086	Mouse
dharma	dharma	0.086
zgc:77051	zgc:77051	0.086
nkx2.3	NK2 transcription factor related 3	0.085
ass1	argininosuccinate synthetase 1	0.085
bmp5	bone morphogenetic protein 5	0.085
pkp3	plakophilin 3	0.085
srf	serum response factor	0.085
mapk3	mitogen-activated protein kinase 3	0.085	Worm
smu1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	0.085
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.085
nod1	nucleotide-binding oligomerization domain containing 1	0.085
evpl	envoplakin	0.085
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.084
hk1	hexokinase 1	0.084
cry1a	cryptochrome 1a	0.084
uxs1	UDP-glucuronic acid decarboxylase 1	0.084
itgb1a	integrin, beta 1a	0.084	Human Worm
grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.083
thbs1	thrombospondin 1	0.083	Human
fancl	Fanconi anemia, complementation group L	0.083
fadd	Fas (tnfrsf6)-associated via death domain	0.083
rbm8a	RNA binding motif protein 8A	0.083	Worm
phf5a	PHD finger protein 5A	0.083
aurka	aurora kinase A	0.083	Mouse
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.083	Mouse
org	oogenesis-related gene	0.083
aldh2a	aldehyde dehydrogenase 2 family (mitochondrial)a	0.082
myst2	MYST histone acetyltransferase 2	0.082
hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase	0.082
pax5	paired box gene 5	0.082
anxa1c	annexin A1c	0.082	Mouse
irx5a	iroquois homeobox protein 5a	0.082
eif4bb	eukaryotic translation initiation factor 4Bb	0.082
hdac1	histone deacetylase 1	0.082	Mouse Worm
fmr1	fragile X mental retardation 1	0.082
exosc2	exosome component 2	0.082
eng2b	engrailed 2b	0.081	Zebrafish
lhb	luteinizing hormone, beta polypeptide	0.081
phox2b	paired-like homeobox 2b	0.081
spon1b	spondin 1b	0.081
prp19	PRP19/PSO4 homolog (S. cerevisiae)	0.081
ncor1	nuclear receptor co-repressor 1	0.081
nudt9	nudix (nucleoside diphosphate linked moiety X)-type motif 9	0.081
mcm7	MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)	0.081
zgc:103652	zgc:103652	0.081
cct2	chaperonin containing TCP1, subunit 2 (beta)	0.081
samm50	sorting and assembly machinery component 50 homolog (S. cerevisiae)	0.081
ntn1a	netrin 1a	0.081	Zebrafish
tomm34	translocase of outer mitochondrial membrane 34	0.080
calcrla	calcitonin receptor-like a	0.080
ved	ventrally expressed dharma/bozozok antagonist	0.080
hoxd11a	homeo box D11a	0.079
elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.079
egln3	egl nine homolog 3 (C. elegans)	0.079	Human Mouse
arfip2a	ADP-ribosylation factor interacting protein 2a	0.079
gng3	guanine nucleotide binding protein (G protein), gamma 3	0.079
eif3m	eukaryotic translation initiation factor 3, subunit M	0.079	Fly
lrpprc	leucine-rich PPR-motif containing	0.079
ppia	peptidylprolyl isomerase A (cyclophilin A)	0.079
sdcbp	syndecan binding protein (syntenin)	0.078
slc2a9l2	solute carrier family 2 (facilitated glucose transporter), member 9-like 2	0.078
LOC100003680	proline-, glutamic acid- and leucine-rich protein 1-like	0.078
dsc2l	desmocollin 2 like	0.078
zfp36l1a	zinc finger protein 36, C3H type-like 1a	0.078	Mouse
tgfbi	transforming growth factor, beta-induced	0.078
stk24b	serine/threonine kinase 24b (STE20 homolog, yeast)	0.078	Human Worm
ndr2	nodal-related 2	0.078
anxa1a	annexin A1a	0.078	Mouse
lman2	lectin, mannose-binding 2	0.078
hsp90b1	heat shock protein 90, beta (grp94), member 1	0.077	Human
zgc:63663	zgc:63663	0.077
lama5	laminin, alpha 5	0.077	Worm
hoxa9a	homeo box A9a	0.077
diaph2	diaphanous homolog 2 (Drosophila)	0.077
tgfb2	transforming growth factor, beta 2	0.077	Human Mouse Rat
smc3	structural maintenance of chromosomes 3	0.077
kal1b	Kallmann syndrome 1b sequence	0.077
pvalb8	parvalbumin 8	0.077
tbx16	T-box gene 16	0.077
rab1a	RAB1A, member RAS oncogene family	0.077	Worm
plekhg5a	pleckstrin homology domain containing, family G (with RhoGef domain) member 5a	0.077
rps26l	ribosomal protein S26, like	0.077	Worm
htr1aa	5-hydroxytryptamine (serotonin) receptor 1A a	0.076
frem2a	Fras1 related extracellular matrix protein 2a	0.076
ube2d1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.076
zgc:110116	zgc:110116	0.076
slc4a4a	solute carrier family 4, member 4a	0.076
itgb1b.2	integrin, beta 1b.2	0.076	Human Worm
slc2a12	solute carrier family 2 (facilitated glucose transporter), member 12	0.076
rybpa	RING1 and YY1 binding protein a	0.076
snx9l	sorting nexin 9-like	0.076
stil	TAL1 (SCL) interrupting locus	0.075	Mouse
fsta	follistatin a	0.075
entpd3	ectonucleoside triphosphate diphosphohydrolase 3	0.075
copb2	coatomer protein complex, subunit beta 2	0.075	Worm
dazl	daz-like gene	0.075
rpl4	ribosomal protein L4	0.075	Worm
otpb	orthopedia homolog b	0.075
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.075
cldna	claudin a	0.075
LOC799612	prolactin 2	0.075
rpl22l1	ribosomal protein L22-like 1	0.075
appb	amyloid beta (A4) precursor protein b	0.074	Human Mouse
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.074
eif1axb	eukaryotic translation initiation factor 1A, X-linked, b	0.074
si:dkey-18f23.10	si:dkey-18f23.10	0.074
her15.1	hairy and enhancer of split-related 15.1	0.074
mef2d	myocyte enhancer factor 2d	0.074
satb2	SATB homeobox 2	0.074
nadl1.2	neural adhesion molecule L1.2	0.074
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.073
tnfsf10l2	tumor necrosis factor (ligand) superfamily, member 10 like 2	0.073	Human Zebrafish Fly
myd88	myeloid differentiation primary response gene (88)	0.073
tuba8l	tubulin, alpha 8 like	0.073	Zebrafish
itga3b	integrin, alpha 3b	0.073
mecp2	methyl CpG binding protein 2	0.073	Mouse
srm	spermidine synthase	0.073
rpl14	ribosomal protein L14	0.073	Fly
pknox2	pbx/knotted 1 homeobox 2	0.073
gnai2l	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like	0.073
sod2	superoxide dismutase 2, mitochondrial	0.072	Human Mouse
fabp2	fatty acid binding protein 2, intestinal	0.072
ctsl1a	cathepsin L, 1 a	0.072
rasl11b	RAS-like, family 11, member B	0.072
nrp2a	neuropilin 2a	0.072
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.072
mmp2	matrix metalloproteinase 2	0.072
prl	prolactin	0.072
ppp2r1b	protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform	0.072	Human Worm
dus1l	dihydrouridine synthase 1-like (S. cerevisiae)	0.072
loxl3b	lysyl oxidase-like 3b	0.072
mpx	myeloid-specific peroxidase	0.072
mettl3	methyltransferase like 3	0.072
rps27a	ribosomal protein S27a	0.072	Worm
snrnp27	small nuclear ribonucleoprotein 27 (U4/U6.U5)	0.072
angpt2	angiopoietin 2	0.072
tubb5	tubulin, beta 5	0.072
papss2b	3'-phosphoadenosine 5'-phosphosulfate synthase 2b	0.072
atf4b2	activating transcription factor 4b2	0.071	Mouse
bcl2l10	BCL2-like 10 (apoptosis facilitator)	0.071
eif4a1a	eukaryotic translation initiation factor 4A, isoform 1A	0.071
ca15b	carbonic anhydrase XV b	0.071
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.071
tbca	tubulin cofactor a	0.071
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.071	Zebrafish
cdk2	cyclin-dependent kinase 2	0.071
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.071
nusap1	nucleolar and spindle associated protein 1	0.071
sox11b	SRY-box containing gene 11b	0.071
smn1	survival motor neuron 1	0.071
sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.071
mmp13a	matrix metalloproteinase 13a	0.071
atp6v1d	ATPase, H+ transporting, V1 subunit D and ATPase, H+ transporting, V1 subunit D	0.070	Worm
tph2	tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)	0.070
nkapl	NFKB activating protein-like	0.070
pou5f1	POU domain, class 5, transcription factor 1	0.070
foxi3a	forkhead box I3a	0.070
fzd5	frizzled homolog 5	0.070	Mouse
nr1i2	nuclear receptor subfamily 1, group I, member 2	0.070
maptb	microtubule-associated protein tau b	0.070
dusp5	dual specificity phosphatase 5	0.070
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.070
tp53bp2	tumor protein p53 binding protein, 2	0.070
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.070
tpm3	tropomyosin 3	0.070
hspa8	heat shock protein 8	0.069	Worm
dbh	dopamine beta hydroxylase	0.069	Mouse
csnk1g2a	casein kinase 1, gamma 2a	0.069
sumo2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.069
helt	hey-like transcription factor	0.069
etv5b	ets variant 5b	0.069
bms1l	BMS1-like, ribosome assembly protein (yeast)	0.069
fgf4	fibroblast growth factor 4	0.069	Zebrafish Mouse
hspa9	heat shock protein 9	0.068
thrb	thyroid hormone receptor beta	0.068
hspb1	heat shock protein, alpha-crystallin-related, 1	0.068	Mouse
raf1a	v-raf-1 murine leukemia viral oncogene homolog 1a	0.068
rhag	Rhesus blood group-associated glycoprotein	0.068
eml2	echinoderm microtubule associated protein like 2	0.068
nuf2	NUF2, NDC80 kinetochore complex component, homolog	0.068
pfn2l	profilin 2 like	0.068
sulf2l	sulfatase 2, like	0.068
glcci1	glucocorticoid induced transcript 1	0.068
wnt1	wingless-type MMTV integration site family, member 1	0.068
tbc1d23	TBC1 domain family, member 23	0.068
dab1a	disabled homolog 1a (Drosophila)	0.068
clu	clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)	0.068	Human
sf3b4	splicing factor 3b, subunit 4	0.068
rpl34	ribosomal protein L34	0.068
foxe3	forkhead box E3	0.068
rnf41	ring finger protein 41	0.068	Human
cnot1	CCR4-NOT transcription complex, subunit 1	0.067
sf3a2	splicing factor 3a, subunit 2	0.067
cdh23	cadherin-like 23	0.067
tlx2	T-cell leukemia, homeobox 2	0.067
slc25a3b	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b	0.067
zgc:123327	zgc:123327	0.067
chuk	conserved helix-loop-helix ubiquitous kinase	0.067
nucks1a	nuclear casein kinase and cyclin-dependent kinase substrate 1a	0.067
kitb	kit receptor b	0.067	Zebrafish Fly
slc3a2	solute carrier family 3, member 2	0.067
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.067
eif4e1c	eukaryotic translation initiation factor 4E family member 1c	0.067
LOC100000687	signal peptide, CUB and EGF-like domain-containing protein 3-like	0.067
prdx2	peroxiredoxin 2	0.067	Human Mouse
rps15	ribosomal protein S15	0.067	Worm
lbr	lamin B receptor	0.066
rab22a	RAB22A, member RAS oncogene family	0.066
rrm2	ribonucleotide reductase M2 polypeptide	0.066
gsx1	GS homeobox 1	0.066
oprd1a	opioid receptor, delta 1a	0.066
pcdh18b	protocadherin 18b	0.066
calm1b	calmodulin 1b	0.066
cry5	cryptochrome 5	0.065
zgc:110113	zgc:110113	0.065
ccne2	cyclin E2	0.065	Fly
tfpi2	tissue factor pathway inhibitor 2	0.065
LOC565594	similar to glycoprotein (predicted)	0.065
derl1	Der1-like domain family, member 1	0.065
hoxa1a	homeo box A1a	0.065
ybx1	Y box binding protein 1	0.064
eif3c	eukaryotic translation initiation factor 3, subunit C	0.064	Worm
kidins220b	kinase D-interacting substrate of 220b	0.064
ephb3a	eph receptor B3a	0.064
duox	dual oxidase	0.064	Fly
ap2a1	adaptor-related protein complex 2, alpha 1 subunit	0.064
flncb	filamin C, gamma b (actin binding protein 280)	0.064
unc5b	unc-5 homolog B (C. elegans)	0.064	Human Rat
rps9	ribosomal protein S9	0.063
rpn2	ribophorin II	0.063
uba52	ubiquitin A-52 residue ribosomal protein fusion product 1	0.063
hbbe1.1	hemoglobin beta embryonic-1.1	0.063